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| Number | Title | Issue Date |
| 8158148 | Pharmaceutical tablets comprising two or more unitary segments Accurate means of dosing with a compressed, segmented pharmaceutical tablet, and tablettes formed from said tablets, is disclosed. ... | 04/17/2012 |
| 7879352 | Scored pharmaceutical tablets comprising a plurality of segments Deeply scored pharmaceutical tablets are disclosed, along with pharmaceutical tablets with a score in a segment that adjoins a segment lacking a pharmacologically effective dose of any drug. ... | 02/01/2011 |
| 7838031 | Method of administering a partial dose using a segmented pharmaceutical tablet A method for providing partial doses of a drug or drugs is disclosed. The method includes breaking of a tablet configured to have an active layer as a first segment and an inactive support layer or substrate as a second segment, or breaking a layered tablet through ... | 11/23/2010 |
| 7780985 | Tablets having a printed separation mark to guide breaking The invention provides a novel “separation marking” on a tablet as a means for assisting in the identification of a region on the tablet that is desired to be able to be broken from time to time. Said breaking allows production of smaller dosage forms known here... | 08/24/2010 |
| 7560122 | Pharmaceutical dosage form bearing pregnancy-friendly indicia A pharmaceutical dosage form comprising at least one active ingredient and destined for administration to pregnant women. The pharmaceutical dosage form bears pregnancy-friendly indicia apt to improve patient compliance with medically recommended dosage regimen resu... | 07/14/2009 |
| 7416738 | Modified release dosage form A modified release dosage form comprising at least one active ingredient and at least two cores surrounded by a shell is provided. The shell comprises at least one opening and provides for modified release of active ingredient upon contacting of the dosage form with... | 08/26/2008 |
| 7363074 | Coatings comprising self-assembled molecular structures and a method of delivering a drug using the same A coating for an implantable medical device is disclosed, the coating including a self-assembled molecular structure. The coating can be used for altering the release rate of a therapeutic substance from the implantable device. ... | 04/22/2008 |
| 7329418 | Pharmaceutical tablets having height greater than width An immediate release compressed pharmaceutical tablet that has two or more segments and a top and a bottom and has a height that exceeds the width of the tablet. The height is measured vertically from the top to the bottom of the tablet while it is in the tablet die... | 02/12/2008 |
| 7318935 | Pharmaceutical tablets with active and inactive segments An immediate release compressed pharmaceutical tablet that has two or more segments and a top and a bottom and has a height that exceeds the width of the tablet. The height is measured vertically from the top to the bottom of the tablet while it is in the tablet die... | 01/15/2008 |
| 7276252 | Method and form of a drug delivery device, such as encapsulating a toxic core within a non-toxic region in an oral dosage form A drug delivery device such as an oral dosage form (ODF) with a toxic or potent core encapsulated by a non-toxic region. The non-toxic region may be a region including multiple layers, coatings, shells, and combinations thereof, which provides protection to and isol... | 10/02/2007 |
| 7270831 | Orally administrable opioid formulations having extended duration of effect Sustained release oral solid dosage forms of opioid analgesics are provided as multiparticulate systems which are bioavailable and which provide effective blood levels of the opioid analgesic for at least about 24 hours. A unit dose of the opioid analgesic contains ... | 09/18/2007 |
| 7214389 | Process A wet granulation process in which a pharmaceutical substance is granulated using a granulating fluid which is a halogenated hydrocarbon which has a normal boiling point below ambient temperature, for example 1,1,1,2-tetraflouroethane, under a pressure sufficient to... | 05/08/2007 |
| 7179799 | (3) and (6) substituted estrogenic compounds Novel estrogenic compounds of Formula I are provided. wherein the bond represented by the wavy line may be a single or double bond such that when the wavy line is a single bond, R1 is selected from the... | 02/20/2007 |
| 7166302 | Complexing agents for compositions containing inclusion complexes The invention provides a composition containing particulate composite of a polymer and a therapeutic agent. The composition also contains a complexing agent. The polymer interacts with the complexing agent in a host-guest or a guest-host interaction to form an inclu... | 01/23/2007 |
| 7108866 | Chronotherapeutic diltiazem formulations and the administration thereof A controlled-release Galenical preparation of pharmaceutically acceptable Diltiazem including the pharmaceutically acceptable salts thereof, suitable for evening dosing every 24 hours containing from about 120 mg to about 540 mg or more (as desired) of the form of D... | 09/19/2006 |
| 7074430 | Controlled release tramadol tramadol formulation A controlled release preparation for oral administration contains tramadol, or a pharmaceutically acceptable salt thereof, as active ingredient. ... | 07/11/2006 |
| 7070968 | DNA damaging agents in combination with tyrosine kinase inhibitors The present invention relates to the signalling pathways connecting DNA damage, such as that induced by ionizing radiation or alkylating agents, and phosphorylation by tyrosine kinases. ... | 07/04/2006 |
| 7067148 | Stabilized pharmaceutical and thyroid hormone compositions and method of preparation A pharmaceutical composition with β-sheet microcrystalline cellulose with improved potency life and methods of preparation therefor. Improved thyroid hormone pharmaceutical compositions comprising 50 weight % or more of β-sheet microcrystalline cellulose. ... | 06/27/2006 |
| 7022344 | Process for producing solid dosage forms A process for producing solid dosage forms by mixing at least one polymer binder, at least one active ingredient and, where appropriate, conventional additives to form a plastic mixture, and shaping, wherein a physiologically tolerated, water-swellable graft copolym... | 04/04/2006 |
| 7008912 | Pressed piece which disintegrates in liquids The invention relates to a pressed piece consisting of ingredients in powder and/or granular form, which contains particles made of a material containing cellulose, particularly in compacted form, which act as an explosive agent. TMP and CTMP can be used as the cell... | 03/07/2006 |
