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Class 424/93.2 - Genetically modified micro-organism, cell, or virus (e.g., transformed, fused, hybrid, etc.)


Subclass of Class 424 - Drug, bio-affecting and body treating compositions
Definition: Subject matter involving a micro-organism, cell or virus
No. of patents: 1761
Last issue date: 05/29/2012


                  44    
NumberTitleIssue Date
5219740Retroviral gene transfer into diploid fibroblasts for gene therapy
A process of mammalian gene therapy. Explanted fibroblasts are genetically modified by introducing a retroviral construct containing a nucleotide sequence encoding for a therapeutic substance. The genetically modified fibroblasts are implanted into a mamm...
06/15/1993
5212296Expression of herbicide metabolizing cytochromes
DNA sequences encoding herbicide metabolizing cytochrome P450 enzymes and iron-sulfur proteins that donate electrons to these enzymes, were introduced into plants and microorganisms rendering them able to produce the encoded gene products and to metaboliz...
05/18/1993
5186934Bacillus thuringiensis gene encoding a coleopteran-active toxin
A novel B.t. gene encoding a toxin which is toxic to coleopteran insects has been cloned from a coleopteran-active B. thurningiensis microbe. The DNA encoding the B.t. toxin can be used to transform various prokaryotic and eukaryotic microbes to express t...
02/16/1993
5180581Biological insect control agents and methods of use
Insect control agents comprising a This invention was made with funding from the National Institutes of Health (Grant No. AI-23719) and with Hatch Act funding from the U.S. Department of Agriculture (Grant No. GE000918). The U.S. government may have certain ...
01/19/1993
5157207Modified plant containing a bacterial insculant
A method for the production of a plant of reduced stature is provided comprising the introduction of a bacterial cell into a seed or a plant, the bacterial cell being capable of replicating in the plant and of inducing a reduction in plant stature. A seed...
10/20/1992
5151363Isolates of Bacillus thuringiensis that are active against nematodes
The invention concerns novel isolates of Bacillus thuringiensis (B.t.) which contain a toxin(s) which is active against nematodes. This B.t. toxin(s) or B.t. isolate(s) can be used to treat animals and plants hosting susceptible nematodes....
09/29/1992
5147640Strains of Bacillus thuringiensis insecticidal compositions containing the same
The present invention provides novel strains of Bacillus thuringiensis containing genes that code for P1 endotoxin proteins. The invention also provides methods and compositions for controlling insects or protecting plants from insect attack with a novel ...
09/15/1992
5133962Method of controlling coleopteran insects with Bacillus thuringiensis
A novel B.t. toxin gene encoding a protein toxic to coleopteran insects has been cloned from a novel coleopteran-active B. thuringiensis microbe. The DNA encoding the B.t. toxin can be used to transform various prokaryotic and eukaryotic microbes to expre...
07/28/1992
5128130Hybrid Bacillus thuringiensis gene, plasmid and transformed Pseudomonas fluorescens
A novel hybrid B.t. toxin gene toxic to lepidopteran insects has been cloned. The DNA encoding the B.t. toxin can be used to transform various prokaryotic and eukaryotic microbes to express the B.t. toxin. These recombinant microbes can be used to control...
07/07/1992
5126133Bacillus thuringiensis isolate active against lepidopteran pests, and genes encoding novel lepidopteran-active toxins
Novel Bacillus thuringiensis genes encoding toxins which are active against lepidopteran insects have been cloned from novel lepidopteran-active B. thuringiensis microbes. The DNA encoding the B. thuringiensis toxins can be used to transform various proka...
06/30/1992
5098706Juvenile hormone esterase for insect control
A method of controlling insects comprises administering juvenile hormone esterase during a larval stadium to disrupt normal development. The juvenile hormone esterase is preferably administered by infecting insects with a baculovirus including the gene fo...
03/24/1992
5080897Novel bacillus thuringiensis strains, and related insecticidal compositions
The present invention relates to novel Bacillus thuringiensis transconjugant strains having improved insecticidal activity. The novel strains are produced by a combination of plasmid curing and conjugation of active strains....
