...Chester Carlson was a patent agent who tired of having to make multiple copies of patent applications using the only duplication method available at the time: carbon paper. In 1959 he came up with a new copying system and took it to IBM for evaluation. The "experts" at IBM determined potential sales to be only 5,000 units because people wouldn't want to use a bulky machine when they had carbon paper. Carlson's invention was the xerography process, the company founded on the system is Xerox.
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| Number | Title | Issue Date |
| 4844907 | Pharmaceutical composition comprising analgesic and anti-inflammatory agent A pharmaceutical composition in the form of a multiphase (especially a bilayered, optionally coated) tablet. The tablet has a narcotic analgesic phase containing a therapeutically effective quantity of a narcotic analgesic or an analgesically effective sa... | 07/04/1989 |
| 4837030 | Novel controlled release formulations of tetracycline compounds Pharmaceutical compositions comprising spherical granules including thereon or therein a 7- or 9-akylamino-6-deoxy-6-demethyltetracycline or an acid-addition salt thereof blended with at least one excipient are adapted to control the rate of drug release ... | 06/06/1989 |
| 4818542 | Porous microspheres for drug delivery and methods for making same Controlled release drug delivery systems comprised of spherical microporous polymeric network of interconnecting channels containing pore incorporated drugs or other agents wherein the drugs or agents are confined within the pore channel are described. Al... | 04/04/1989 |
| 4774083 | Novel pharmaceutical tablets Novel tablets comprising (a) 80 to 98% by weight of a mixture of trimethoprim and/or an acid addition salt thereof and a sulfonamide and/or a salt thereof in a weight ratio of 1:20 to 20:1 and (b) a pharmaceutically acceptable synthetic ion exchange resin... | 09/27/1988 |
| 4769236 | Medicaments with a high degree of solubility and method for their production The present invention relates to medicaments with a high degree of dissolution rate and solubility. These medicaments are characterized in that they are in amorphous form produced by spraying in the presence of a stabilizer and of an agent inhibiting the ... | 09/06/1988 |
| 4764380 | Drug delivery system comprising a volume increasing matrix containing a plurality of tiny pills A delivery device is disclosed for delivering a beneficial drug to a biological environment of use. The device comprises a hydrogel reservoir containing tiny pills. The tiny pills comprise a wall surrounding a drug core.... | 08/16/1988 |
| 4762702 | Pharmaceutical preparation containing ibuprofen and a process for its preparation A pharmaceutical preparation containing ibuprofen is disclosed. In the preparation, the ibuprofen particles are enveloped by a coating of a hydro-colloid and fumaric acid. Preferably, the hydro-colloid comprises xanthan gum and/or maltodextrin. This prepa... | 08/09/1988 |
| 4758437 | Composition for long acting nicardipine preparation and process of producing the composition A spherical pellet like composition of nicardipine composed of small granular nuclei such as sugar particles coated with amorphous nicardipine or a salt thereof, a pH-dependent additive and a surface active agent. The spherical pellet like composition of ... | 07/19/1988 |
| 4741872 | Preparation of biodegradable microspheres useful as carriers for macromolecules A method for preparing biodegradable microspheres having a three-dimensional network in which biologically active macromolecular agents are physically entrapped therein. The microsphere is able to degrade and release the macromolecular agent at a controll... | 05/03/1988 |
| 4734286 | Crosslinked poly ଲ-alanine and compositions containing the same A water insoluble crosslinked poly ଲ-alanine is prepared by crosslinking poly ଲ-alanine with a crosslinking agent selected from the group consisting of formaldehyde and a dialdehyde or by irradiation of said poly ଲ-alanine with Co60... | 03/29/1988 |
| 4722815 | Process of making a synthetic resin product containing a molecular inclusion compound in cyclodextrin A synthetic resin product contains various substances such as perfumes, insectifuges/insecticides, mold/mildew-proofing agents and anti-fungi agents which are inactivated by forming an inclusion compound thereof in cyclodextrin and coating them with glyci... | 02/02/1988 |
| 4720384 | Manufacture of hollow fine tubular drug delivery systems Pharmaceutical compositions are provided which contain hollow fine tube drug delivery systems. The compositions comprise a pharmaceutically suitable carrier, preferably in the form of a capsule, tablet, suspension, or suppository, and at least one drug de... | 01/19/1988 |
| 4711777 | Pharmaceutical tablets Novel tablets comprising (a) 80 to 98% by weight of a mixture of trimethoprim and/or an acid addition salt thereof and a sulfonamide and/or a salt thereof in a weight ratio of 1:20 to 20:1 and (b) a pharmaceutically acceptable synthetic ion exchange resin... | 12/08/1987 |
| 4690825 | Method for delivering an active ingredient by controlled time release utilizing a novel delivery vehicle which can be prepared by a process utilizing the active ingredient as a porogen Delivery vehicles comprised of a polymeric bead having a network of pores with an active ingredient held within the network are provided for use in a method to provide controlled release of the active ingredient. The network of pores is substantially non-... | 09/01/1987 |
| 4595587 | Divisible pharmaceutical tablet with delayed active ingredient release A novel divisible delayed release pharmaceutical tablet, wherein the rate of release of active ingredient is independent of the size and nature of the total surface area, and the fragments of which have the same characteristics of release of active ingred... | 06/17/1986 |
