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| Number | Title | Issue Date |
| 7282218 | pH sensitive polymer for inhibiting transformation in drugs The present invention discloses a substantially amorphous pharmaceutical composition comprising a drug that can exist in a variety of polymorphic forms and a pH sensitive polymer, which inhibits the crystallization of the drug during formulation and reconstitution. ... | 10/16/2007 |
| 7282221 | Antiviral product, use and formulation thereof An antiviral product is comprised of at least three dosages forms, each of which has a different release profile, with the Cmax for the antiviral product being reached in less than about twelve hours. In one embodiment, there is an immediate release dosag... | 10/16/2007 |
| 7279176 | Nitric oxide-producing hydrogel materials Hydrogels releasing or producing NO, most preferably photopolymerizable biodegradable hydrogels capable of releasing physiological amounts of NO for prolonged periods of time, are applied to sites on or in a patient in need of treatment thereof for disorders such as... | 10/09/2007 |
| 7279174 | Stent coatings comprising hydrophilic additives A coating for implantable medical devices and a method for fabricating thereof are disclosed. The coating includes a mixture of a hydrophobic polymer and a polymeric hydrophilic additive, wherein the hydrophobic polymer and the hydrophilic additive form a physically... | 10/09/2007 |
| 7279597 | Phenyl amine carboxylic acid compounds and compositions for delivering active agents Phenyl amine carboxylic acid compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. ... | 10/09/2007 |
| 7279664 | Resonator for medical device A resonator device including an induction coil, a conductive member positioned adjacent the induction coil, and a dielectric layer between at least a portion of the induction coil and the conductive member to form a capacitor structure. In one embodiment, the conduc... | 10/09/2007 |
| 7276256 | Cosmetic or healing gel for application to the human skin A gel formed from an intimate mixture of polyvinyl alcohol, an alkaline or alkaline earth metal borate, water and an alginate and/or a carrageenan, having cryogenic characteristics, substances with cosmetic and/or pharmacological characteristics being easily dispers... | 10/02/2007 |
| 7273756 | Method for chondrocyte expansion with phenotype retention The present invention provides a method that maintains chondrocyte phenotype during serial expansion by culturing a population of chondrocytes in a defined serum-free culture medium containing cytokines and on a substrate that is modified by covalent attachment of h... | 09/25/2007 |
| 7273722 | Neurotoxins with enhanced target specificity Modified neurotoxins that contain protease cleavage sites susceptible uniquely to proteases present in certain tissues are described. The toxins can be selectively activated by proteases in muscle or selectively inactivated by proteases in blood. ... | 09/25/2007 |
| 7273734 | Process for producing a polyester A process for producing a polyester, the process comprising the steps of (1) fermenting a saccharide with a microorganism to obtain at least one substituted α-hydroxy acid represented by the formula: HO—CHR—COOH (wherein R represents a hydrocarbon group having ... | 09/25/2007 |
| 7270834 | Pharmaceutical composition comprising dimethylsulfoxide and ozone A pharmaceutical composition to be externally applied as a topical preparation for treating several diseases, the composition comprising dimethylsulfoxide (DMSO) and ozone. A method for obtaining the composition by ozonizing DMSO and a method for treating diseases b... | 09/18/2007 |
| 7267828 | Light stabilized antimicrobial materials Methods of enhancing the photostabilizing of silver in medical materials are described. More particularly, the methods increase the photostabilization of silver in certain materials comprising hydrophilic, amphoteric and anionic polymers by subjecting the polymers t... | 09/11/2007 |
| 7268114 | Protein and process for preparing the same A protein having amino acid sequence in SEQ ID NO: 1 of the Sequence Listing derived from human MP52, and a dimer protein thereof. A homodimer protein described above can be obtained by constructing a plasmid containing DNA coding amino acid sequence in SEQ ID NO: 1... | 09/11/2007 |
