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Class 424/473 - With porous, perforated, apertured, or sieved layer (e.g., dialyzing layer, microporous layer, etc.)


Subclass of Class 424 - Drug, bio-affecting and body treating compositions
Definition: Subject matter in which a sustained or differential release
No. of patents: 630
Last issue date: 05/29/2012


1                      
NumberTitleIssue Date
8187633Controlled release coated tablets having prolonged gastric retention
The present invention relates to a tablet composed of a core and a coating; said core is formed by two or more layers, wherein at least one of them contains an active agent (3). Wherein one of said layers is formulated as a swellable composition (2), t...
05/29/2012
8158150Two-piece, internal-channel osmotic delivery system flow modulator
An osmotic delivery system flow modulator includes an outer shell constructed and arranged for positioning in an opening, an inner core inserted in the outer shell, and a fluid channel having a spiral shape defined between the outer shell and the inner core. The flu...
04/17/2012
8084059Antidepressant dosage form
The invention pertains to a dosage form 10 and to administering an antidepressant medicament 16 for an extended period of time in a rate-known dose. ...
12/27/2011
8052996Two-piece, internal-channel osmotic delivery system flow modulator
An osmotic delivery system flow modulator includes an outer shell constructed and arranged for positioning in an opening, an inner core inserted in the outer shell, and a fluid channel having a spiral shape defined between the outer shell and the inner core. The flu...
11/08/2011
7959946Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
A pharmaceutical dosage form comprising a controlled release component comprising an antihyperglycemic drug in combination with a second component comprising a thiazolidinedione derivative is herein disclosed and described. ...
06/14/2011
7923027Process
The present invention relates to a process using ultrasonic cutting for the preparation of an oral delivery device comprising a core which includes a pharmaceutically active agent covered by an outer coating which includes one or more openings communicating from the...
04/12/2011
7879354Rapidly disintegrating gelatinous coated tablets
The present invention relates to an improved gelatinous coated dosage form having two end regions coated with gelatinous materials and an exposed circumferential band. Openings are provided in at least the exposed band to reveal the core material. The invention also...
02/01/2011
7879355Method and system for treatment of eating disorders
The invention comprises a gastric device having a pouch formed from a degradable film. Preferably, the pouch contains a gas producing material. The gastric device hydrates within a patient's stomach and the gas producing material expands the device to a greater volu...
02/01/2011
7875293Biointerface membranes incorporating bioactive agents
A biointerface membrane for an implantable device including a nonresorbable solid portion with a plurality of interconnected cavities therein adapted to support tissue ingrowth in vivo, and a bioactive agent incorporated into the biointerface membrane and adapted to...
01/25/2011
7807197Composite dosage forms having an inlaid portion
A dosage form comprises at least one active ingredient, a first portion which comprises an exterior surface and one or more cavities defining at least one interior surface having indentations and an exterior surface, and a second molded portion which is inlaid into ...
10/05/2010
7736668System for delaying drug delivery up to seven hours
A dosage form is disclosed comprising means for delaying the delivery of drug from the dosage form following the administration of the dosage form to a patient in need of drug therapy. ...
06/15/2010
7731989Gastric retained gabapentin dosage form
A method of treatment for epilepsy and other disease states is described, which comprises the delivery of gabapentin in a gastric retained dosage form. ...
06/08/2010
7713550Controlled release sodium valproate formulation
Disclosed is a controlled release formulation comprising valproic acid, pharmaceutically acceptable salt thereof, amide thereof, or derivative thereof. ...
05/11/2010
7709025Enteric coatings for orally ingestible substrates
Enteric film coating systems for orally ingestible substrates such as pharmaceutical tablets and dietary supplements are disclosed. In preferred aspects, the enteric film coatings include an ethylcellulose dispersion and a substantially gastro-insoluble pore former ...
05/04/2010
7682629Floating pharmaceutical composition comprising an active phase and a non-active phase
The invention concerns a floating pharmaceutical composition consisting of at least a first phase comprising at least a high dose active principle combined with one or several carriers and at least a second phase comprising at least a gas-generating system. The inve...
03/23/2010
7655257Sustained delivery of an active agent using an implantable system
The invention is directed to a device for delivering an active agent formulation for a predetermined administration period. An impermeable reservoir is divided into a water-swellable agent chamber and an active agent formulation chamber. Fluid from the environment i...
02/02/2010
7514100Controlled release hydrocodone formulations
A solid oral controlled-release dosage form of hydrocodone is disclosed, the dosage form comprising an analgesically effective amount of hydrocodone or a pharmaceutically acceptable salt thereof, and controlled release material. ...
04/07/2009
7438927Methods of treatment using a gastric retained gabapentin dosage
A method of treatment for epilepsy and other disease states is described, which comprises the delivery of gabapentin in a gastric retained dosage form. ...
10/21/2008
7419684System and method for manufacturing oral osmotic drug delivery devices, and methods of administering same
A system and method for manufacturing oral osmotic drug delivery devices including the use of a mathematical model in deriving relationships between parameters used in manufacturing the devices for a desired release rate of the active drug substance contained therei...
09/02/2008
7413751Methods of treatment using a gastric retained losartan dosage
A method of treatment for hypertension and other disease states is described, which comprises the delivery of losartan in a gastric retained dosage form. ...
08/19/2008
7387792Pharmaceutical composition for compressed annular tablet with molded triturate tablet for both intraoral and oral administration
New pharmaceutical compositions in unit dosage form are disclosed for both intraoral and oral administration to a patient, said unit dosage form configured to be placed intraorally of said patient, which comprises: (a) as a first p...
