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| Number | Title | Issue Date |
| 8163306 | Oral drug delivery system An oral drug delivery system comprising a coated tablet having one or more surfaces. The coated tablet further comprises a core and a coating surrounding the core. The core comprises an active ingredient composition comprising at least one active ingredient and a ph... | 04/24/2012 |
| 8124126 | Pharmaceutical compositions Methods and compositions are provided which comprise effective amounts of analgesic to treat a subject, including reducing or eliminating an adverse effect associated with the analgesic. ... | 02/28/2012 |
| 8084058 | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative A pharmaceutical dosage form comprising a controlled release component comprising an antihyperglycemic drug in combination with a second component comprising a thiazolidinedione derivative and a disintegrating agent is herein disclosed and described. The dosage form... | 12/27/2011 |
| 8071130 | Solid preparation The present invention intends to provide a solid preparation which contains an insulin sensitizer and an active ingredient other than an insulin sensitizer, and exhibits dissolution behavior of an insulin sensitizer similar to that of an insulin sensitizer from “a... | 12/06/2011 |
| 7964216 | Spaced drug delivery system The present invention provides to a method of administration of two or more therapeutically active agents comprising orally administering to a patient a spaced drug delivery system, wherein the time of release of the two or more therapeutically active agents is desi... | 06/21/2011 |
| 7951400 | Coated tablet formulation and method A coated tablet formulation is provided which includes a medicament such as the DPP4-inhibitor, saxaglipitin or its HCl salt, which is subject to intra-molecular cyclization, which formulation includes a tablet co... | 05/31/2011 |
| 7927625 | Sugar-coated agent A sugar-coated agent that includes a core, a film layer that mainly includes a film component, the outer surface of the core being coated with the film layer, a sugar coating layer that mainly includes a sugar coating component, the outside of the film layer being c... | 04/19/2011 |
| 7842309 | Tamper-resistant oral opioid agonist formulations Disclosed is an oral dosage form comprising (i) an opioid agonist in releasable form and (ii) a sequestered opioid antagonist which is substantially not released when the dosage form is administered intact. ... | 11/30/2010 |
| 7820201 | System for manufacturing controlled release dosage forms, such as zero-order release profile dosage form manufactured by three-dimensional printing The present invention includes controlled release dosage forms and methods of designing and manufacturing dosage forms to obtain specific release profiles, for example, zero-order release profiles, escalating release profiles or decreasing release profiles. The dosa... | 10/26/2010 |
| 7776358 | Extended release venlafaxine besylate tablets Venlafaxine besylate is formulated into an extended release tablet in high loading rates by use of a coating that contains ammonio methacrylate copolymer(s). ... | 08/17/2010 |
| 7713549 | Extended release perforated tablet A tablet for the controlled release of a pharmaceutically active ingredient. The tablet is in the form of coated DST's and MLDST's so that immediate release or time-delayed release can be achieved. Further, such extended release DST's and MLDST's may provide zero or... | 05/11/2010 |
| 7585520 | Compositions containing both sedative and non-sedative antihistamines and sleep aids Compositions containing both a sedative compound and a non-sedative antihistamine are provided. More particularly, compositions for administration at bedtime containing a sedating antihistamine or other sedating compound in immediate release form and a non-sedating ... | 09/08/2009 |
| 7488497 | Oral pharmaceutical dosage forms comprising a proton pump inhibitor and a NSAID An oral pharmaceutical dosage form comprising an acid susceptible proton pump inhibitor and one or more NSAIDs in a fixed formulation, wherein the proton pump inhibitor is protected by an enteric coating layer. The fixed formulation is in the form of an enteric coat... | 02/10/2009 |
| 7488498 | Antidiabetic preparation for oral administration There is provided a single preparation which directly decreases both of the post prandial blood glucose level and the fasting blood glucose level close to normal levels, by release-sustaining a drug capable of decreasing the post prandial blood glucose level of diab... | 02/10/2009 |
