Did You Know...
...that the video game, Pong, was invented by a guy who graduated at the bottom of his engineering class? Nolan Bushnell spent more time running the games at a local amusement park than he did on his studies at the University of Utah. His dreams of working for Disney's amusement empire were dashed when the company wouldn't hire him. Taking a boring job, Nolan daydreamed about electronic versions of popular games. He invented Pong, the first video game, and went on to found Atari Co.
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| Number | Title | Issue Date |
| 8071134 | Thyroid hormone analogs and methods of use Disclosed are methods of treating subjects having conditions related to angiogenesis including administering an effective amount of a polymeric form of thyroid hormone, or an antagonist thereof, to promote or inhibit angiogenesis in the subject. Compositions of the ... | 12/06/2011 |
| 8062673 | Process for embolization using swellable and deformable microspheres A method for embolization treatment was developed in which microspheres with novel properties are administered in a mammal. The microspheres are made using a novel process that results in microspheres with new combined properties of high density, low fracture, high ... | 11/22/2011 |
| 8057824 | Compositions for achieving a therapeutic effect in an anatomical structure and methods of using the same Compositions and methods of using the compositions to achieve a therapeutic effect are provided. ... | 11/15/2011 |
| 8053000 | Compositions for drug delivery Substantially non-porous polymeric microparticles comprising a hydrophobic polymer and a plasticizer, and containing therein a bioactive or bioinactive agent. ... | 11/08/2011 |
| 8007831 | Loading of hydrophobic drugs into hydrophilic polymer delivery systems A process is described for loading hydrophilic polymer particles with a water-insoluble solvent-soluble drug. The particles are preferably embolic agents. The method provides particles having little or no drug at the surface and in a surface layer, whereby the burst... | 08/30/2011 |
| 8003129 | Enhanced transport using membrane disruptive agents Compositions and methods for transport or release of therapeutic and diagnostic agents or metabolites or other analytes from cells, compartments within cells, or through cell layers or barriers are described. The compositions include a membrane barrier transport enh... | 08/23/2011 |
| 7964219 | Pharmaceutical compositions for controlled release delivery of biologically active compounds The present invention provides compositions and methods for the controlled release delivery of one or more biologically active compounds to a subject. Specifically, the invention provides for a pharmaceutical composition for the controlled release delivery of biolog... | 06/21/2011 |
| 7910135 | Hydrogel wound dressing and biomaterials formed in situ and their uses The present invention relates to a method of forming shape-retentive and shape-conforming aggregate wound dressings and biomaterials composed of gel nanoparticles and wound or bodily fluid in which the aggregates are held together by non-covalent bond physical force... | 03/22/2011 |
| 7906148 | Latex medical articles for release of antimicrobial agents According to an aspect of the present invention, a medical article is provided which comprises a latex antimicrobial region. The latex antimicrobial region can constitute the entirety of the medical article, or it can constitute only a portion of the medical article... | 03/15/2011 |
| 7887846 | Process for preparation of swellable and degradable microspheres A process for producing microspheres was developed that provides microspheres that are swellable and degradable. The process is reliable and high yielding, and makes use of a low temperature azo initiator, a small molecule chlorinated solvent as the organic phase, a... | 02/15/2011 |
| 7862835 | Method of manufacturing a medical device having a porous coating thereon Methods of manufacturing drug-coated medical devices having a porous coatings thereon. The pores are created by solid particle additives added to a mixture comprising a solvent, a drug, and a polymer to create a suspension, which is applied to the medical device. Th... | 01/04/2011 |
| 7842312 | Polymeric compositions comprising therapeutic agents in crystalline phases, and methods of forming the same The present invention relates to a drug-containing polymeric composition comprising at least one therapeutic agent encapsulated in at least one biocompatible polymer, wherein at least a portion of the therapeutic agent in this polymeric composition is crystalline. T... | 11/30/2010 |
