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| Number | Title | Issue Date |
| 8133511 | Drug delivery system based on cationic siloxanyl macromonomers Matrix controlled diffusion drug delivery systems are described herein which are based on one or more silicon-containing monomers of the general formula: wherein L, X−, n, R1, R2, R3, R4, R5, R6, R7 and V are a... | 03/13/2012 |
| 8133510 | Form of administration based on crosslinked hydrophilic polymers The invention relates to a film-shaped form of administration for topically administering at least one agent and/or nutrient to a living being. Said form of administration comprises at least one agent-containing and/or nutrient-containing layer that is based on cros... | 03/13/2012 |
| 8133512 | Drug delivery systems based on catonic siloxanyl macromonomers Matrix controlled diffusion drug delivery systems based on one or more silicon-containing monomers of the general formula: wherein L, X−, n, R1, R2, R3, R4, R5, R6, R7 and V are as set forth herein. ... | 03/13/2012 |
| 8025902 | Low-irritation compositions and methods of making the same Provided are compositions comprising a low molecular weight, non-crosslinked, linear acrylic copolymer and at least one surfactant selected from the group consisting of anionic surfactants, amphoteric surfactants, and combinations of two or more thereof, and methods... | 09/27/2011 |
| 7943174 | Controlled release hydrocodone formulations A solid oral controlled-release oral dosage form of hydrocodone is disclosed. The dosage form comprising an analgesically effective amount of hydrocodone or a pharmaceutically acceptable salt thereof, and a sufficient amount of a controlled release material to rende... | 05/17/2011 |
| 7803403 | Low-irritation compositions and methods of making the same Provided are compositions comprising a low molecular weight, non-crosslinked, linear acrylic copolymer and at least one surfactant selected from the group consisting of anionic surfactants, amphoteric surfactants, and combinations of two or more thereof, and methods... | 09/28/2010 |
| 7794751 | Medicament incorporation matrix A coating composition, in both its uncrosslinked and crosslinked forms, for use in delivering a medicament from the surface of a medical device positioned in vivo. Once crosslinked, the coating composition provides a gel matrix adapted to contain the medicament in a... | 09/14/2010 |
| 7718193 | Temperature- and pH-responsive polymer compositions Temperature- and pH-responsive copolymer compositions, and drug delivery devices, conjugates, nanoparticles, and micelles that include the compositions. ... | 05/18/2010 |
| 7651701 | Bone cement composition and method of making the same Disclosed herein is a composition suitable for use in spinal surgery. The composition generally includes a reaction product or settable mixture of first and second components, the first component including a spray-dried inorganic filler, a radical donor, and a pre-p... | 01/26/2010 |
| 7648715 | Colourants encapsulated in polymer matrix Polymeric particles comprising a polymeric matrix and colourant distributed throughout the matrix, wherein the polymeric matrix that has been formed from a blend of monomers comprising a first monomer which is an ethylenically unsaturated ionic monomer and a second ... | 01/19/2010 |
| 7638140 | Adhesive mixture for transdermal delivery of highly plasticizing drugs Transdermal drug delivery patches and methods of their production are described. The patches can be made such that the accommodate highly plasticizing drugs such as selegiline and/or the use of protonated forms of various drugs. ... | 12/29/2009 |
| 7579021 | Drug delivery systems based on degradable cationic siloxanyl macromonomers Matrix controlled diffusion drug delivery systems based on one or more silicon-containing monomers of the general formula: wherein L, X−, n, R1, R2, R3, R4, R5, R6, R7 and V are as set forth herein. ... | 08/25/2009 |
| 7442369 | Compositions of minoxidil Novel compositions comprising minoxidil, a thickening agent, and a pharmaceutically acceptable solvent are presented. Also presented is a process for making a novel gel composition comprising minoxidil, and methods for using the novel compositions for treating and p... | 10/28/2008 |
| 7431943 | Controlled release and taste masking oral pharmaceutical compositions Controlled release and taste masking compositions containing one or more active principles inglobated in a three-component matrix structure, i.e. a structure formed by successive amphiphilic, lipophilic or inert matrices and finally inglobated or dispersed in hydrop... | 10/07/2008 |
