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| Number | Title | Issue Date |
| 7670621 | Transdermal administration of (R)-3,3-diphenylpropylamin-monoesters The invention relates to a device for transdermally administering a compound of formula (I), wherein A represents hydrogen or deuterium, R represents a group selected among C1-4alkyl, C3-10cycloalkyl, or phenyl, each of which can be substituted... | 03/02/2010 |
| 7670622 | Composition for in vivo vessel repair The present invention relates to a biocompatible polymer composition, suitable for in vivo vessel repair, comprising a matrix pre-polymer, a filler and a curing agent, wherein said composition wherein said biocompatible polymer composition is curable in the presence... | 03/02/2010 |
| 7658946 | Solid supports functionalized with phosphorus-containing dendrimers, process for preparing them and uses thereof The present invention relates to solid supports functionalized with phosphorus-containing dendrimers, to a process for preparing them, to their use for preparing biochips and to the uses of these biochips, in particular for immobilizing molecules of interest, especi... | 02/09/2010 |
| 7655258 | Biodegradable copolymer, and polymeric micelle composition containing the same A biodegradable copolymer with a core block comprising bioresorbable hydrophobic polyester segment and from 3 to 10 shell blocks comprising hydrophilic polyethylene glycol segment. The hydrophobic polyester segment and each of the hydrophilic polyethylene glycol seg... | 02/02/2010 |
| 7641917 | Method of encapsulating an active substance The invention provides a method of encapsulating an active substance in an interpolymer complex, to make an encapsulated product in particulate form. The method comprises forming a mixture of a supercritical fluid, an interpolymer complex and an active substance and... | 01/05/2010 |
| 7550155 | Aqueous pharmaceutical compositions of 2,6-diisopropylphenol (propofol) and their uses The present invention provides aqueous pharmaceutical compositions containing a lipophilic therapeutic agent. In particular, the invention provides aqueous pharmaceutical compositions containing the compound 2,6-diisopropylphenol (propofol). Preferred compositions o... | 06/23/2009 |
| 7517538 | Solid supports functionalised with phosphorus dendrimers, method for preparing same and uses thereof The present invention relates to solid supports functionalized with phosphorus-containing dendrimers, to a process for preparing them, to their use for preparing biochips and to the uses of these biochips, in particular for immobilizing molecules of interest, especi... | 04/14/2009 |
| 7459172 | Method of making a protein polymer and uses of the polymer A polymer is prepared by self-assembly of a plurality of monomeric polypeptide units. The polymer tends to form a nanotube and is capable of encapsulating a particular drug molecule. Once encapsulated in the polymer of the present invention, the drug molecule may be... | 12/02/2008 |
| 7442387 | Pharmaceutical composition for controlled release of active substances and manufacturing method thereof The present invention pertains to a sized product, which contains a drug, polyethylene oxide with a molecular weight of 2,000,000 or higher, and a specific size controlling agent for polyethylene oxide (substance with the appropriate plasticity and binding force) an... | 10/28/2008 |
| 7438928 | Topical gel matrix A topical gel matrix that can be used alone or combination with a medication entrapped therein. The gel matrix is dispersible in water. The gel may have the following composition: oil, water or aqueous solution; solvents, surfactants and/or detergents; and a polymer... | 10/21/2008 |
| 7435790 | Dihydroxypropyl cysteine peptide and agent containing this peptide The invention relates to a S-(2,3-dihydroxypropyl)-cysteine peptide which has two long-chain fatty acids bonded in the form of esters at the dihydroxypropyl group, and which has the following sequence: DhcGN NDE SNI SFK EK. The invention relat... | 10/14/2008 |
| 7431943 | Controlled release and taste masking oral pharmaceutical compositions Controlled release and taste masking compositions containing one or more active principles inglobated in a three-component matrix structure, i.e. a structure formed by successive amphiphilic, lipophilic or inert matrices and finally inglobated or dispersed in hydrop... | 10/07/2008 |
| 7425528 | Stabilization of granules The present invention relates to granules comprising a core matrix and one or more coatings, wherein the core matrix comprises: An active compound, a synthetic polymer, where the amount of polymer added is 0.1 to 10% by weight of the matrix and one or more antioxida... | 09/16/2008 |
