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A haircutting appliance comprises an enclosed housing having a hollow handle connecting the housing to a vacuum source to carry away cut hairs from a subject's head.
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| Number | Title | Issue Date |
| 8187573 | In vivo detection of apoptosis The invention provides methods and products, such as kits, useful for determining the apoptotic state of cells in an organism, comprising detecting the presence or abundance of at least one caspase affinity labeling agent in the cells of an animal into which at leas... | 05/29/2012 |
| 8187572 | Diabetogenic rat model The present invention provides a method of producing diabetic rats, and a method for identifying compounds that reverse diabetes in said rats. ... | 05/29/2012 |
| 8183208 | Targeted delivery of drugs for the treatment of viral infections Conjugates of transferrin or transcobalamin with anti-viral agents are useful in the treatment of viral infections. Suitable anti-viral agents include apoptosis inducing compounds, compounds which inhibit the replication of the virus, a cytotoxic antibiotic, an alky... | 05/22/2012 |
| 8173104 | Controlled-release immunogenic formulations to modulate immune response Single-dose controlled-release immunogenic formulations, such as vaccines, based on bioerodible polyanhydride copolymer or homopolymer microparticles for the control of immune response mechanisms are provided. The copolymer or homopolymer microparticles degrade by s... | 05/08/2012 |
| 8173103 | Inhibition of cancer metastasis P-Selectin on platelets and endothelium binds cell surface chondroitin sulfate (CS) proteoglycans, which are abundantly and stably expressed on the surface many cancer cells. Binding of the cancer cells through the CS moieties may be blocked to inhibit the interacti... | 05/08/2012 |
| 8153102 | Process for manufacturing pharmaceutical composition comprises of in the treatment of asthma (obstructive lung disease) The invention relates to process for the preparation of formulations comprising a microorganism Mycobacterium w for the management of bronchial Asthma (obstructive lung disease). ... | 04/10/2012 |
| 8147801 | Methods of using alpha-methylglucoside (AMG) as an indicator for glucose absorption and excretion Presented here are methods using alpha-methylglucoside (AMG) in vivo as an indicator for glucose absorption from the gastrointestinal (GI) system or glucose excretion in the urine after oral administration of AMG. The methods find use in, for example, but not limite... | 04/03/2012 |
| 8142760 | Vaccination for The present invention include a method of protecting an animal against Lawsonia intracellularis infections, the method including administering a dose of live virulent L. intracellularis to the animal, allowing a subclinical L. intracellularis in... | 03/27/2012 |
| 8142761 | Method of predicting spot formation on the skin using spot site-accelerating genes as an indicator thereof and method of screening inhibitors of spot formation on the skin The present invention provides a skin test method for predicting the formation of spots in the skin. This method is characterized by judging skin to be susceptible to spot formation in the case expression of genes consisting of MLSTD1, MOGAT1, FADS2, FADS1, HSD3B1, ... | 03/27/2012 |
| 8142762 | Methods of using GPR101 receptors to identify modulators of hypothalamic proopiomelanocortin (POMC)-derived biologically active peptide secretion The present invention relates to methods of using GPR101 G protein-coupled receptor (GPCR) to screen candidate compounds as modulators of hypothalamic proopiomelanocortin (POMC)-derived biologically active peptide secretion. Modulators of GPR101 receptor modulate hy... | 03/27/2012 |
| 8124056 | High throughput genetic screening of lipid and cholesterol processing using fluorescent compounds The present invention utilizes fluorescent lipids, particularly quenched phospholipid or cholesterol analogues, to facilitate screening for phenotypes representing perturbations of lipid and/or cholesterol processing in a vertebrate; screening for genetic mutations ... | 02/28/2012 |
| 8110177 | Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions Disclosed is a method of treating small intestinal bacterial overgrowth (SIBO) or a SIBO-caused condition in a human subject. SIBO-caused conditions include irritable bowel syndrome, fibromyalgia, chronic pelvic pain syndrome, chronic fatigue syndrome, depression, i... | 02/07/2012 |
| 8101159 | In vivo methods of identifying compounds which target suppressed cancer cells In vitro and in vivo methods for identifying compounds capable of targeting suppressed cancer cells such as micrometastatic cells. The in vitro method includes the steps of comparing the response to a test compound of cancer cells grown on a suppressing cell support... | 01/24/2012 |
