Did You Know...
...that when IBM conducted a market study of Chester Carlson's invention in 1959, the company concluded that it would take only 5000 units of his new product to saturate the market? IBM therefore declined to be part of the new product introduction. Too bad for IBM. Carlson's invention was the xerography process, and his new product was the beginning of the Xerox Corporation. It is estimated that every day, worldwide, 3,000,000,000 copies are made!!
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| Number | Title | Issue Date |
| 8440433 | enhanced expression of moaA gene encoding molybdenum cofactor biosynthesis enzyme A and method for producing L-lysine using the same The present invention relates to a microorganism of Corynebacterium ssp. having enhanced expression of gene for encoding molybdenum cofactor biosynthesis enzyme A and a method for producing L-lysine using the same, which has effects on providing the productio... | 05/14/2013 |
| 8361758 | Microorganism of genus having resistance to kanamycin and enhanced L-lysine productivity and method of producing L-lysine using the same Provided are a microorganism of Corynebacterium genus capable of producing L-lysine and resistant to kanamycin, and a method of producing L-lysine using the same. ... | 01/29/2013 |
| 8329434 | Enhanced promoter and method for producing L-lysine using the same The present invention provides a nucleic acid molecule having enhanced promoter activity, which is operably linked to a gene encoding aspartate aminotransferase and derived from Corynebacterium glutamicum, a vector comprising the nucleic acid molecule, a tran... | 12/11/2012 |
| 8323933 | Vector for transformation using transposons, microorganisms transformed by the vector, and method for producing L-lysine using the same The present invention relates to a vector for transformation using transposon genes, microorganisms transformed by the vector, and a method for producing L-lysine using the microorganisms. ... | 12/04/2012 |
| 8268597 | Recombinant microorganism and method for producing L-lysine The present invention provides methods of producing L-lysine at a high yield using an Escherichia bacterium, especially E. coli, comprising a wild type or variant dapA gene of B. subtilis. The invention also provides related recombinant Esche... | 09/18/2012 |
| 8158390 | Method for the fermentative production of L-valine and suitable microorganism The invention relates to a method for producing L-valine and to a suitable microorganism. The inventive method is characterized by preferably enhancing the transaminase C activity of a coryneform bacterium, especially Corynebacterium glutamicum. The or... | 04/17/2012 |
| 8143032 | Alleles of the thrA gene of Enterobacteriaceae Alleles of the thrA gene from Enterobacteriaceae encoding desensitized aspartokinase I-homoserine dehydrogenase I enzymes and methods for the fermentative production of L-threonine using bacteria containing these alleles. ... | 03/27/2012 |
| 8137939 | Method of recovering L-threonine from L-threonine fermentation broth using nonsolvent Provided are a method of recovering L-threonine from the fermentation broth of an L-threonine producing microorganism, comprising: separating microbial bodies from the L-threonine containing fermentation broth obtained by culturing an L-threonine producing microorga... | 03/20/2012 |
| 8101386 | Escherichia coli strains which over-produce L-threonine and processes for the production of L-threonine by fermentation The present invention relates to the fields of microbiology and microbial genetics. More specifically, the invention relates to novel bacteria strains and processes employing these strains for the fermentative production of amino acids such as threonine. ... | 01/24/2012 |
| 8062869 | Method for producing L-lysine An Escherichia bacterium having dihydrodipicolinate synthase and aspartokinase, both of which are desensitized to feedback inhibition by L-lysine. The intracellular activity of dihydrodipicolinate reductase in this bacterium can also be enhanced. Furthermore,... | 11/22/2011 |
| 8058036 | Microorganism of genus having enhanced L-lysine productivity and a method of producing L-lysine using the same The present invention relates to a microorganism of Corynebacterium genus having enhanced L-lysine productivity and a method of producing L-lysine using the same. More particularly, the present invention relates to a recombinant microorganism of Corynebact... | 11/15/2011 |
| 8048651 | Methods for the preparation of lysine by fermentation of The present invention features methods of increasing the production of a fine chemical, e.g., lysine from a microorganism, e.g., Corynebacterium by way of deregulating an enzyme encoding gene, i.e., fructose-1,6-bisphosphatase. In a preferred embodiment, the ... | 11/01/2011 |
| 8048649 | Production of amino acids from sucrose in Methods and compositions for increased production of amino acids from C. glutamicum using sucrose as a carbon source are described. In one aspect, increased production of L-lysine from C. glutamicum is accomplished by using a strain having a mutation i... | 11/01/2011 |
