Bizarre Patents
System for magnetically attaching templeless eyewear to a person
A system of eyewear that eliminates the need for hinges on the frames of the eyewear.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 5976493 | Metabolically cleavable dendrimeric polychelants The invention provides polychelant compounds which are useful for example in diagnostic imaging procedures and which are degradable in vivo to release excretable fragments. Such compounds conveniently are of the formula (I): R1 (X1 R... | 11/02/1999 |
| 5976498 | Methods of diagnostic image analysis using metal complexes of nitrogen-containing macrocyclic ligands The present invention is directed to complexes represented by the formula: ##STR1## wherein R, R', R1, R'1, R2, R'2, R3, R'3, R4, R'4, R5, R'5, R... | 11/02/1999 |
| 5968527 | Protection of living systems from the adverse effects of stress Methods and apparatus are described to inhibit the adverse health effects of ischemia, hypoxia, anoxia or other stress by the application of a time-varying field to the region of the affected organ(s) for a short period of time (of the order of 20 minutes... | 10/19/1999 |
| 5965131 | Delivery of diagnostic and therapeutic agents to a target site An improvement in in vivo pretargeting methods for delivering diagnostic or therapeutic agents to a target site in a mammal uses a clearing agent that binds to the target-binding site of the targeting species, whereby non-bound primary targeting species i... | 10/12/1999 |
| 5958408 | Delivery of diagnostic and therapeutic agents to a target site An improvement in in vivo pretargeting methods for delivering diagnostic or therapeutic agents to a target site in a mammal uses a clearing agent that binds to the target-binding site of the targeting species, whereby non-bound primary targeting species i... | 09/28/1999 |
| 5955437 | Use of an anticoagulant as a diagnostic agent Detectably labelled annexines and compositions thereof are disclosed. Also disclosed are methods for diagnosing a disruption or activation of the hemostatic system or a prothrombotic state in an individual suspected of having a hemostatic disorder, by con... | 09/21/1999 |
| 5955586 | Highly boronated derivatives of texaphyrins The present invention is directed to highly boronated derivatives of expanded porphyrins including sapphyrins and texaphyrins, and more particularly to expanded porphyrins substituted with carborane clusters. Such compositions are useful in boron neutron ... | 09/21/1999 |
| 5951473 | Determination of intracellular sodium and potassium ions by NMR New methods for rapid, noninvasive determination of sodium ion in vivo are described. The methods are useful for assessing liver and other organ injury based on a nuclear magnetic resonance determination of intracellular and extracellular sodium in the da... | 09/14/1999 |
| 5945564 | 2,2-dideutero-5-aminolevulinic acid 2,2-Dideutero-5-aminolevulinic acid or its salt, or a hydrate or a solvate thereof, preferably 2,2-dideutero-5-aminolevulinic acid hydrochloride, and a process for preparing 2,2-dideutero-5-aminolevulinic acid are provided. The 2,2-Dideutero-5-aminolevuli... | 08/31/1999 |
| 5932188 | Therapeutic and diagnostic imaging compositions and methods This invention provides therapeutic and diagnostic imaging compositions and methods featuring a polymer comprising units containing a poly(alkylene oxide) moiety linked to the residue of a chelating agent, said polymer having a cytotoxic agent associated ... | 08/03/1999 |
| 5928626 | Contrast agents, consisting of carbohydrate particles The present invention relates to contrast agents comprising water-soluble microbubble-generating carbohydrate microparticles in admixture with at least 10% w/w relative to the overall composition of a non-surface active material which is less water solubl... | 07/27/1999 |
| 5922304 | Gaseous precursor filled microspheres as magnetic resonance imaging contrast agents Novel gas filled microspheres useful as magnetic resonance imaging (MRI) contrast agents are provided.... | 07/13/1999 |
| 5922302 | Detection and therapy of lesions with biotin/avidin-metal chelating protein conjugates Improved methods of detecting and/or treating lesions in a patient are provided. The improved methods comprise the steps of (a) parenterally injecting a subject with a targeting composition comprised of a conjugate of biotin and targeting protein or of an... | 07/13/1999 |