| 8097239 | Controlled-release formulations The present invention relates to formulations of a lipid based controlled-release matrix, a polyhydroxy component and a bioactive agent. Such formulation are useful in the delivery of the bioactive compounds. The invention also relates to the use of a polyhydroxy co... | 01/17/2012 |
| 8092781 | Treatment of sinusitis in mammals with clostridia neurotoxins A method is disclosed for blocking or reducing physiological reaction in a mammal to the interaction of IgE antibodies present in said mammal upon contact with the corresponding antigen, by the administration to said mammal of a therapeutically effective amount of a... | 01/10/2012 |
| 8088361 | Treatment of allergic rhinitis in mammals with neurotoxins A method is disclosed for blocking or reducing physiological reaction in a mammal to the interaction of IgE antibodies present in said mammal upon contact with the corresponding antigen, by the administration to said mammal of a therapeutically effective amount of a... | 01/03/2012 |
| 8088360 | Treatment of infectious rhinitis in mammals with clostridia neurotoxins A method is disclosed for blocking or reducing physiological reaction in a mammal to the interaction of IgE antibodies present in said mammal upon contact with the corresponding antigen, by the administration to said mammal of a therapeutically effective amount of a... | 01/03/2012 |
| 8066972 | Altering memory by affecting staufen function The present invention provides methods for screening a pharmaceutical agent for its ability to modulate long term memory formation, performance of a hippocampal-dependent cognitive task or STAUFEN function. The present invention also provides methods for modulating ... | 11/29/2011 |
| 8062625 | Cancer immunotherapy predictive parameters The invention relates to a method for predicting the efficacy of a cancer immunotherapy of an individual with respect to clinical benefit, which comprises the following steps: —providing a blood sample of said individual, —(a1) determining the number of lymphocy... | 11/22/2011 |
| 8052960 | Netrin-1 as a biomarker of injury and disease Detection and diagnosis of injury and/or disease in a subject can be key to preventing irreversible damage and death. Methods of aiding detection and assessment of a disease or condition in a subject are which include assaying netrin-1 protein and/or nucleic acid in... | 11/08/2011 |
| 8021645 | Synthesis of human secretory IgA and IgM and the formation of a medicament therefrom A composition for treating a subject is provided. The composition includes antigen specific dimeric secretory IgA and pentameric IgM therapeutic. A process for manufacturing a medicament for the treatment of C. difficile associated disease in a human is also ... | 09/20/2011 |
| 8007770 | Purified linear polypeptide epitopes from walnuts and associated methods A purified Ig-E binding immunogenic polypeptide the amino acid sequence of which consists of SEQ ID NO:1 is disclosed. The purified amino acid sequence is a major allergen of the walnut Juglans regia. Also described are a diagnostic test kit and use of the pu... | 08/30/2011 |
| 7998461 | cancer therapeutics and related therapeutic methods Therapeutic methods for treatment of solid tumor cancer cell masses, as can be effected using therapeutic compositions comprising Salmonella species/strains and related compositions. ... | 08/16/2011 |
| 7998460 | Prevention of deficits in neurogenesis with anti-inflammatory agents Methods are provided for protecting an individual from adverse long-term effects of neuroinflammation. Inflammatory blockade maintains neurogenesis capability after cranial irradiation by reducing the negative effects of activated microglia on neural precursor cells... | 08/16/2011 |
| 7959901 | EGFR inhibitors promote axon regeneration Compositions and methods for promoting neural regeneration in a patient determined to have a lesion in a mature CNS neuron are disclosed. The method comprises the step of contacting the neuron with an EGFR inhibitor sufficient to promote regeneration of the neuron. | 06/14/2011 |
| 7951778 | Use of compounds having the biological activity of vasoactive intestinal peptide for the treatment of sarcoidosis The present invention relates to peptides which are highly biologically and pharmacologically active as therapeutic drug for the treatment of diseases related to sarcoidosis. The peptides which can be used according to the invention for the treatment of said disease... | 05/31/2011 |