01/14/1992
5064648Use of Bacillus thuringiensis microbe for controlling lesser mealworm, Alphitobius diaperinus
The subject invention concerns the use of a novel and useful bioinsecticide against the lesser mealworm (Alphitobius diaperinus). The lesser mealworm is a devasting pest in the poultry industry. The bioinsecticide of the subject invention is a novel B. th...
11/12/1991
5063055Preparation of strains of Bacillus thuringiensis having an improved activity against certain lepidopterous pests and novel strain produced thereby
The invention relates to a strain of Bacillus thuringiensis, GC 91, a sample of which has been deposited under the accession number NCTC 118921, or a derivative or mutant thereof having entomocidal activity against lepidopterous pests. The invention also ...
11/05/1991
5055294Chimeric Bacillus thuringiensis crystal protein gene comprising HD-73 and Berliner 1715 toxin genes, transformed and expressed in Pseudomonas fluorescens
A novel hybrid B.t. toxin gene toxic to lepidopteran insects has been cloned. The DNA encoding the B.t. toxin can be used to transform various prokaryotic and eukaryotic microbes to express the B.t. toxin. These recombinant microbes can be used to control...
10/08/1991
5039523Novel Bacillus thuringiensis isolate denoted B.t. PS81F, active against lepidopteran pests, and a gene encoding a lepidopteran-active toxin
A novel B.t. toxin gene encoding a protein toxic to lepidopteran insects has been cloned from a novel lepidopteran-active B. thuringiensis microbe. The DNA encoding the B.t. toxin can be used to transform various prokaryotic and eukaryotic microbes to exp...
08/13/1991
5024837Coleopteran active microorganisms, related insecticide compositions and methods for their production and use
This invention relates to Bacillus thuringiensis strains that have insecticidal activity against lepidopteran and coleopteran insects, the coleopteran-active endotoxin being produced by an acquired plasmid. This invention also relates to the crystalline p...
06/18/1991
5019501Process for the activation of promoters of bacteria
A process for the activation of genes in micro-organisms, in which genes not occurring as such in nature are activated by contact with plants or with the substance or substances causing the activation and present or not in plant fragments or plant exudate...
05/28/1991
5008194nifH promoters of Bradyrhizobium
The nifH promoter regions of Bradyrhizobium japonicum and Bradyrhizobium sp. (parasponia) have been sequenced and found to be significantly homologous. Recombinant DNA molecules comprising foreign genes under the control of such promoters are provided. Rh...
04/16/1991
5002765Cloning and expression of bacillus thuringiensis gene toxic to beetles of the order coleoptera
The toxin gene encoding a protein toxic to beetles of the order Coleoptera, named M-7, has been cloned and expressed. M-7 is a novel Bacillus thuringiensis strain which has been deposited with a recognized culture repository. The microbe is now known as B...
03/26/1991
5001061nifD promoter of Bradyrhizobium
The nifD promoter regions of Bradyrhizobium japonicum and Bradyhizobium sp. (Parasponia) have been sequenced and found to be significantly homologous. Recombinant DNA molecules comprising foreign genes under the control of such promoters are provided. Rhi...
03/19/1991
4996155Bacillus thuringiensis gene encoding a coleopteran-active toxin
A novel B.t. toxin gene encoding a protein toxic to coleopteran insects has been cloned from a novel coleopteran-active B. thuringiensis microbe. The DNA encoding the B.t. toxin can be used to transform various prokaryotic and eukaryotic microbes to expre...
02/26/1991
4988586Method for the prevention of fusarium diseases and microorganisms used for the same
A method for the prevention of Fusarium diseases comprising the application of a microorganism that decomposes or detoxifies fusaric acid to the plant or to the soil. The microorganisms are the genuses Cladosporium and Pseudomonas that have the ability to...
01/29/1991
4980286In vivo introduction and expression of foreign genetic material in epithelial cells
Epithelial cells expressing foreign genetic material are described. The foreign genetic material can be DNA or RNA which does not occur in epithelial cells; DNA or RNA which occurs in epithelial cells but is not expressed in them at levels which are biolo...
