Did You Know...
...that it was melting ice cream that inspired the invention of the outboard motor? It was a lovely August day and Ole Evinrude was rowing his boat to his favorite island picnic spot. As he rowed, he watched his ice cream melt and wished he had a faster way to get to the island. At that moment the idea for the outboard motor was born!
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| Number | Title | Issue Date |
| 8168228 | Antibiotic clarithromycin micropellet compositions An oral suspension comprising (a) an antibiotic composition which comprises coated micropellets and optionally one or more excipients, (b) additional excipients, and (c) a solvent, wherein said coated micropellets comprise (i) a core comprising at least one antibiot... | 05/01/2012 |
| 8153160 | Pharmaceutical dosage forms comprising an active ingredient combination of nifedipine and/or nisoldipine and an angiotensin II antagonist The present invention relates to a pharmaceutical dosage form comprising an active ingredient combination of nifedipine and/or nisoldipine and at least one angiotensin II antagonist, characterized in that the active ingredient combination undergoes controlled (modif... | 04/10/2012 |
| 8119166 | Methods of treatment using a gastric retained gabapentin dosage A method of treatment for epilepsy and other disease states is described, which comprises delivery of gabapentin in a gastric retained dosage form. ... | 02/21/2012 |
| 8088415 | Diffusion-controlled dosage form and method of fabrication including three dimensional printing The invention includes a core-and-shell dosage form or unit in which the core contains API and in which the shell substantially governs the release such as by controlling diffusion of API through the shell. The shell may comprise a release-blocking polymer, and part... | 01/03/2012 |
| 8003128 | Polylactide nanoparticles A drug targeting system for administering a pharmacologically active substance to the central nervous system of a mammal across the animal's blood brain barrier. The drug targeting system comprises nanoparticles made of poly(DL-lactide) and/or poly(DL-lactide-co-gly... | 08/23/2011 |
| 7985427 | Gastric juice-resistant device for releasing mucoadhesive active substance excipients, and method for producing this gastric juice-resistant device The invention relates to a gastric juice-resistant device for releasing active substance excipients having delayed intestinal passage from a gastric juice-resistant enclosure, and which serves to increase the active substance concentration in the intestines. The inv... | 07/26/2011 |
| 7927629 | Method and compositions for polymer nanocarriers containing therapeutic molecules A method of controlling a physical characteristic of polymeric nanocarrier-encapsulated protein particles includes altering or selecting a weight percentage of a hydrophobic polymer block in a total amphiphilic diblock copolymer of a primary emulsion of a double emu... | 04/19/2011 |
| 7758892 | Medical devices having multiple layers Described herein are medical devices which are configured for implantation or insertion into a subject, preferably a mammalian subject. The medical devices contain one or more multilayer regions, which contain: (a) one or more (typically a plurality of) charged nano... | 07/20/2010 |
| 7691413 | Composite particle and process for producing the same The invention provides a composite particle, a process for producing the same, and cosmetics containing the same The invention relates to composite particles containing a polyolefin-based resin having a crystallization degree of 80% or less and zinc oxide and obtain... | 04/06/2010 |
| 7510731 | Water-soluble stabilized self-assembled polyelectrolytes The present invention is directed toward water-soluble supramolecular self-assemblies and a process for their preparation via micellization of polyelectrolytes through the use of hydrophobic monomeric units. In this invention the polyelectrolyte segment ultimately f... | 03/31/2009 |
| 7465463 | Compositions comprising microspheres with anti-inflammatory properties for healing of ocular tissues The present invention relates to compositions of microspheres suitable for application to ocular injuries and inflammation, and to methods of use of the compositions alone or in combination with other agents in the prevention and treatment of ocular injuries and inf... | 12/16/2008 |
| 7442385 | Chemoembolisation A composition for chemoembolotherapy of solid tumours comprises particles of a water-insoluble water-swellable synthetic anionic polymer and, absorbed therein an anthracycline. Suitably the polymer is a poly(vinyl alcohol) based polymer and the drug is doxorubicin. | 10/28/2008 |