| RE41884 | Reduction of intravenously administered nanoparticulate-formulation-induced adverse physiological reactions Disclosed are methods of intravenous administration of nanoparticulate drug formulations to a mammal to avoid adverse hemodynamic effects: by reducing the rate and concentration of the nanoparticles in the formulations; or by pre-treating the subject with histamine;... | 10/26/2010 |
| 7794755 | Process for preparation of swellable and deformable microspheres A process for producing microspheres was developed that provides microspheres with new combined properties of high density, low fracture, high swell capacity, rapid swell, and deformability following swell. The process is reliable and high yielding, and makes use of... | 09/14/2010 |
| 7790201 | Granular sustained release preparation and production thereof There is disclosed a novel sustained release granular resin-pharmaceutical composition comprising an ion exchange resin complexed with a pharmaceutical material wherein said complex is embedded into and on the surface of a diffusion barrier material. There is also d... | 09/07/2010 |
| 7785632 | Thyroid hormone analogs and methods of use Disclosed are methods of treating subjects having conditions related to angiogenesis including administering an effective amount of a polymeric form of thyroid hormone, or an antagonist thereof, to promote or inhibit angiogenesis in the subject. Compositions of the ... | 08/31/2010 |
| 7727558 | Polymeric delivery agents and delivery agent compounds Polymeric delivery agents, delivery agent compounds and compositions comprising them which are useful in the delivery of active agents are provided. Methods of administration and preparation are provided as well. ... | 06/01/2010 |
| 7588780 | Embolization Embolic polymer particles are described. For example, the particles include pores such that the predominant size of pores near the center of the particles is greater than the predominant size of pores adjacent to periphery of the particle ... | 09/15/2009 |
| 7585521 | Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use Controlled release ceramic particles, processes for their preparation, controlled release ceramic particles prepared by such processes, compositions comprising such controlled release ceramic particles and methods of using controlled release ceramic particles are de... | 09/08/2009 |
| 7442385 | Chemoembolisation A composition for chemoembolotherapy of solid tumours comprises particles of a water-insoluble water-swellable synthetic anionic polymer and, absorbed therein an anthracycline. Suitably the polymer is a poly(vinyl alcohol) based polymer and the drug is doxorubicin. | 10/28/2008 |
| 7419685 | Process for producing solid dosage forms Solid dosage forms containing at least one polymer binder, at least one active ingredient and, where appropriate, conventional additives, wherein a physiologically tolerated, water-swellable graft copolymer or a mixture of graft copolymers is employed as polymeric b... | 09/02/2008 |
| 7413752 | Composite hydrogel drug delivery systems Compositions and methods are provided to control the release of relatively low molecular weight therapeutic species through hydrogels by first dispersing or dissolving such therapeutic species within relatively hydrophobic rate modifying agents to form a mixture. Th... | 08/19/2008 |
| 7387994 | Compositions and methods for producing vascular occlusion using a solid-phase platelet binding agent The present invention relates generally to methods and compositions for targeting and delivering solid-phase platelet-dependent vascular occlusion agents. In particular, particles or coils or stents coated with platelet binding agents are directed to target vasculat... | 06/17/2008 |
| 7374778 | Enhanced transport using membrane disruptive agents Compositions and methods for transport or release of therapeutic and diagnostic agents or metabolites or other analytes from cells, compartments within cells, or through cell layers or barriers are described. The compositions include a membrane barrier transport enh... | 05/20/2008 |
| 7371781 | Tumor environment-induced ligand-expressing nanocarrier system Drug delivery compositions for specific delivery of a drug to a tumor are described. These compositions include a core for sequestering the drug and a shell to which a ligand is attached for delivery of a drug to target cells. Since normal cells may also be targeted... | 05/13/2008 |
| 7371738 | Method of transdermal drug delivery using hyaluronic acid nanoparticles The present invention relates to the development of a hyaluronic acid and hyaluronic acid hybrid nanoparticle systems for the administration of active molecules, peptides, DNA and/or other hydrophilic or hydrophobic molecules, the composition of hyaluronic acid and ... | 05/13/2008 |
