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| Number | Title | Issue Date |
| 7282221 | Antiviral product, use and formulation thereof An antiviral product is comprised of at least three dosages forms, each of which has a different release profile, with the Cmax for the antiviral product being reached in less than about twelve hours. In one embodiment, there is an immediate release dosag... | 10/16/2007 |
| 7241813 | End-capped polymers and compositions containing such compounds End-capped polymers, methods for making those end-capped polymers and compositions containing those end-capped polymers are disclosed. One of the disclosed end-capped copolymers has the formula: and may be combin... | 07/10/2007 |
| 7208480 | Polysaccharide based gel A fluid gel obtainable by a process which comprises subjecting a solution comprising a mixture of xanthan and one or more non-gelling polysaccharides selected from galactomannans or glucomannans in a solvent to shear while cooling the solution from a temperature abo... | 04/24/2007 |
| 7205337 | End-capped polymers and compositions containing such compounds End-capped polymers, methods for making those end-capped polymers, compositions containing those end-capped polymers, and methods for using those compositions are disclosed. One of the disclosed end-capped copolymers has the formula (I): | 04/17/2007 |
| 7182957 | Polymer blends that swell in an acidic environment and deswell in a basic environment A polymer blend is prepared by dissolving chitosan and a second polymer in an acidic aqueous solution to form an aqueous polymer blend, dehydrating said aqueous polymer blend, and recovering said polymer blend. The second polymer may be selected from the group consi... | 02/27/2007 |
| 7172766 | Controlled release insufflation carrier for medicaments Controlled release powder insufflation formulations are disclosed. The powder formulation includes cohesive composites of particles containing a medicament and a controlled release carrier which preferably includes one or more polysaccharide gums of natural origin. | 02/06/2007 |
| 7122204 | Antibiotic composition with inhibitor Antibiotic composition having four dosage forms with different release profiles providing for initial release of a beta lactam antibiotic followed by release of a beta-lactamase inhibitor, followed by release of the antibiotic followed by release of the inhibitor. I... | 10/17/2006 |
| 7115586 | Non-inclusion cyclodextrin complexes The invention provides a number of methods for enhancing the aqueous solubility of an active ingredient which is insoluble or sparingly soluble in water. In one preferred embodiment, solubilization of the active ingredient is enhanced by combining it with β-cyclode... | 10/03/2006 |
| 7114569 | Methods, cement compositions and suspending agents therefor The present invention includes methods of cementing, cement compositions and a suspending agent comprising boron treated low molecular weight dry ground guar splits. A cement composition of the invention comprises hydraulic cement, water and a boron treated low mole... | 10/03/2006 |
| 7105176 | Production of solid preparations of water-soluble, sparingly water-soluble or water-insoluble active compounds A process is described for producing solid preparations of at least one water-soluble, sparingly water-soluble or water-insoluble active compound suitable for the food and animal feed sectors or for pharmaceutical and cosmetic applications. In addition, the inventio... | 09/12/2006 |
| 7101573 | Simethicone solid oral dosage form The present invention provides a composition for forming a compressed solid dosage form that is a free-flowing compressible admixture of simethicone, an adsorbant, and an optional active agent, wherein the weight ratio of simethicone to adsorbent is at least 1:2.22.... | 09/05/2006 |
| 7084132 | Artemisinins with improved stability and bioavailability for therapeutic drug development and application A stable form of artemisinin wherein an artelinic acid or artesunic acid is complexed with cyclodextrin analogs, preferably, β-cyclodextrin. The complexed cyclodextrin artemisinin formulation shields the peroxide portion of the artemisinin backbone from hydrolytic ... | 08/01/2006 |
| 7081450 | Water soluble nanoparticles of hydrophilic and hydrophobic active materials and an apparatus and method for their production This invention provides a soluble nano-sized particles formed of a core (water-insoluble lipophilic compound or hydrophilic compound) and an amphiphilic polymer and which demonstrated improved solubility and/or stability. The lipophilic compound within the soluble n... | 07/25/2006 |