| 7438930 | Controlled release formulations having rapid onset and rapid decline of effective plasma drug concentrations The invention is directed to oral modified/controlled release drug formulations which provide a rapid initial onset of effect and a prolonged duration of effect. Preferably, the peak concentration is lower than that provided by the reference standard for immediate r... | 10/21/2008 |
| 7431944 | Delivery of multiple doses of medications Dosage forms for oral administration of a methylphenidate drug are provided. The dosage forms provide a substantially immediate dose of methylphenidate upon ingestion, followed by one or more additional doses at predetermined times. By providing such a drug release ... | 10/07/2008 |
| 7431943 | Controlled release and taste masking oral pharmaceutical compositions Controlled release and taste masking compositions containing one or more active principles inglobated in a three-component matrix structure, i.e. a structure formed by successive amphiphilic, lipophilic or inert matrices and finally inglobated or dispersed in hydrop... | 10/07/2008 |
| 7427415 | Implantation of encapsulated biological materials for treating diseases The present invention relates to compositions and methods of treating a disease, such as diabetes, by implanting encapsulated biological material into a patient in need of treatment. This invention provides for the placement of biocompatible coating materials around... | 09/23/2008 |
| 7425528 | Stabilization of granules The present invention relates to granules comprising a core matrix and one or more coatings, wherein the core matrix comprises: An active compound, a synthetic polymer, where the amount of polymer added is 0.1 to 10% by weight of the matrix and one or more antioxida... | 09/16/2008 |
| 7422758 | Sustained release vitamin composition A therapeutic formulation in the form of a beadlet, suitable for oral administration and adapted to provide immediate and sustained release of therapeutic material. Each beadlet comprises an extruded-spheronized inner core containing at least one medicament e.g. a s... | 09/09/2008 |
| 7423004 | Solid dispersion compositions Disclosed is a water-dispersible solid composition of a sparingly water-soluble compound in a particulatable lipidic carrier, methods for the preparation and use of the same. The compositions of this intention provide improved solubility and dissolution characterist... | 09/09/2008 |
| 7413750 | Process for producing solid oral dosage forms with sustained release of active ingredient The present invention relates to a process for producing solid oral dosage forms with sustained release of active ingredient, comprising at least one active ingredient, a preformulated mixture of polyvinyl acetate and polyvinylpyrrolidone, where appropriate, water-s... | 08/19/2008 |
| 7408018 | Elastomeric functional biodegradable copolyester amides and copolyester urethanes The invention provides elastomeric copolyester amides, elastomeric copolyester urethanes, and methods for making the same. The polymers are based on α-amino acids and possess physical, chemical and biodegradation properties that render them suitable for use in the ... | 08/05/2008 |
| 7390504 | HDL-boosting combination therapy complexes A pharmaceutical composition including therapeutically effective amounts of at least one HMG-CoA reductase inhibitor present as a dyhydroxyacid salt and at least one additional therapeutic agent. ... | 06/24/2008 |
| 7371457 | Nanoparticle comprising nanoshell of thickness less than the bulk electron mean free path of the shell material The present invention is for particulate compositions and methods for producing them that can absorb or scatter electromagnetic radiation. The particles are homogeneous in size and are comprised of a nonconducting inner layer that is surrounded by an electrically co... | 05/13/2008 |
| 7365059 | Photocrosslinked-polysaccharide composition and production process of the same A process for producing a photocrosslinked-polysaccharide composition, which comprises: freezing a photoreactive polysaccharide-containing solution comprising a photoreactive polysaccharide in which a photoreactive group is bound to a polysaccharide, an aqueous solv... | 04/29/2008 |
| 7348031 | Method for preparing colloidal particles in the form of nanocapsules The invention relates to a process for the preparation of dispersible colloidal systems in the form of nanocapsules whose wall consists of a polymer obtained by the polycondensation of two monomers, α and β, and whose core consists of a substance B, characterized ... | 03/25/2008 |
| 7348030 | Nanoparticles for targeting hepatoma cells The nanoparticles composed of γ-PGA-PLA block copolymers that are conjugated with galactosamine as a potential drug delivery system and loaded with anticancer drugs for treating liver cancers. ... | 03/25/2008 |
