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| Number | Title | Issue Date |
| 7767231 | Taste-masking pharmaceutical compositions The present invention relates to a pharmaceutical composition for oral administration suitable for the preparation of a ready-to-use suspension comprising coated particles comprising an active substance having an unpleasant and/or bitter taste, such as clarithromyci... | 08/03/2010 |
| 7700131 | Powders having contact biocidal properties Powders having contact biocidal properties comprise a polysaccharide carrying atomic/metallic silver. The preferred polysaccharide is chitin, although other polysaccharides including chitosan, carboxymethyl celluloses and carrageenans can be used. The chitin may be ... | 04/20/2010 |
| 7422758 | Sustained release vitamin composition A therapeutic formulation in the form of a beadlet, suitable for oral administration and adapted to provide immediate and sustained release of therapeutic material. Each beadlet comprises an extruded-spheronized inner core containing at least one medicament e.g. a s... | 09/09/2008 |
| 7413781 | Gels for encapsulation of biological materials This invention provides novel methods for the formation of biocompatible membranes around biological materials using photopolymerization of water soluble molecules. The membranes can be used as a covering to encapsulate biological materials or biomedical devices, as... | 08/19/2008 |
| 7399528 | Powder particles with smooth surface for use in inhalation therapy Carrier particles, for use in the preparation of powdery mixtures for administration by inhalation, and having a median diameter of greater than 90 microns and a surface rugosity expressed as the fractal dimension of less than or equal to 1.1, may be prepared by sub... | 07/15/2008 |
| 7378110 | High pressure spray-dry of bioactive materials This invention provides compositions and methods providing, e.g., stable powder particles containing bioactive materials. The methods include, e.g., high pressure spraying of the bioactive materials in solution or suspension, with viscosity enhancing agents and/or s... | 05/27/2008 |
| 7357943 | Pharmaceutical preparation in the form of a suspension comprising an acid-labile active ingredient The present invention relates to the field of pharmaceutical technology and describes a novel pharmaceutical preparation in the form of a suspension comprising an acid-labile active ingredient, in particular an acid-labile proton pump inhibitor. The invention also r... | 04/15/2008 |
| 7351432 | Compositions containing saccharide and hydrophobic silica A particulate composition comprises from 40 to 80% by weight of a water-soluble saccharide, from 1.5 to 10% by weight of a finely particulate amorphous hydrophobic silica having a surface area in the range of from 80 to 300 m2/g and water. The composition... | 04/01/2008 |
| 7344734 | Powder formulation The invention relates to a powder formulation for administration by inhalation comprising an active substance and a pharmaceutically acceptable excipient, which composition has the form of a physical mixture and comprises from 5 to 25 wt. % of the excipient, and whe... | 03/18/2008 |
| 7338668 | Drug carrier pellet production process The invention provides a process for the production of drug carrier pellets comprising spray-drying a solution of a physiologically tolerable cellulosic binder containing a physiologically tolerable inert particulate carrier having a particle size D (v, 0.5) of less... | 03/04/2008 |
| 7338931 | Hydrophobic biomolecular structure The present invention relates to a new hydrophobe biomolecular structure, which is compacted due to the passing of the structure over its point of collapse, a method for the preparation of the structure and use of the new structure for the manufacture of a medicamen... | 03/04/2008 |
| 7332586 | Nanoparticle delivery vehicle A nanoparticle delivery vehicle, comprising a nanoparticle, an active agent and a nuclear localization signal and methods of modulating gene expression and protein expression employing the nanoparticle delivery vehicle. A representative method includes providing a n... | 02/19/2008 |
| RE40059 | Sensitive substance encapsulation A process for stabilizing a sensitive substance; (a) plating a sensitive substance onto a solid carrier under a controlled atmosphere to reduce loss of the sensitive substance; (b) encapsulating the plated material under controlled atmosphere and airflow to reduce v... | 02/12/2008 |