| 7025991 | Drug targeting system, method of its preparation and its use A composition and method of fabrication are presented with which nanoparticles may be used as a tool to deliver drugs to a specific target within or on a mammalian body. Specifically, by using stabilizers other than Dextran 70.000 during the polymerization process, ... | 04/11/2006 |
| 7022313 | Hydrogel particle formulation New compositions formed from the combination of an active substance with a hydrogel carrier moiety are provided. The compositions are suitable for use in high-velocity transdermal particle injection techniques. Methods of providing the new compositions are also prov... | 04/04/2006 |
| 7008627 | Use of complexes for the preparation of compositions for the treatment of sensitive skin, preparation process and hypoallergenic compositions This invention relates to new dermocosmetic and pharmaceutical compositions which are useful for improving and treating hyperreactive skin conditions and more generally allergic-type reactions and/or intolerance phenomena, whether they are caused by external factors... | 03/07/2006 |
| 6994873 | Multiparticulate formulations of lithium salts for oral administration suitable for once-a-day administration This invention refers to: multiparticulate formulations of Lithium salts for oral administration constituted by either modified release granules or mixtures of modified and conventional release granules, suitable for once-a-day adm... | 02/07/2006 |
| 6982091 | Vaginal delivery of chemotherapeutic agents and inhibitors of membrane efflux systems for cancer therapy Devices, methods, and compositions for cancer therapy by administration of chemotherapeutic agents and/or inhibitors of membrane efflux systems to the vagina for topical and systemic tumor targets. ... | 01/03/2006 |
| 6953593 | Sustained-release microencapsulated delivery system Disclosed is a process for producing sustained-release powders that is fast, efficient, and economical. The process involves melting an animal or vegetable oil with a melting point above 110 degrees F. in specially designed mixer through either the work energy input... | 10/11/2005 |
| 6951846 | Artemisinins with improved stability and bioavailability for therapeutic drug development and application A stable form of artemisinin wherein an artelinic acid or artesunic acid is complexed with cyclodextrin analogs, preferably, β-cyclodextrin. The complexed cyclodextrin artemisinin formulation shields the peroxide portion of the artemisinin backbone from hydrolytic ... | 10/04/2005 |
| 6939530 | Preparation of further diagnostic agents Microspheres are prepared by a process comprising (i) spray-drying a solution or dispersion of a wall-forming material in order to obtain intermediate microspheres and (ii) reducing the water-solubility of at least the outside of the intermediate microspheres. Suita... | 09/06/2005 |
| 6936275 | Amino acid modulated extended release dosage form Disclosed herein is a oral extended release dosage form comprising a plurality of granules of an effective amount of a pharmaceutically active compound, at least one amino acid, and an intragranular polymer in which the granule is dispersed within a hydrophilic extr... | 08/30/2005 |
| 6936277 | Pharmaceutical excipient having improved compressibility A method of preparing an excipient composition includes forming an aqueous slurry containing a mixture of microcrystalline cellulose in the form of a wet cake and a surfactant, said surfactant being present in an amount from about 0.1% to about 0.5% by weight of the... | 08/30/2005 |
| 6884885 | Production of cyclodextrin complexes The process entails increasing the concentration of cyclodextrin to 15% (w/w) and above to form complexes through a precipitation process in order to increase the yield of complexes, increase the amount of guest complexed, and decrease the particle size of the compl... | 04/26/2005 |
| 6884756 | Water-dispersible pellets A water-dispersible particle for delivery of nitrogen to a plant is disclosed. The water-dispersible particle also delivers an active ingredient such as a plant hormone to a desirable plant or a pesticide or herbicide to an undesirable organism. Methods for making a... | 04/26/2005 |
| 6878693 | Hydrophilic complexes of lipophilic materials and an apparatus and method for their production This invention provides a soluble inclusion complex formed of a water-insoluble lipophilic compound and an amphiphilic polymer and which demonstrated improved solubility and stability. The lipophilic compound within the inclusion complex may consist of pharmaceutica... | 04/12/2005 |
| 6852709 | Biologically useful polyphosphates The present invention provides biodegradable polymers, polymer compositions, particles composed thereof and methods of using same for the controlled release of a biologically active substance to a specified tissue or cells. Preferred polymers include biodegradable, ... | 02/08/2005 |