12/25/1990
4940838Process for the incorporation of foreign dna into the genome of dicotyledonous plants
The invention relates to a process for the incorporation of foreign DNA into chromosomes of dicotyledonous plants by infecting the plants or incubating plant protoplasts with Agrobacterium bacteria, which contain one or more plasmids, wherein bacteria are...
07/10/1990
4877438Microbial and chemical control of fruit russetting
A method is provided of reducing fruit russetting by treating the surface of a fruit to reduce the amount of auxins present on the surface. In a preferred embodiment, the population of auxin-producing bacteria is reduced by providing a competing auxin-def...
10/31/1989
4866042Method for the delivery of genetic material across the blood brain barrier
A method for treating genetic and acquired brain disorders is disclosed in which genetic material is introduced into the blood stream for delivery to the brain. Prior to delivery, the interendothelial structure of the BBB is chemically altered to permit p...
09/12/1989
4851340Strains of Bacillus toxic to Coleoptera
The present invention provides a new strain of micro-organism, Bacillus thuringiensis of pathotype C, a process for obtaining a toxin therefrom and an insecticide for combating Coleoptera containing the new micro-organism or a toxin obtained therefrom....
07/25/1989
4803165Nif promoter of fast-growing rhizobium japonicum
The promoter of the nifH gene of the fast-growing Rhizobium japonicum strain USDA 191, has been cloned. Over 4.2 kilobase pairs (kbp) of DNA were sequences (FIG. 1). Sequences encoding nifH and the 5'-end of nifD were identified, as were sequences involve...
02/07/1989
4797279Insecticidal hybrid bacteria from b.t. kurstaki and b.t. tenebrionis
The invention provides hybrid microorganisms comprising the gene coding for b.t. kurstaki delta-endotoxin and the gene coding for b.t. tenebrionis delta-endotoxin, their preparation, insecticidal compositions comprising such microorganisms and their use....
01/10/1989
4766077Ice nucleation deficient microorganisms by genetic manipulation
Ice nucleation bacteria are modified in vitro to confer an ice nucleation deficient phenotype. Modification is accomplished by deletion, substitution, insertion, inversion, or transversion of a DNA segment within the gene locus responsible for the INA phe...
08/23/1988
4751081Chitinase-producing bacteria
Novel bacteria strains are described which are created by the introduction of DNA encoding for the production of chitinase, an enzyme capable of degrading chitin present in fungi and nematodes. The strains have utility in producing chitinase for the purpo...
06/14/1988
4749620Encapsulated active material system
Capsules are formed herein a liquified core while avoiding capsule core gelation by adding drops of a solution of either an anionic polymer composition or a cationic polymer composition to a solution of an ionic polymer of opposite charge. The drops conta...
06/07/1988
4695455Cellular encapsulation of pesticides produced by expression of heterologous genes
Methods and compositions are provided for preparing and using pesticides, where the pesticides are encapsulated in non-proliferating cells. The methods involve introducing a heterologous gene into a cellular host, where expression of the heterologous gene...
09/22/1987
4584274Bacteriophage-resistant plant growth promoting rhizobacteria
Bacteriophage-resistant plant growth promoting rhizobacteria are employed for enhancing the yield of root crops, such as potatoes, sugar beets, radishes and the like, grown in soils which are infected by bacteriophage which limit the root colonization by ...
04/22/1986
4582799Process for recovering nonsecreted substances produced by cells
Disclosed is a process for recovering nonsecreted substances produced by cells. The process eliminates some of the high molecular weight contaminants thereby simplifying the purification process. The cells are encapsulated within a semipermeable membrane ...
04/15/1986
4409331Preparation of substances with encapsulated cells
Disclosed is a system and process for producing substances produced in cells such as antibodies and biological response modifiers. Cells which produce the substance of interest are encapsulated within semipermeable membranes having an upper limit of perme...
10/11/1983
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