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Patent No. 6681419

Forehead support apparatus 

A forehead support apparatus for resting a standing users forehead against a wall above a bathroom commode or urinal or beneath a showerhead.

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Class 424/85.4 - Interferon


Subclass of Class 424 - Drug, bio-affecting and body treating compositions
Definition: Subject matter in which the lymphokine is a protein elaborated
No. of patents: 499
Last issue date: 02/07/2012


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NumberTitleIssue Date
8110181Method of treating with interferons
A method of treating tuberculosis comprising administering an aerosolized interferon such as interferon α, interferon β or interferon γ in a therapeutically effective amount is provided herein. Also, pharmaceutical compositions of one or more aerosolized i...
02/07/2012
8105572Method of treating tuberculosis with interferons
A method of treating tuberculosis comprising administering an aerosolized interferon such as interferon α, interferon β or interferon γ in a therapeutically effective amount is provided herein. Further, a method of reducing the infectivity of tuberculosis or redu...
01/31/2012
8105571Method of treating pulmonary disease with interferons
A method of treating a pulmonary disease such as, for instance idiophathic pulmonary fibrosis (IPF), mixed connective tissue disease and asthma, comprising administering an aerosolized interferon such as interferon γ in a therapeutically effective amount is provide...
01/31/2012
8088368Antiviral compounds
The invention is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds. ...
01/03/2012
8084022Stabilizing alkylglycoside compositions and methods thereof
The present invention relates to alkylglycoside-containing compositions and methods for increasing the stability, reducing the aggregation and immunogenicity, increasing the biological activity, and reducing or preventing fibrillar formation of a peptide, polypeptid...
12/27/2011
8075877Broad spectrum immune and antiviral gene modulation by oral interferon
An antiviral/immunomodulatory response in an animal is induced by oral administration to an infected animal, including humans, of a human α-interferon. Methods of conferring resistance or mitigating the effects of exposure to a virus including avian influenza are d...
12/13/2011
8075878Broad spectrum immune and antiviral gene modulation by oral interferon
An antiviral/immunomodulatory response in an animal is induced by oral administration to an infected animal, including humans, of a human α-interferon. Methods of conferring resistance or mitigating the effects of exposure to a virus including avian influenza are d...
12/13/2011
7833521Methods of treating using hormone-albumin fusion proteins
Biologically active polypeptides comprising a therapeutically active polypeptide fused to human serum albumin or a variant of human serum albumin, methods for preparation, nucleotide sequences encoding such fusion polypeptides, expression cassettes comprising such n...
11/16/2010
7807143Alpha-MSH therapies for treatment of autoimmune disease
Methods and compositions for the enteral treatment of autoimmune disease such a multiple sclerosis with polypeptide therapeutics. Enteral therapeutics comprise monomeric alpha-MSH polypeptides such as ACTH. Therapeutic formulations of the invention may be used to re...
10/05/2010
7731947Composition and dosage form comprising an interferon particle formulation and suspending vehicle
A liquid composition in an osmotic drug delivery system and a dosage form in an osmotic drug delivery system is disclosed comprising an amphiphilic molecule, a non-aqueous liquid solvent, and a pharmaceutically active agent. ...
06/08/2010
7727519Method for treating hepatitis C virus with omega interferon
Methods for the treatment of interferon-response disorders by administration of an interferon alone or in combination with adjunctive therapy are described. The invention encompasses providing to a patient both a formulation of an interferon that is suitable for sho...
06/01/2010
7691367Branched polyalkylene glycols
The present invention provides branched polyalkylene glycols useful as a chemically modifying agent for physiologically active polypeptides, wherein two single-chain polyalkylene glycols are linked to a group having a cyclic structure other than a plane structure, a...
04/06/2010
7635466DNA sequences, recombinant DNA molecules and processes for producing human fibroblast interferon-like polypeptides