| 7326422 | Dissolvable oxides for biological applications Controllably dissolvable silica-xerogels prepared via sol-gel process and their use. A delivery device including controllably dissolvable silica-xerogel into which structure a biologically active agent is incorporated. Pharmaceutical preparations including this devi... | 02/05/2008 |
| 7320724 | Compositions for the staged release of nutrients to plants A fertilizer composition is adapted to stage the controlled release of nutrients such that the composition need only be applied once in a plant's growth cycle, but with individual nutrients releasing at predetermined, staged intervals targeted to the precise needs o... | 01/22/2008 |
| 7316821 | Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer A stabilized solid controlled release dosage form having a coating derived from an aqueous dispersion of ethylcellulose is obtained by overcoating a substrate including a therapeutically active with an aqueous dispersion of ethylcellulose and then curing the coated ... | 01/08/2008 |
| 7314640 | Formulation and process for drug loaded cores The present invention relates to a controlled release pellet of metoprolol and its pharmaceutically acceptable salts that uses a water soluble or a water swellable inert starting seed or core. ... | 01/01/2008 |
| 7303766 | Coated/treated metal silicate absorbent particles Coated particles of metal (such as calcium) silicate that exhibit excellent odor neutralization and sebum absorption properties when present within certain cosmetic and/or personal care formulations and suspensions are provided. Uncoated calcium silicate exhibits a ... | 12/04/2007 |
| 7304432 | Plasma display panel with phosphor layer arranged in non-display area A Plasma Display Panel (PDP) in which a dummy area is arranged so as to retain phosphor paste ejected from extra nozzles when a plurality of nozzles are used to apply phosphor paste. The PDP includes a first substrate and a second substrate opposing each other; addr... | 12/04/2007 |
| 7303767 | Personal care compositions comprising coated/treated metal silicate absorbent particles Coated particles of metal (such as calcium) silicate that exhibit excellent odor neutralization and sebum absorption properties when present within certain cosmetic and/or personal care formulations and suspensions are provided. Uncoated calcium silicate exhibits a ... | 12/04/2007 |
| 7288319 | Forming a chemically cross-linked particle of a desired shape and diameter Chemically cross-linked polymeric particles are formed using mechanical rather than chemical processes, facilitating production of small-diameter particles in a manner largely independent of the viscosity or density of the polymer. For example, an uncross-linked res... | 10/30/2007 |
| 7279597 | Phenyl amine carboxylic acid compounds and compositions for delivering active agents Phenyl amine carboxylic acid compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. ... | 10/09/2007 |
| 7276534 | Carbon-substituted diketopiperazine delivery systems Compositions useful in the delivery of active agents are provided. These delivery compositions include (a) an active agent; and (b) a carrier of at least one mono-C-substituted or di-C-substituted diketopiperazine. Methods for preparing these compositions and admini... | 10/02/2007 |
| 7276364 | Nucleic acids encoding endotheliases, endotheliases and uses thereof Provided herein are endotheliases and portions, particularly, the protease domains, and nucleic acids that encode the endotheliases. The endotheliases are transmembrane proteases expressed in endothelial cells. The nucleic acids and encoded proteins and protease dom... | 10/02/2007 |
| 7270831 | Orally administrable opioid formulations having extended duration of effect Sustained release oral solid dosage forms of opioid analgesics are provided as multiparticulate systems which are bioavailable and which provide effective blood levels of the opioid analgesic for at least about 24 hours. A unit dose of the opioid analgesic contains ... | 09/18/2007 |
| 7258873 | Preservation of bioactive materials by spray drying This invention provides methods and compositions to preserve bioactive materials in a matrix of powder particles. Methods provide high-pressure gas spraying and/or near supercritical spraying of formulations followed by drying in a stream of conditioned gas to form ... | 08/21/2007 |