| 7264825 | Pharmaceutical preparation with retarding active ingredient release, method for its production and its use The invention describes pharmaceutical preparations with retarding active ingredient release, which consist of mixtures of powdery teicoplanin and at least one powdery, water soluble salt form of gentamicin, clindamycin, kanamycin, amikacin, tobramycin, vancomycin, ... | 09/04/2007 |
| 7265257 | Absorbent articles comprising a bodily exudate modifying agent and a film-forming skin care formulation Absorbent articles having enhanced absorption of bodily exudates are disclosed. The absorbent articles comprise a bodily exudate modifying agent and a skin care formulation. The bodily exudate modifying agent is capable of reducing the viscosity of bodily exudates s... | 09/04/2007 |
| 7261875 | Dendritic poly (amino acid) carriers and methods of use The present invention concerns a design for dendritic poly(amino acid) polymer carriers, also known as nonlinear polymers, and their applications. These dendritic poly(amino acid) carriers have multiple functional groups at the polymer surface. In addition, they hav... | 08/28/2007 |
| 7261867 | Production of silver sulfate grains using organo-sulfate or organo-sulfonate additives An aqueous precipitation process for the preparation of particles comprising primarily silver sulfate, comprising reacting an aqueous soluble silver salt and an aqueous soluble source of inorganic sulfate ion in an agitated precipitation reactor vessel and precipita... | 08/28/2007 |
| 7256180 | Compositions and methods for inducing activation of dendritic cells Compositions induce the activation of dendritic cells comprising a polynucleotide, such as viruses, RNA, DNA, plasmid DNA, or derivatives thereof and at least one block copolymer of alkylethers. The present invention further relates to compositions for inducing the ... | 08/14/2007 |
| 7252838 | Drug releasing elastic band and method A ligating band according to the present invention comprises an elastomeric layer and an inner drug releasing layer. The inner drug releasing layer includes a therapeutic agent, for example a chemotherapeutic agent for treating a mucosa, polyp or other growth. A lig... | 08/07/2007 |
| 7253150 | Gene delivery vehicle expressing the aptosis-inducing proteins VP2 and/or apoptin The invention relates to gene delivery vehicles which comprise nucleic acid molecules encoding apoptosis-inducing proteins VP2 and/or apoptin (VP3) like activity. VP2 and VP3 are viral proteins of the Chicken Anaemia Virus. Also, the invention relates to anti-tumor ... | 08/07/2007 |
| 7250177 | Multiblock biodegradable hydrogels for drug delivery and tissue treatment Gel-forming macromers including at least four polymeric blocks, at least two of which are hydrophobic and at least one of which is hydrophilic, and including a crosslinkable group are provided. The macromers can be covalently crosslinked to form a gel on a tissue su... | 07/31/2007 |
| 7247314 | Biocompatible material composition adaptable to diverse therapeutic indications A biocompatible material genus serves as the foundation for multiple material composition species, each adapted to a specific therapeutic indication. ... | 07/24/2007 |
| 7244445 | Conformable, absorbable, solid composite preforms and their use for bone tissue engineering The present invention is directed to an absorbable, conformable composite preform for use in making a solid bone filler which is an absorbable mixture of oppositely charged, solid microparticulate polyelectrolytes encased in a sealed, flexible, absorbable copolyeste... | 07/17/2007 |
| 7244442 | Method for making devices using polyhydroxyalkanoate having pyrogen removed Polyhydroxyalkanoates (PHAs) from which pyrogen has been removed are provided for use in numerous biomedical applications. PHAs which have been chemically modified to enhance physical and/or chemical properties, for targeting or to modify biodegradability or clearan... | 07/17/2007 |
| 7244443 | Polymers of fluorinated monomers and hydrophilic monomers A polymer of fluorinated monomers and hydrophilic monomers is provided. It is also provided a polymer blend that contains a polymer of fluorinated monomers and another biocompatible polymer. The polymer of fluorinated monomers or polymer blend described herein and o... | 07/17/2007 |
| 7244706 | Antimicrobial/endotoxin neutralizing polypeptide The present invention provides a therapeutic method for treating or preventing a disease resulting from a microbial infection in an individual using an antimicrobial polypeptide. The present invention also provides a method of potentiating the therapeutic action of ... | 07/17/2007 |