DNA sequences, recombinant DNA molecules and hosts transformed with them which produce polypeptides displaying a biological or immunological activity of human fibroblast interferon, the genes coding for these polypeptides and methods of making and using these DNA se...
12/22/2009
7632491Stable pegylated interferon formulation
The present invention relates to lyophilized formulations of pegylated interferon which are prepared using trehalose as a cryoprotectant. The formulations have a low moisture content, which helps stabilize the pegylated interferon during storage of the formulations ...
12/15/2009
7628980Modified vaccinia virus ankara for the vaccination of neonates
The invention relates inter alia to a method for inducing a long-term protection in an animal against foreign antigens and tumor antigens comprising the step of administering to the animal at least one factor selected from type I interferons and Flt-3, and to a meth...
12/08/2009
7625554Treatment of alzheimer's disease
The present invention provides a method for treating cognitive decline in a patient by administering to the patient at least about 100 units per day of α-interferon. ...
12/01/2009
7597884Hyperglycosylated polypeptide variants and methods of use
The present invention provides synthetic Type I interferon receptor polypeptide agonists comprising consensus or hybrid Type I interferon receptor polypeptide agonists, containing one or more native or non-native glycosylation sites. The present invention provides s...
10/06/2009
7588755DNA sequences, recombinant DNA molecules and processes for producing human fibroblast interferon-like polypeptides
DNA sequences, recombinant DNA molecules and hosts transformed with them which produce polypeptides displaying a biological or immunological activity of human fibroblast interferon, the genes coding for these polypeptides and methods of making and using these DNA se...
09/15/2009
RE40882Antiviral nasal drops comprising recombinant interferon a biocompatible polymer and an antioxidant
The present invention can be used in pharmacology specifically in the preparation of interferon-containing compositions, which are capable of conserving their biological activity and can be administered intranasally, e.g. in the preparation of nasal drops. This inve...
08/25/2009
7575742Method of treating autoimmune diseases with interferon-beta and IL-2R antagonist
Disclosed is a method of administering an interleukin-2 receptor (IL-2R) antagonist to a subject to treat an autoimmune disease. In particular embodiments, the IL-2R antagonist is an anti-IL-2R monoclonal antibody specific for one or more chains of the IL-2R, such a...
08/18/2009
7572437Long acting human interferon analogs
Compositions, kits and methods are provided for Interferon analogs in order to promote general health or for therapeutic treatment of diseases. Human interferon analogs are made by fusion of interferon with human serum albumin. The bio-assay shows that the interfero...
08/11/2009
7449176Treatment of inflammatory bowel disease with IFN-γ inhibitors
The invention concerns a method for the prevention or treatment of inflammatory bowel disease by administering an interferon-γ inhibitor. The invention further concerns pharmaceutical compositions and bispecific molecules useful in such method. ...
11/11/2008
7435410Methods of treatment with interferson and albumin fusion protein
Biologically active polypeptides comprising a therapeutically active polypeptide fused to human serum albumin or a variant thereof, methods for the preparation thereof, nucleotide sequences encoding such fusion polypeptides, expression cassettes comprising such nucl...
10/14/2008
7431921Interferon beta-like molecules
The invention relates to a conjugate exhibiting interferon β (IFNB) activity and comprising at least one first non-polypeptide moiety covalently attached to an IFNB polypeptide, the amino acid sequence of which differs from that of wildtype human IFNB in at least o...
10/07/2008
7431920Method of treating IL-10 deficiency
A method for treating an IL-10 deficiency in a human subject is described, where a person having an IL-10 deficiency is identified and treated with interferon-tau (IFNτ) at a dose sufficient to increase the IL-10 level. ...
10/07/2008
7416723Therapeutic compositions and methods useful in modulating protein tyrosine phosphatases
In one embodiment, a therapeutic composition containing a pentavalent antimonial is provided. The pentavalent antimonial can be sodium stibogluconate, levamisole, ketoconazole, and pentamidine and biological equivalents of said compounds. Additionally, pentavalent a...
