...that the video game, Pong, was invented by a guy who graduated at the bottom of his engineering class? Nolan Bushnell spent more time running the games at a local amusement park than he did on his studies at the University of Utah. His dreams of working for Disney's amusement empire were dashed when the company wouldn't hire him. Taking a boring job, Nolan daydreamed about electronic versions of popular games. He invented Pong, the first video game, and went on to found Atari Co.
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| Number | Title | Issue Date |
| 8178130 | Preservation and controlled delivery / release of spermatozoa The present invention relates to biopolymer particles for preservation of spermatozoa, wherein the spermatozoa are embedded within the biopolymer particle. The present invention also regards a method for preservation, storage and controlled delivery/release of sperm... | 05/15/2012 |
| 7371517 | High purity X-chromosome bearing and Y-chromosome bearing populations of spermatozoa Isolated non-naturally occurring populations of spermatozoa (15) having high purity and technologies to differentiate spermatozoa (28) based on characteristics such as mass, volume, orientation, or emitted light including methods of analysis and appara... | 05/13/2008 |
| 7335507 | Process for the staining of sperm Sperm cells are stained according to processes that involve the combining of sperm cells with a fluorescent DNA selective dye at an elevated temperature in excess of about 40° C. The methods allow for a decreased staining time. The cells may thereafter be efficient... | 02/26/2008 |
| 7208265 | Method of cryopreserving selected sperm cells The present invention provides a method of cryopreserving sperm that have been selected for a specific characteristic. In a preferred embodiment, the method is employed to freeze sex-selected sperm. Although the cryopreservation method of the invention can be used t... | 04/24/2007 |
| 7204978 | Treatment and diagnosis of infertility using TGFβ or activin A method of treating an infertility condition in humans or mammals, by exposure of a prospective mother to TGF beta or derivative or analog of TGF beta. The exposure is advantageously in conjunction with one more antigens of a prospective father so that a hyporespon... | 04/17/2007 |
| 7195920 | Collection systems for cytometer sorting of sperm Improved flow cytometer system particularly adapted to use for sex-selected sperm sorting include enhanced sheath fluid and other strategies which minimize stress on the sperm cells, including a 2.9 percent sodium citrate sheath solution for bovine species and a HEP... | 03/27/2007 |
| 7169548 | Sperm cell processing and preservation systems Methods and apparatus are disclosed for processing sperm cells to accomplish preservation for future use while minimizing the adverse effects of such preservation. Sperm cells may be collected from a male animal and subjected to a first preservation step, including ... | 01/30/2007 |
| 7163919 | Anticancer composition The present invention relates to an anticancer composition comprising a therapeutically effective amount of one or more active components selected from the group consisting of citric acid; citric acid and zinc; citric acid and albumin; and citric acid, zinc and albu... | 01/16/2007 |
| 7094527 | System for in-vitro fertilization with spermatozoa separated into X-chromosome and Y-chromosome bearing populations An IVF system for successfully utilizing spermatozoa separated into X-chromosome bearing and into Y-chromosome bearing population for insemination. The IVF system includes fertilization medium that can shorten the time from insemination to cleavage and a portable in... | 08/22/2006 |
| 7087429 | Process for proliferation and differentiation of rat ascinar cells A process for obtaining a substance with growth promoting activity that includes the step of isolating perivitelline fluid from a fertilized egg of a horseshoe crab. Also, a process for proliferating cells including the steps of isolating perivitelline fluid from a ... | 08/08/2006 |
| 7074983 | Transgenic bovine comprising human immunoglobulin loci and producing human immunoglobulin The present invention relates to the production of a transgenic bovine which comprises a genetic modification that results in inactivation and loss of expression of its endogenous antibodies, and the expression of xenogenous antibodies, preferably human antibodies. ... | 07/11/2006 |
| 7024316 | Transiently dynamic flow cytometer analysis system A flow cytometry apparatus and methods to process information incident to particles or cells entrained in a sheath fluid stream allowing assessment, differentiation, assignment, and separation of such particles or cells even at high rates of speed. A first signal pr... | 04/04/2006 |