06/17/2008
7350479System and method for controlling growth of aquatic plants utilizing bio-eroding means implanted in triploid grass carp
An “implant and forget” device for interacting with biota after a pre-established time period. Preferably, the biota are fauna and more particularly fish. In select embodiments, the device comprises packaging enclosing apparatus for timing interaction via openin...
04/01/2008
7351695Topiramate salts and compositions comprising and methods of making and using the same
The invention encompasses novel salts of topiramate, and pharmaceutically acceptable polymorphs, solvates, hydrates, dehydrates, co-crystals, anhydrous, or amorphous forms thereof, as well as pharmaceutical compositions and pharmaceutical unit dosage forms containin...
04/01/2008
7341986Cleaning concentrate consisting of extra virgin olive oil and isopropyl alcohol
The invention, a stable composition of matter, has a 2 step method to make (maintain the same equalities in increased batches). Step #1. 0.4167 Extra Virgin Olive Oil First Cold Pressed, which is a high quality olive oil, 0.5833 IPA, Isopropyl Alcohol 70%, shake to ...
03/11/2008
7342596Method for direct xerography
A system for printing is described. The system uses at least one cantilever, and more typically a plurality of cantilever to transfer charge, either to or from a dielectric surface. The resulting charge distribution represents an image. Toner deposited over the diel...
03/11/2008
7332183Multilayer dosage forms containing NSAIDs and triptans
The present invention is directed to multilayer pharmaceutical tablets in which an NSAID and a triptan are present in separate and distinct layers. The layers are in a side-by-side configuration, which allows the dissolution of triptan and NSAID to occur independent...
02/19/2008
7332525Method of treatment of prostate cancer and composition for treatment thereof
A method and composition for the treatment of prostate cancer comprises an effective amount of a nonsteroidal antiandrogen and an effective amount of a selective estrogen receptor modulator. The composition has fewer side effects such as breast tenderness and gyneco...
02/19/2008
7329418Pharmaceutical tablets having height greater than width
An immediate release compressed pharmaceutical tablet that has two or more segments and a top and a bottom and has a height that exceeds the width of the tablet. The height is measured vertically from the top to the bottom of the tablet while it is in the tablet die...
02/12/2008
7329412Antimicrobial medical devices containing chlorhexidine free base and salt
The present disclosure invention relates to medical devices treated with a solution comprising one or more solvents and a combination of chlorhexidine free base and a water-soluble chlorhexidine salt in a weight/weight ratio of between about 1:1 to about 1:5, prefer...
02/12/2008
7325903Quill-jet printer
A system for depositing a material is described. The system uses at least one cantilever, and more typically a plurality of cantilever to transfer small amounts of material from a source of material to a substrate surface. One application for the system is a printin...
02/05/2008
7323192Immediate release tablet
An immediate release tablet is provided. The tablet comprises at least 60 weight % of an active ingredient and powdered wax having a melting point greater than about 90° C. The tablet may advantageously be produced by direct compression. Although the wax is hydroph...
01/29/2008
7318935Pharmaceutical tablets with active and inactive segments
An immediate release compressed pharmaceutical tablet that has two or more segments and a top and a bottom and has a height that exceeds the width of the tablet. The height is measured vertically from the top to the bottom of the tablet while it is in the tablet die...
01/15/2008
7316821Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer
A stabilized solid controlled release dosage form having a coating derived from an aqueous dispersion of ethylcellulose is obtained by overcoating a substrate including a therapeutically active with an aqueous dispersion of ethylcellulose and then curing the coated ...
01/08/2008
7316819Oral peptide pharmaceutical dosage form and method of production
A pharmaceutical composition for oral delivery of a peptide is in the form of a lamination having at least two layers. The first layer of the lamination includes at least one pharmaceutically acceptable pH-lowering agent. The second layer includes a therapeutically ...
01/08/2008
7313917Volume phase transition to induce gel movement
Movement of a gel structure is propagated by successively applying external stimuli to cause volume phase transition in the gel structure by alternately causing the gel structure to collapse and swell to move the center of mass of the gel structure in the direction ...
01/01/2008
7300668System for manufacturing controlled release dosage forms, such as a zero-order release profile dosage form manufactured by three-dimensional printing
The present invention includes controlled release dosage forms and methods of designing and manufacturing dosage forms to obtain specific release profiles, for example, zero-order release profiles, escalating release profiles or decreasing release profiles. The dosa...
11/27/2007
7300662Drug/drug delivery systems for the prevention and treatment of vascular disease
A drug and drug delivery system may be utilized in the treatment of vascular disease. A local delivery system is coated with rapamycin or other suitable drug, agent or compound and delivered intraluminally for the treatment and prevention of neointimal hyperplasia f...
11/27/2007
7294345Otorhinological delivery device
The invention relates to an otorhinological delivery device comprising at least one pharmaceutically active agent. According to the invention the device comprises a core comprising said at least one pharmaceutically active agent wherein said core is made of an elast...
11/13/2007
7291312Ozone removing material and method for preparing the same
An object of the present invention is to solve problems of conventional ozone-scavenging materials and to provide an ozone-scavenging material capable of effectively decomposing/removing ozone at low cost. To attain the above object, the present invention provides a...
11/06/2007
7286149Direct xerography system
A system for printing is described. The system uses at least one cantilever, and more typically a plurality of cantilever to transfer charge, either to or from a dielectric surface. The resulting charge distribution represents an image. Toner deposited over the diel...
10/23/2007
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