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| Number | Title | Issue Date |
| 8114638 | Arabinitol dehydrogenase from Stable and active arabinitol dehydrogenases (LAD) from Neurospora crassa and mutants thereof are disclosed. Arabinitol dehydrogenases are useful in the production of xylitol and ethanol from an arabinose containing substrate. Recombinant and heterologously ex... | 02/14/2012 |
| 8012721 | Method for glucose production using endoglucanase core protein for improved recovery and reuse of enzyme The present invention pertains to a method of converting cellulose to glucose by treating a pretreated lignocellulosic substrate with an enzyme mixture comprising cellulase enzyme and endoglucanase core proteins, wherein the endoglucanase core proteins are present i... | 09/06/2011 |
| 7998711 | Variant CBH1.1 Disclosed are variants of Humicola grisea Cel7A (CBH1.1), H. jecorina CBH1 variant or S. thermophilium CBH1, nucleic acids encoding the same and methods for producing the same. The variant cellulases have the amino acid sequence of a glycosyl hy... | 08/16/2011 |
| 7993884 | Beta-xylosidase for conversion of plant cell wall carbohydrates to simple sugars Xylose-containing plant material may be hydrolyzed to xylose using a β-D-xylosidase which exhibits unexpectedly high activity. The enzyme has a kcat value for catalysis of approximately 185 sec−1 for 1,4-β-D-xylobiose (X2) when measured at ... | 08/09/2011 |
| 7960149 | Polypeptides having beta-glucosidase activity and polynucleotides encoding same The present invention relates to isolated polypeptides having beta-glucosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as m... | 06/14/2011 |
| 7927842 | Method of preparing 2-deoxyribose 5-phosphate The present invention discloses a method of preparing 2-deoxyribose 5-phosphate by reacting glyceraldehyde 3-phosphate and acetaldehyde in the presence of either a microorganism itself which contains 2-deoxyribose-5-phosphate aldolase but substantially no phosphatas... | 04/19/2011 |
| 7927843 | Method of preparing 2-deoxyribose 5-phosphate The present invention discloses a method of preparing 2-deoxyribose 5-phosphate by reacting glyceraldehyde 3-phosphate and acetaldehyde in the presence of either a microorganism itself which contains 2-deoxyribose-5-phosphate aldolase but substantially no phosphates... | 04/19/2011 |
| 7915017 | Process for the treatment of lignocellulosic biomass A process for the treatment of biomass to render structural carbohydrates more accessible and/or digestible using concentrated ammonium hydroxide with or without anhydrous ammonia addition, is described. The process preferably uses steam to strip ammonia from the bi... | 03/29/2011 |
| 7820414 | Xylitol dehydrogenase-inactivated and arabinose reductase-inhibited mutant of , method of producing high-yield of xylitol using the same, and xylitol produced thereby Disclosed herein are Xylitol dehydrogenase-inactivated and arabinose reductase-inhibited mutant of Candida tropicalis, a method of producing a high yield of xylitol using the same, and xylitol produced by the method. More specifically, disclosed are a method ... | 10/26/2010 |
| 7767425 | Enzymatic synthesis of sugar acrylates A process is described for the enzymatic synthesis of sugar acrylates, and a process is described for preparing polymeric sugar acrylates, the polymers obtainable by this process and their use for preparing, for example, cosmetics, drugs, laundry detergents, thicken... | 08/03/2010 |
| 7670813 | Inorganic salt recovery during processing of lignocellulosic feedstocks A method for recovering inorganic salt during processing of a lignocellulosic feedstock is provided. The method comprises pretreating the lignocellulosic feedstock by adding an acid or a base to the feedstock to produce a pretreated lignocellulosic feedstock. A solu... | 03/02/2010 |
| 7608436 | Process for producing saccharide oligomers A process for preparing saccharide oligomers uses an aqueous feed composition that comprises at least one monosaccharide or linear saccharide oligomer, and has a solids concentration of at least about 70% by weight. The feed composition is heated to a temperature of... | 10/27/2009 |
| 7592163 | Highly active xylose reductase from A new xylose reductase encoding gene from Neurspora crassa was heterologously expressed in E. coli as a His-tag fusion protein and subsequently purified in high yield. This xylose reductase was shown to have a high turnover rate and catalytic efficienc... | 09/22/2009 |
