Did You Know...
...that the Band-Aid Bandage was invented by a Johnson & Johnson employee whose wife had cut herself? Earl Dickson's wife was rather accident prone, so he set out to develop a bandage that she could apply without help. He placed a small piece of gauze in the center of a small piece of surgical tape, and what we know today as the Band Aid bandage was born!
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| Number | Title | Issue Date |
| 8173105 | Contrast agents and methods for preparing contrast agents Contrast agents comprising a scaffold protein having at least one operative integrated metal ion binding site. ... | 05/08/2012 |
| 7964557 | Inhibition of wet type age related macular degeneration (AMD) by adiponectin or acrp 30 The present invention provides new methods of treating wet type of age related macular degeneration by administering adiponectin (APN) or a functional fragment derived therefrom. One of the pathological complications of age related macular degeneration (AMD) is chor... | 06/21/2011 |
| 7927581 | Peptide-based multimeric targeted contrast agents Peptides and peptide-targeted multimeric contrast agents are described, as well as methods of making and using the contrast agents. ... | 04/19/2011 |
| 7906104 | Methods for detecting pancreatic beta-islet cells and diseases thereof The role of synaptic adhesion molecules in human cell development and function is largely unknown. This invention provides methods to study β-cell function in native tissue through the use of novel adhesion and migrations assays. Through the use of these assays, th... | 03/15/2011 |
| 7608248 | Stable isotope-labeled aromatic amino acids, method for incorporating the same in target protein and method for NMR-structural analysis of proteins The present invention herein provides, for instance, a stable isotope-labeled phenylalanine wherein a carbon atom of the phenyl group linked to an amino acid residue is 13C, 2 to 4 carbon atoms of the remaining 5 carbon atoms constituting the phenyl group... | 10/27/2009 |
| 7438890 | Binding peptides for carcinoembryonic antigen (CEA) The present invention provides binding moieties for CEA, which have a variety of uses wherever detecting, isolating or localizing CEA, and particularly CEA as opposed to cross-reactive antigens such as NCA, is advantageous. Particularly disclosed are synthetic, isol... | 10/21/2008 |
| 7429381 | Production and use of novel peptide-based agents for use with bi-specific antibodies The present invention relates to a bi-specific antibody or antibody fragment having at least one arm that is reactive against a targeted tissue and at least one other arm that is reactive against a linker moiety. The linker moiety encompasses a hapten to which antib... | 09/30/2008 |
| 7411042 | Tumor associated nucleic acids and uses therefor The invention describes SAGE (sdph3.10) and sdp3.5 tumor associated nucleic acids, including fragments and biologically functional variants thereof. Also included are polypeptides and fragments thereof encoded by such nucleic acid molecules, and antibodies relating ... | 08/12/2008 |
| 7402298 | EphA2 monoclonal antibodies and methods of making and using same The invention provides a monoclonal antibody, a fragment thereof, or a molecular complex thereof that binds to an extracellular domain of an EphA2 receptor molecule, wherein binding of the monoclonal antibody or fragment thereof to the EphA2 receptor molecule presen... | 07/22/2008 |
| 7387772 | Chimeric, human and humanized anti-CSAP monoclonal antibodies The present invention provides humanized, chimeric and human anti-CSAp antibodies and anti-CSAp antibody fusion proteins that are useful for the treatment and diagnosis of various cancers, including colon cancer. ... | 06/17/2008 |
| 7384794 | Micro-devices and analytical procedures for investigation of biological systems Fibres with an extraction phase coated thereon in combination with a positioning device are described to perform adsorption of components of interest from an animal or animal tissue for the investigation of living systems. A number of interfaces to analytical instru... | 06/10/2008 |
| 7371365 | Methods for detecting parenchymal plaques in vivo Methods for detecting parenchymal plaque deposits in the brain of a living mammal are described that include administering a polyamine modified, labeled polypeptide having specific binding affinity for the extracellular deposit, to the living mammal. Isolated β-amy... | 05/13/2008 |