| 7259252 | Nanoparticles having oligonucleotides attached thereto and uses therefor The invention provides methods of detecting a nucleic acid. The methods comprise contacting the nucleic acid with one or more types of particles having oligonucleotides attached thereto. In one embodiment of the method, the oligonucleotides are attached to nanoparti... | 08/21/2007 |
| 7255878 | Stable benzimidazole formulation A stable composition with a benzimidazole derivative, such as Omeprazole, which does not contain a separating layer between the active compound and an enteric coating layer. Instead, the enteric coating layer is applied as a solution with a pH value of at least 6.5,... | 08/14/2007 |
| 7250403 | Biodegradable immunomodulatory formulations and methods for use thereof The invention provides new compositions and methods for immunomodulation of individuals. Immunomodulation is accomplished by administration of immunomodulatory polynucleotide/microcarrier (IMP/MC) complexes. The IMP/MC complexes may be covalently or non-covalently b... | 07/31/2007 |
| 7238355 | Coated material and process for producing the coated material A coated material and a process for producing the coated material which includes providing a coating agent comprising yeast cell wall fractions, as a primary constituent, consisting of cell residue of yeast which has been treated with enzymes, optionally subsequentl... | 07/03/2007 |
| 7235261 | Controlled release encapsulation This invention relates to a controlled release encapsulated dry powder that is formed by an emulsion comprising: A) a fully hydrolyzed polymer, B) a hydrophobic silica, C) a modified corn starch, and D) at least one fragrance oil, which is emulsified in water and sp... | 06/26/2007 |
| 7229949 | Safe delivery system for agriculturally active material A safe delivery system of agriculturally active material is formed using an encapsulation process. A microencapsulated suspension of agriculturally active material includes an encapsulating agent formed from a graft copolymer of starch and at least one vinyl monomer... | 06/12/2007 |
| 7226620 | Directly compressible tricalcium phosphate A compressible tricalcium phosphate agglomerate comprises tricalcium phosphate particles, each having an outer surface, and a binder comprising a polyvinylpyrollidone, carrageenan, or a guar gum, supported on at least a portion of the outer surface of at least a por... | 06/05/2007 |
| 7223748 | Pharmaceutical formulations for dry powder inhalers in the form of hard-pellets The invention provides a formulation to be administered as a dry powder for inhalation suitable for efficacious delivery of active ingredients into the low respiratory tract of patients suffering from a pulmonary disease such as asthma. In particular, the invention ... | 05/29/2007 |
| 7220414 | Degradable polyacetal polymers Degradable polyacetal polymers and functionalized degradable polyacetal polymers have properties favorable for use in pharmaceutical and biomedical applications. The degradable polyacetal polymers are relatively stable at physiological pH with favorable biodistribut... | 05/22/2007 |
| 7220433 | Compositions for parenteral administration and sustained-release of therapeutic agents The present invention is directed to parenterally-administrable microparticles for providing sustained-release of a therapeutic agent in the body, where the microparticles include a polymeric core containing a therapeutically effective amount of a therapeutic agent ... | 05/22/2007 |
| 7208483 | Polymeric delivery agents and delivery agent compounds Polymeric delivery agents, delivery agent compounds and compositions comprising them which are useful in the delivery of active agents are provided. Methods of administration and preparation are provided as well. ... | 04/24/2007 |
| 7198795 | methods for evaluating the effectiveness of dosage forms of microparticulate of nanoparticulate active agent compositions Disclosed are in vitro methods for evaluating the in vivo redispersibility of dosage forms of poorly water-soluble active agents. The methods utilize media representative of in vivo human physiological conditions. ... | 04/03/2007 |
| 7196059 | Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith Pharmaceutical compositions that include insulin, an insulin drug-oligomer conjugate, a fatty acid component, and a bile salt component or a bile salt component without a fatty acid component are described. The insulin drug is covalently coupled to an oligomeric moi... | 03/27/2007 |
| 7193084 | Polymorphic form of itraconazole The present invention provides a polymorphic form of itraconazole. ... | 03/20/2007 |
