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| Number | Title | Issue Date |
| 8394415 | Modified release analgesic suspensions A pharmaceutical dosage form comprising non-steroidal-anti-inflammatory drugs, in particular propionic acid derivatives such as ibuprofen, along with a second active ingredient having a shorter therapeutically effective plasma concentration duration, such as phenyle... | 03/12/2013 |
| 8337901 | Process for the manufacture of cellulose sulfate with improved characteristics The invention refers to a method for the production of cellulose sulfate which is completely water-soluble and has an adjustable solution viscosity in aqueous solution, which qualifies the produced sodium cellulose sulfate (SCS) as auxiliary material with ideal biol... | 12/25/2012 |
| 8273375 | Multiparticle pharmaceutical dosage form for a low-soluble active substances and method for producing said pharmaceutical dosage form The invention relates to an oral multiparticle pharmaceutical dosage form in the form of a receptacle reducing the pH values of stomach, containing a plurality of pellets, particles, granules or agglomerates whose mean diameter ranges from 50 to 2500 μn substential... | 09/25/2012 |
| 7879362 | Oral pharmaceutical compositions with controlled release and prolonged absorption The invention concerns a galenic system with prolonged/controlled release of the medicinal and/or nutritional active principle, for oral administration. The aim is to provide a system enabling to obtain with one single tolerable and acceptable dose of active princip... | 02/01/2011 |
| RE42096 | Oral pulsed dose drug delivery system A multiple pulsed dose drug delivery system for pharmaceutically active amphetamine salts, comprising an immediate-release component and an enteric delayed-release component wherein (1) the enteric release coating has a defined minimum thickness and/or (2) there is ... | 02/01/2011 |
| 7422758 | Sustained release vitamin composition A therapeutic formulation in the form of a beadlet, suitable for oral administration and adapted to provide immediate and sustained release of therapeutic material. Each beadlet comprises an extruded-spheronized inner core containing at least one medicament e.g. a s... | 09/09/2008 |
| 7413753 | Calcium phosphate delivery vehicles for osteoinductive proteins A composition for delivery of osteogenic proteins is disclosed. The composition comprises an osteogenic protein, a calcium phosphate material as a carrier, and an effective amount of an effervescent agent. Methods of making the compositions and methods of using the ... | 08/19/2008 |
| 7413781 | Gels for encapsulation of biological materials This invention provides novel methods for the formation of biocompatible membranes around biological materials using photopolymerization of water soluble molecules. The membranes can be used as a covering to encapsulate biological materials or biomedical devices, as... | 08/19/2008 |
| 7413750 | Process for producing solid oral dosage forms with sustained release of active ingredient The present invention relates to a process for producing solid oral dosage forms with sustained release of active ingredient, comprising at least one active ingredient, a preformulated mixture of polyvinyl acetate and polyvinylpyrrolidone, where appropriate, water-s... | 08/19/2008 |
| 7350479 | System and method for controlling growth of aquatic plants utilizing bio-eroding means implanted in triploid grass carp An “implant and forget” device for interacting with biota after a pre-established time period. Preferably, the biota are fauna and more particularly fish. In select embodiments, the device comprises packaging enclosing apparatus for timing interaction via openin... | 04/01/2008 |
| 7338668 | Drug carrier pellet production process The invention provides a process for the production of drug carrier pellets comprising spray-drying a solution of a physiologically tolerable cellulosic binder containing a physiologically tolerable inert particulate carrier having a particle size D (v, 0.5) of less... | 03/04/2008 |
| 7338928 | System for releasing encapsulated active ingredients The present invention relates to a controlled release system that can be incorporated in cosmetic, personal care, and household products to effectively encapsulate wide range of active ingredients and sensory markers and release them in response to moisture or over ... | 03/04/2008 |
| 7332586 | Nanoparticle delivery vehicle A nanoparticle delivery vehicle, comprising a nanoparticle, an active agent and a nuclear localization signal and methods of modulating gene expression and protein expression employing the nanoparticle delivery vehicle. A representative method includes providing a n... | 02/19/2008 |