| 7338928 | System for releasing encapsulated active ingredients The present invention relates to a controlled release system that can be incorporated in cosmetic, personal care, and household products to effectively encapsulate wide range of active ingredients and sensory markers and release them in response to moisture or over ... | 03/04/2008 |
| 7338971 | Treatment of inflammatory, cancer, and thrombosis disorders This invention provides for the treatment of inflammatory, cancer and thrombotic disorders through the administration, in combination, of a COX2 inhibitor, low dose aspirin, and antioxidant flavanoids, flavonoids or isoflavones and at least one of these combinations... | 03/04/2008 |
| 7332218 | Electrically disbonding materials An electrochemically disbondable composition is provided having a matrix functionality and an electrolyte functionality. The matrix functionality provides an adhesive bond to a substrate, and the electrolyte functionality provides sufficient ionic conductivity to th... | 02/19/2008 |
| 7323540 | Process for preparing microrods using liquid-liquid dispersion The invention provides a method for forming polymer microrods, the method including the steps of providing a polymer solution comprising a polymer dissolved in a first solvent; providing a dispersion medium comprising a second solvent, wherein the first solvent and ... | 01/29/2008 |
| 7323175 | Immunogenicity of glucan binding protein Immunogenic compositions and subunit vaccines for dental caries are described which comprise peptide subunits of glucan binding protein-B and peptide subunits of glucan binding protein-B in combination with peptide subunits of glucosyltransferase. Methods of provoki... | 01/29/2008 |
| 7320724 | Compositions for the staged release of nutrients to plants A fertilizer composition is adapted to stage the controlled release of nutrients such that the composition need only be applied once in a plant's growth cycle, but with individual nutrients releasing at predetermined, staged intervals targeted to the precise needs o... | 01/22/2008 |
| 7316818 | Liposome drug delivery of polycyclic, aromatic, antioxidant or anti-inflammatory compounds This invention comprises pharmaceutical compositions for administering a polycyclic, aromatic, antioxidant or anti-inflammatory compound to an animal. Particularly provided are proliposomal compositions that are advantageously used to deliver polycyclic, aromatic, a... | 01/08/2008 |
| 7316821 | Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer A stabilized solid controlled release dosage form having a coating derived from an aqueous dispersion of ethylcellulose is obtained by overcoating a substrate including a therapeutically active with an aqueous dispersion of ethylcellulose and then curing the coated ... | 01/08/2008 |
| 7314638 | Preparing method for controlled released type tablet tamsulosin HCL and the tablet thereof The present invention relates to a simple and effective method for preparing a tamsulosin HCl sustained-release tablet and a tamsulosin HCl sustained-release tablet produced thereby. The method comprises the steps of: dissolving tamsulosin HCl as an active ingredien... | 01/01/2008 |
| 7314640 | Formulation and process for drug loaded cores The present invention relates to a controlled release pellet of metoprolol and its pharmaceutically acceptable salts that uses a water soluble or a water swellable inert starting seed or core. ... | 01/01/2008 |
| 7311980 | Polyactive/polylactic acid coatings for an implantable device A polymeric coating for a medical device that comprises poly(lactic acid) and a block copolymer including blocks of poly(ethylene glycol) and poly(butylene terephthalate) is provided. ... | 12/25/2007 |
| 7309500 | Microparticles A method of forming particles, comprises accelerating a first stream comprising a first liquid, applying a charging voltage of at most 1.5 kV to the first stream, and vibrating the first stream, to form particles. ... | 12/18/2007 |
| 7309685 | Textile finishing agents for imparting a sensory effect during use A method for treating fibers, yarns or textiles to improve the sensory effect for a user or weaver of a fabric article. The method treats the fiber, yarns or textiles with an emulsion containing 15-30% by weight of a mixture of waxes having melting points in the ran... | 12/18/2007 |
| 7303767 | Personal care compositions comprising coated/treated metal silicate absorbent particles Coated particles of metal (such as calcium) silicate that exhibit excellent odor neutralization and sebum absorption properties when present within certain cosmetic and/or personal care formulations and suspensions are provided. Uncoated calcium silicate exhibits a ... | 12/04/2007 |