| 8048650 | Microorganism of genus having enhanced L-lysine productivity and a method of producing L-lysine using the same The present invention relates to a microorganism of Corynebacterium genus having enhanced L-lysine productivity and a method of producing L-lysine using the same. More particularly, the present invention relates to a recombinant microorganism of Corynebact... | 11/01/2011 |
| 8030036 | Method for producing L-lysine or L-threonine A bacterium belonging to the genus Escherichia which has an ability to produce L-lysine or L-threonine and which is modified so that a malic enzyme does not function normally in a cell, and a method for producing L-lysine or L-threonine, comprising culturing ... | 10/04/2011 |
| 8017363 | Method for production of L-lysine using methanol-utilizing bacterium A method for production of L-lysine is provided which includes the steps of cultivating a methanol-utilizing bacterium in a culture medium to produce and accumulate L-lysine in the culture medium and collecting the L-lysine from the culture medium, wherein the metha... | 09/13/2011 |
| 7993885 | Method for producing L-lysine or L-arginine by using methanol assimilating bacterium A DNA encoding a variant of a protein having a loop region and six hydrophobic helixes which is involved in excretion of L-lysine to outside of a cell is described, wherein the DNA encodes a mutant protein which does not contain the loop region that is present in th... | 08/09/2011 |
| 7981640 | L-lysine-producing corynebacteria and process for the preparation of L-lysine L-lysine-producing strains of corynebacteria with enhanced lysE gene (lysine export carrier gene), in which strains additional genes chosen from the group comprising the dapA gene (dihydrodipicolinate synthase gene), the lysC gene (aspartate kinase gene), the... | 07/19/2011 |
| 7915018 | Method for producing L-amino acids using bacteria of the Enterobacteriaceae family There is disclosed a method for producing L-amino acid, for example L-threonine, L-lysine, L-histidine, L-phenylalanine, L-arginine or L-glutamic acid, using a bacterium of the Enterobacteriaceae family, wherein the bacterium has been modified to enhance an activity... | 03/29/2011 |
| 7888079 | Nε-acyl-L-lysine-specific aminoacylase The present invention provides an aminoacylase having superior abilities in specifically acylating and hydrolyzing e-amino group of Lys, and a method of producing Nε-acyl-L-lysine. The present invention provides Nε-acyl-L-lysine-specific aminoacylase containing th... | 02/15/2011 |
| 7883878 | Dry granulated product containing L-lysine as main component Hydrochloric acid, sulfuric acid or an L-lysine solution having an equivalent ratio of anion/L-lysine higher than 0.95 is added to a raw material L-lysine solution having an equivalent ratio of anion/L-lysine lower than 0.68 to adjust the equivalent ratio of anion/L... | 02/08/2011 |
| 7833762 | Method for producing L-amino acid An L-amino acid is produced by culturing an L-amino acid-producing bacterium which belongs to the Enterobacteriaceae family and which has been modified so that the acetyl-CoA synthetase activity is increased. ... | 11/16/2010 |
| 7807420 | Method for recovering a basic amino acid from a fermentation liquor The invention relates to a method for recovering a basic amino acid from the fermentation liquor of a micro-organism strain that produces the basic amino acid. The method comprises the following steps: a) isolation of the micro-organisms from the fermentation liquor... | 10/05/2010 |
| 7794990 | Microorganism of corynebacterium genus having enhanced L-lysine production ability and method of producing L-lysine using the same Provided are a microorganism of Corynebacterium genus that has an inactivated endogenous NCgl1835 gene therein and produces L-lysine, and a method of producing L-lysine using the same. ... | 09/14/2010 |
| 7771976 | Method for producing a non-aromatic L-amino acid using a bacterium of the family having expression of the csrA gene attenuated The present invention provides a method for producing a non-aromatic L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to the genus Escherichia or Pantoea, which has been modified to attenuate expressio... | 08/10/2010 |
| 7723081 | Bacteria containing aspartate-semialdehyde dehydrogenase, phosphoenolpyruvate carboxylase, and transhydrogenase to produce L-lysine in , and methods of using same An Escherichia bacterium (1) which harbors dihydrodipicolinate synthase of which feedback inhibition by L-lysine is desensitized and aspartokinase of which feedback inhibition by L-lysine is desensitized, (2) in which intracellular activity of dihydrodipicoli... | 05/25/2010 |
