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| Number | Title | Issue Date |
| 8187640 | Low viscosity liquid polymeric delivery system Low viscosity biodegradable polymer solutions of a liquid biodegradable polymer and biocompatible solvent and methods of using the compositions to form a biodegradable liquid polymer implant are provided. ... | 05/29/2012 |
| 8178131 | Pyrrolopyridines as kinase inhibitors Compounds of Formula (I) are useful for inhibition of CHK1 and/or CHK2. Methods of using compounds of Formula (I) and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders... | 05/15/2012 |
| 8097581 | Anti-wrinkle cosmetic composition The present invention relates to a composition for treating skin comprising an acylated short chain bioactive peptide and fulvic acid, and optionally colloidal gold. The invention further relates to a method for topically administering the composition in an amount t... | 01/17/2012 |
| 7951405 | Combined treatment with cisplatin and an epidermal growth factor receptor kinase inhibitor The present invention provides a method for treating tumors or tumor metastases in a patient, comprising administering to the patient simultaneously or sequentially a therapeutically effective amount of an EGFR kinase inhibitor and cisplatin combination, with or wit... | 05/31/2011 |
| 7838043 | Superoxide anion decomposing agent A scavenger of superoxide anion or nitric oxide comprising finepowder of a transition metal such as platinum. The scavenger is preferably provided as an aqueous solution containing transition metal colloid at a ratio of 1 mM or less per 1,000 ml, and can efficiently... | 11/23/2010 |
| 7820205 | Platinum colloid-containing aqueous solution for treating schizophrenia The present invention provides a composition comprising precious metal particles for treating or preventing a psychiatric symptom. The composition of the invention is able to improve various psychiatric symptoms and useful for treating or preventing psychiatric diso... | 10/26/2010 |
| 7803408 | Method of treating endothelial injury The use of human erythropoietin (EPO) to prevent or treat endothelial injury due to chemotherapy, radiation therapy, mechanical trauma, or to a disease state which damages the endothelium (such as inflammation, heart disease or cancer) is described. The use of EPO i... | 09/28/2010 |
| 7655261 | Medicament and method of treatment of patients with heavy metals A method of treatment of a diseased patient in which a dose of at least one heavy metal is delivered to the patient, with a surface area which is accessible for direct contact with the patient's tissue and effects release of heavy metal ions for uptake by immuno rea... | 02/02/2010 |
| 7611733 | Nanoparticle formulations of platinum compounds Solid Lipid Nanoparticles of platinum compounds, particularly of antitumor platinum complexes are disclosed. The Nanoparticles of the invention are obtained by a process comprising: a) preparing a first microemulsion by mixing a molten lipid, a surfactant, and optio... | 11/03/2009 |
| 7452554 | Platinum nanocolloid solution, process for producing the same and drink containing platinum nanocolloid A nanocolloidal platinum dispersion comprising nanocolloidal platinum and a polyacrylic acid salt, the nanocolloidal platinum having an average particle size of 1-5 nm, 90% or more of the nanocolloidal platinum having a particle size in a range of 0.1-10 nm, its pro... | 11/18/2008 |
| 7427416 | Methods of treating conditions using metal-containing materials Methods of treating conditions using metal-containing materials are disclosed. Exemplary conditions include bacterial conditions, biofilm conditions, microbial conditions, inflammatory conditions, fungal conditions, viral conditions, autoimmune conditions, idiopathi... | 09/23/2008 |
| 7422121 | Process for producing a sterilization system The invention relates to a method for producing a sterilisation system, especially for sterilising drinking water and water for industrial use. The precious metal surface of a base material containing precious metal is initially oxidised in an acidic solution and su... | 09/09/2008 |
| 7410655 | Anticancer agent An anticancer agent containing platinum preparation, humic substances, water and sodium chloride. Potassium tetrachloroplatinate is used as a platinum compound and lignohumic acid ammonium salts are used as humic substances taken in the following ratio of com... | 08/12/2008 |