| 6992075 | C(14) estrogenic compounds The present invention relates to novel estrogenic compounds. The present invention also relates to methods of treating estrogen deprivation in a subject comprising administering novel estrogenic compounds. Additionally, the present invention relates to methods of sy... | 01/31/2006 |
| 6962717 | Pharmaceutical compositions A pharmaceutical composition for slow release of active ingredient in the gastrointestinal tract, comprising a plurality of active ingredient-containing particles coated with a material insoluble in gastric and intestinal juices, where the particles have as core a h... | 11/08/2005 |
| 6866865 | Dosage forms and methods for oral delivery of progesterone Oral progesterone unit dosage forms comprising micronized progesterone and a solid polymeric carrier are provided. The dosage forms, upon oral administration, provide a therapeutically effective blood level of progesterone to a subject. The therapeutically effective... | 03/15/2005 |
| 6866863 | Ingestibles possessing intrinsic color change Methods and compositions are provided comprising ingestibles and a thermochromic composition which is informative as to the temperature history of the ingestible, either prior or contemporaneous with use. Various solid or liquid ingestible compositions are provided ... | 03/15/2005 |
| 6855324 | Therapeutic placebo enhancement of commonly-used medications There is provided a method and associated kit for reducing the normal dosage of a pharmaceutical given to a patient for the treatment of a disorder without substantially reducing its effectiveness. During a first predetermined time period, a substantially full dosag... | 02/15/2005 |
| 6767567 | Ingestible elements The invention relates mainly to an element suitable for being ingested, the element including at least one air-passing channel making it possible to avoid choking in the event of being swallowed the wrong way. The present invention applies to the food industry and a... | 07/27/2004 |
| 6692765 | Exactly divisible tablet The invention describes a tablet with two end faces and a circumferential face, in which the mutually opposite end faces of the tablet a) overall are nonplanar and are arranged at least approximately parallel to one another, and b) are each provided wi... | 02/17/2004 |
| 6685962 | Gastroretentive controlled release pharmaceutical dosage forms Pharmaceutical gastroretentive drug delivery systems for the controlled release of an active agent in the gastrointestinal tract are disclosed, which comprise: (a) a single- or multi-layered matrix comprising a polymer that does not retain in the stomach ... | 02/03/2004 |
| 6669957 | Galenic formulations fast disintegrating in the mouth and method for preparing same The invention relates to pharmaceutical dosage forms with rapid disintegration in the mouth and to their process of preparation. These pharmaceutical dosage forms comprise at least one active principle dispersed in a mixture of excipients and are characterized... | 12/30/2003 |
| 6613356 | Weight loss medication and method The invention involves a medication for weight loss by means of appetite suppression and a method for administering this medication to humans and other mammals. The medication comprises potassium butyrate or closely related chemical compounds, together wi... | 09/02/2003 |
| 6607744 | Ingestibles possessing intrinsic color change Methods and compositions are provided comprising ingestibles and a thermochromic composition which is informative as to the temperature history of the ingestible, either prior or contemporaneous with use. Various solid or liquid ingestible compositions ar... | 08/19/2003 |
| 6602521 | Multiplex drug delivery system suitable for oral administration A multiplex drug delivery system suitable for oral administration containing at least two distinct drug dosage packages, which exhibit equivalent dissolution profiles for an active agent when compare to one another and when compared to that of the entire ... | 08/05/2003 |
| 6599531 | Method of making ibuprofen and narcotic analgesic compositions Provided herein are compositions and methods of making compositions of ibuprofen in combination with a narcotic analgesic. Specifically provided is a pharmaceutical tablet composition comprising ibuprofen; a narcotic analgesic; colloidal silicon dioxide; ... | 07/29/2003 |
| 6365183 | Method of fabricating a banded prolonged release active agent dosage form The present invention is directed to an active agent dosage form and methods of its fabrication which is useful for the prolonged delivery of an active agent formulation to a fluid environment of use. The active agent dosage form is a matrix that has on i... | 04/02/2002 |
| 6342248 | Dividable tablet and press-through pack A dividable tablet is not chipped, can be divided easily and accurately, has excellent impact resistance and rarely causes twining in the film-coating step, wherein a dividing line is formed along a center line on the upper surface of the tablet, ridgelin... | 01/29/2002 |
| 6306415 | Natural insect and arthropod repellent A topical insect repellent with extended duration of protection was obtained from mixtures of molecules based on two or more volatile repellent organic molecular species occurring naturally on the human skin surface. The novel repellent comprises mixtures... | 10/23/2001 |
| 6268183 | Method of purifying thuringiensin The invention discloses a two-step process for recovery of thuringiensin, comprising adsorbing the thuringiensin from fermentation broth by calcium silicate, and dissociating the thuringiensin by dibasic sodium phosphate. The resulting thuringiensin can b... | 07/31/2001 |
| 6063404 | Bioadhesive tablet This invention relates to a bioadhesive tablet containing at least one bioadhesive adjuvant and at least one lubricant, with at least one surface of the tablet comprising concentric or parallel, straight and/or curved depressions, and to a method for prod... | 05/16/2000 |
| 6051253 | Production of solid drug forms Solid drug forms are produced by mixing and melting at least one pharmacologically acceptable polymeric binder and at least one pharmaceutical active ingredient, with or without conventional pharmaceutical additives, in the absence of a solvent to give a ... | 04/18/2000 |
| 6020000 | Banded prolonged release active agent dosage form The present invention is directed to an active agent dosage form that is useful for the prolonged delivery of an active agent formulation to a fluid environment of use. The active agent dosage form is a matrix that has an insoluble material circumscribing... | 02/01/2000 |