| 7482022 | Palatable chewable tablet A palatable chewable tablet is described herein for oral administration of cetirizine dihydrochloride. The formulation is made more palatable by incorporating a combination of a grape flavoring agent with a vanilla flavoring agent. ... | 01/27/2009 |
| 7438927 | Methods of treatment using a gastric retained gabapentin dosage A method of treatment for epilepsy and other disease states is described, which comprises the delivery of gabapentin in a gastric retained dosage form. ... | 10/21/2008 |
| 7435427 | Pharmaceutical semi-solid composition of isotretinoin An oral pharmaceutical composition of isotretinoin containing at least two lipidic excipients, one of them being hydrophilic (i.e. having an HLB value superior or equal to 10), the other being an oily vehicle. ... | 10/14/2008 |
| 7419684 | System and method for manufacturing oral osmotic drug delivery devices, and methods of administering same A system and method for manufacturing oral osmotic drug delivery devices including the use of a mathematical model in deriving relationships between parameters used in manufacturing the devices for a desired release rate of the active drug substance contained therei... | 09/02/2008 |
| 7413751 | Methods of treatment using a gastric retained losartan dosage A method of treatment for hypertension and other disease states is described, which comprises the delivery of losartan in a gastric retained dosage form. ... | 08/19/2008 |
| 7387792 | Pharmaceutical composition for compressed annular tablet with molded triturate tablet for both intraoral and oral administration New pharmaceutical compositions in unit dosage form are disclosed for both intraoral and oral administration to a patient, said unit dosage form configured to be placed intraorally of said patient, which comprises: (a) as a first p... | 06/17/2008 |
| 7384653 | Oral dosage form comprising a therapeutic agent and an adverse-effect agent The present invention provides an oral dosage form comprising a first composition and a second composition. The first composition comprises an effective amount of a therapeutic agent and the second composition comprises an effective amount of an adverse-effect agent... | 06/10/2008 |
| 7351715 | Unit dosage forms for the treatment of herpes simplex The components of this invention are chosen because of their complementarity for the prevention or treatment of diseases caused by the herpes simplex virus. L-Lysine favorably increases the physiologic immunomodulation necessary for defense against this virus. Zinc ... | 04/01/2008 |
| 7338970 | Pharmaceutical composition based on a polymorphic form I of idazoxan Pharmaceutical composition comprising 5 to 20% of an idazoxan salt or of idazoxan hydrate, 10 to 40% of microcrystalline cellulose, 1 to 5% of lubricant, 0.1 to 0.5% of colloidal silica and from 29.5% to 84.8% of lactose, with respect to the total mass. ... | 03/04/2008 |
| 7332183 | Multilayer dosage forms containing NSAIDs and triptans The present invention is directed to multilayer pharmaceutical tablets in which an NSAID and a triptan are present in separate and distinct layers. The layers are in a side-by-side configuration, which allows the dissolution of triptan and NSAID to occur independent... | 02/19/2008 |
| 7329418 | Pharmaceutical tablets having height greater than width An immediate release compressed pharmaceutical tablet that has two or more segments and a top and a bottom and has a height that exceeds the width of the tablet. The height is measured vertically from the top to the bottom of the tablet while it is in the tablet die... | 02/12/2008 |
| 7323192 | Immediate release tablet An immediate release tablet is provided. The tablet comprises at least 60 weight % of an active ingredient and powdered wax having a melting point greater than about 90° C. The tablet may advantageously be produced by direct compression. Although the wax is hydroph... | 01/29/2008 |
| 7318935 | Pharmaceutical tablets with active and inactive segments An immediate release compressed pharmaceutical tablet that has two or more segments and a top and a bottom and has a height that exceeds the width of the tablet. The height is measured vertically from the top to the bottom of the tablet while it is in the tablet die... | 01/15/2008 |
| 7316819 | Oral peptide pharmaceutical dosage form and method of production A pharmaceutical composition for oral delivery of a peptide is in the form of a lamination having at least two layers. The first layer of the lamination includes at least one pharmaceutically acceptable pH-lowering agent. The second layer includes a therapeutically ... | 01/08/2008 |