| 7666634 | Fermentation process for the preparation of L-amino acid using modified wherein the ytfP-yjfA gene region is inactivated The present invention relates to a fermentation process for the preparation of L-amino acids in which the following steps are carried out: (a) fermentation of the microorganisms of the family Enterobacteriaceae producing the desired L-amino acid, in which microorgan... | 02/23/2010 |
| 7638313 | Processes for the fermentative preparation of L-threonine using strains of in which the gene is inactivated The invention relates to a process for the preparation of L-amino acids, in particular L-threonine, in which the following steps are carried out: a) fermentation of microorganisms of the Enterobacteriaceae family which produce the desired L-amino acid and in which t... | 12/29/2009 |
| 7566553 | Microorganism of Sp, or Sp, comprising foreign NADP dependent glyceraldehyde-3-phosphate dehydrogenase gene and method for producing L-lysine using the same Provided are an Escherichia species microorganism and Corynebacterium species microorganism that are transformed with a foreign NADP dependent glyceraldehydes-3-phosphate dehydrogenase gene and have the ability to produce L-lysine and a method of produ... | 07/28/2009 |
| 7524657 | Alleles of the sigA gene from coryneform bacteria The invention relates to alleles of the sigA gene from coryneform bacteria which code for sigma factors A and a process for the fermentative preparation of L-lysine using bacteria which contain these alleles. ... | 04/28/2009 |
| 7452701 | Methods for the preparation of β-amino acids Purified β-amino acids are of considerable interest in the preparation of pharmacologically active compounds and industrial precursors. Although enantiomerically pure β-amino acids can be produced by standard chemical synthesis, this traditional approach is time c... | 11/18/2008 |
| 7442530 | Process for the production of L-amino acids using strains of the Enterobacteriaceae family which contain an enhanced fadR or iclR gene This invention relates to a process for the production of L-amino acids, in particular L-threonine, in which the following steps are performed: a) fermentation of microorganisms of the Enterobacteriaceae family which produce the desired L-amino acid, in which at lea... | 10/28/2008 |
| 7432085 | Method for producing L-amino acid In a method for producing an L-amino acid by culturing a microorganism having an ability to produce an L-amino acid in a medium to produce and accumulate the L-amino acid in the medium and collecting the L-amino acid from the medium, a Gram-negative bacterium having... | 10/07/2008 |
| 7416740 | Dry granulated product containing L-lysine as main component Hydrochloric acid, sulfuric acid or an L-lysine solution having an equivalent ratio of anion/L-lysine higher than 0.95 is added to a raw material L-lysine solution having an equivalent ratio of anion/L-lysine lower than 0.68 to adjust the equivalent ratio of anion/L... | 08/26/2008 |
| 7399617 | Method for producing an L-amino acid in an bacterium via altering expression levels of target proteins A bacterium belonging to the genus Escherichia which has an ability to produce an L-amino acid, wherein the ability to produce the L-amino acid is increased by increasing expression of an L-amino acid excretion protein is described. A method for producing the... | 07/15/2008 |
| 7381548 | Method for producing L-amino acid using bacterium of family having expression of gene attenuated The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus Escherichia or Pantoea, which has been modified to attenuate expression of the yafA ge... | 06/03/2008 |
| 7368266 | Method for L-threonine production A method for producing L-threonine using a microorganism is provided. In the method, additional one or more copies of each of the phosphoenolpyruvate carboxylase (ppc) gene and the threonine operon are integrated into a particular site of the chromosomal DNA of a mi... | 05/06/2008 |
| 7368276 | Polynucleotide constructs encoding aspartate kinase, aspartate-semialdehyde dehydrogenase, and dihydrodipicolinate reductase and related constructs, products, and methods The invention relates to production of lysine, and provides several isolated polynucleotide molecules useful for the production of L-lysine. One such polynucleotide encodes an aspartate kinase (ask), an aspartate-semialdehyde dehydrogenase (asd) and a dihydrodipicol... | 05/06/2008 |
| 7354745 | Method for producing L-β-lysine Purified β-amino acids are of considerable interest in the preparation of pharmacologically active compounds. Although enantiomerically pure β-amino acids, such as L-β-lysine, can be produced by standard chemical synthesis, this traditional approach is time consu... | 04/08/2008 |
| 7335506 | Method for producing L-lysine or L-arginine by using methanol-assimilating bacterium A DNA encoding a variant of a protein, the protein having a loop region and six hydrophobic helices and involved in secretion of L-lysine to the outside of a cell, wherein the DNA encodes a variant of a protein not containing the loop region and facilitates secretio... | 02/26/2008 |