| 7501267 | Gene sequence of L-rhamnose isomerase having new catalytic function and use thereof In the rare sugar strategy of Izumoring (FIG. 1), it is intended to establish a reaction system of producing rare sugars of many types by acquiring an isomerase which acts on various rare aldoses and, therefore, is most efficient in producing various rare ket... | 03/10/2009 |
| 7435564 | Production of invert syrup from sugarcane juice using immobilized invertase This invention is directed to a novel process in which raw sugarcane juice is first refined through a number of steps and then bioenzymatically converted into refined invert syrup or glucose-fructose concentrated solution using a reactor packed with immobilized inve... | 10/14/2008 |
| 7419809 | Method for glucose production with a modified cellulase mixture The present invention pertains to a method of converting cellulose to glucose by treating a pretreated lignocellulosic substrate with an enzyme mixture comprising cellulase enzyme and a modified CBHO, wherein the modified CBHI is present in the enzyme mixture at an ... | 09/02/2008 |
| 7413882 | Methods for degrading or converting plant cell wall polysaccharides The present invention relates to methods for converting plant cell wall polysaccharides into one or more products, comprising: treating the plant cell wall polysaccharides with an effective amount of a spent whole fermentation broth of a recombinant microorganism, w... | 08/19/2008 |
| 7385185 | Molecular activation for tandem mass spectroscopy In a tandem mass spectrometer means are provided for molecular activation of ions prior to fragmentation. An embodiment of a tandem mass spectrometer comprises a first collision cell receiving analyte ions having an internal energy and a second collision cell situat... | 06/10/2008 |
| 7361806 | Transgenic plants expressing a cellulase The instant disclosure describes the application of genetic engineering techniques to produce cellulase in plants. Cellulase coding sequences operably linked to promoters active in plants may be transformed into the nuclear genome and/or the plastid genome of a plan... | 04/22/2008 |
| 7354743 | Methods for degrading lignocellulosic materials The present invention relates to methods for degrading a lignocellulosic material, comprising: treating the lignocellulosic material with an effective amount of one or more cellulolytic enzymes in the presence of at least one surfactant selected from the group consi... | 04/08/2008 |
| 7351408 | Glycoconjugates and methods Methods for making the functionalized glycoconjugates include (a) contacting a cell with a first monosaccharide, and (b) incubating the cell under conditions whereby the cell (i) internalizes the first monosaccharide, (ii) biochemically processes the first monosacch... | 04/01/2008 |
| 7326770 | fucosyltransferases This invention provides nucleic acid and amino acid sequences of fucosyltransferases from Helicobactor pylori. The invention also provides methods to use the fucosyltransferases to synthesize oligosaccharides, glycoproteins, and glycolipids. ... | 02/05/2008 |
| 7314746 | Apparatus and method for preparative scale purification of nucleic acids Apparatus and methods are described for pharmaceutical grade manufacture extrachromosomal nucleic acids from cell lysates using flotation to separate and eliminate undesired insoluble cellular debris including chromosomal DNA from the lysates. A gas is introduced to... | 01/01/2008 |
| 7314528 | Crystallization of sugars The invention relates to removing crystallization inhibitors from a solution comprising one or more reducing sugars by nanofiltration, hydrolysis and/or chromatography. The reducing sugars are typically selected from fructose and xylose. ... | 01/01/2008 |
| 7312055 | Hybrid enzymes The present invention relates to a hybrid enzyme comprising at least one carbohydrate-binding module amino acid sequence and at least the catalytic module of a glucoamylase amino acid sequence. The invention also relates to the use of the hybrid enzyme in starch pro... | 12/25/2007 |
| 7304031 | Methods and means for producing proteins with predetermined post-translational modifications Described are methods for identifying, selecting, and obtaining mammalian cells capable of producing proteinaceous molecules having predetermined post-translational modifications, wherein the post-translational modifications are brought about by the mammalian cell i... | 12/04/2007 |
| 7304039 | Glucose-based compounds with affinity to P-selectin The present invention relates to certain glucose-based compounds that have an affinity to P-selectin. Further, the invention relates to the use of these glucose-based compounds for the preparation of pharmaceutical compositions for the treatment of disorders associa... | 12/04/2007 |