| 7425322 | Responsive biomedical composites A responsive polymeric system including a responsive polymeric component capable of undergoing a transition that results in a sharp increase in viscosity in response to a triggering effected at a predetermined body site. The system includes a solid non-ceramic reinf... | 09/16/2008 |
| 7419685 | Process for producing solid dosage forms Solid dosage forms containing at least one polymer binder, at least one active ingredient and, where appropriate, conventional additives, wherein a physiologically tolerated, water-swellable graft copolymer or a mixture of graft copolymers is employed as polymeric b... | 09/02/2008 |
| 7417021 | Biologically active conjugate of a biopolymer and therapeutic agent A biologically active conjugate is disclosed comprising a biopolymer and a therapeutic agent joined by a disulfide bond. The conjugate, when formulated in a pharmaceutical composition with a suitable carrier, has improved in vivo stability and activity, and can be t... | 08/26/2008 |
| 7413747 | Transdermal therapeutic system for treating Parkinsonism A transdermal therapeutic system (TTS) comprises a silicone-based polymer adhesive system having distributed therein (−)-5,6,7,8-tetrahydro-6-[propyl-[2-(2-thienyl)ethyl]amino]-1-naphthalenol free base in an amount of about 5% to 40% by weight. The adhesive system... | 08/19/2008 |
| 7413753 | Calcium phosphate delivery vehicles for osteoinductive proteins A composition for delivery of osteogenic proteins is disclosed. The composition comprises an osteogenic protein, a calcium phosphate material as a carrier, and an effective amount of an effervescent agent. Methods of making the compositions and methods of using the ... | 08/19/2008 |
| 7413750 | Process for producing solid oral dosage forms with sustained release of active ingredient The present invention relates to a process for producing solid oral dosage forms with sustained release of active ingredient, comprising at least one active ingredient, a preformulated mixture of polyvinyl acetate and polyvinylpyrrolidone, where appropriate, water-s... | 08/19/2008 |
| 7413752 | Composite hydrogel drug delivery systems Compositions and methods are provided to control the release of relatively low molecular weight therapeutic species through hydrogels by first dispersing or dissolving such therapeutic species within relatively hydrophobic rate modifying agents to form a mixture. Th... | 08/19/2008 |
| 7410947 | Osteogenic devices and methods of use thereof for repair of endochondral bone and osteochondral defects Disclosed herein are improved osteogenic devices and methods of use thereof for repair of bone and cartilage defects. The devices and methods promote accelerated formation of repair tissue with enhanced stability using less osteogenic protein than devices in the art... | 08/12/2008 |
| 7407670 | Solid dispersions comprising two different polymer matrixes Present invention provides solid dispersions comprising a poorly soluble bioactive compound dispersed in a polymer matrix characterized in that the polymer matrix comprises more than one polymer. Said solid dispersions effectively stabilize the dispersed compound wh... | 08/05/2008 |
| 7407671 | Temperature controlled solute delivery system A system for delivering solute to a target location within a mammalian body, the system including a medical device, a thermosensitive cellulose gel structure over the medical device, and a biologically active solute within said gel structure. The gel structure deswe... | 08/05/2008 |
| 7405042 | Method of extracting nucleic acid or protein using dendrimers and dendrimer-compositional substances The present invention relates to a method of extracting nucleic acid or protein, in which multi-layer dendrimers are formed on the surface of fine particles, amino radicals for capturing nucleic acid or protein are formed on the surface of these dendrimers, and nucl... | 07/29/2008 |
| 7399483 | Carrier with solid fibrinogen and solid thrombin The present invention relates to a solid composition useful for tissue gluing, tissue sealing and haemostasis consisting essentially of a) a carrier which has at least one of the following physical properties: elasticity module in the range of 5-100 N/cm, density of... | 07/15/2008 |
| 7393547 | Antimicrobial elastomer composition and method for making A method for making an elastomeric material containing an antimicrobial composition such as a dispersion of silver oxide that is suitable for implantation within the body. The elastomer made in accordance with this method extends the amount of work-time available fo... | 07/01/2008 |
| 7384626 | Functionalized dendritic polymers for the capture and neutralization of biological and chemical agents The present invention describes compositions and methods for sorbing and/or destroying dangerous substances such as chemical and biological warfare agents. The present invention relates to dendritic polymers, specifically, to quaternary ammonium functionalized dendr... | 06/10/2008 |
