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| Number | Title | Issue Date |
| 8153406 | Microorganism A microorganism which is Rhodococcus rhodochrous strain NCIMB 41164 or a mutant thereof. A method of culturing the microorganism in a culture medium comprising urea or urea derivative is claimed. A nitrile hydratase obtainable from the microorganism is claime... | 04/10/2012 |
| 8143033 | Process for producing (meth)acrylamide A process for producing (meth)acrylamide using a microbial catalyst, wherein production steps can be simplified and production cost can be reduced. The process for producing (meth)acrylamide of the present involves (a) a step of allowing (meth)acrylonitrile to under... | 03/27/2012 |
| 8062870 | Enantiomerically resolving acyloxyalkyl thiocarbonates used in synthesizing acyloxyalkyl carbamate prodrugs Methods of enzymatically resolving acyloxyalkyl thiocarbonates useful in the synthesis of acyloxyalkyl carbamate prodrugs are disclosed. ... | 11/22/2011 |
| 7993886 | Catalyzed preparation of (meth)acrylates of N-hydroxyalkylated amides The claimed invention relates to a process for preparing (meth)acrylates of N-hydroxyalkylated amides, in which open-chain N-hydroxyalkylated amides are esterified with (meth)acrylic acid or transesterified with at least one (meth)acrylic ester in the presence of at... | 08/09/2011 |
| 7838271 | Microbiological method for producing amides The present invention provides for microorganisms capable of tolerating acetonitrile concentrations of at least 3 M, enzyme extracts obtainable from these microorganisms, a nitrile hydratase obtainable from these microorganisms, a method for preparing amides using t... | 11/23/2010 |
| 7820416 | Process for producing amide compound and acrylamide polymer In a method for producing an amide compound of the present invention including obtaining an amide compound from a nitrile compound using a microbial catalyst and transferring a solution containing the microbial catalyst and the amide compound, a positive-displacemen... | 10/26/2010 |
| 7816106 | Manufacture of amides A method of producing an amide from the corresponding nitrile comprising the following steps, i) providing a microorganism capable of producing a nitrile hydratase biocatalyst, ii) culturing the microorganism in a growth medium, iii) storing the microorganism, iv) c... | 10/19/2010 |
| 7749739 | Process for producing amide compound using microbial catalyst This invention relates to a process for producing an amide compound from a nitrile compound using a microbial catalyst, wherein a microbial cell having nitrile hydratase activity of 50 U or higher per mg of dry cell at a reaction temperature of 10° C. is brought in... | 07/06/2010 |
| 7700330 | Method of purifying amide compound The invention is to provide a process for effectively removing impurities contained in an amide compound-containing solution by making an amide compound-containing solution, particularly an amide compound-containing solution produced by a hydration reaction of a nit... | 04/20/2010 |
| 7666635 | Process for the preparation of amides A novel biotechnological process for the preparation of nitriles, starting from amides, is described. Micro-organisms of the genus Amycolatopsis, Actinomadura or Rhodococcus are employed for this process. ... | 02/23/2010 |
| 7595178 | Process for the preparation of amides A novel biotechnological process for the preparation of nitrites, starting from amides, is described. Microorganisms of the genus Amycolatopsis, Actinomadura or Rhodococcus are employed for this process. ... | 09/29/2009 |
| 7592164 | Process for preparing unsaturated amides and carboxylic acids A process of producing an amide from a nitrile by the action of a nitrile hydratase enzyme or ammonium salt of an ethylenically unsaturated carboxylic acid from an amide by the action of amidase respectively in which enzymes are obtainable from a microorganism of th... | 09/22/2009 |
| 7592165 | Process for the enzymatic preparation of an amide from a nitrile Disclosed herein are cyanide-tolerant nitrile hydratases especially from Pseudomonas putida or Pseudomonas marginalis strains which exhibit increased cyanide tolerance. Also disclosed are methods of preparing amides from nitriles in the presence of cya... | 09/22/2009 |
| 7553646 | Microbial sulfoxidation and amidation of benzhdrylsulfanyl carboxylic acids and uses thereof The present invention provides novel methods for the synthesis of racemic and enantiomers of modafinil via microbial oxidation-amidation transformation. The methods include the successive oxidation-amidation of benzhydrylsulfanyl carboxylic acid to produce racemic a... | 06/30/2009 |
