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| Number | Title | Issue Date |
| 7371393 | Methods for reducing fecal shedding The present invention provides methods for reducing shedding in an animal. Generally, the method includes administcriirn to an animal a composition including siderophore receptor polypeptides and porins from gram negative microbes, and preferably, lipopolysaccarhide... | 05/13/2008 |
| 7341732 | Methods for treating mastitis in a milk producing animal The present invention provides methods for treating mastitis in a milk producing animal. The methods include administering compositions including siderophore receptor polypeptides and porins from gram negative microbes, and preferably, lipopolysaccarhide at a concen... | 03/11/2008 |
| 7201912 | Recombinant immunogenic compositions and methods for protecting against lethal infections from Recombinant immunogenic compositions and methods for protecting against lethal infections from Bacillus anthracis having a variant of recombinant Bacillus anthracis protective antigen (rPA) and a variant of recombinant Bacillus anthracis lethal ... | 04/10/2007 |
| 7147857 | Methods for treating high somatic cell counts The present invention provides methods for treating an animal having a high somatic cell count. The methods include administering compositions including siderophore receptor polypeptides and porins from gram negative microbes, and preferably, lipopolysaccarhide at a... | 12/12/2006 |
| 7138124 | Polypeptides obtained from gram negative microbes The present invention provides compositions including at least two siderophore receptor polypeptides and at least two porins from a gram negative microbe, and preferably, lipopolysaccharide at a concentration of no greater than about 10.0 endotoxin units per millili... | 11/21/2006 |
| 7138125 | Methods for treating an animal for low milk production The present invention provides methods for treating an animal for low milk production. The methods include administering compositions including siderophore receptor polypeptides and porins from gram negative microbes, and preferably, lipopolysaccarhide at a concentr... | 11/21/2006 |
| 6984381 | Vaccine for the prevention of bacterial infection of the bovine mammary gland A novel vaccine for immunizing animals against Staphylococcus aureus-induced mastitis is disclosed. The vaccine is comprised of whole killed cells of S. aureus in a dosage effective to immunize an animal against the organism, in combination with a phar... | 01/10/2006 |
| 6936263 | Th1 inducing natural adjuvant for heterologous antigens The present invention relates to the use of the major OprI lipoprotein of Pseudomonas aeruginosa to elicit a Type-1 immune response towards a heterologous antigen. The invention relates specifically to the use of OprI—antigen fusion proteins to elicit the T... | 08/30/2005 |
| 6660262 | Broad spectrum antimicrobial compound and treatment A new and improved formulation and method for making same, for a broad spectrum antimicrobial treatment for bacterial and viral infections in cattle, horses, pigs, sheep and other domestic and non-domestic animals. More particularly, the present invention... | 12/09/2003 |
| 6432412 | Active immunization using a siderophore receptor protein The invention provides a vaccine for immunizing poultry and other animals against infection by a gram-negative bacteria, and a method of immunizing an animal using the vaccine. The vaccine may contain purified siderophore receptor proteins derived from a ... | 08/13/2002 |
| 6355255 | Streptococcal C5a peptidase vaccine Novel vaccines for use against ଲ-hemolytic Streptococcus colonization or infection are disclosed. The vaccines contain an immunogenic amount of a variant of strepococcal C5a peptidase (SCP). Also disclosed is a method of protecting a susceptible mam... | 03/12/2002 |
| 6287575 | Vaccine against papillomatous digital dermatitis (PDD) This invention relates to the diagnosis and prevention of ungulate diseases caused by the spirochete bacteria Treponema. The invention specifically relates to isolated cultures of this spirochete and isolated nucleic acids and proteins.... | 09/11/2001 |
| 6264952 | Method for protecting a mammalian host against infection by Brucella Vaccines against facultative intracellular pathogens are disclosed. A host is vaccinated with non-viable but metabolically active agents. The non-viable agents produce immunogenic components that elicit protective host immune responses, with minimal likel... | 07/24/2001 |
