Class 424/556 - Pancreas

Subclass of Class 424 - Drug, bio-affecting and body treating compositions
Definition: Subject matter in which the material is or is derived from
No. of patents: 29
Last issue date: 03/28/2006

Number	Title	Issue Date
7018419	Microporous encapsulated endocrine cell disks, biconcave disks and multidimpled chambers for hormonal replacement An endocrine cell microdisk or macrodisk containing pancreatic cells for transplantation into an animal body is formed with a lateral extent much greater than its thickness to thereby enhance its diffusional capability. One or more concavities may also be formed the...	03/28/2006
6207159	Methods for the diagnosis and treatment of insulin-dependent diabetes mellitus Methods for detecting the status of an insulin-dependent diabetes mellitus (IDDM)-associated autoimmune response in a mammal are provided. Specifically, the ratio of the frequency of T helper 1 cells to T helper 2 cells specific for a pancreatic ଲ-c...	03/27/2001
6054142	Biocompatible devices with foam scaffolds A biocompatible cell device having an internal foam scaffold to provide a growth surface for encapsulated cells which produce a biologically active molecule....	04/25/2000
5993806	Method of stabilizing pharmaceutical preparations comprising digestive enzyme mixtures The use of complex lipids, especially lecithin, as additives to stabilize water-soluble pharmaceutical preparations of digestive enzyme mixtures containing lipases and proteases, especially pancreatin-containing digestive enzyme mixtures, which are suitab...	11/30/1999
5895652	Method of metabolic adjuvanation and cellular repair A multi-agent tri-daily comestible of vitamin, mineral, plant extracts, aminos, neurochemical precursors, enzymes, and Ph regulating agents which supply key elements necessary for proper metabolization and function of the human body delivered at specific ...	04/20/1999
5888514	Natural composition for treating bone or joint inflammation A composition for treating a mammal having a condition characterized by bone or joint inflammation comprises: 2,250 mg soluble bovine cartilage, 250 mg soluble shark cartilage, 1,000 mg glucosamine sulfate, 350 mg mucopolysaccharide concentrate, 225 mg proteolytic ...	03/30/1999
5833979	Methods and compositions of growth control for cells encapsulated within bioartificial organs This invention relates to methods and compositions of controlling cell distribution within a bioartificial organ by exposing the cells to a treatment that inhibits cell proliferation, promotes cell differentiation, or affects cell attachment to a growth s...	11/10/1998
5691448	Reagents and methods for the diagnosis and treatment of diabetes and stiff man syndrome The invention provides fragments of GAD65 that are specifically reactive with at least one class of GAD65 autoantibody. Most fragments are substantially free of N-terminal amino acids that would otherwise limit solubility. Different ...	11/25/1997
5681587	Growth of adult pancreatic islet cells A method of increasing the number of adult pancreatic islet cells available for transplantation by contacting the cells with laminin 5 extracellular matrix. When contacted with the deposited matrix produced by 804G rat bladder carcinoma cells, a 1,500 fol...	10/28/1997
5672361	Laminin 5 for growth of pancreatic islet cells A method of expanding the number of pancreatic islet cells for transplantation. Fetal islet cells are cultured in the presence of laminin 5 extracellular matrix, resulting in a significant increase in cell number after passaging in culture. The expanded i...	09/30/1997
5639467	Electrostatic process for manufacturing coated transplants and product An electrostatic process for coating a biological material with a uniform, continuous polymer layer by discharging a suspension of the biological material in a gellable coating polymer solution in a continuous stream through an orifice. The stream is atte...	06/17/1997
5491284	Nude mouse model for neoplastic disease A nude mouse model for human neoplastic disease having histologically intact human neoplastic tissue transplanted onto an organ of the mouse which corresponds to the human organ from which the tissue is obtained....	02/13/1996
5470731	Coated transplant and method for making same Transplants are coated with an insoluble immunological barrier membrane. The membrane can comprise a non-cytotoxic first layer of agarose and cationic amino acid polymer and a non-cytotoxic second layer chemically bonded to said first layer, the second la...	11/28/1995
5190041	System for monitoring and controlling blood glucose Systems are disclosed which utilize implanted glucose sensitive living cells to monitor blood glucose levels. The implanted cells produce a detectable electrical or optical signal in response to changes in glucose concentration in surrounding tissue. The ...	03/02/1993
