Did You Know...
...Chester Carlson was a patent agent who tired of having to make multiple copies of patent applications using the only duplication method available at the time: carbon paper. In 1959 he came up with a new copying system and took it to IBM for evaluation. The "experts" at IBM determined potential sales to be only 5,000 units because people wouldn't want to use a bulky machine when they had carbon paper. Carlson's invention was the xerography process, the company founded on the system is Xerox.
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| Number | Title | Issue Date |
| 8173402 | Modified yeasts and uses thereof, in particular for producing steroid derivatives The present invention relates to novel yeast strains, methods and genetic constructs for their preparation, and their use for the synthesis or modification of steroidal compounds. More particularly, the invention describes strains having a reduced 20αHSD type activ... | 05/08/2012 |
| 8137940 | Method for production of biomass using a gluconobacter oxydans comprising an inactivated NADP dependent glucose dehydrogenase gene The present invention relates to microorganisms genetically engineered to increase yield and/or efficiency of biomass production from a carbon source, such as e.g. glucose. Processes for generating such microorganisms are also provided by the present invention. The ... | 03/20/2012 |
| 8114641 | Methylbutanol as an advanced biofuel This invention describes genes, metabolic pathways, microbial strains and methods to produce methyl butanol and other compounds of interest from renewable feedstocks. ... | 02/14/2012 |
| 8105808 | Anaerobic microbial composition and methods of using same A microbial composition for concurrent dechlorination of a mixture of chlorinated ethanes and chlorinated ethenes includes a isolated consortium of bioremediative microorganisms comprising strains of microorganism comprising Clostridium, Acetobacterium, Dehalobac... | 01/31/2012 |
| 8097438 | Nucleic acids encoding modified cytochrome P450 enzymes and methods of use thereof The present invention provides nucleic acids comprising nucleotide sequences encoding modified cytochrome P450 enzymes; as well as recombinant vectors and host cells comprising the nucleic acids. The present invention further provides methods of producing a function... | 01/17/2012 |
| 8076109 | Processes for producing a fermentation product The present invention relates to processes for producing a fermentation product, such as ethanol, from milled starch-containing material comprising (a) saccharifying the milled starch-containing material with a glucoamylase having an amino acid sequence shown in SEQ... | 12/13/2011 |
| 8058037 | Protein and DNA encoding the protein The present invention provides a protein comprising the amino acid sequence as shown in any one of SEQ ID NOS: 1 to 3 (except for proteins of the amino acid sequences as shown in SEQ ID NOS: 4 to 6), and a process for industrially advantageously producing a compound... | 11/15/2011 |
| 8026085 | Methods and systems for selective fluorination of organic molecules A method and system for selectively fluorinating organic molecules on a target site wherein the target site is activated and then fluorinated are shown together with a method and system for identifying a molecule having a biological activity. ... | 09/27/2011 |
| 7977075 | Materials and methods for the efficient production of acetate and other products The subject invention provides materials and methods wherein unique and advantageous combinations of gene mutations are used to direct carbon flow from sugars to a single product. The techniques of the subject invention can be used to obtain products from native pat... | 07/12/2011 |
| 7807424 | Methods of producing polyketide synthase mutants and compositions and uses thereof The present invention comprises crystalline polyketide synthases, isolated non-native polyketide synthases having the structural coordinates of said crystalline polyketide synthases, and nucleic acid encoding such non-native polyketide synthases. Also disclosed are ... | 10/05/2010 |
| 7622283 | Methods for synthesizing mevalonate Methods for synthesizing isopentenyl pyrophosphate are provided. A first method comprises introducing into a host microorganism a plurality of heterologous nucleic acid sequences, each coding for a different enzyme in the mevalonate pathway for producing isopentenyl... | 11/24/2009 |
| 7622282 | Biosynthesis of isopentenyl pyrophosphate Methods for synthesizing isopentenyl pyrophosphate are provided. A first method comprises introducing into a host microorganism a plurality of heterologous nucleic acid sequences, each coding for a different enzyme in the mevalonate pathway for producing isopentenyl... | 11/24/2009 |