| 7316821 | Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer A stabilized solid controlled release dosage form having a coating derived from an aqueous dispersion of ethylcellulose is obtained by overcoating a substrate including a therapeutically active with an aqueous dispersion of ethylcellulose and then curing the coated ... | 01/08/2008 |
| 7314641 | High-bioavailability particle coated with fungicide and polymer The present invention discloses a high-bioavailability particle coated with fungicide and polymer, which mainly comprises: (a) a coating layer including fungicide, a polymer, an acidic substance, talc, a bonding agent, ethanol and dichloromethane; (b) an anticoagula... | 01/01/2008 |
| 7314638 | Preparing method for controlled released type tablet tamsulosin HCL and the tablet thereof The present invention relates to a simple and effective method for preparing a tamsulosin HCl sustained-release tablet and a tamsulosin HCl sustained-release tablet produced thereby. The method comprises the steps of: dissolving tamsulosin HCl as an active ingredien... | 01/01/2008 |
| 7303761 | Stabilised pharmaceutical composition comprising an extended release non-steroidal anti-inflammatory agent and an immediate release prostaglandin The present invention is related to a solid pharmaceutical composition comprising two separate regions, a first region comprising at least one non-steroidal anti-inflammatory drug (NSAID) and an adequate pharmaceutical carrier cont... | 12/04/2007 |
| 7300668 | System for manufacturing controlled release dosage forms, such as a zero-order release profile dosage form manufactured by three-dimensional printing The present invention includes controlled release dosage forms and methods of designing and manufacturing dosage forms to obtain specific release profiles, for example, zero-order release profiles, escalating release profiles or decreasing release profiles. The dosa... | 11/27/2007 |
| 7294347 | Coating compositions for bitterness inhibition The present invention discloses coating compositions with taste masking property, comprising a blend of pH sensitive polymers and optionally a pH independent polymer or a blend of the pH sensitive polymer and pH independent polymer used for taste masking of highly b... | 11/13/2007 |
| 7282218 | pH sensitive polymer for inhibiting transformation in drugs The present invention discloses a substantially amorphous pharmaceutical composition comprising a drug that can exist in a variety of polymorphic forms and a pH sensitive polymer, which inhibits the crystallization of the drug during formulation and reconstitution. ... | 10/16/2007 |
| 7282221 | Antiviral product, use and formulation thereof An antiviral product is comprised of at least three dosages forms, each of which has a different release profile, with the Cmax for the antiviral product being reached in less than about twelve hours. In one embodiment, there is an immediate release dosag... | 10/16/2007 |
| 7282225 | Composition and methods for improving retinal health The present invention relates to a nutritional dietary supplement composition comprising a combination of effective amounts of vitamins, minerals, carotenoids, antioxidants, natural herbal extracts in an inert stabilizing carrier, which stabilizes and or enhances vi... | 10/16/2007 |
| 7276252 | Method and form of a drug delivery device, such as encapsulating a toxic core within a non-toxic region in an oral dosage form A drug delivery device such as an oral dosage form (ODF) with a toxic or potent core encapsulated by a non-toxic region. The non-toxic region may be a region including multiple layers, coatings, shells, and combinations thereof, which provides protection to and isol... | 10/02/2007 |
| 7276250 | Sustained release formulations of oxymorphone Sustained release formulations of oxymorphone or pharmaceutically acceptable salts thereof; methods for making the sustained release formulations of oxymorphone or pharmaceutically acceptable salts thereof; and methods for using the sustained release formulations of... | 10/02/2007 |
| 7276253 | Stable drug form for oral administration with benzimidazole derivatives as active ingredient and process for the preparation thereof The invention relates to a stable medicament for oral administration which comprises (a) a core which contains an active ingredient selected from Omeprazole, Lansoprazole and Pantoprazole, together with customary pharmaceutical adjuvants, (... | 10/02/2007 |