| 7011853 | Putamen ovi The present invention pertains to a method for the preparation of putamen ovi, putamen ovi having a defined grain size distribution, and to the use of putamen ovi for the treatment of calcium deficiency and other disease conditions. ... | 03/14/2006 |
| 6890708 | Method for improving the quality of sperm for artificial insemination of animals A method and composition for artificial insemination. The method involves artificially inseminating the subject with sperm, wherein the sperm is combined or coadministered with an inhibitor of phosphodiesterase and preferably a soluble salt of an earth alkaline meta... | 05/10/2005 |
| 6864046 | Method for collecting and preserving semen A method for collecting and preserving semen of various animals including humans, canines, porcines, bovines, ovines and others involves collecting the semen into a collection vessel where the collection vessel is provided with an extender solution for the semen pri... | 03/08/2005 |
| 6793923 | Vaccines with enhanced immune response and methods for their preparation The present invention is concerned with vaccines and their preparation. An effective long-term immune response, especially in mammals, can be produced using a vaccine comprising an antigen encapsulated in liposomes, a suitable adjuvant and a carrier comprising a con... | 09/21/2004 |
| 6641526 | Development of normal offspring from oocytes injected with freeze-dried spermatozoa The invention provides a method for freeze-drying spermatozoa to obtain at least one reconstituted spermatozoon whose head (nucleus) is capable of fertilizing an oocyte to produce a live offspring. The motility of spermatozoa which have been freeze-dried ... | 11/04/2003 |
| 6596472 | Reproductive cultures containing colloidal silver A colloidal dispersion of nanoparticles of silver is used to preserve animal reproductive samples such as boar semen without the use of antibiotics. The colloidal silver solution may have a metal concentration of at least about 1×10-9 moles/liter and may... | 07/22/2003 |
| 6596310 | Method of artificial insemination by timed release of sperm from capsules or solid beads A method is provided for encapsulating sperm in a particle wherein the particle provides for the timed release of the sperm. In particular, the method uses a gel forming polymer to form the particle and a medium for maintaining most of the sperm in a non-... | 07/22/2003 |
| 6506570 | Method of sorting birds in ovo A method of determining the gender of a bird in ovo comprises detecting the presence or absence of an elevated level of a sex-related hormone in the extra-embryonic fluid of the bird egg, and then determining the gender of the bird within the egg from the... | 01/14/2003 |
| 6361934 | Method and apparatus for cryopreservation A method of cryopreserving biological material, which method comprises providing a sample of the biological material, where a liquid phase of the sample includes at least one solute; lowering the temperature of the sample to a nucleating point at which ic... | 03/26/2002 |
| 6086884 | Composition for treating impotence in men containing dried roe and yohimbine A composition for treating impotence in human males contains a synergistic mixture of dried sturgeon roe and yohimbine hydrochloride wherein the weight percent ratio of said dried sturgeon roe:yohimbine hydrochloride is from about 25:1 to 1000:1, with an ... | 07/11/2000 |
| 6054142 | Biocompatible devices with foam scaffolds A biocompatible cell device having an internal foam scaffold to provide a growth surface for encapsulated cells which produce a biologically active molecule.... | 04/25/2000 |
| 6004586 | Molecule involved in binding of sperm to egg surfaces and procedures for use of this molecule to enhance or decrease potential fertility A purified polypeptide which provides for initial binding of sperm to oocyte investments and has an active amino acid sequence of SEQ ID NO:12 (Cys-Gln-Ser-Leu-Gln-Glu-Tyr-Leu-Ala-Glu-Gln-Asn-Gln-Arg-Gln-Leu-Glu-Ser-A sn-Lys-Ile-Pro-Glu-Val-Asp-Leu-Ala-Arg... | 12/21/1999 |
| 5997909 | Composition containing a complex of a polyvalent metal and a DNA-sodium salt Compositions are provided which contain a complex of a polyvalent metal and sodium salt, the DNA-sodium salt being obtained from sturgeon milt. The complexes exhibit high antiviral activity and low toxicity.... | 12/07/1999 |
| 5985333 | Pharmaceutical formulation containing a DNA-sodium salt for burn and wound treatment A pharmaceutical composition is provided for the treatment of burns and wounds and contains a DNA-sodium salt obtained preferably from sturgeon milt. This composition is particularly useful for the treatment of burns resulting from radiation.... | 11/16/1999 |