| 7947255 | Fluorescent substrates for neurotransmitter transporters The invention is based on the finding that IDT307 and analogs thereof are fluorescent substrates transported by several neurotransmitter transporters. Provided are methods for the analysis of neurotransmitter transport and binding using IDT307 and its analogs. The i... | 05/24/2011 |
| 7939052 | Method of measuring the biological activity of an urotensin II receptor Administration of U-II to rats caused an increase in the redness or the skin temperature of the ear of the rats. The increase was inhibited by compounds that decease the biological activity of the U-II/UT receptor. Thus, the present invention provides methods of mea... | 05/10/2011 |
| 7927580 | Tat-based immunomodulatory compositions and methods of their discovery and use A method for identifying new immunomodulatory chemical entities (NICE) comprising reacting a candidate NICE with a Tat SH3 binding domain, identifying the bound candidate NICE and determining whether the candidate NICE induces monocytes to differentiate into dendrit... | 04/19/2011 |
| 7923000 | Methods of determining efficacy of treatments of inflammatory diseases of the bowel Novel methods of determining efficacy of a treatment of inflammatory diseases of the bowel in mammals are provided. The methods are of use in screening and determining the efficacy of treatments of inflammatory diseases of the bowel, and for determining the efficacy... | 04/12/2011 |
| 7923001 | Compositions and methods for diagnosing and treating urinary tract infections The present invention relates to methods and compositions for treating urinary tract infections. In particular, the present invention relates to vaccines and immune modulators for treating urinary tract infections. ... | 04/12/2011 |
| 7914769 | Compounds for treating human papillomavirus Methods and compositions for treating human papillomavirus infections are described. ... | 03/29/2011 |
| 7875259 | Biological materials and methods useful in the diagnosis and treatment of diseases The present invention relates to a method of making a β-form of a prion protein which preferably has more β-sheet than α-helix structure and is soluble in the absence of a denaturant and/or is non-aggregated and exhibits partial resistance to digestion with prote... | 01/25/2011 |
| 7858073 | Oral killed vaccines and method for providing same There is described a method for selecting microbial isolates for use in oral killed vaccines against abnormal microbial colonization of mucosal surfaces by the microbes. The method comprises evaluating capacity of a plurality of different isolates of a microbe to ac... | 12/28/2010 |
| 7846420 | subspecies vaccines and methods of using the same The invention relates to vaccine compositions composed of at least one Mycobacterium avium subspecies paratuberculosis (MAP) antigen, or attenuated or killed MAP for use in methods of immunizing a human against a MAP infection, preventing or treating a... | 12/07/2010 |
| 7815896 | Type III secretion pathway in and uses therefor Disclosed is a newly identified and characterized type III secretion system in Aeromonas salmonicida. The invention also encompasses the use of components of the novel secretion system in immunoprotection against A. salmonicida infection, as well as ot... | 10/19/2010 |
| 7815895 | Method for activating efferent sympathetic nerves innervating adipose tissues to improve obesity and symptoms associated therewith A method for activating an efferent sympathetic nerve innervating an adipose tissue and improving obesity-associated symptoms is provided, comprising stimulating an afferent vagal nerve from the liver without directly enhancing peroxisome proliferator-activated rece... | 10/19/2010 |
| 7807139 | Use of outer membrane protein A (OMPA) in treatment/prevention/diagnosis of infections caused by and other gram-negative bacteria The present invention provides a method for the treatment and/or prevention of bacterial infection caused by Klebsiella pneumoniae and other gram-negative bacteria in central nervous system and/or peripheral blood circulation in a mammal by administering effe... | 10/05/2010 |
| 7807138 | Biomarkers of metabolic responses to hepatic drugs Methods for the measurement and prediction of response to hepatotoxicants and carcinogens through the detection of metabolites in a mammal are provided. The metabolites can be used as biomarkers, including efficacy biomarkers, surrogate biomarkers, and toxicity biom... | 10/05/2010 |
| 7785569 | Lyophilized edible food incorporating a marker A standardized, lyophilized edible food containing a biologically safe stable marker for use in the measurement of gastric emptying by the quantification of marker excreted in the breath of the patient. ... | 08/31/2010 |