| 7364748 | Controlled morphologies in polymer drug for release of drugs from polymer films The present invention includes a drug release system. The drug release system comprises a bulk polymer phase and a polymeric drug-enriched phase within the bulk polymer phase. At least one drug is incorporated into the drug-enriched phase. ... | 04/29/2008 |
| 7357339 | Wet pulverizing of polysaccharides Polysaccharide is wet pulverized by ejecting a liquid dispersion of polysaccharide from a pair of nozzles under a high pressure of 70 to 250 MPa to form a pair of jets so that the jets collide against each other. The nozzles are oriented to define a collision angle ... | 04/15/2008 |
| 7357948 | Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use Controlled release ceramic particles, processes for their preparation, controlled release ceramic particles prepared by such processes, compositions comprising such controlled release ceramic particles and methods of using controlled release ceramic particles are de... | 04/15/2008 |
| 7354603 | Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use Controlled release ceramic particles, processes for their preparation, controlled release ceramic particles prepared by such processes, compositions comprising such controlled release ceramic particles and methods of using controlled release ceramic particles are de... | 04/08/2008 |
| 7354602 | Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use Controlled release ceramic particles, processes for their preparation, controlled release ceramic particles prepared by such processes, compositions comprising such controlled release ceramic particles and methods of using controlled release ceramic particles are de... | 04/08/2008 |
| 7351798 | Stabilized protein crystals, formulations comprising them and methods of making them This invention relates to methods for the stabilization, storage and delivery of biologically active macromolecules, such as proteins, peptides and nucleic acids. In particular, this invention relates to protein or nucleic acid crystals, formulations and composition... | 04/01/2008 |
| 7351430 | Shape-retentive hydrogel particle aggregates and their uses The present invention is related to hydrogel particles and aggregates formed therefrom having characteristics including, without limitation, shape-retentiveness, elasticity, controllable pore sizes and controllable degradation rates that render them useful for a wid... | 04/01/2008 |
| 7348031 | Method for preparing colloidal particles in the form of nanocapsules The invention relates to a process for the preparation of dispersible colloidal systems in the form of nanocapsules whose wall consists of a polymer obtained by the polycondensation of two monomers, α and β, and whose core consists of a substance B, characterized ... | 03/25/2008 |
| 7344705 | Composition comprising low density microspheres Low density microspheres, methods for preparing same, and use of same as contrast agents are described. The microspheres have a void which contains a gas or the vapor of a volatile liquid selected from the group consisting of aliphatic hydrocarbons, chlorofluorocarb... | 03/18/2008 |
| 7338657 | Injectable microspheres for tissue construction The present invention relates to injectable compositions comprising biocompatible, hydrophilic, non-toxic and substantially spherical microspheres associated with stem cells useful for tissue construction and generation. The invention also relates to methods of tiss... | 03/04/2008 |
| 7335391 | Method for coating implantable devices A method of forming a coating for an implantable medical device, such as a stent, is provided which includes applying a composition to the device in an environment having a selected pressure. ... | 02/26/2008 |
| 7335379 | Transdermal pharmaceutical formulation for minimizing skin residues This invention relates to novel transdermal or transmucosal pharmaceutical formulation which reduces the occurrences of contamination of other individuals and the transference to clothing of the user. The novel formulation includes at least one pharmacologically act... | 02/26/2008 |
| 7329413 | Coatings for drug delivery devices having gradient of hydration and methods for fabricating thereof Coatings for implantable medical devices, and methods for fabricating thereof, are provided. The coatings include a first polymer layer and a second polymer layer, where the second polymer has a higher degree of hydration than the first polymer. ... | 02/12/2008 |
| 7329402 | Methods of imaging and treatment Novel ultrasound methods comprising administering to a patient a targeted vesicle composition which comprises vesicles comprising a lipid, protein or polymer, encapsulating a gas, in combination with a targeting ligand, and scanning the patient using ultrasound. The... | 02/12/2008 |