| 7425322 | Responsive biomedical composites A responsive polymeric system including a responsive polymeric component capable of undergoing a transition that results in a sharp increase in viscosity in response to a triggering effected at a predetermined body site. The system includes a solid non-ceramic reinf... | 09/16/2008 |
| 7419685 | Process for producing solid dosage forms Solid dosage forms containing at least one polymer binder, at least one active ingredient and, where appropriate, conventional additives, wherein a physiologically tolerated, water-swellable graft copolymer or a mixture of graft copolymers is employed as polymeric b... | 09/02/2008 |
| 7417021 | Biologically active conjugate of a biopolymer and therapeutic agent A biologically active conjugate is disclosed comprising a biopolymer and a therapeutic agent joined by a disulfide bond. The conjugate, when formulated in a pharmaceutical composition with a suitable carrier, has improved in vivo stability and activity, and can be t... | 08/26/2008 |
| 7413752 | Composite hydrogel drug delivery systems Compositions and methods are provided to control the release of relatively low molecular weight therapeutic species through hydrogels by first dispersing or dissolving such therapeutic species within relatively hydrophobic rate modifying agents to form a mixture. Th... | 08/19/2008 |
| 7399739 | Vertebral augmentation composition and method A flowable vertebral augmentation composition for the treatment and repair of a vertebral body defect, e.g., an osteoporotic condition, contains biocompatible, optionally osteoconductive, support elements that are resistant to deformation or fracture under the norma... | 07/15/2008 |
| 7393544 | Dispersion for pulmonary delivery of a bioactive agent Stabilized dispersions are provided for the delivery of a bioactive agent. The dispersions preferably comprise a plurality of perforated microstructures dispersed in a suspension medium that typically comprises a liquid fluorochemical. As density variations between ... | 07/01/2008 |
| 7378109 | Pharmaceutical composition for improving palatability of drugs and process for preparation thereof The present invention discloses compositions, comprising a lipid-polymer matrix to mask the bitter or unpleasant taste of the medicament. The lipid or a blend of lipids, are used in combination with the pH dependent polymer where the said polymer is acid soluble or ... | 05/27/2008 |
| 7368484 | Reverse thermal gels as support for rapid prototyping The present invention relates to novel polymeric compositions that exhibit Reverse Thermal Gelation (RTG) properties for use as Support Materials (SM) in the manufacture of three-dimensional objects. These polymers are Temperature Sensitive Polymers that respond wit... | 05/06/2008 |
| 7364678 | Process for making and process for converting polyolefin fibres The invention relates to a process for making a multi-filament polyethylene yarn via a gel-spinning process, Wherein a spin finish is applied at least once in an amount of 0.1-10 mass % based on the filament, to a filament that contains less than 50 mass % of solven... | 04/29/2008 |
| 7364675 | Self-folding polymer microparticles A method for forming three-dimensional polymeric particulate microstructures through self-folding of thin-film microparticles. Self-folding of two-dimensional polymeric precursors produces various three-dimensional particulate microstructures. Dumpling-like microstr... | 04/29/2008 |
| 7357943 | Pharmaceutical preparation in the form of a suspension comprising an acid-labile active ingredient The present invention relates to the field of pharmaceutical technology and describes a novel pharmaceutical preparation in the form of a suspension comprising an acid-labile active ingredient, in particular an acid-labile proton pump inhibitor. The invention also r... | 04/15/2008 |
| 7326425 | Pharmaceutical formulation composed of a polymer blend and an active compound for time-controlled release A formulation containing a biologically active compound having a structure with hydrogen bonding sites blended with a first polymer having a structure with complementary hydrogen bonding sites and a second polymer that degrades to form degradation products that prom... | 02/05/2008 |
| 7323179 | Methods and compositions for the treatment and prevention of and other bacterial infections The invention features methods and compositions for treatment or prevention of infection by, or disease caused by infection with, certain species of bacteria, including in particular bacteria in which a RAP-type and/or TRAP-type molecule plays a role in pathogenesis... | 01/29/2008 |