| 7303899 | Expression of granular starch hydrolyzing enzymes in and process for producing glucose from granular starch substrates The present invention relates to filamentous fungal host cells and particularly Trichoderma host cells useful for the production of heterologous granular starch hydrolyzing enzymes having glucoamylase activity (GSHE). Further the invention relates to a method... | 12/04/2007 |
| 7270992 | Method of preparing 2-deoxyribose 5-phosphate The present invention discloses a method of preparing 2-deoxyribose 5-phosphate by reacting glyceraldehyde 3-phosphate and acetaldehyde in the presence of either a microorganism itself which contains 2-deoxyribose-5-phosphate aldolase but substantially no phosphatas... | 09/18/2007 |
| 7268273 | Recovering metals from soil The invention relates to recovering metals, such as nickel and cobalt, by phytomining or phytoextracting soils rich in metals wherein the desired metal is selectively accumulated in hyperaccumulator plants by adjusting the soil pH. The metals are ultimately recovere... | 09/11/2007 |
| 7264962 | Enzymatic cascade bioreactor Disclosed is an apparatus and method for continuously converting sucrose to β-D-glucose. The method comprises a three stage enzymatic reactor in which an aqueous solution of sucrose is first converted into a solution of fructose and α-D-glucose by passing it throu... | 09/04/2007 |
| 7256047 | Measurement of gluconeogenesis and intermediary metabolism using stable isotopes The present invention provides a combination of carbon-13 and deuterium metabolic tracers and methods that when used in conjunction with nuclear magnetic resonance spectroscopy, provide a measurement of metabolic fluxes in the target organisms. The tracers of the pr... | 08/14/2007 |
| 7247458 | Enzymatic decarboxylation of 2-keto-L-gulonic acid to produce xylose The invention is drawn to the enzymatic decarboxylation of 2-keto-L-gulonic acid (2-KLG) to produce xylose. The invention is also drawn to a method to detect xylose in vitro or in vivo (intracellularly), which employs an L-xylose dehydrogenase. ... | 07/24/2007 |
| 7241587 | Method of uncoupling the catabolic pathway of glycolysis from the oxidative membrane bound pathway of glucose conversion The invention provides methods for producing products comprising improved host cells genetically engineered to have uncoupled productive and catabolic pathways. In particular, the present invention provides host cells having a modification in nucleic acid encoding a... | 07/10/2007 |
| 7226761 | Manufacture of five-carbon sugars and sugar alcohols The invention relates to the methods of manufacturing five-carbon sugars and sugar alcohols as well as other compounds derived from pentose-phosphate pathway from readily available substrates such a hexoses using metabolically engineered microbial hosts. ... | 06/05/2007 |
| 7220565 | Polypeptides having cellobiohydrolase activity and polynucleotides encoding same The present invention relates to isolated polypeptides having cellobiohydrolase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as ... | 05/22/2007 |
| 7205141 | Gene sequence of L-rhamnose isomerase having new catalytic function and use thereof In the rare sugar strategy of Izumoring (FIG. 1), it is intended to establish a reaction system of producing rare sugars of many types by acquiring an isomerase which acts on various rare aldoses and, therefore, is most efficient in producing variou... | 04/17/2007 |
| 7202063 | Processes for the production of rhamnolipids A process for producing rhamnolipids involving culturing Pseudomonas chlororaphis strain NRRL B-30761 in a first aqueous culture medium containing about 0.3% NH4H2PO4, about 0.2% K2HPO4, about 0.2% carbon... | 04/10/2007 |
| 7198925 | Pre-treatment of bales of feedstock The present invention is directed to a method of pre-treating a lignocellulosic feedstock. The lignocellulosic feedstock comprises cereal straw, stover, or grass. One or more than one bale of lignocellulosic feedstock is conveyed into a pre-treatment reactor. Steam ... | 04/03/2007 |
| 7160856 | α-O-linked glycoconjugates, methods of preparation and uses thereof The present invention provides novel α-O-linked glycoconjugates such as α-O-linked glycopeptides, as well convergent methods for synthesis thereof. The general preparative approach is exemplified by the synthesis of the mucin motif commonly found on epithelial tum... | 01/09/2007 |