| 7371738 | Method of transdermal drug delivery using hyaluronic acid nanoparticles The present invention relates to the development of a hyaluronic acid and hyaluronic acid hybrid nanoparticle systems for the administration of active molecules, peptides, DNA and/or other hydrophilic or hydrophobic molecules, the composition of hyaluronic acid and ... | 05/13/2008 |
| 7358226 | Ultrasonic concentration of drug delivery capsules Methods, compositions and apparatus for localized delivery of compounds are provided. In certain embodiments, radiation force is used to direct carriers to a target site, and additional radiation is used to fragment the localized carriers, releasing associate compou... | 04/15/2008 |
| 7354568 | Magnetic resonance imaging agents for the detection of physiological agents The invention relates to novel magnetic resonance imaging contrast agents and methods of detecting physiological signals or substances. ... | 04/08/2008 |
| 7335771 | Quinacridone derivatives as labelling reagents for fluorescence detection of biological materials Disclosed are new quinacridone dye derivatives having characteristic fluorescence lifetimes. Also disclosed are methods for labelling target biological materials employing the quinacridone dyes and use of the labelled materials in biological assays. The quinacridone... | 02/26/2008 |
| 7314615 | IκB Kinase-β (IKKβ) binding antibodies and methods of using same The present invention provides an isolated nucleic acid molecules encoding IκB kinase (IKK) catalytic subunit polypeptides, which are associated with an IKK serine protein kinase that phosphorylates a protein (IκB) that inhibits the activity of the NF-κB transcri... | 01/01/2008 |
| 7312461 | Laparoscopic tumor therapy using high energy electron irradiation A laparoscopic tumor therapy method and an articulated electron beam transport system are provided for use with a high power, long focus electron source for tumor therapy. The high power, long focus electron source generates an e-beam. The e-beam is transported thro... | 12/25/2007 |
| 7306807 | Hemorrhagic feline calicivirus, calicivirus vaccine and method for preventing calicivirus infection or disease The present invention relates to a novel, isolated and purified hemorrhagic feline calicivirus FCV-DD1. The invention further embraces monovalent and multivalent vaccines containing the new FCV-DD1 strain. In addition, the invention encompasses methods of protecting... | 12/11/2007 |
| 7285289 | Nanoparticle vaccines The present invention relates to nanoparticle vaccines comprised of a carrier, particularly polymerized lipids, having multiple copies of an antigen or combinations of different antigens displayed on the carrier. Such antigen-displaying nanoparticles may also displa... | 10/23/2007 |
| 7279150 | Chelating agents with lipophilic carriers Compounds useful for associating with nanoparticle or microparticle emulsions to obtain magnetic resonance images permit control of the relaxivity of the signal and readily associate with the particulate components. ... | 10/09/2007 |
| 7267941 | Cyanovirin variant-polymer conjugates The present invention provides variants of cyanovirin-N and water-soluble polymer conjugates thereof. The cyanovirin-N of the invention are particularly suited for site-selective covalent attachment of one or more water soluble polymers, to provide polymer conjugate... | 09/11/2007 |
| 7252959 | Assays for diagnosis of thrombophilic disease The present invention provides methods for diagnosing and/or monitoring thrombophilic disease in a patient that can result from the antiphospholipid antibody syndrome (aPL syndrome). The methods of the invention are premised on the inhibition of binding of an antico... | 08/07/2007 |
| 7232689 | Calibration procedure for investigating biological systems Use of calibrant in extraction phase is described for quantification of components of interest in samples in laboratory application as well as in on-site monitoring. This approach is particularly useful for in-vivo investigation of living systems. ... | 06/19/2007 |
| 7230115 | Preparation of compounds useful for the detection of hypoxia Novel 18F-flourine compounds useful for non-invasive imaging techniques such as PET, for detecting tissue hypoxia, and methods for preparing them are disclosed. Novel intermediate compounds and methods for preparing them are also disclosed. Diagnostic kit... | 06/12/2007 |
| 7229773 | Screening method for apoptosis-suppressing or-promoting substance To provide a screening method for an apoptosis-suppressing substance or an apoptosis-promoting substance, the application of which substances to pharmaceuticals or diagnostic drugs are expected, also to provide an apoptosis-suppressing substance or an apoptosis-prom... | 06/12/2007 |