| 7491521 | Rhodococcus nitrile hydratase The invention relates to a Rhodococcus polynucleotide cluster which contains nucleotide sequences which encode polypeptides having the activity of a nitrile hydratase, of an auxiliary protein P15K which activates this enzyme and of a cobalt transporter... | 02/17/2009 |
| 7405064 | Nucleic acid fragments encoding nitrile hydratase and amidase enzymes from 5-MGAM-4D and recombinant organisms expressing those enzymes useful for the production of amides and acids The invention relates to the isolation, sequencing, and recombinant expression of genes encoding either a nitrile hydratase (NHase) or amidase (Am) from Comamonas testosteroni 5-MGAM-4D, where the NHase is useful for catalyzing the hydration of nitriles to th... | 07/29/2008 |
| 7399616 | Enzymatic synthesis of N-acyl-L-arginine esters The invention relates to a process for preparing a Na-acyl-L-arginine ester, derived from fatty acids and esterified dibasic amino acids, according to the following formula (I), where: X— is Br—, Cl—, or HSO4— R1: is linear alkyl chain from an saturated fatt... | 07/15/2008 |
| 7344868 | Method for synthesizing ceramide-type compounds The invention relates to the fields of fatty substance chemistry, specifically of the ceramide-type compound synthesis. The invention resides substantially in the synthesis of ceramide-type compounds. Specifically, the aim of the invention is a new enzymatic synthes... | 03/18/2008 |
| 7316918 | Process for the preparation of (−) modafinil An enzymatic process for the preparation of intermediates useful in the synthesis of (−) modafinil. ... | 01/08/2008 |
| 7309590 | Method for producing an aqueous acrylamide solution with a biocatalyst The invention relates to a method and device for producing an aqueous acrylamide solution by hydrating acrylonitrile in an aqueous solution while in the presence of a biocatalyst. ... | 12/18/2007 |
| 7294493 | Nucleic acid fragments encoding nitrile hydratase and amidase enzymes from 5-MGAM-4D and recombinant organisms expressing those enzymes useful for the production of amides and acids The invention relates to the isolation, sequencing, and recombinant expression of genes encoding either a nitrile hydratase (NHase) or amidase (Am) from Comamonas testosteroni 5-MGAM-4D, where the NHase is useful for catalyzing the hydration of nitriles to th... | 11/13/2007 |
| 7288402 | Rhodococcus nitrile hydratase The invention relates to a Rhodococcus polynucleotide cluster which contains nucleotide sequences which encode polypeptides having the activity of a nitrile hydratase, of an auxiliary protein P15K which activates this enzyme and of a cobalt transporter, to tr... | 10/30/2007 |
| 7247462 | Coated enzyme-containing catalyst An enzymatic catalyst in the granular form which is non-dispersible in water comprising an inner core provided with a coating which coating comprises an enzymatic material characterised in that the coating has a thickness of from 30 to 400 microns and the ratio of t... | 07/24/2007 |
| 7244595 | Method of maintaining or improving a nitrile hydratase activity The object of this invention is to provide a method which not only maintains the nitrile hydratase activity of a nitrile hydratase-containing cell or a treated material of the cell under conditions where the cell does not grow, but also improves the nitrile hydratas... | 07/17/2007 |
| 7241602 | Nucleic acid sequences encoding enantioselective amidases The invention relates to nucleic acid sequence encoding enantioselective amides with an amino acid sequence of SEQ ID NO: 2. The invention also relates to a process for fermentation, comprising a batch and a feed phase, of a microorganism in a fermentation medium, w... | 07/10/2007 |
| 7238503 | Process for making fluoroleucine ethyl esters The instant invention describes a novel reaction that includes spontaneous racemization of an azalactone via enol tautomerization. This racemization results in improved yield and ee over other reactions previously described. ... | 07/03/2007 |
| 7208631 | 2-alkylcysteinamide or salt thereof, process for producing these, and use of these A process for producing a 2-alkylcysteinamide, which comprises hydrolysis of a 4-alkylthiazolidine-4-carboxamide represented by the general formula (2) or a salt thereof: wherein R represents a lower alkyl group ... | 04/24/2007 |