| 7387790 | Pharmaceutical and diagnostic compositions containing nanoparticles useful for treating targeted tissues and cells Nanoparticles made from a select group of lipids and optionally containing a therapeutically active agent are employed in pharmaceutical compositions for delivery to targeted tissues and/or cells for the treatment or diagnosis of such diseases as cancer. ... | 06/17/2008 |
| 7371411 | Methods for production of the oxidized glutathione composite with CIS-diamminedichloroplatinum and pharmaceutical compositions based thereof regulating metabolism, proliferation, differentiation and apoptotic mechanisms for normal and transformed cells The present invention relates to a composite for the treatment of a variety of medical conditions, the composite comprising an oxidized glutathione-based compound, which has a disulfide bond, and a metal material, in particular where the metal is either platinum or ... | 05/13/2008 |
| 7367934 | Methods of enhancing radiation effects with metal nanoparticles The present invention provides methods of using metal nanoparticles 0.5 to 400 nm in diameter to enhance the dose and effectiveness of x-rays or of other kinds of radiation in therapeutic regimes of ablating a target tissue such as tumor. The metal nanoparticles can... | 05/06/2008 |
| 7357949 | Encapsulated inorganic antimicrobial additive for controlled release The invention relates to a microcapsule comprising an inorganic antimicrobial agent coated with a hydrophilic polymer. The hydrophilic polymer is able to absorb sufficient water as to enable the action of the encapsulated antimicrobial agent. These microcapsules are... | 04/15/2008 |
| 7354605 | Antimicrobial medical device According to the present invention there are provided antimicrobial catheters and other medical devices having controlled release of an antimicrobial metal or metal ion. Specifically, antimicrobial catheters and other medical devices manifest antimicrobial propertie... | 04/08/2008 |
| 7348310 | Synthetic methods for aplidine and new antitumoral derivatives, methods of making and using them The invention relates to aplidine derivatives of the general formula: which are useful for the treatment of tumors. ... | 03/25/2008 |
| 7345046 | Heteroaryl-fused pyrimidinyl compounds as anticancer agents Heteroaryl-fused pyrimidinyl compounds, pharmaceutically acceptable salts, and prodrugs thereof; compositions that include a pharmaceutically acceptable carrier and one or more of the heteroaryl-fused pyrimidinyl compounds, either alone or in combination with at lea... | 03/18/2008 |
| 7338940 | Cancer treatment including glycolytic inhibitors Glycolytic inhibitors are useful in the treatment of solid tumors by attacking anaerobic cells at the center on the tumor. 2-deoxyglucose, oxamate and various analogs thereof are identified as having a natural selective toxicity toward anaerobic cells, and will sign... | 03/04/2008 |
| 7323452 | Method for the accelerated in vivo removal of ethanol A method for accelerating the process of removing ethanol from the blood through the use of certain additives that accelerate the metabolic oxidation of ethanol, and others which in addition act as catalysts or “pseudo” enzymes for the oxidation. These additives... | 01/29/2008 |
| 7320713 | Treatment of fiber with water containing fine powder of noble metal dispersed therein A method of burning noble metals in high-pressure water using hydrogen and oxygen to produce noble metal micro-dispersion water in which super-fine noble metal particles are dispersed, and use the obtained noble metal micro-dispersion water to treat fiber products i... | 01/22/2008 |
| 7300672 | Titanium-group metal containing high-performance water, and its producing method and apparatus Produce titanium-group metal micro-dispersion water that contains ion vapor of titanium-group metal in micro-dispersed state and that can be used as a material for health products, medical products, cosmetics, etc., by using an apparatus comprising a water tank, a h... | 11/27/2007 |
| 7294332 | Combination therapy (temozolomide and α-IFN) for advanced cancer There is disclosed a method for treating advanced cancer in patients in need of such treating. Temozolomide and alpha interferon are administered in combination in amounts sufficient to achieve a clinical response. ... | 11/13/2007 |
| 7255881 | Metal-containing materials Metal-containing materials, as well as their preparation and use are disclosed. The metal-containing material can be, for example, an antimicrobial material, an anti-biofilm material, an antibacterial material, an anti-inflammatory material, an anti-fungal material,... | 08/14/2007 |
| 7238372 | Methods for inhibiting tumor cell proliferation The subject invention concerns methods for inhibition of STAT biological functions using platinum complexes. ... | 07/03/2007 |
