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| Number | Title | Issue Date |
| 7919121 | Biomaterial derived from vertebrate liver tissue A tissue graft composition comprising liver basement membrane and a method of preparation of this tissue graft composition are described. The graft composition can be implanted to replace or induce the repair of damaged or diseased tissues. ... | 04/05/2011 |
| 7771754 | Apparatus and methods for repairing tissue defects Methods and devices to process harvested skin tissue and reintroduction of the ground tissue to repair a tissue defect are disclosed. A hand-held portable tissue grinder comprising a housing and a grinding element are disclosed. The tissue grinder is used for grindi... | 08/10/2010 |
| 7754245 | Solid bio-material for a sensor that detects bio-electric signals through the use of the characteristics and functions of bio-epidermal tissues and epidermal tissues of living organisms and the methods for producing the same The present invention discloses a solid bio-material for the detection of a bio-electromagnetic signal, which senses an information signal generated from living organisms and changes thereof by using fish scale, feathers of fowl and carapaces of tortoises among epid... | 07/13/2010 |
| 7335382 | Compositions and methods for the treatment and prevention of cancer The present invention relates to new classes of anti-cancer agents. In particular, the present invention provides materials derived from natural sources as anti-cancer agents, alone, or in combination with other anti-cancer agents or therapies. ... | 02/26/2008 |
| 7316927 | Culture of goblet cells The invention encompasses isolation, culture and characterization of goblet cells in vitro from mammalian conjuctiva. Goblet cells can be cultured from conjunctiva of such mammals as, e.g., humans, rats, mice, rabbits and the like. In another aspect of the invention... | 01/08/2008 |
| 7232579 | Composition containing a marine-derived inorganic substance and chitin/chitosan, and method of producing the composition A composition contains an inorganic substance obtained as a residue after incinerating skins of marine organisms, and chitin/chitosan. The composition is obtained by incinerating the skins of the marine organisms at a temperature within a range between 600° C. and ... | 06/19/2007 |
| RE39337 | Nude mouse model for human neoplastic disease A nude mouse model for human neoplastic diseases having histologically intact human neoplastic tissue transplanted onto an organ of the mouse which corresponds to the human organ from which the tissue is obtained. ... | 10/10/2006 |
| 7052856 | NELL-1 enhanced bone mineralization This invention pertains to the discovery that the human NELL-1 gene induces or upregulates bone mineralization. The NELL-1 gene or gene product thus provides a convenient target for screening for modulators of bone mineralization. In addition, NELL-1 can be used to ... | 05/30/2006 |
| 7052690 | Culture of goblet cells The invention encompasses isolation, culture and characterization of goblet cells in vitro form mammalian conjuctiva. Goblet cells can be cultured from conjunctiva of such mammals as, e.g., humans, rats, mice, rabbits and the like. In another aspect of the invention... | 05/30/2006 |
| 6962775 | Wound repair dressings and methods for their preservation Methods and products relating the preservation of cultured mammalian epithelial or mesenchymal cells are provided. The methods involve the pre-treatment of epithelial cells with a solution containing a cryoprotectant amount of monosaccharides and/or disaccharides. T... | 11/08/2005 |
| 6955924 | Laminin chains: diagnostic uses The instant invention provides for the identification, diagnosis, monitoring, and treatment of invasive cells using the laminin 5 gamma-2 chain protein or nucleic acid sequence, or antibodies thereto. ... | 10/18/2005 |
| 6946145 | Block copolymers based on poly(ortho esters) containing amine groups Block copolymers based on poly(ortho esters) containing amine groups. These block copolymers have both hydrophilic and hydrophobic blocks. They form micelles in aqueous solution, making them suitable for encapsulation or solubilization of hydrophobic or water-insolu... | 09/20/2005 |
| 6919309 | Methods and compositions for inhibiting angiogenesis The present invention provides a method of inhibiting angiogenesis within a tissue by providing exogenous PEDF to cells associated with the tissue. The presence of exogenous PEDF inhibits angiogenesis within the tissue, in part by interfering with the ability of vas... | 07/19/2005 |
