A forehead support apparatus for resting a standing users forehead against a wall above a bathroom commode or urinal or beneath a showerhead.
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| Number | Title | Issue Date |
| 8110181 | Method of treating with interferons A method of treating tuberculosis comprising administering an aerosolized interferon such as interferon α, interferon β or interferon γ in a therapeutically effective amount is provided herein. Also, pharmaceutical compositions of one or more aerosolized i... | 02/07/2012 |
| 8105572 | Method of treating tuberculosis with interferons A method of treating tuberculosis comprising administering an aerosolized interferon such as interferon α, interferon β or interferon γ in a therapeutically effective amount is provided herein. Further, a method of reducing the infectivity of tuberculosis or redu... | 01/31/2012 |
| 8105571 | Method of treating pulmonary disease with interferons A method of treating a pulmonary disease such as, for instance idiophathic pulmonary fibrosis (IPF), mixed connective tissue disease and asthma, comprising administering an aerosolized interferon such as interferon γ in a therapeutically effective amount is provide... | 01/31/2012 |
| 8088368 | Antiviral compounds The invention is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds. ... | 01/03/2012 |
| 8084022 | Stabilizing alkylglycoside compositions and methods thereof The present invention relates to alkylglycoside-containing compositions and methods for increasing the stability, reducing the aggregation and immunogenicity, increasing the biological activity, and reducing or preventing fibrillar formation of a peptide, polypeptid... | 12/27/2011 |
| 8075877 | Broad spectrum immune and antiviral gene modulation by oral interferon An antiviral/immunomodulatory response in an animal is induced by oral administration to an infected animal, including humans, of a human α-interferon. Methods of conferring resistance or mitigating the effects of exposure to a virus including avian influenza are d... | 12/13/2011 |
| 8075878 | Broad spectrum immune and antiviral gene modulation by oral interferon An antiviral/immunomodulatory response in an animal is induced by oral administration to an infected animal, including humans, of a human α-interferon. Methods of conferring resistance or mitigating the effects of exposure to a virus including avian influenza are d... | 12/13/2011 |
| 7833521 | Methods of treating using hormone-albumin fusion proteins Biologically active polypeptides comprising a therapeutically active polypeptide fused to human serum albumin or a variant of human serum albumin, methods for preparation, nucleotide sequences encoding such fusion polypeptides, expression cassettes comprising such n... | 11/16/2010 |
| 7807143 | Alpha-MSH therapies for treatment of autoimmune disease Methods and compositions for the enteral treatment of autoimmune disease such a multiple sclerosis with polypeptide therapeutics. Enteral therapeutics comprise monomeric alpha-MSH polypeptides such as ACTH. Therapeutic formulations of the invention may be used to re... | 10/05/2010 |
| 7731947 | Composition and dosage form comprising an interferon particle formulation and suspending vehicle A liquid composition in an osmotic drug delivery system and a dosage form in an osmotic drug delivery system is disclosed comprising an amphiphilic molecule, a non-aqueous liquid solvent, and a pharmaceutically active agent. ... | 06/08/2010 |
| 7727519 | Method for treating hepatitis C virus with omega interferon Methods for the treatment of interferon-response disorders by administration of an interferon alone or in combination with adjunctive therapy are described. The invention encompasses providing to a patient both a formulation of an interferon that is suitable for sho... | 06/01/2010 |
| 7691367 | Branched polyalkylene glycols The present invention provides branched polyalkylene glycols useful as a chemically modifying agent for physiologically active polypeptides, wherein two single-chain polyalkylene glycols are linked to a group having a cyclic structure other than a plane structure, a... | 04/06/2010 |
| 7635466 | DNA sequences, recombinant DNA molecules and processes for producing human fibroblast interferon-like polypeptides DNA sequences, recombinant DNA molecules and hosts transformed with them which produce polypeptides displaying a biological or immunological activity of human fibroblast interferon, the genes coding for these polypeptides and methods of making and using these DNA se... | 12/22/2009 |