| 7316821 | Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer A stabilized solid controlled release dosage form having a coating derived from an aqueous dispersion of ethylcellulose is obtained by overcoating a substrate including a therapeutically active with an aqueous dispersion of ethylcellulose and then curing the coated ... | 01/08/2008 |
| 7314640 | Formulation and process for drug loaded cores The present invention relates to a controlled release pellet of metoprolol and its pharmaceutically acceptable salts that uses a water soluble or a water swellable inert starting seed or core. ... | 01/01/2008 |
| 7309500 | Microparticles A method of forming particles, comprises accelerating a first stream comprising a first liquid, applying a charging voltage of at most 1.5 kV to the first stream, and vibrating the first stream, to form particles. ... | 12/18/2007 |
| 7303767 | Personal care compositions comprising coated/treated metal silicate absorbent particles Coated particles of metal (such as calcium) silicate that exhibit excellent odor neutralization and sebum absorption properties when present within certain cosmetic and/or personal care formulations and suspensions are provided. Uncoated calcium silicate exhibits a ... | 12/04/2007 |
| 7303768 | Preparation of aqueous clear solution dosage forms with bile acids Compositions for pharmaceutical and other uses comprising clear aqueous solutions of bile acids which do not form any detectable precipitates over selected ranges of pH values of the aqueous solution and methods of making such solutions. The compositions of the inve... | 12/04/2007 |
| 7303766 | Coated/treated metal silicate absorbent particles Coated particles of metal (such as calcium) silicate that exhibit excellent odor neutralization and sebum absorption properties when present within certain cosmetic and/or personal care formulations and suspensions are provided. Uncoated calcium silicate exhibits a ... | 12/04/2007 |
| 7297786 | RNA interference in respiratory epitheial cells The present invention is directed to small interfering RNA molecules targeted against a gene of interest in respiratory epithelial cells, and methods of using these RNA molecules. ... | 11/20/2007 |
| 7282221 | Antiviral product, use and formulation thereof An antiviral product is comprised of at least three dosages forms, each of which has a different release profile, with the Cmax for the antiviral product being reached in less than about twelve hours. In one embodiment, there is an immediate release dosag... | 10/16/2007 |
| 7282217 | Rapidly disintegrable tablets The invention provides a rapidly disintegrating tablet comprising an active ingredient, a water soluble, directly compressible carbohydrate, and a water soluble, directly compressible filler. Also provided is a method of producing a rapidly disintegrating tablet, wh... | 10/16/2007 |
| 7276253 | Stable drug form for oral administration with benzimidazole derivatives as active ingredient and process for the preparation thereof The invention relates to a stable medicament for oral administration which comprises (a) a core which contains an active ingredient selected from Omeprazole, Lansoprazole and Pantoprazole, together with customary pharmaceutical adjuvants, (... | 10/02/2007 |
| 7270831 | Orally administrable opioid formulations having extended duration of effect Sustained release oral solid dosage forms of opioid analgesics are provided as multiparticulate systems which are bioavailable and which provide effective blood levels of the opioid analgesic for at least about 24 hours. A unit dose of the opioid analgesic contains ... | 09/18/2007 |
| 7255878 | Stable benzimidazole formulation A stable composition with a benzimidazole derivative, such as Omeprazole, which does not contain a separating layer between the active compound and an enteric coating layer. Instead, the enteric coating layer is applied as a solution with a pH value of at least 6.5,... | 08/14/2007 |
| 7252842 | Induced phase transition method for the production of microparticles containing hydrophilic active agents Microparticles and a method for their production is described. The process of the present invention provides a simple, quick, and efficient one-pot process for the production of microparticles containing a hydrophilic active agent of various and uniform morphologies... | 08/07/2007 |
| 7235260 | Pharmaceutical compositions of a sparingly soluble glycogen phosphorylase inhibitor Pharmaceutical compositions of a particularly effective sparingly soluble glycogen phosphorylase inhibitor are disclosed, as well as methods of making such compositions and dosage forms from such compositions. ... | 06/26/2007 |