| 6828334 | Fenofibrate-cyclodextrin inclusion complexes and their pharmaceutical composition The present invention relates to pharmaceutical compositions containing fenofibrate in the form of an inclusion complex with cyclodextrin, having high dissolution profile and in vivo enhanced bioavailability as compared with plain micronized fenofibrate compositions... | 12/07/2004 |
| 6793938 | Biodegradable compositions for the controlled release of encapsulated substances Pharmaceutical compositions that enable the release of a physiologically active substance over a prolonged period of time following administration to a patient are described. The pharmaceutical compositions are provided by encapsulation of a physiologically active s... | 09/21/2004 |
| 6793937 | Method of delivering active material within hydrogel microbeads A method of delivering active material using microbeads comprising droplets of active material entrained in a hydrophilic matrix. Compositions comprising the microbeads may be sprayable. The microbeads of the invention may be controllable by exposing the microbeads ... | 09/21/2004 |
| 6774151 | Method of producing an absorbent foam material A method of producing a porous, liquid absorbent, open-cell polymeric foam material having properties which makes it suitable for use as an absorbent structure in absorbent articles such as diapers, pant diapers, sanitary napkins, incontinence guards, wound dressing... | 08/10/2004 |
| 6761910 | Pharmaceutical composition for the treatment of acute disorders A pharmaceutical composition for the treatment of acute disorders is described. The composition comprises an essentially water-free, ordered mixture of at least one pharmaceutically active agent in the form of microparticles which are adhered to the surfaces of carr... | 07/13/2004 |
| 6759059 | Fentanyl composition for the treatment of acute pain A pharmaceutical composition for the treatment of acute pain by sublingual administration is described. The composition comprises an essentially water-free, ordered mixture of fentanyl or a pharmaceutically acceptable salt thereof in the form of microparticles which... | 07/06/2004 |
| 6730322 | Matrices formed of polymer and hydrophobic compounds for use in drug delivery A lipid or other hydrophobic or amphiphilic compound (collectively referred to herein as “hydrophobic compounds”) is integrated into a polymeric matrix for drug delivery to alter drug release kinetics. In embodiments where the drug is water soluble, the drug is ... | 05/04/2004 |
| 6726934 | Micro-particulate and nano-particulate polymeric delivery system The present invention provides a method of making particles useful in drug delivery, comprising the steps of: contacting polyanionic polymers with cations in a stirred reactor so that polyanions and the cations react to form particles. ... | 04/27/2004 |
| 6713088 | Low viscosity filler composition of boron nitride particles of spherical geometry and process A low viscosity filler boron nitride agglomerate particles having a generally spherical shape bound together by an organic binder and to a process for producing a BN powder composition of spherically shaped boron nitride agglomerated particles having a treated surfa... | 03/30/2004 |
| 6706263 | Composition for alleviating symptoms of uremia in patients Microencapsulated and/or enteric coated compositions containing a mixture of sorbents with specific adsorption affinities for uremic toxins including ammonia, urea, creatinine, phenols, indoles, and middle molecular weight molecules and a bacterial source which meta... | 03/16/2004 |
| 6689388 | Microencapsulated delivery system for high viscosity fluids Disclosed is a process for producing powders from high viscosity fluids including mixing a mixture comprising a high viscosity fluid and at least one absorbing agent until a dry dispersion is produced; combining, under shear, a combination of the dry disp... | 02/10/2004 |
| 6689345 | Care or make-up composition containing fibers and a hydrophilic polyoganosiloxane A care or make-up composition for keratin substances such as the skin, the lips or superficial body growths, this composition containing fibers and particles of an at least partially crosslinked solid elastomeric polyorganosiloxane suspended in an aqueous... | 02/10/2004 |
| 6689755 | Method of stabilizing biologically active substances The present invention relates to a rapid and readily reproducible process for stabilizing biologically active substances by combining the biologically active substance witha a stabilizingmixture and drying the resulting mixture into a dry, amorphous produ... | 02/10/2004 |