5175004	Propagatable, new combinant cells for cellular replacement therapy A method for creating a propagatable, new combinant cell with differentiated function to replenish dwindling number of similar cells in diseased subjects. The new combinant cell is obtained by 1) removing a nucleated cell, which is of the same differentia...	12/29/1992
5145679	Topical emollient for prevention and treatment of circulatory induced lesions A topical emollient for the treatment of circulation induced lesions comprises a source of glucose and insulin. The topical emollient is utilized in a process wherein the emollient is applied to the affected surface for nourishment thereof and promotion o...	09/08/1992
5093317	Treating disorders by application of insulin-like growth factor Method of enhancing the survival of neuronal cells, more preferably non-mitotic neuronal cells and/or cholinergic cells in a mammal, which cells are at risk of dying, which method includes administering to the mammal an effective amount of a functional de...	03/03/1992
5032408	Composition for treatment of skin affections and process for its preparation The invention is directed to a composition of skin disorders, such as cellulites or striae, comprising an oily fraction of paraffinic oils, an emulsifier, predominantly consisting of a) mono- and/or diglycerides of higher unsaturated natural fatty acids, and b) eth...	07/16/1991
4902295	Transplantable artificial tissue A transplantable artificial tissue matrix structure containing viable cells which is suitable for insertion into the body is made by polymerizing precursors in an aqueous solution to form a shape retaining solid matrix comprising viable cells, matrix poly...	02/20/1990
4868121	Islet isolation process A method of producing intact islets of Langerhans in an insulin producing condition uses a mixture of Hank's solution and 10% by volume fetal calf serum to ductally distend the human pancreas. The exocrine tissue of the pancreas is digested at about 37° ...	09/19/1989
4689293	Microencapsulation of living tissue and cells Living tissue or cells, for example, islets of Langerhans, are microencapsulated for implantation in the body for long term treatment of diabetes or other disease requiring organ transplantation. The microcapsules take the form of a biocompatible semi-per...	08/25/1987
4673566	Microencapsulation of living tissue and cells Living tissue or cells, for example, islets of Langerhans, are microencapsulated for implantation in the body for long term treatment of diabetes or other disease requiring organ transplantation. The microcapsules take the form of a biocompatible semi-per...	06/16/1987
4663163	Modified polysaccharide supports A modified polysaccharide material which comprises: (1) polysaccharide covalently bonded to a synthetic polymer; (2) the synthetic polymer being made from (a) a polymerizable compound which is capable of being covalently coupled directly or indirectly to ...	05/05/1987
4485096	Tissue-equivalent and method for preparation thereof A tissue-equivalent, useful in the treatment of burns or other skin wounds and in the fabrication of prostheses, is disclosed which is prepared from a hydrated collagen lattice contracted by a contractile agent, such as fibroblast cells or blood platelets...	11/27/1984
4405608	Novel peptide A novel, purified peptide having the following amino acid sequence: Arg-Ser-Leu-Gln-Asn-Thr-Glu-Glu-Lys-Ser-Arg-Ser-Phe-Pro-Ala-Pro-Gln-Thr-Asp -Pro-Leu-Asp-Asp-Pro-Asp-Gln-Met-Thr-Glu-Asp. The peptide may be used as medicament, e.g., in the treatment of gastro...	09/20/1983
4298002	Porous hydrophilic materials, chambers therefrom, and devices comprising such chambers and biologically active tissue and methods of preparation Hydrophilic polymeric chambers for encapsulating biologically active tissue and methods for their preparation. The tissue refers to those essential cellular components of a particular organ that is capable of receiving, modifying or secreting hormones. A ...	11/03/1981
3962425	Ruminant repellent from enzymatically putrefied lipoidal material A ruminant repellent composition effective to discourage browsing of edible material, especially living vegetable matter, is the decomposition product of a lipoidal material admixed with a lipolytic enzyme. One such composition is produced by admixing fis...	06/08/1976
3944665	Novel biologically-active compounds and method for isolating them from raw materials containing insulin The biologically-active compounds disclosed herein are two low-molecular water-soluble compounds that are formed in the incretory apparatus of the pancreas, which exhibit a coronary dilating effect and which are characterized by the following physico-chem...	03/16/1976
3936351	Method for preparing glucoronyl-glucosamino-glycan sulphates exhibiting antilipasaemic activity Method for preparing glucuronyl-glucosamino-glycan sulphates exhibiting antilipasaemic activity, according to which the duodenum of pancreas of animals are subjected to a hydrolysis, the liquid is removed, precipitation is carried out with a quaternary am...	02/03/1976

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Class 424/556 - Pancreas