| 7235261 | Controlled release encapsulation This invention relates to a controlled release encapsulated dry powder that is formed by an emulsion comprising: A) a fully hydrolyzed polymer, B) a hydrophobic silica, C) a modified corn starch, and D) at least one fragrance oil, which is emulsified in water and sp... | 06/26/2007 |
| 7229624 | Ordered molecular presentation of antigens, method of preparation and use The invention provides compositions and processes for the production of ordered and repetitive antigen or antigenic determinant arrays. The compositions of the invention are useful for the production of vaccines for the prevention of infectious diseases, the treatme... | 06/12/2007 |
| 7223421 | Teste masked pharmaceutical particles Taste masked particles and chewable tablets made therefrom are disclosed. The taste masked particles comprise a core containing an active ingredient and a polymeric coating covering said core, said coating comprising a mixture of a) an enteric polymer; and b) an ins... | 05/29/2007 |
| 7220433 | Compositions for parenteral administration and sustained-release of therapeutic agents The present invention is directed to parenterally-administrable microparticles for providing sustained-release of a therapeutic agent in the body, where the microparticles include a polymeric core containing a therapeutically effective amount of a therapeutic agent ... | 05/22/2007 |
| 7214823 | Hydroxycitric acid complex metal salts, composition, and methods Described are tri-, tetra-, and penta-metal complex salts of hydroxycitric acid, compositions containing the same, and methods of making the same, where the salt comprises at least three different metals selected from zinc, magnesium, sodium, potassium, and calcium.... | 05/08/2007 |
| 7195769 | Pharmaceutical compositions of anti-tubercular drugs and process for their preparation A pharmaceutical composition of anti-tubercular drugs for oral use comprising Rifampicin and/or Isoniazid wherein the bioavailability of Rifampicin and/or other drugs is enhanced. Preferably the bioavailability of Rifampicin is enhanced by preventing its degradation... | 03/27/2007 |
| 7192603 | Pest controlling The present invention features a sustained-release microcapsule for long-term pest controlling. In general, a microcapsule has a capsule core including active pest-control ingredients and diluents, and a capsule shell which physically separates the capsule core from... | 03/20/2007 |
| 7189416 | Method for stable and controlled delivery of (-)-hydroxycitric acid A method for making the potassium, sodium and other hygroscopic salts of (−)-hydroxycitric acid and mixtures thereof workable by initial treatment with a desiccating agent, such as fumed silicon dioxide. These may be further rendered non-hygroscopic and non-reacti... | 03/13/2007 |
| 7179488 | Process for co-spray drying liquid herbal extracts with dry silicified MCC A process for preparing dry extracts from a liquid extract and at least one additional substance by a spray-drying process, characterized in that said at least one additional substance is added to the spray-drying process in a dry form during the spray-drying proces... | 02/20/2007 |
| 7172767 | Opioid agonist / antagonist combinations The invention is directed in part to oral dosage forms comprising a combination of an orally analgesically effective amount of an opioid agonist and an orally active opioid antagonist, the opioid antagonist being included in a ratio to the opioid agonist to provide ... | 02/06/2007 |
| 7166305 | Polyvalent metal-substituted starch products Improved starch-metal derivatives are provided which have excellent dry flow characteristics and ready dispersability in hot or cold water. The preferred derivatives comprise granules of starch which have been expanded or preswelled and cross-linked, followed by rea... | 01/23/2007 |
| 7166299 | Preparation of aqueous clear solution dosage forms with bile acids Compositions for pharmaceutical and other uses comprising clear aqueous solutions of bile acids which do not form any detectable precipitates over selected ranges of pH values of the aqueous solution and methods of making such solutions. The compositions of the inve... | 01/23/2007 |
| 7157101 | Micronized eplerenone compositions The invention relates to oral pharmaceutical compositions useful as aldosterone receptor blockers comprising the active agent micronized eplerenone in an amount of about 10 mg to about 1000 mg and one or more carrier materials. ... | 01/02/2007 |
