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| Number | Title | Issue Date |
| 5128128 | Virus vaccine Provided are a virus vaccine, comprising a properly incapacitated virus lacking an antigen of the wild-type virus which is useful for serologically distinguished between vaccinated and infected animals, methods for distinguishing between vaccinated and in... | 07/07/1992 |
| 5128129 | Infectious bovine rhinotrachetis virus mutants, vaccines containing same, methods for the production of same and methods for the use of same Infectious bovine rhinotracheitis virus (bovine herpesvirus type 1) mutants containing deletion and/or insertion mutations in a major viral glycoprotein gene, such that no antigenic polypeptides encoded by the viral gene are produced, vaccines for infecti... | 07/07/1992 |
| 4824667 | Thymidine kinase deletion mutants of bovine herpesvirus-1, vaccines against infectious bovine rhinotracheitis containing same and methods for the production and use of same Bovine herpesvirus type 1 (infectious bovine rhinotracheitis virus) mutants which fail to produce any functional thymidine kinase as a result of a deletion in the thymidine kinase gene. The deletion in the thymidine kinase gene attenuates the viruses so t... | 04/25/1989 |
| 4753884 | Pseudorabies virus mutants, vaccines containing same, methods for the production of same and methods for the use of same The present invention relates to pseudorabies virus mutants containing deletion and/or insertion mutations in a major viral glycoprotein gene, such that no antigenic polypeptides encoded by the viral gene are produced. As a result, animals vaccinated with... | 06/28/1988 |
| 4722848 | Method for immunizing animals with synthetically modified vaccinia virus What are disclosed are methods for modifying the genome of vaccinia virus to produce vaccinia mutants, particularly by the introduction into the vaccinia genome of exogenous DNA; modified vaccinia prepared by such methods; certain DNA sequences and unmodi... | 02/02/1988 |
| 4703011 | Thymidine kinase deletion mutants of bovine herpesvirus-1 Bovine herpesvirus type 1 (infectious bovine rhinotracheitis virus) mutants which fail to produce any functional thymidine kinase as a result of a deletion in the thymidine kinase gene. The deletion in the thymidine kinase gene attenuates the viruses so t... | 10/27/1987 |
| 4680176 | Deletion mutant of a herpesvirus and vaccine containing said virus The invention relates to live deletion mutants of a herpesvirus, especially of Pseudorabies virus. The genomes of the mutants differ from the genomes of the parent strain by the presence of one or more deletions selected from a deletion in the inverted re... | 07/14/1987 |
| 4609548 | Vaccines for pseudorabies disease and methods for use of same Temperature-resistant pseudorabies viruses which fail to produce any functional TK as a result of mutagen-induced mutation and temperature-resistant pseudorabies viruses which fail to produce any functional TK as a result of a deletion in the tk gene, vac... | 09/02/1986 |
| 4569840 | Thymidine kinase-negative temperature resistant bovine herpesvirus-1 mutant as a vaccine against infectious bovine rhinotracheitis Described are thymidine kinase negative temperature resistant mutants of bovine herpesvirus effective in inducing resistance to infectious bovine rhinotracheitis, methods for their production, methods for maintaining them in viable form, and methods for a... | 02/11/1986 |
| 4514497 | Modified live pseudorabies viruses Temperature-resistant pseudorabies viruses which fail to produce any functional TK as a result of mutagen-induced mutation and temperature-resistant pseudorabies viruses which fail to produce any functional TK as a result of a deletion in the tk gene, vac... | 04/30/1985 |