| 6610538 | Reconstructed laminae of human epithelium corneae and method of producing the same A method of reconstructing laminae of human epithelium corneae in vitro to be used in grafts from cultures of limbar stem cells as well as a method of selecting and transferring such cells to fibrin substrate.... | 08/26/2003 |
| 6582730 | Natural fluorescent dye obtained from a marine invertebrate, compositions containing the said dye and their uses The present invention discloses the process of extraction, purification and characterization of a fluorescent dye from a marine echinoderm Holothuria scabra, compositions containing the dye and various applications of the dye.... | 06/24/2003 |
| 6562377 | Composition to stop hairloss A composition to stop hair-loss and a method of making said composition with a base of paraffin oil, pure alcohol and fur of otters or minks. This composition is oily and is applied on the part of the head which suffers from hair falling. The remaining on... | 05/13/2003 |
| 6558949 | Media for culturing human cells comprising human serum and method for culturing human cells using the same This invention relates to media for culturing human cells that the proliferation speed of human cells is increased and the cell expression type is stably manifested, and to a method for culturing human cells using the same. This invention is characterized... | 05/06/2003 |
| 6544946 | Inhibitors for use in hemostasis and immune function The present invention relates to polynucleotide and polypeptide molecules for use as inhibitors in hemostasis and immune function. Such inhibitors are members of the family of proteins bearing a collagen-like domain and a globular domain. The inhibitors a... | 04/08/2003 |
| 6541519 | Methods and compositions for treating lipoxygenase-mediated disease states Methods and compositions are disclosed for prevention and/or treatment of diseases in which 5- and 12-lipoxygenase activity contributes to the pathological condition, by administration of 12-methyletradecanoic acids alone and in conjunction with other the... | 04/01/2003 |
| 6440935 | Inhibition of eucaryotic pathogens and neoplasms and stimulation of fibroblasts and lymphocytes with lytic peptides Inhibition of eucaryotic pathogens and neoplasms and stimulation of lymphocytes and fibroblasts with lytic peptides such as cecropins and sarcotoxins. Eucaryotic cells are contacted with cecropin or sarcotoxin, or a synergistic combination of cecropins or... | 08/27/2002 |
| 6391850 | Methods and compositions for inhibiting angiogenesis The present invention provides a method of inhibiting angiogenesis within a tissue by providing exogenous SLED to cells associated with the tissue. The presence of exogenous SLED inhibits angiogenesis within the tissue, in part by interfering with the abi... | 05/21/2002 |
| 6288024 | Methods and compositions for inhibiting angiogenesis The present invention provides a method of inhibiting angiogenesis within a tissue by providing exogenous SLED to cells associated with the tissue. The presence of exogenous SLED inhibits angiogenesis within the tissue, in part by interfering with the abi... | 09/11/2001 |
| 6270756 | Weight loss induced by alpha interferon and gamma interferon The invention is based on the discovery that substances which release ZAG proteins from lymphocytes also cause accelerated weight loss in humans. By administering an amount of the substance which is effective to cause the weight loss but is beneath an amo... | 08/07/2001 |
| 6231879 | Biocompatible devices with foam scaffolds This invention is directed to methods of manufacturing implantable biocompatible cell encapsulation devices, wherein the cell encapsulation devices have a jacket made of a permeable, biocompatible material that is loaded with a core made of a reticulate f... | 05/15/2001 |
| 6200606 | Isolation of precursor cells from hematopoietic and nonhematopoietic tissues and their use in vivo bone and cartilage regeneration The present invention relates to the isolation of cartilage or bone precursor cells from hematopoietic and non-hematopoietic cells and their use in bone and cartilage regeneration procedures. The precursor cells are used for in vivo bone or cartilage repa... | 03/13/2001 |
| 6054142 | Biocompatible devices with foam scaffolds A biocompatible cell device having an internal foam scaffold to provide a growth surface for encapsulated cells which produce a biologically active molecule.... | 04/25/2000 |