| 7632491 | Stable pegylated interferon formulation The present invention relates to lyophilized formulations of pegylated interferon which are prepared using trehalose as a cryoprotectant. The formulations have a low moisture content, which helps stabilize the pegylated interferon during storage of the formulations ... | 12/15/2009 |
| 7628980 | Modified vaccinia virus ankara for the vaccination of neonates The invention relates inter alia to a method for inducing a long-term protection in an animal against foreign antigens and tumor antigens comprising the step of administering to the animal at least one factor selected from type I interferons and Flt-3, and to a meth... | 12/08/2009 |
| 7625554 | Treatment of alzheimer's disease The present invention provides a method for treating cognitive decline in a patient by administering to the patient at least about 100 units per day of α-interferon. ... | 12/01/2009 |
| 7597884 | Hyperglycosylated polypeptide variants and methods of use The present invention provides synthetic Type I interferon receptor polypeptide agonists comprising consensus or hybrid Type I interferon receptor polypeptide agonists, containing one or more native or non-native glycosylation sites. The present invention provides s... | 10/06/2009 |
| 7588755 | DNA sequences, recombinant DNA molecules and processes for producing human fibroblast interferon-like polypeptides DNA sequences, recombinant DNA molecules and hosts transformed with them which produce polypeptides displaying a biological or immunological activity of human fibroblast interferon, the genes coding for these polypeptides and methods of making and using these DNA se... | 09/15/2009 |
| RE40882 | Antiviral nasal drops comprising recombinant interferon a biocompatible polymer and an antioxidant The present invention can be used in pharmacology specifically in the preparation of interferon-containing compositions, which are capable of conserving their biological activity and can be administered intranasally, e.g. in the preparation of nasal drops. This inve... | 08/25/2009 |
| 7575742 | Method of treating autoimmune diseases with interferon-beta and IL-2R antagonist Disclosed is a method of administering an interleukin-2 receptor (IL-2R) antagonist to a subject to treat an autoimmune disease. In particular embodiments, the IL-2R antagonist is an anti-IL-2R monoclonal antibody specific for one or more chains of the IL-2R, such a... | 08/18/2009 |
| 7572437 | Long acting human interferon analogs Compositions, kits and methods are provided for Interferon analogs in order to promote general health or for therapeutic treatment of diseases. Human interferon analogs are made by fusion of interferon with human serum albumin. The bio-assay shows that the interfero... | 08/11/2009 |
| 7449176 | Treatment of inflammatory bowel disease with IFN-γ inhibitors The invention concerns a method for the prevention or treatment of inflammatory bowel disease by administering an interferon-γ inhibitor. The invention further concerns pharmaceutical compositions and bispecific molecules useful in such method. ... | 11/11/2008 |
| 7435410 | Methods of treatment with interferson and albumin fusion protein Biologically active polypeptides comprising a therapeutically active polypeptide fused to human serum albumin or a variant thereof, methods for the preparation thereof, nucleotide sequences encoding such fusion polypeptides, expression cassettes comprising such nucl... | 10/14/2008 |
| 7431921 | Interferon beta-like molecules The invention relates to a conjugate exhibiting interferon β (IFNB) activity and comprising at least one first non-polypeptide moiety covalently attached to an IFNB polypeptide, the amino acid sequence of which differs from that of wildtype human IFNB in at least o... | 10/07/2008 |
| 7431920 | Method of treating IL-10 deficiency A method for treating an IL-10 deficiency in a human subject is described, where a person having an IL-10 deficiency is identified and treated with interferon-tau (IFNτ) at a dose sufficient to increase the IL-10 level. ... | 10/07/2008 |
| 7416723 | Therapeutic compositions and methods useful in modulating protein tyrosine phosphatases In one embodiment, a therapeutic composition containing a pentavalent antimonial is provided. The pentavalent antimonial can be sodium stibogluconate, levamisole, ketoconazole, and pentamidine and biological equivalents of said compounds. Additionally, pentavalent a... | 08/26/2008 |