| 4490436 | Polymer filler particles with filler free coating A polymer particle produced by forming a layer of filler-free polymer (II) on the surface layer of a filler-containing polymer particle (I) by polymerization of a monomer composed mainly of an ethylenically unsaturated compound in the presence of the poly... | 12/25/1984 |
| 4473545 | Composite materials An animal feed additive comprises a composite of a relatively insoluble binder, a particulate soluble material and an active material. The particulate material is such that it is readily soluble under a particular range of pH conditions, e.g. under said c... | 09/25/1984 |
| 4438239 | Microsphere coated substrate containing reactive aldehyde groups A synthetic organic resin is coated with a continuous layer of contiguous, tangential, individual microspheres having a uniform diameter preferably between 100 Angstroms and 2000 Angstroms. The microspheres are an addition polymerized polymer of an unsatu... | 03/20/1984 |
| 4432968 | Weight control with fat imbibing polymers Pharmacologically-acceptable fat imbibing polymers are introduced into the gastrointestinal tract of animals to control body weight.... | 02/21/1984 |
| 4404183 | Sustained release pharmaceutical composition of solid medical material Sustained release pharmaceutical compositions of a solid medical material which contains an amorphous solid medical material, polyethylene oxide, and at least one basic substance selected from the group consisting of hydroxypropylmethyl cellulose, hydroxy... | 09/13/1983 |
| 4393076 | Anti-inflammatory and analgesic gel composition An anti-inflammatory analgesic gel composition comprising (1) ketoprofen and/or flurbiprofen as the effective ingredient, as well as (2) a glycol, lower alcohol, water and/or a mixture of a lower alcohol with water, (3) a gel-forming agent and, if desired... | 07/12/1983 |
| 4344934 | Therapeutic compositions with enhanced bioavailability Novel compositions comprising wetted mixtures of poorly soluble drugs with water soluble polymers useful in increasing bioavailability are disclosed.... | 08/17/1982 |
| 4342745 | Use of polyvinyl alcohols for the treatment of lesions The subject of the present invention is the use of a polyvinyl alcohol, that is insoluble in cold water, in the form of a powder or granulate for the treatment of lesions and especially a method of treating lesions.... | 08/03/1982 |
| 4329332 | Biodegradable submicroscopic particles containing a biologically active substance and compositions containing them Biodegradable particles, with a diameter smaller than 500 nanometers, formed by the micellar polymerization of an alkyl-cyano-acrylate where the term "alkyl" means a lower alkyl radical having 1 to 4 carbon atoms and containing a biologically active subst... | 05/11/1982 |
| 4254100 | Vitamin A compositions Microcrystalline vitamin A acetate dry free-flowing powders containing microcrystalline vitamin A acetate and a process for their preparation are disclosed.... | 03/03/1981 |
| 4230809 | Pressure-resistant polyurethane-polyurea particles for the encapsulation of active ingredients and process for their manufacture Pressure-resistant polyurethane-polyurea particles with textured internal mass prepared from a liquid phase immiscible with water and containing organic solvents, isocyanate prepolymers and optionally active substances or mixtures of active substances, th... | 10/28/1980 |
| 4228152 | Polymers containing prostaglandin radicals, process for their preparation and use thereof There are disclosed non-toxic polymers having a molecular weight between 1,000 and 1,500,000 and containing prostaglandin radicals directly connected or connected through an oxyalkylenic, aminoalkylenic, or oxyaminoalkylenic chain to a polyacrylic or poly... | 10/14/1980 |
| 4172120 | Cholestyramine compositions and method for treating biliary gastritis A solid pharmaceutical composition comprising anhydrous cholestyramine, 0.6 to 1.7 parts by weight of low viscosity grade alginic acid/sodium alginate per weight of cholestyramine, the low viscosity grade alginic acid/sodium alginate having 0 to 75% of th... | 10/23/1979 |
| 4113853 | Haptoglobin insolubilized by being fixed in fibrin Because of its large hemoglobin-binding capacity, high physical strength, and ability to be reused on regeneration, the active haptoglobin fixed and insolubilized by embedding into or by chemical interlinking with fibrin is useful for absorbing and removi... | 09/12/1978 |
| 4112215 | Copolymeric resin binder powders Powders of physiologically-tolerable copolymers of vinyl and vinylidene monomers, said copolymers being useful as fast-dissolving resin binders for the preparation of pharmaceutical coatings, having a residual monomer content of less than 0.05 percent by ... | 09/05/1978 |
| 4105779 | Anthelmintic process for domestic animals This invention relates to a novel anthelmintic composition comprising a complex chemical compound of calcium salt of O-methyl-O-(2,2-dichlorovinyl)phosphoric acid with O, O-dimethyl-O-(2,2-dichlorovinyl)phosphate, and a specifically selected thermopl... | 08/08/1978 |
| 3996347 | Plant virus treatment It has been found that plant viruses and viroids can be inhibited by treating plants infected with or exposed to viruses or viroids with a virus-inhibiting amount of a maleic acid, maleic anhydride or fumaric acid copolymer.... | 12/07/1976 |
| 3966902 | Polymer complex carriers for an active ingredient Compositions comprising an effective amount of an active ingredient such as a medicinal agent, disinfectant, pesticide, insect repellant, or a cosmetic agent such as an antiperspirant, a bath oil, a fragrance, sunscreen, soap, hair dye, tanning agent, etc... | 06/29/1976 |
| 3962419 | Stabilized antibiotic SF-837 preparation This invention relates to an antibiotic preparation comprising a macrolide antibiotic, which is highly stabilized against an acidic solution or acidic substance because of the presence of a polymer component incorporated with the macrolide antibiotic by s... | 06/08/1976 |