| 5910300 | Amphiphilic linkers for coupling administrable diagnostically or physiologically active agents and bioselective targeting compounds Administrable factors or compositions to be directed to specific sites in the body of human and animal patients which comprise a medically and/or diagnostically effective moiety (I) and, coupled thereto by means of a linker (L), a substance (II) having sp... | 06/08/1999 |
| 5906807 | Method of MRI using biomodulators Biomodulators, optionally linked to imaging-active moieties, can be administered to a host to enhance images thereof, e.g., NMR-, X-ray- or radio-images, preferably by increasing aberrant tissue signal intensity. Biomodulators can also condition tissue to... | 05/25/1999 |
| 5900228 | Bifunctional detection agents having a polymer covalently linked to an MRI agent and an optical dye The invention provides bifunctional detection agents comprising optical dyes covalently linked to at least one magnetic resonance image (MRI) contrast agent. These agents may include a linker, which may be either a coupling moiety or a polymer.... | 05/04/1999 |
| 5888476 | Magnetic resonance blood pool agents The present invention provides compositions comprising contrast agents capable of binding non-covalently to blood proteins. The compositions of the invention provide increased residence time of contrast agents in the vasculature, thus providing effective ... | 03/30/1999 |
| 5886158 | Metal complexes of polyamino oxides, and their utilization in diagnostic imaging The invention concerns gadolinium complexes of formula: ##STR1## in which R represents a group of formula: ##STR2## in which X is Br or I; R1 is H or optionally hydroxylated alkyl; R2 is hydroxylated alkyl; or alternatively R | 03/23/1999 |
| 5876694 | Azavesamicols A method for non-invasively mapping cholinergic innervation in a living brain comprises injecting the brain with a radiolabelled vesamicol (hydroxylated phencyclidine (PCP) isomer trans-2-(4-phenyl-piperidino)cyclohexanol) derivatives with anticholin... | 03/02/1999 |
| 5876698 | Macrocyclic polymer complexing agents, their complexes, process for their production and pharmaceutical agents containing these compounds Polymeric compounds of general formula I (M)n A (I) in which M stands for the radical of a macrocyclic complexing agent, A stands for a backbone molecule, which shows a deficit of n amino groups, n hydroxy g... | 03/02/1999 |
| 5863519 | Composition and method of MRI using both a positive and a negative contrast agent There is provided a contrast medium composition comprising: (a) a first contrast agent comprising a physiologically tolerable manganese compound together with an uptake promoter, having a manganese concentration of at least 0.3 mM or being in a dosage uni... | 01/26/1999 |
| 5849259 | 3-,8-substituted deuteroporphyrin derivatives, pharmaceutical agents containing the latter and process for their production The invention relates to new 3,8-substituted deuteroporphyrin derivatives with various substituents in positions 13 and 17 of the porphyrin skeleton, pharmaceutical agents containing these compounds, their use in diagnosis and therapy as well as process f... | 12/15/1998 |
| 5840701 | Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules Compositions and processes to alleviate free radical toxicity are disclosed based on the use of nitroxides in association with physiologically compatible macromolecules. In particular, hemoglobin-based red cell substitutes are described featuring stable n... | 11/24/1998 |
| 5840276 | Activatable infusable dispersions containing drops of a superheated liquid for methods of therapy and diagnosis Dispersions of superheated drops of immiscible liquids in aqueous continuous phase suitable for infusion into a human or other animal, the drops being vaporizable in a selected body location by ionizing radiation or ultrasound. The dispersions can be used... | 11/24/1998 |
| 5834456 | Polyazamacrocyclofluoromonoalkylphosphonic acids, and their complexes, for use as contrast agents Polyazamacrocyclofluoromonoalkylphosphonic acid compounds are disclosed which form inert complexes with Gd, Mn, Fe or La ions. The complexes are useful as contrast agents for diagnostic purposes.... | 11/10/1998 |
| 5824288 | Thio-substituted pyridines as MRI ligand precursors Novel precursors of ligands or use in MRI contrast agents and which have the formula ##STR1## wherein R2-R.sub.10 are defined herein.... | 10/20/1998 |
| 5817289 | Non-cluster type bismuth compounds The use in diagnostic imaging, in particular X-ray, MRI, ultrasound and scintigraphy, of contrast agents comprising bismuth clusters and/or organic bismuth compounds, and contrast media containing such bismuth compounds. The bismuth compounds are also use... | 10/06/1998 |