| 7393839 | Polymorphic antiviral nucleoside compounds The present invention relates to the polymorphic crystalline hydrochloride salts of a nucleoside valinate ester according to formula Ib, methods of treating diseases mediated by Hepatitis C Virus and pharmaceutical composition containing Ib | 07/01/2008 |
| 7378387 | Method of suppressing immune response by reducing intracellular content of glutathione in macrophages and monocytes A method of suppressing immune responses, comprising administering to a patient in need thereof an effective amount of a composition comprising a substance capable of reducing the content of reductive glutathione in macrophages. ... | 05/27/2008 |
| 7371372 | Compositions comprising IMPDH inhibitors and uses thereof for treating HCV infection The present invention relates to optimal compositions useful in treating HCV infections in humans. These compositions comprise alpha-interferon or pegylated alpha-interferon and an IMPDH inhibitor selected from VX-148 or VX-944, wherein the IMPDH inhibitor is presen... | 05/13/2008 |
| 7365165 | IL-1 antagonist formulations Formulations of an interleukin-1 (IL-1) antagonist are provided including a pre-lyophilized formulation, a reconstituted lyophilized formulation, and a stable liquid formulation. Preferably, the IL-1 antagonist is an IL-1 trap composed of a dimer of two fusion prote... | 04/29/2008 |
| 7354899 | Methods of treating autoimmune diseases comprising administering CXCR4 antagonists The invention provides a variety of therapeutic uses for CXCR4 antagonists. In various embodiments, CXCR4 antagonists may be used as therapeutically as follows, or to manufacture a medicament for such therapeutic treatments: reducing interferon gamma production by T... | 04/08/2008 |
| 7344709 | Treatment of hepatitis C in the Asian population with subcutaneous interferon-beta The present invention relates to the use of recombinant IFN-beta for the production of a medicament for the treatment of HCV infection by subcutaneous administration to patients of Asian race, which failed to respond to a previous treatment with interferon-alpha, is... | 03/18/2008 |
| 7342018 | Urokinase inhibitors and uses thereof The invention relates to the use of derivatives of 3-amidinophenylalanine as urokinase inhibitors for treating malignant tumors and the formation of metastases. ... | 03/11/2008 |
| 7338976 | Heterocyclic esters or amides for vision and memory disorders This invention relates to pharmaceutical compositions and methods for treating a vision disorder, improving vision, treating memory impairment, or enhancing memory performance using heterocyclic esters and amides. ... | 03/04/2008 |
| 7323300 | Methods for cancer prognosis and diagnosis The invention provides methods for prognosis, diagnosis, staging and disease progression in human cancer patients related to expression levels of a plurality of genes that are differentially expressed in chemotherapeutic drug resistant and drug sensitive tumor cells... | 01/29/2008 |
| 7309719 | Stabilized pharmaceutical preparation of gamma-aminobutyric acid derivatives and process for preparing the same The present invention provides a stabilized pharmaceutical preparation of a 4-amino-3-substituted-butanoic acid derivative which can be obtained by incorporating an amino acid as a stabilizer. ... | 12/18/2007 |
| 7300656 | Treatment of inflammatory bowel disease with IFN-gamma inhibitors The invention concerns a method for the prevention or treatment of inflammatory bowel disease by administering an interferon-γ inhibitor. The invention further concerns pharmaceutical compositions and bispecific molecules useful in such method. ... | 11/27/2007 |
| 7294332 | Combination therapy (temozolomide and α-IFN) for advanced cancer There is disclosed a method for treating advanced cancer in patients in need of such treating. Temozolomide and alpha interferon are administered in combination in amounts sufficient to achieve a clinical response. ... | 11/13/2007 |
| 7291713 | Branched polyalkylene glycols The present invention provides a branched polyalkylene glycol wherein three or more single-chain polyalkylene glycols and a group having reactivity with an amino acid side chain, the N-terminal amino group or the C-terminal carboxyl group in a polypeptide or a group... | 11/06/2007 |
| 7279597 | Phenyl amine carboxylic acid compounds and compositions for delivering active agents Phenyl amine carboxylic acid compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. ... | 10/09/2007 |