| 7432074 | Method for extracting a macrolide from biomatter Provided is a method for obtaining a macrolide, especially tacrolimus, from biomatter. ... | 10/07/2008 |
| 7432102 | Transformants producing substance pf1022 derivatives, methods for producing the same, and novel biosynthesis genes An objective of the present invention is to provide a method for producing substance PF1022 derivatives, in particular PF1022-220 and PF1022-260, by a direct fermentation method, and a transformant to be used for this method. According to the present invention, ther... | 10/07/2008 |
| 7432090 | Blocking sporulation by inhibiting SpoIIE We have shown that the control of solventogenesis and sporulation can be genetically uncoupled in C. acetobutylicum. In strain 824(pASspo), the absence of SpoIIE causes sporulation to be blocked at stage II. The cell remains in a vegetative state, and this al... | 10/07/2008 |
| 7425433 | Carboxylic acid reductase polypeptide, nucleotide sequence encoding same and methods of use The invention provides the nucleotide sequence and amino acid sequence for the enzyme carboxylic acid reductase isolated from bacteria. Expression cassettes, vectors, transformed cells, and variants are also provided as methods for use of recombinant biocatalytic re... | 09/16/2008 |
| 7419813 | Fructosyl peptide oxidase The present invention has an object of providing a novel fructosyl peptide oxidase having superior physicochemical properties such as stability that is useful as an enzyme for clinical diagnosis, and an object of providing a method for producing the fructosyl peptid... | 09/02/2008 |
| 7416866 | Process for the overexpression of dehydrogenases A process for the overexpression of dehydrogenases, especially for the overexpression of Δ1-dehydrogenases, in particular for the overexpression of 3-keto steroid-Δ1-dehydrogenases, as well as for the bacteria, plasmids and DNA sequences that... | 08/26/2008 |
| 7402417 | P450 oxygenases and methods of use This disclosure provides the nucleic acid and protein sequences of novel P450 oxygenases that utilize, at least, taxoid substrates, including taxadiene isomers. The disclosed oxygenases, such as a taxoid 5α-hydroxylase, hydroxylate, at least, the C5 position of a t... | 07/22/2008 |
| 7374926 | Enantioconvergent chemoenzymatic synthesis of ()-γ-amino-β-hydroxybutyric acid (()-GABOB) The present invention particularly relates to a chemoenzymatic process for the stereoselective preparation of both enantiomers of 3-hydroxy-4-trityloxy butanenitrile key intermediates for the preparation of (R)-GABOB by lipase mediated kinetic resolution of its race... | 05/20/2008 |
| 7332297 | Enzymatic polymerization The invention relates to a novel method for enzymatic polymerization which includes (1) obtaining a reaction mixture including a monomer, a template, and an enzyme; and (2) incubating the reaction mixture for a time and under conditions sufficient for the monomer to... | 02/19/2008 |
| 7326549 | Myo-inositol oxygenases The invention provides methods and materials related to the production of organic products such as glucuronic acid, ascorbic acid, and glucaric acid. Specifically, the invention provides cells, methods for culturing cells, isolated nucleic acid molecules, and method... | 02/05/2008 |
| 7312048 | Recombinant production of novel polyketides Novel polyketides and novel methods of efficiently producing both new and known polyketides, using recombinant technology, are disclosed. In particular, a novel host-vector system is described which is used to produce polyketide synthases which in turn catalyze the ... | 12/25/2007 |
| 7309591 | Method for the production of resveratrol in cell cultures The invention relates to a method for the production of resveratrol in cell cultures. The inventive method consists in: incubating a culture of cells which produce resveratrol naturally, in suspension, in the presence of randomly-methylated β-cyclodextrin (RMBCD) w... | 12/18/2007 |
| 7309582 | Polymer-template complex produced by enzymatic polymerization The invention relates to a novel method for enzymatic polymerization which includes (1) obtaining a reaction mixture including a monomer, a template, and an enzyme; and (2) incubating the reaction mixture for a time and under conditions sufficient for the monomer to... | 12/18/2007 |
| 7288689 | Methanol and fuel alcohol production for an oxygenate to olefin reaction system The present invention provides various processes for producing C1 to C4 alcohols, optionally in a mixed alcohol stream, and optionally converting the alcohols to light olefins. In one embodiment, the invention includes directing a first portion of a syngas stream to... | 10/30/2007 |