| 7223282 | Remote activation of an implantable device The invention is directed to an implantable device, such as a stent, for delivering a therapeutic substance. The device includes a reservoir containing a therapeutic substance and an energy converter to cause the release of the substance. ... | 05/29/2007 |
| 7223847 | Method for producing cobalt-protein complex A method for obtaining a cobalt-apoferritin complex according to the present invention includes: the step a) of preparing a solution including a Co2+ ion, a protein, a pH buffer agent and a Co2+ associating agent; and the step b) of adding an o... | 05/29/2007 |
| 7220402 | Alpha-fetoprotein peptides and uses for imaging The invention provides diagnostic procedures wherein the presence or absence of a cell-proliferating disorder, e.g., a breast cancer, may be determined. The imaging agents of the invention include alpha-fetoprotein hydrophilic analogs which have been determined to t... | 05/22/2007 |
| 7199100 | Cyclic peptides, method for preparing and use as angiogenesis inhibitors or activator The invention relates to cyclopeptides, the method of their preparation and their utilization as inhibitors or activators of angiogenesis. These cyclopeptides comprise the following peptide sequence: -Arg-Ile-Lys-Pro-His-Gln-Gly- They can be... | 04/03/2007 |
| 7189405 | Peptide mimics of conserved gonococcal epitopes and methods and compositions using them The present invention relates to peptide mimics of a conserved gonococcal epitope of Neisseria gonorrhoeae, which epitope is not found on human blood group antigens. This invention also relates to methods and compositions using such peptide mimics for the pro... | 03/13/2007 |
| 7183118 | Methods for quantitative proteome analysis of glycoproteins The invention provides a method for identifying and quantifying polyglycopeptides in a sample. The method can include the steps of immobilizing glycopolypeptides to a solid support; cleaving the immobilized glycopolypeptides, thereby releasing non-glycosylated pepti... | 02/27/2007 |
| 7172751 | D-amino acid peptides The present invention provides compounds of the formula X—R1-D-[Dpr, Orn or Lys](A)-R2(Z)-D-[Dpr, Orn or Lys](B)—R3(Y)—NR4R5; or R1(X)-D-[Dpr, Orn or Lys](A)-R2(Z)-D-[Dpr, Orn or Lys]... | 02/06/2007 |
| 7166719 | Fluorinated photosensitizers related to chlorins and bacteriochlorins for photodynamic therapy Provided herein are compounds for detection, diagnosis and treatment of target tissues or target compositions, including hyperproliferative tissues such as tumors, using photodynamic methods. In particular, photosensitizer compounds that collect in hyperproliferativ... | 01/23/2007 |
| 7163918 | Iodothyronine compositions The present invention relates to compositions comprising thyroxine (T4) and triiodothyronine (T3). More specifically, the invention relates to thyroxine (T4) and triiodothyronine (T3) compositions that include a peptide carrier and thyroxine (T4) and triiodothyronin... | 01/16/2007 |
| 7153506 | Use of anti-ferritin monoclonal antibodies in the treatment of some cancers The invention concerns the use, in the preparation of a medicine for treating cancer whereof the cells exhibit overexpression of a product of a gene of the myc-related family, of an anti-ferritin monoclonal antibody or a fragment thereof, said antibody or said fragm... | 12/26/2006 |
| 7138388 | Methods to treat autoimmune and inflammatory conditions This invention provides methods for treating inflammatory or autoimmune diseases by contacting the affected cell or tissue with a therapeutic compound as described herein. Such pathologies include, but are not limited to rheumatoid arthritis, systemic lupus erythmat... | 11/21/2006 |
| 7138105 | Compositions for delivery of therapeutics and other materials, and methods of making and using the same In part, the present invention is directed to compositions comprising a carrier with a metal binding domain, a metal ion, and an active agent. ... | 11/21/2006 |
| 7138104 | Simultaneous imaging of cardiac perfusion and a vitronectin receptor targeted imaging agent The present invention describes a method of concurrent imaging in a mammal comprising: a) administering to said mammal a vitronectin receptor targeted imaging agent and a perfusion imaging agent; and b) concurrentl... | 11/21/2006 |
| 7115268 | Peptides useful for reducing symptoms of toxic shock syndrome and septic shock This invention relates to compositions and methods which provide protection against, or reduce the severity of toxic shock and septic shock from bacterial infections. More particularly it relates to peptides derived from homologous sequences of the family of staphyl... | 10/03/2006 |