| 5989592 | Inhibition of complement pathway by sea cucumber fractions The present invention relates to methods for inhibiting the complement pathway in a mammal comprising administering an effective dose of a composition comprising an active ingredient selected from the group consisting of isolated sea cucumber (Phylum Echi... | 11/23/1999 |
| 5985330 | Inhibition of angiogenesis by sea cucumber fractions The present invention provides inhibition of angiogenesis in a warm-blooded animal by the administration of preparations isolated from the echinoderm sea cucumber (Class Holothuroidea). This preparation is useful as a therapeutic agent against malignant t... | 11/16/1999 |
| 5962325 | Three-dimensional stromal tissue cultures The present invention relates to a method of stimulating the proliferation and appropriate cell maturation of a variety of different cells and tissues in three-dimensional cultures in vitro using TGF-ଲ in the culture medium. In accordance with the i... | 10/05/1999 |
| 5945101 | Skin model system This invention relates to a skin model system that can be used as an in vitro test system or which can be used for therapeutic purposes. The skin model system comprises a three-dimensional, cross-linked matrix of insoluble collagen containing fibroblast c... | 08/31/1999 |
| 5912018 | Methods for treatment of muscle spasm, edema and dermatological conditions using epidermal gel secretion from an arabian gulf catfish The present invention provides an epidermal gel secretion of Arabian Gulf catfish which is useful in enhancing wound healing, alleviating muscle spasms and pain, and treating dermatological disorders.... | 06/15/1999 |
| 5902741 | Three-dimensional cartilage cultures The present invention relates to a method of stimulating the proliferation and appropriate cell maturation of a variety of different cells and tissues in three-dimensional cultures in vitro using TGF-ଲ in the culture medium. In accordance with the i... | 05/11/1999 |
| 5834027 | Injection of rhea and ostrich oils in animals A method of treating animals, particularly rhea and ostrich chicks with adipose depletion, by injection with an oil derived from rhea or ostrich adipose or by injection with an active component of the oil that increases anti-inflammatory capabilities and ... | 11/10/1998 |
| 5830507 | Biotherapeutic cell-coated microspheres A living skin replacement for the treatment of partial-thickness and full-thickness skin injuries, such as burns and other wounds, consists of a slurry of cell-coated microspheres which can be applied to the skin injury in much the same manner as a paste ... | 11/03/1998 |
| 5811632 | Non-human mammalian model for human papillomavirus-induced disease A method for producing a mammalian model for papillomavirus infection by engrafting a portion of human skin onto a transplant-tolerant non-human mammal, inoculating the engrafted human skin with a papillomavirus genomic DNA such that a papillomavirus infe... | 09/22/1998 |
| 5783408 | Method for screening potential anti-obesity agents A method for screening a compound as a potential anti-obesity agent by determining whether the compound stimulates micro motion of cells in vitro is described... | 07/21/1998 |
| 5756094 | Methods for stimulating follicular growth A method of modulating hair growth by contacting selected cells with a selected growth-modulating molecule is provided. A method for hair reconstitution or transplantation by expanding selected cells in vitro and combining them with other cells that regul... | 05/26/1998 |
| 5698228 | Wound healing composition using squid chitin and fish skin collagen There is provided a skin substitute that can suitably be used for covering the surface of a damaged skin area which is typically a wound produced by a traumatic local loss of the skin of the human body as a result of a burn or some other cause of damage. ... | 12/16/1997 |
| 5688531 | Method for regulating bone forming cells Regulation factors and a method for modulating bone forming cells including the steps of collecting regulation factors from bone stromal cells including marrow adipocytes and treating the bone forming cells with the regulation factors derived from stromal... | 11/18/1997 |
| 5681561 | Compositions and methods for improving autologous fat grafting The present invention relates to compositions and methods for enhancing the success of autologous fat grafting in a patient. The compositions according to the present invention are useful for enhancing autologous fat grafting by improving the survival rat... | 10/28/1997 |