| 7318937 | Liquid coating compositions Liquid coating compositions are provided that comprise siloxane containing polymer, volatile polydimethylsiloxane, and aliphatic hydrocarbon. The liquid coating compositions preferably comprise from 18-55 weight % of volatile polydimethylsiloxane, from 5-55 weight %... | 01/15/2008 |
| 7316999 | Glucose dependent release of insulin from glucose sensing insulin derivatives Insulin derivatives having a built-in glucose sensor, capable of delivering insulin from a depot as a function of the glucose concentration in the surrounding medium (e.g. tissue), such that the rate of insulin release from the depot increases with an increased gluc... | 01/08/2008 |
| 7317000 | Glucose-dependent insulins The present invention relates to insulin derivatives having a built-in glucose sensor and a polyol moiety, capable to deliver insulin from an injected depot of an insulin derivative according to the invention as a function of the glucose concentration in the surroun... | 01/08/2008 |
| 7314584 | Polymer gel composition and optical device using the same The present invention provides a polymer gel composition including: at least two polymer compounds which interact with each other to form a polymer complex; and a liquid. One of the polymer compounds forms a three-dimensional crosslinked structure, at least one othe... | 01/01/2008 |
| 7309497 | Injectable pharmaceutical composition for systematic administration of pharmacologically active ingredients The invention relates to novel pharmaceutical compositions for the systemic administration of pharmacologically active ingredients. The invention relates in particular to an injectable pharmaceutical composition comprising (a) a pharmacologically active ingredient i... | 12/18/2007 |
| 7300662 | Drug/drug delivery systems for the prevention and treatment of vascular disease A drug and drug delivery system may be utilized in the treatment of vascular disease. A local delivery system is coated with rapamycin or other suitable drug, agent or compound and delivered intraluminally for the treatment and prevention of neointimal hyperplasia f... | 11/27/2007 |
| 7297673 | Thickener for high-pH aqueous systems An aqueous composition having a pH of at least 10, and comprising from 0.1% to 5% of at least one crosslinked copolymer comprising from 2.5% to 65% (meth)acrylic acid residues, from 10% to 80% C2-C4 alkyl (meth)acrylate residues, from 2% to 25%... | 11/20/2007 |
| 7294347 | Coating compositions for bitterness inhibition The present invention discloses coating compositions with taste masking property, comprising a blend of pH sensitive polymers and optionally a pH independent polymer or a blend of the pH sensitive polymer and pH independent polymer used for taste masking of highly b... | 11/13/2007 |
| 7282218 | pH sensitive polymer for inhibiting transformation in drugs The present invention discloses a substantially amorphous pharmaceutical composition comprising a drug that can exist in a variety of polymorphic forms and a pH sensitive polymer, which inhibits the crystallization of the drug during formulation and reconstitution. ... | 10/16/2007 |
| 7282221 | Antiviral product, use and formulation thereof An antiviral product is comprised of at least three dosages forms, each of which has a different release profile, with the Cmax for the antiviral product being reached in less than about twelve hours. In one embodiment, there is an immediate release dosag... | 10/16/2007 |
| 7282219 | Powdery preparation for transmucosal administration containing a polymeric form of drug and exhibiting improved storage stability A powdery preparation for transmucosal administration comprising a medicine of high molecular weight, a cationic polymer and, as needed, a viscous polymer, further comprising an effective amount of a basic amino acid. The powdery preparation for transmucosal adminis... | 10/16/2007 |
| 7267924 | Top anti-reflective coating polymer, its preparation method and top anti-reflective coating composition comprising the same Disclosed herein are a top anti-reflective coating polymer used in a photolithography process, which is one of the fabrication processes for a semiconductor device, a method for preparing the anti-reflective coating polymer, and an anti-reflective coating compositio... | 09/11/2007 |
| 7267828 | Light stabilized antimicrobial materials Methods of enhancing the photostabilizing of silver in medical materials are described. More particularly, the methods increase the photostabilization of silver in certain materials comprising hydrophilic, amphoteric and anionic polymers by subjecting the polymers t... | 09/11/2007 |