| 7244842 | Amorphous hydrate of a cephalosporin antibiotic A process for the preparation of cefdinir of the formula (I) the said process comprising the steps of: i) condensing 7-amino-3-cephem-4-carboxylic acid of the formula (XII) wherein R1 is as defined above with compound of the formula (XIII) in the presence of a terti... | 07/17/2007 |
| 7241813 | End-capped polymers and compositions containing such compounds End-capped polymers, methods for making those end-capped polymers and compositions containing those end-capped polymers are disclosed. One of the disclosed end-capped copolymers has the formula: and may be combin... | 07/10/2007 |
| 7241835 | Cosmetic compositions comprising silicone gels Methods for making homogenized cosmetic formulations comprising a silicone gel. ... | 07/10/2007 |
| 7241458 | Antiviral compositions The present invention is concerned with pharmaceutical compositions of antiviral compounds which can be administered to a mammal, in particular a human, suffering from a viral infection. These compositions comprise particles obtainable by melt-extruding a mixture co... | 07/10/2007 |
| 7235587 | Diesters containing two crylene or fluorene moieties, sunscreen compositions containing the same, and methods of photostabilizing a sunscreen compositions containing the same Diesters that include one or more of a crylene and/or a fluorene moiety, and sunscreen compositions including a mixture of a photoactive compound and one or more of a diester that includes one or more of a crylene and/or a fluorene moiety are described herein. Also ... | 06/26/2007 |
| 7235260 | Pharmaceutical compositions of a sparingly soluble glycogen phosphorylase inhibitor Pharmaceutical compositions of a particularly effective sparingly soluble glycogen phosphorylase inhibitor are disclosed, as well as methods of making such compositions and dosage forms from such compositions. ... | 06/26/2007 |
| 7235592 | PVA hydrogel The present invention provides methods of making covalently crosslinked vinyl polymer hydrogels having advantageous physical properties, and covalently crosslinked vinyl polymer hydrogel compositions made by such methods, as well as articles of manufacture comprisin... | 06/26/2007 |
| 7235259 | Pharmaceutical compositions of cholesteryl ester transfer protein inhibitors A pharmaceutical composition comprises a solid amorphous dispersion of a cholesteryl ester transfer protein inhibitor and a concentration-enhancing polymer. ... | 06/26/2007 |
| 7235099 | Sphenoid sinus stent A stent specifically designed for use in treating chronic sphenoid sinusitis comprises a soft compressible plastic tube of a predetermined diameter having a proximal end, a distal end and a lumen extending therebetween. The stent has a generally hemispherical hollow... | 06/26/2007 |
| 7234365 | Methods and systems for dissolution testing Methods and systems for determining a dissolution profile of a sample material, and for solubilization screening of a library defined by an array comprising multiple sample materials are disclosed. The methods and systems are particularly advantageous for sampling a... | 06/26/2007 |
| 7232802 | Compositions and methods for promoting myocardial and peripheral angiogenesis Methods, compositions and devices are disclosed for use in growing new blood vessels to restore or improve blood flow to ischemic tissues and organs of the body. Compositions comprising IGD peptides, particularly GGIGDGG, are able to induce migration in human endoth... | 06/19/2007 |
| 7229959 | Supplemented fibrin matrix delivery systems This invention provides supplemented and unsupplemented tissue sealants as well as methods for their production and use thereof. Disclosed are tissue sealants supplemented with at least one antibody. The composition may be further supplemented with, for example, one... | 06/12/2007 |
| 7229973 | pH-sensitive polymeric micelles for drug delivery Mixed micelles containing poly(L-histidine)-poly(ethylene glycol) block copolymer and poly(L-lactic acid)-poly(ethylene glycol) block copolymer are a pH-sensitive drug carrier that release the drug in an acidic microenvironment, but not in the blood. Since the micro... | 06/12/2007 |
| 7229642 | Amino acid modulated extended release dosage form Disclosed herein is a oral extended release dosage form comprising a plurality of granules of an effective amount of a pharmaceutically active compound, at least one amino acid, and an intragranular polymer in which the granule is dispersed within a hydrophilic extr... | 06/12/2007 |