| 5972592 | Increasing reproductive efficiency of bull semen using fucose or a compound with a fucose moiety Inclusion of fucose or fucose-containing bull sperm monovalent binding oligosaccharide in semen extender increases the reproductive efficiency of bull semen extended therewith, for artificial insemination of cows by increasing non-return rates for normal ... | 10/26/1999 |
| 5849473 | Method of lyophilization of mammalian sperm cells A method is provided for the lyophilization of mammalian sperm cells which can be stored and reconstituted to provide morphologically intact cells. The method is advantageous in that the sperm cells may be stored at ambient temperatures for extended perio... | 12/15/1998 |
| 5773217 | Activation of sperm nuclei and activation assays The present invention concerns products and methods particularly useful for activating and analyzing non-dividing cell nuclei. The featured products include activating egg extracts, cytostatic factor (CSF) extracts, kits containing these extracts, and a m... | 06/30/1998 |
| 5763206 | Process for evaluating fertility of spermatozoa samples A method for testing the potential fertility of spermatozoa in a sample by contacting an aliquot of the sperm sample onto a protein extracted from native vitelline membranes removed from chicken or turkey eggs to enable quantification of the number of spe... | 06/09/1998 |
| 5759763 | Method for cryopreservation of primordial germ cells and germ cells Cryopreservation of primordial germ cells and germ cells, in which primordial germ cells or germ cells are separated from bird embryos before meiosis and are then suspended and frozen in a freezing medium containing a cryoprotective agent is useful for th... | 06/02/1998 |
| 5736141 | Method to prevent fertilization in mammals by administering a single dose of zona pellucida derived antigens, liposome and Freund's adjuvant A vaccine for the immunocontraception of mammals is described. The vaccine consists of zona pellucida antigens and an adjuvant encapsulated in a liposome delivery system. The liposome delivery system allows for the slow release of antigen resulting in a p... | 04/07/1998 |
| 5730987 | Medication for impotence containing lyophilized roe and a powdered extract of Ginkgo biloba A composition for treating impotence in human males is disclosed, which includes a mixture of lyophilized roe and a dry powdered extract from leaves of Ginkgo biloba. The lyophilized roe is obtained from a species of Sturgeon. The dry powdered extract is ... | 03/24/1998 |
| 5721348 | DNA encoding PH-20 proteins The disclosure relates to isolated DNA encoding all or a portion of a surface protein present in sperm of a mammal. This surface protein of sperm is essential for fertilization in the mammal. Preferably, the sperm surface protein is the PH-20 protein.... | 02/24/1998 |
| 5662889 | Oral Composition containing a DNA-sodium salt and methods of making and using the same Oral compositions for use in the mouth are provided which contain a DNA-sodium salt obtained preferably from sturgeon milt. The compositions are useful, for example, as mouth wash and toothpaste formulations.... | 09/02/1997 |
| 5648468 | Process for identifying sex associated egg proteins and methods for increasing the probability that the avian offspring will be the desired sex A method for Avian sex-preselection by identifying sex-specific proteins for maternal immunization to embryonic proteins is described. Sex-preselection proteins are used in sexing offsprings.... | 07/15/1997 |
| 5637300 | Contraceptive vaccine comprising a glycosylated 55 kD zona pellucida protein immunogen and method of use of the same in contraception Recombinant zona pellucidae proteins having altered, non-native glycosylation patterns are able to elicit the production of antibodies to matured zona pellucida proteins. Such recombinant proteins and the elicited antibodies can therefore be used in a con... | 06/10/1997 |
| 5580547 | Stimulation of tanning by DNA fragments or single-stranded DNA A method of increasing pigmentation in mammalian skin, as well as protecting mammalian skin against ultraviolet damage, is disclosed. Also disclosed is a method of increasing pigmentation in mammalian cells, as well as a method of enhancing melanin produc... | 12/03/1996 |
| 5563059 | Use of human inhibin and human activin to increase the number of mature primate oocytes A method is provided for increasing the fertilization potential of oocytes comprising culturing oocytes in vitro with an effective amount of inhibin, activin, or a combination of inhibin and activin. Preferably the oocytes being cultured are immature. Aft... | 10/08/1996 |
| 5547684 | Cosmetic composition containing a DNA-sodium salt and methods of making and using the same Cosmetic preparations are provided containing a DNA-sodium salt and which are useful, for example, for the treatment of aging skin and skin problems.... | 08/20/1996 |