| 7267975 | Methods and compositions relating to insect repellents from a novel endophytic fungus The present invention relates to the discovery of a novel endophytic fungus, Muscodor vitigenus, from the liana, Paullinia paullinioides. This fungus produces naphthalene under certain cultural conditions that has chromatographic and mass spectral prop... | 09/11/2007 |
| 7253206 | Phenalenone derivatives, processes for preparation and use thereof The present invention provides novel phenalenone derivatives of formula (I) which are formed by the microorganism Penicillium herquei Bainer & Sartory, DSM 14142, during fermentation. A process for their preparation, their use as pharmaceutical compositions, ... | 08/07/2007 |
| 7232664 | Fermentation process using specific oxygen uptake rates as a process control Specific oxygen uptake (OUR) is used as a process control parameter in fermentation processes. OUR is determined during at least the production phase of a fermentation process, and process parameters are adjusted to maintain the OUR within desired ranges. The invent... | 06/19/2007 |
| 7226764 | Compositions and methods for the synthesis and subsequent modification of uridine-5′-diphosphosulfoquinovose (UDP-SQ) The present invention is directed to compositions and methods related to the synthesis and modification of uridine-5′-diphospho-sulfoquinovose (UDP-SQ). In particular, the methods of the present invention comprise the utilization of recombinant enzymes from Ara... | 06/05/2007 |
| 7223575 | pentose-sugar fermenting strains and uses thereof Disclosed in the present invention is a Zymomonas integrant and derivatives of these integrants that posses the ability to ferment pentose into ethanol. The genetic sequences encoding for the pentose-fermenting enzymes are integrated into the Zymomonas | 05/29/2007 |
| 7214507 | Plant enzymes for bioconversion The invention provides a method for converting sesquiterpene. The method includes reacting a sesquiterpene substract with a sesquiterpene converting enzyme. The enzyme is from a species or organism containing sesquiterpenes. The sesquiterpene substrate is not natura... | 05/08/2007 |
| 7199276 | Controlling the ratio of ethylene to propylene produced in an oxygenate to olefin conversion process The present invention provides various processes for producing methanol and ethanol, preferably in a mixed alcohol stream. In one embodiment, the invention includes directing syngas to a synthesis zone wherein the syngas contacts a methanol synthesis catalyst and an... | 04/03/2007 |
| 7196239 | Methanol and ethanol production for an oxygenate to olefin reaction system The present invention provides various processes for producing light olefins from methanol and ethanol, optionally in a mixed alcohol stream. In one embodiment, the invention includes directing a first syngas stream to a methanol synthesis zone to form methanol and ... | 03/27/2007 |
| 7195898 | Method for the production of -hydroxybenzoate in species of pseudomonas and Bacterial strains transformed with the pcu genes are useful for the production of para-hydroxybenzoate (PHBA). Applicant has provided the p-cresol utilizing (pcu) and tmoX gene sequences from Pseudomonas mendocina KR-1, the proteins encoded by these sequences... | 03/27/2007 |
| 7189544 | Enzymatic modification of lecithin The disclosure pertains to enzymatic modification of lecithin and to hydrolyzed lecithin products obtained by such modification. One particular implementation provides methods for producing a hydrolyzed lecithin product containing hydrolyzed phospholipids, monoglyce... | 03/13/2007 |
| 7189545 | Production and use of pyruvate decarboxylase A polypeptide with pyruvate decarboxylase activity, derived from the pyruvate decarboxylase from Zymomonas mobilis by substitution of an amino acid in position 553. ... | 03/13/2007 |
| 7172886 | Biosynthesis of isopentenyl pyrophosphate Methods for synthesizing isopentenyl pyrophosphate are provided. A first method comprises introducing into a host microorganism a plurality of heterologous nucleic acid sequences, each coding for a different enzyme in the mevalonate pathway for producing isopentenyl... | 02/06/2007 |
| 7169591 | Preparation of enantio-specific epoxides A method for converting alkenes into epoxides and, particularly, to convert alkenes into enantio-specific epoxides by the use of enzymes which may be in their naturally-occuring (native) form or in mutated form, such as a native or mutated non-haem diiron-containing... | 01/30/2007 |
| 7098368 | Hydrogenation of biochemical derived 1,3 -propanediol The invention discloses a hydrogenation process for removing impurities and controlling acid for use in downstream processing of biochemically-derived 1,3-propanediol. Preferably, the biochemically-derived 1,3-propanediol, before the contacting, has an initial color... | 08/29/2006 |