| 5817632 | Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules Compositions and processes to alleviate free radical toxicity are disclosed based on the use of nitroxides in association with physiologically compatible macromolecules. In particular, hemoglobin-based red cell substitutes are described featuring stable n... | 10/06/1998 |
| 5817777 | Substituted cyclopentane compounds for use as chelating agents The invention provides as new compounds cis-xis-cis-tetrasubstituted cyclopentane compounds which are expected to be useful as chelating agents for alkaline earths, transition, lanthanide, and actinide metal ions. The compounds have Formula (I). Each of t... | 10/06/1998 |
| 5817017 | Medical devices and materials having enhanced magnetic images visibility Catheters and other medical devices include a non-metallic member having paramagnetic ionic particles fixedly incorporated therethrough in order to provide enhanced detectability when viewed by magnetic imaging regardless of the orientation of the non-met... | 10/06/1998 |
| 5814301 | Use of prostacyclin derivatives to prevent or to treat disorders of the microcirculatory system when x-ray, NMR or ultrasonic contrast media are administered Use of a prostacyclin derivative of general formula I ##STR1## in which R1, X, Y, Z, A, W, D, E, R2 and R3 may have different meanings, for the production of a pharmaceutical agent to prevent or to treat disorders of ... | 09/29/1998 |
| 5807536 | Anatomical imaging with phycocyanins Phycocyanins selectively impregnate biological structures including atherosclerotic plaque and tumors. Imaging of biological structures can be enhanced by tagging to a phycocyanin an atom which is compatible with the or complementary to any of the imaging... | 09/15/1998 |
| 5807831 | Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules Compositions and processes to alleviate free radical toxicity are disclosed based on the use of nitroxides in association with physiologically compatible macromolecules. In particular, hemoglobin-based red cell substitutes are described featuring stable n... | 09/15/1998 |
| 5804561 | Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules Compositions and processes to alleviate free radical toxicity are disclosed based on the use of nitroxides in association with physiologically compatible macromolecules. In particular, hemoglobin-based red cell substitutes are described featuring stable n... | 09/08/1998 |
| 5785953 | Magnetic resonance imaging using hyperpolarized noble gases A method of imaging a spatial distribution of a noble gas by nuclear magnetic resonance spectrometry includes detecting a spatial distribution of at least one noble gas by NMR spectrometry and generating a representation of said spatial distribution of th... | 07/28/1998 |
| 5765562 | Method for determining oxygen concentration using magnetic resonance imaging A method for determining the oxygen concentration of a sample using electron spin resonance enhanced magnetic resonance imaging.... | 06/16/1998 |
| 5762909 | Tumor targeting with polymeric molecules having extended conformation Enhanced drug delivery to tumor tissue is obtained by attaching drug molecules to elongated polypeptide carrier molecules several orders of magnitude longer than wide. These are chosen to have a high net negative charge. The carrier molecules are created ... | 06/09/1998 |
| 5759519 | Method for the intracellular delivery of biomolecules using thiocationic lipids Lipid molecules bearing a cationic charge are described. These cationic lipids are useful in the delivery of biomolecules, such as oligonucleotides, nucleic acids, peptides, diagnostic imaging agents, proteins and drug molecules. In the form of liposomes,... | 06/02/1998 |
| 5753204 | Biosynthetic binding proteins for immunotargeting Disclosed is a formulation for targeting an epitope on an antigen expressed in a mammal. The formulation comprises a pharmaceutically acceptable carrier together with a dimeric biosynthetic construct for binding at least one preselected antigen. The biosy... | 05/19/1998 |
| 5741893 | Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules Compositions and processes to alleviate free radical toxicity are disclosed based on the use of nitroxides in association with physiologically compatible macromolecules. In particular, hemoglobin-based red cell substitutes are described featuring stable n... | 04/21/1998 |