| 6241992 | Bovine footrot treatment and prevention This invention provides compositions and methods for treating or preventing footrot, in particular bovine footrot, by administering Porphyromonas and/or Prevotella and/or subunits and/or toxins thereof or neutralizing agents such as antibodies thereto. A ... | 06/05/2001 |
| 6096323 | Vaccine against papillomatous digital dermatitis (PDD) This invention relates to the diagnosis and prevention of ungulate diseases caused by the spirochete bacteria Treponema. The invention specifically relates to isolated cultures of this spirochete and isolated nucleic acids and proteins.... | 08/01/2000 |
| 6027736 | Active immunization using a siderophore receptor protein The invention provides a vaccine for immunizing poultry and other animals against infection by a gram-negative bacteria, and a method of immunizing an animal using the vaccine. The vaccine may contain purified siderophore receptor proteins derived from a ... | 02/22/2000 |
| 6019984 | Bacterial preparations, method for producing same, and their use as vaccines Novel bacterial preparations containing one or more isolated and purified strain of a microorganism which produces one or more RTX toxins, and which strain has at least one RTX toxin which is substantially cell-associated. Methods of preparing the bacteri... | 02/01/2000 |
| 5980908 | Bacterial cell surface protein with fibronectin, fibrinogen, collagen and laminin binding ability, process for the manufacture of the protein and prophylactic treatment The invention is concerned with a vaccine composition comprising an effective amount of an isolated protein derived from Staphylococcal aureus having the ability to bind fibronectin. The protein has a molecular weight of 165,000 daltons and optionally als... | 11/09/1999 |
| 5955090 | Immunogenic hybrid protein OprF-OprI derived from Pseudomonas aeruginosa membrane proteins The present invention relates to a hybrid protein comprising the Pseudomonas aeruginosa outer membrane protein I (OprI) which is fused with its amino terminal end to the carboxy-terminal end of a carboxy-terminal portion of the Pseudomonas aeruginosa oute... | 09/21/1999 |
| 5928649 | Method of reversing immunosuppression in vaccines A method of reversing or preventing immunosuppression or antigenic interference associated with combination vaccines in mammals, is disclosed. Cytokines, or cytokine inducer, are administered in conjunction with the combination vaccine. The cytokine or cy... | 07/27/1999 |
| 5855894 | Pasteurella haemolytica type A-1 bacterin-toxoid vaccine This invention relates to the field of Pasteurella haemolytica vaccines. More particularly, the invention relates to a bacterin-toxoid vaccine capable of inducing immunity in bovine species in one dose against Pasteurella haemolytica Type A-1 infection co... | 01/05/1999 |
| 5830479 | Active immunization using a siderophore receptor protein The invention provides a vaccine for immunizing poultry and other animals against infection by a gram-negative bacteria, and a method of immunizing an animal using the vaccine. The vaccine may contain purified siderophore receptor proteins derived from a ... | 11/03/1998 |
| 5718903 | Vaccine comprising Brucella abortus which has O polysaccharide antigen absent The present invention is an improved vaccine against Brucella abortus which permits differentiation between vaccinated and field strain infected cattle. The vaccine can be administered in two different forms: (1) cell envelopes isolated from an O polysacc... | 02/17/1998 |
| 5679349 | Vaccine design and production Peptides derived from proteins associated with bacterial adherence to mammary ductile epithelium are useful in vaccine preparation for preventing mastitis. Methods for determining Microbial adherence provide rational vaccine design.... | 10/21/1997 |
| 5637303 | Use of a phospholipase D mutant of Corynebacterium pseudotuberculosis for vaccination The present invention relates to a vaccine vector comprising a virulent corynebacterium or related organism which is incapable of expressing an active virulent factor or a non-virulent corynebacterium or related organism which synthesises an immuno protec... | 06/10/1997 |
| 5352448 | Oral administration of antigens An oral vaccine formulation is provided for stimulation of an immune response in gut-associated lymphoid tissues. The formulation comprises an enzymatically degradable antigen in a hydrogel matrix. In ruminant species, the vaccine formulation, upon oral a... | 10/04/1994 |
| 5336491 | Methods and compositions for the treatment and diagnosis of shipping fever Novel compositions are disclosed for use in the treatment or diagnosis of bovine pasteurellosis, commonly referred to as Shipping Fever. Cell-free Pasteurella haemolytica supernatants are employed to provide individual antigen compositions, identified thr... | 08/09/1994 |