| 7205133 | Process for producing acrylamide using a microbial catalyst having been washed with aqueous acrylic acid solution Provided is a process for producing acrylamide with good storage stability and improved acrylamide polymer physical properties using a microbial catalyst. A microbial catalyst having catalytic activity to convert from acrylonitrile to acrylamide is washed with an aq... | 04/17/2007 |
| 7189543 | Method for producing cadaverine dicarboxylate Cadaverine dicarboxylate is produced by performing an enzymatic decarboxylation reaction of a lysine solution while adding a dicarboxylic acid containing 4 to 10 carbons to the lysine solution to maintain pH of the solution at a level sufficient for the enzymatic de... | 03/13/2007 |
| 7129217 | Aqueous acrylamide solution containing saccharide This invention provides an aqueous solution of acrylamide that is useful as a starting material for high-quality polyacrylamide. Starting materials for polyacrylamide are an aqueous solution of acrylamide containing a saccharide and an aqueous solution of acrylamide... | 10/31/2006 |
| 7129059 | Process for the preparation of compounds with enhanced optical purity A process for preparation of a compound with enhanced optical purity is disclosed wherein a mixture of the enantiomers of a chiral amine is brought into contact with an enzyme having peptide deformylase activity with a bivalent metal ion as a cofactor. ... | 10/31/2006 |
| 7112665 | Genetically engineered plant cells and plants exhibiting resistance to glutamine synthetase inhibitors, DNA fragments and recombinants for use in the production of said cells and plants The invention relates to a DNA fragment containing a determined gene, the expression of which inhibits the antibiotic and herbicidal effects of Bialaphos and related products. It also relates to recombinant vectors, containing such DNA fragment, which enable ... | 09/26/2006 |
| 7105470 | Herbicidal compositions for tolerant or resistant soybean crops Herbicide combinations (A)+(B), if appropriate in the presence of safeners, with an effective content of (A) broad-spectrum herbicides from the group (A1) glufosinate (salts) and related compounds (A2) glyphosate (s... | 09/12/2006 |
| 7105322 | Process for the preparation of amides A novel biotechnological process for the preparation of nitriles, starting from amides, is described. Micro-organisms of the genus Amycolatopsis, Actinomadura or Rhodococcus are employed for this process. ... | 09/12/2006 |
| 7078199 | Method of manufacturing compound with biocatalyst by using controlled reaction temperature Provided is a method for producing a compound using a biocatalyst. In the method for continuously producing a compound using a biocatalyst in one or a plurality of reaction tanks, the downstream reaction temperature is set higher than the upstream reaction temperatu... | 07/18/2006 |
| 7064248 | Method of preparing fertile transgenic corn plants by microprojectile bombardment A method of preparing fertile transgenic Zea mays (corn) plants which stably express DNA encoding a Bacillus thuringiensis endotoxin, so as to impart insect resistance to the fertile transgenic plants is taught. The method comprises bombarding regenera... | 06/20/2006 |
| 7056707 | Bioactive compound and its isolation and method of treatment for lipoxygenase inhibition and as free radical scavenging agent The present invention relates to a novel compound having a molecular formula C13H15NO5 having molecular structure of Formula I and a process for the isolation of said compound. The present invention also relates to a method of inhibi... | 06/06/2006 |
| 7049107 | Method of producing phosphatidylserine A novel method of producing PS is described herein. The method first involves producing PLD enzyme through the use of enzyme-producing microorganisms. The PLD enzyme is reacted with a lecithin and source of serine to produce the phosphatidylserine (PS). The method d... | 05/23/2006 |
| 7018817 | Process for the preparation of compounds with enhanced optical purity Process for the preparation of a compound with enhanced optical purity wherein a mixture of the enantiomers of a chiral compound of formula 1 wherein: R1 represents an alkyl or an aryl group... | 03/28/2006 |
| 7015309 | Pyrrhocoricin-derived peptides, and methods of use thereof Modifications of the peptide pyrrhocoricin permit the production of a variety of anti-bacterial or anti-fungal peptides having general formula R1-Asp-Lys-Gly-X-Y-Leu-Pro-Arg-Pro-Thr-Pro-Pro-Arg-Pro-Ile-Tyr-X′-Y′-R2 SEQ ID NO: 1 or multimeri... | 03/21/2006 |