08/26/2008
7393839Polymorphic antiviral nucleoside compounds
The present invention relates to the polymorphic crystalline hydrochloride salts of a nucleoside valinate ester according to formula Ib, methods of treating diseases mediated by Hepatitis C Virus and pharmaceutical composition containing Ib
07/01/2008
7378387Method of suppressing immune response by reducing intracellular content of glutathione in macrophages and monocytes
A method of suppressing immune responses, comprising administering to a patient in need thereof an effective amount of a composition comprising a substance capable of reducing the content of reductive glutathione in macrophages. ...
05/27/2008
7371372Compositions comprising IMPDH inhibitors and uses thereof for treating HCV infection
The present invention relates to optimal compositions useful in treating HCV infections in humans. These compositions comprise alpha-interferon or pegylated alpha-interferon and an IMPDH inhibitor selected from VX-148 or VX-944, wherein the IMPDH inhibitor is presen...
05/13/2008
7365165IL-1 antagonist formulations
Formulations of an interleukin-1 (IL-1) antagonist are provided including a pre-lyophilized formulation, a reconstituted lyophilized formulation, and a stable liquid formulation. Preferably, the IL-1 antagonist is an IL-1 trap composed of a dimer of two fusion prote...
04/29/2008
7354899Methods of treating autoimmune diseases comprising administering CXCR4 antagonists
The invention provides a variety of therapeutic uses for CXCR4 antagonists. In various embodiments, CXCR4 antagonists may be used as therapeutically as follows, or to manufacture a medicament for such therapeutic treatments: reducing interferon gamma production by T...
04/08/2008
7344709Treatment of hepatitis C in the Asian population with subcutaneous interferon-beta
The present invention relates to the use of recombinant IFN-beta for the production of a medicament for the treatment of HCV infection by subcutaneous administration to patients of Asian race, which failed to respond to a previous treatment with interferon-alpha, is...
03/18/2008
7342018Urokinase inhibitors and uses thereof
The invention relates to the use of derivatives of 3-amidinophenylalanine as urokinase inhibitors for treating malignant tumors and the formation of metastases. ...
03/11/2008
7338976Heterocyclic esters or amides for vision and memory disorders
This invention relates to pharmaceutical compositions and methods for treating a vision disorder, improving vision, treating memory impairment, or enhancing memory performance using heterocyclic esters and amides. ...
03/04/2008
7323300Methods for cancer prognosis and diagnosis
The invention provides methods for prognosis, diagnosis, staging and disease progression in human cancer patients related to expression levels of a plurality of genes that are differentially expressed in chemotherapeutic drug resistant and drug sensitive tumor cells...
01/29/2008
7309719Stabilized pharmaceutical preparation of gamma-aminobutyric acid derivatives and process for preparing the same
The present invention provides a stabilized pharmaceutical preparation of a 4-amino-3-substituted-butanoic acid derivative which can be obtained by incorporating an amino acid as a stabilizer. ...
12/18/2007
7300656Treatment of inflammatory bowel disease with IFN-gamma inhibitors
The invention concerns a method for the prevention or treatment of inflammatory bowel disease by administering an interferon-γ inhibitor. The invention further concerns pharmaceutical compositions and bispecific molecules useful in such method. ...
11/27/2007
7294332Combination therapy (temozolomide and α-IFN) for advanced cancer
There is disclosed a method for treating advanced cancer in patients in need of such treating. Temozolomide and alpha interferon are administered in combination in amounts sufficient to achieve a clinical response. ...
11/13/2007
7291713Branched polyalkylene glycols
The present invention provides a branched polyalkylene glycol wherein three or more single-chain polyalkylene glycols and a group having reactivity with an amino acid side chain, the N-terminal amino group or the C-terminal carboxyl group in a polypeptide or a group...
11/06/2007
7279597Phenyl amine carboxylic acid compounds and compositions for delivering active agents
Phenyl amine carboxylic acid compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. ...
10/09/2007
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