| 7374774 | Electroprocessed material made by simultaneously electroprocessing a natural protein polymer and two synthetic polymers The invention is directed to novel compositions comprising an electroprocessed material and a substance, their formation and use. The electroprocessed material can, for example, be one or more natural materials, one or more synthetic materials, or a combination ther... | 05/20/2008 |
| 7375096 | Method of preparing a supramolecular complex containing a therapeutic agent and a multi-dimensional polymer network A method of preparing a supramolecular complex containing at least one therapeutic agent and a multi-dimensional polymer network is described. A supramolecular complex prepared by a method of the invention is described. A method of treatment by administering a thera... | 05/20/2008 |
| 7368125 | Amphiphilic polymers for medical applications The present invention is directed to medical devices or pharmaceutical compositions, each containing a synthetic, bioabsorbable, biocompatible polymer that is the reaction product of a polybasic acid or derivative thereof, a monoglyceride, and a polyether. ... | 05/06/2008 |
| 7364748 | Controlled morphologies in polymer drug for release of drugs from polymer films The present invention includes a drug release system. The drug release system comprises a bulk polymer phase and a polymeric drug-enriched phase within the bulk polymer phase. At least one drug is incorporated into the drug-enriched phase. ... | 04/29/2008 |
| 7364859 | Methods of using bioelastomers Bioelastomers are disclosed for use in methods of binding compounds including immunoassay methods, in biosensors and methods or regenerating biosensors, and in methods for targeting the delivery of a compound to a particular location within an animal subjects. In ge... | 04/29/2008 |
| 7364752 | Solid dispersion pharamaceutical formulations A pharmaceutical composition is disclosed which comprises a solid dispersion of an HIV protease inhibitor in a water soluble carrier, such as PEG, having enhanced bioavailability and improved dissolution properties. The solid dispersion may optionally be encapsulate... | 04/29/2008 |
| 7364586 | C3 exoenzyme-coated stents and uses thereof for treating and preventing restenosis This invention provides a stent for implantation in a blood vessel or other tissue, wherein the stent is coated with or contains C3 exoenzyme, a chimeric version thereof or an inhibitor of RhoA. This invention also provides a method for treating or inhibiting the on... | 04/29/2008 |
| 7361794 | Zone reactor In a method of converting alkanes to their corresponding alcohols and ethers a vessel comprises a hollow, unsegregated interior defined first, second, and third zones. In a first embodiment of the invention oxygen reacts with metal bromide in the first zone to provi... | 04/22/2008 |
| 7361691 | Method of treating cancers using β-lapachone or analogs or derivatives thereof Cancers and/or malignancies can be treated by administration of a cell cycle checkpoint activator, which is preferably β-lapachone, or a derivative or analog thereof, combined with an oncogenic kinase modulator, preferably imatinib. This combination of the cell cyc... | 04/22/2008 |
| 7361715 | Polymer additives for powder coatings Star polymers prepared by reacting a highly branched polymer and either a lactone or lactam are disclosed. These star polymers find particular application as additives for powder coating compositions, to improve various performance properties thereof. Powder coating... | 04/22/2008 |
| 7357943 | Pharmaceutical preparation in the form of a suspension comprising an acid-labile active ingredient The present invention relates to the field of pharmaceutical technology and describes a novel pharmaceutical preparation in the form of a suspension comprising an acid-labile active ingredient, in particular an acid-labile proton pump inhibitor. The invention also r... | 04/15/2008 |
| 7354600 | Muco-adhesive polymers, use thereof and method for producing the same Mucoadhesive polymers, the use thereof and a production method therefor. Mucoadhesive polymers assembled of not more than 10 different monomers and comprising at least one non-terminal thiol group, as well as drugs containing these polymers are described. ... | 04/08/2008 |
| 7354531 | Polymer electrolyte composition A composition for use as a polymer electrolyte, wherein said composition includes one or more polar materials and one or more polyesters of formula III, wherein each unit A may be identical or different and is of the struct... | 04/08/2008 |