| 5256415 | Vaccine against bovine respiratory disease (pasteurellosis) A vaccine against bovine respiratory disease is provided containing an attenuated strain of Pasteurella haemolytica isolated from an asymptomatic calf. The vaccine effectively triggers an immunological system response to whole cell, denuded, cytotoxin and... | 10/26/1993 |
| 5198214 | Anti-mastitis polyvalent vaccine, method of administration and method for production thereof A process for the production of a polyvalent vaccine effective in the prevention and treatment of mastitis in bovine animals is disclosed, which comprises periodically culturing the milk of animals exhibiting preclinical mastitis to cultivate any pathogen... | 03/30/1993 |
| 5198215 | Composition for controlling mastitis in ruminants, method for its preparation and method of treatment of ruminants The invention presents a composition for controlling mastitis in ruminants, a method for preparing the composition and a method of treatment of ruminants. The composition contains one or more soluble exoantigens of gram-positive bacteria involved in masti... | 03/30/1993 |
| 5165924 | Serum-free, cell-free vaccine effective against pneumonic pasteurellosis in cattle A serum-free vaccine effective against pneumonic pasteurellosis in cattle comprising a non-toxic leukotoxin specific for ruminant leukocytes is disclosed. The leukotoxin is prepared in a serum-free medium from a culture of Pasteurella haemolytica. The pro... | 11/24/1992 |
| 4840794 | Mastitis vaccine containing antigens from S. aureus A killed vaccine effective in the immunization of ruminants against intramammary challenge by S. aureus, comprises antiphagocytic in vivo antigen(s) produced by a pseudocapsule-producing strain of S. aureus. An in vitro method of cultivating S. aureus und... | 06/20/1989 |
| 4818528 | Vaccine against infectious bovine keratoconjunctivitis A vaccine for immunizing cattle against infectious bovine keratoconjunctivitis which contains protein fragments having an antigenic site common to pili of pathogenic strains of Moraxella bovis and is produced by reacting purified Moraxella bovis pili with... | 04/04/1989 |
| 4762712 | Anti-mastitis polyvalent vaccine, method of administration and method for production thereof A process for the production of a polyvalent vaccine effective in the prevention and treatment of mastitis in bovine animals is disclosed, which comprises periodically culturing the milk of animals exhibiting preclinical mastitis to cultivate any pathogen... | 08/09/1988 |
| 4675176 | Moraxella bovis protease vaccine Protease produced by Moraxella bovis can be used as an immunoprophylactic agent for protection against infection by M. bovis.... | 06/23/1987 |
| 4626430 | Processes for growth of modified Pasteurella haemolytica bacteria and preparation of a vaccine therefrom The chemical modification of virulent Pasteurella multocida and Pasteurella haemolytica strains and preparation of live bacteria vaccines from the modified organisms for immunization of bovine, porcine and ovine animal species are disclosed.... | 12/02/1986 |
| 4539201 | Medicament and method for inducing immunity to infectious bovine keratoconjunctivitis A medicament and method for inducing immunity in to infectious bovine keratoconjunctivitis in cattle. The medicament comprises the gram negative cocci Neisseria or Branhamella which are non-etiological agents of infectious Keratoconjunctivitis yet unexpec... | 09/03/1985 |
| 4440748 | Strain of Escherichia coli by bacterial conjugation A new strain of Escherichia coli which is enteropathogenic to both calves and piglets is produced by bacterial conjugation of two parents, one enteropathogenic solely to calves and one enteropathogenic solely to piglets. The new strain is useful in the pr... | 04/03/1984 |
| 4425330 | Bovine mastitis vaccine and method for detecting efficacy thereof This invention relates to a vaccine for the prevention and/or control of gram-positive cocci, e.g. Str. agalactiae and S. aureus, induced bovine mastitis infections and to an immunological method, an enzyme linked immunosorbent assay (ELISA), for assaying... | 01/10/1984 |
| 4388299 | Modified pasteurella bacteria and vaccines prepared therefrom The chemical modification of virulent Pasteurella multocida and Pasteurella haemolytica strains and preparation of live bacteria vaccines from the modified organisms for immunization of bovine, porcine and ovine animal species are disclosed.... | 06/14/1983 |