| 7226608 | Topical use of microfine calcined alumina Dispersions containing from about 0.5% to about 30% by weight dispersed microfine calcined alumina, stainless steel, or gold particles typically having particle size of less than about 5μ, more narrowly 1μ or less, suspended in a cosmetically acceptable carrier ar... | 06/05/2007 |
| 7220428 | Pharmaceutical and diagnostic compositions containing nanoparticles useful for treating targeted tissues and cells Nanoparticles made from a select group of lipids and optionally containing a therapeutically active agent are employed in pharmaceutical compositions for delivery to targeted tissues and/or cells for the treatment or diagnosis of such diseases as cancer. ... | 05/22/2007 |
| 7205001 | Compositions and methods for the treatment of primary and metastatic neoplastic diseases using arsenic compounds The invention relates to the use of arsenic compounds to treat a variety of neoplastic diseases. The present invention encompasses the administration to a mammal of arsenic in the form of a salt, complex, organic compound or ionic solution to treat tumors of epithel... | 04/17/2007 |
| 7201925 | Treatment of ungual and subungual diseases The treatment of ungual and subungual diseases is disclosed. ... | 04/10/2007 |
| 7179493 | Compositions and methods for the treatment of primary and metastatic neoplastic diseases using arsenic compounds The invention relates to the use of arsenic compounds to treat a variety of neoplastic diseases. The present invention encompasses the administration to a mammal of arsenic in the form of a salt, complex, organic compound or ionic solution to treat tumors of epithel... | 02/20/2007 |
| 7175741 | Reducing odor in absorbent products Hydrogen sulfide is removed or reduced in absorbent products by the use of a particulate material attached to pulp fiber by a retention aid. The particulate material can remove or reduce the hydrogen sulfide in the environment surrounding the fiber. Suitable materia... | 02/13/2007 |
| 7169412 | Methods for production of the oxidized glutathione composite with cis-diamminedichloroplatinum and pharmaceutical compositions based thereof regulating metabolism, proliferation, differentiation and apoptotic mechanisms for normal and transformed cells The present invention relates to a composite for the treatment of a variety of medical conditions, the composite comprising an oxidized glutathione-based compound, which has a disulfide bond, and a metal material, in particular where the metal is either platinum or ... | 01/30/2007 |
| 7163703 | Compositions and methods for the treatment of primary and metastatic neoplastic diseases using arsenic compounds The invention relates to the use of arsenic compounds to treat a variety of neoplastic diseases. The present invention encompasses the administration to a mammal of arsenic in the form of a salt, complex, organic compound or ionic solution to treat tumors of epithel... | 01/16/2007 |
| 7138520 | Coordination complexes having tethered therapeutic agents and/or targeting moieties, and methods of making and using the same In part, the present invention is directed to coordination complexes comprising a therapeutic agent. In one aspect, the subject compositions comprise a platinum metal center and a covalently attached therapeutic agent. ... | 11/21/2006 |
| 7105492 | Camptothecin derivatives having antitumor activity Camptothecin derivatives of camptothecin of formula (I) exhibit antitumor activity and show a good therapeutic index and are used in the treatment of tumors, viral infections and antiplasmodium falciparum. ... | 09/12/2006 |
| 7097858 | Polyoxometalate materials, metal-containing materials, and methods of use thereof Polyoxometalate topical compositions for removing contaminants from an environment and methods of use thereof are disclosed. An embodiment of the polyoxometalate topical composition includes a topical carrier and at least one polyoxometalate, with the proviso that t... | 08/29/2006 |
| 7087249 | Treatment of mucosal membranes The invention relates to the use of one or more antimicrobial metals preferably selected from silver, gold, platinum, and palladium but most preferably silver, formed with atomic disorder, and preferably in a nanocrystalline form, for reducing inflammation or infect... | 08/08/2006 |
| RE39150 | Composition for creating vascular occlusions A composition including 2-hexyl cyanoacrylate and goal is useful in treating arteriovenous malformations (AVMs) and other body lumens to be blocked. ... | 06/27/2006 |