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| Number | Title | Issue Date |
| 5091191 | Pharmaceutical composition with improved dissolution property A pharmaceutical composition of the active agent sodium 4-[-hydroxy-5-(1-imidazolyl)-2-methylbenzyl]-3,5-dimethylbenzoate (a thromboxane synthetase inhibitor for treatment of diseases such as thrombosis and asthma) or its optical isomer or its hydr... | 02/25/1992 |
| 5080906 | Method and composition for oral administration of N-acetylcysteine The blood level of orally administered N-acetylcysteine is substantially increased in a mammal when the N-acetylcysteine is administered in combination with tris(hydroxymethyl)aminomethane or a pharmaceutically acceptable salt thereof, in a molar ratio of... | 01/14/1992 |
| 5073377 | Method of preparing oral dosage forms with a granulating composition The invention involves a granulating composition composed of an aqueous solution of magnesium sulfate heptahydrate and sodium hexametaphosphate. This composition can be used to prepare granules of ingredients for inclusion in any formulation for which rap... | 12/17/1991 |
| 5064656 | Uncoated pharmaceutical reaction tablet An uncoated compressed tablet which is used for the preparation of an orally applicable aqueous suspension or solution of a pharmaceutically active substance contains a mixture of the pharmaceutically active substance, a swelling disintegrant and an effer... | 11/12/1991 |
| 5055306 | Sustained-release formulations A granular sustained-release formulation of a pharmacologically active substance presented in the form of a tablet, said tablet comprising sufficient granules to provide a predetermined dose or number of doses of the pharmacologically active substance and... | 10/08/1991 |
| 5055305 | Cleansing compositions Denture cleansing tablet comprising an inorganic persalt bleaching agent, an organic peroxyacid bleach precursor and a solid base material which in the presence of water releases carbon dioxide with effervescence. The composition provides more rapid and e... | 10/08/1991 |
| 5037657 | Effervescent acetysalicylic acid The rate of disintegration and/or dissolution of effervescent acetylsalicylic acid tablets obtained by direct compression of a dry powder mixture is surprisingly increased by incorporating in said mixture powdered dextrose and/or sucrose. Preferably, spra... | 08/06/1991 |
| 5008106 | Method for reducing the microbial content of surfaces with a microbiocidal, anhydrous complex of PVP-H2 O2 What is provided herein is a method for reducing the microbial content of surfaces which comprises contacting said surface with a microbiocidal amount of a substantially anhydrous complex of PVP and H2 O2.... | 04/16/1991 |
| 5004614 | Controlled release device with an impermeable coating having an orifice for release of drug Controlled release devices having a core including an active agent and an outer coating which is substantially impermeable to the entrance of an environmental fluid and substantially impermeable to the release of the active agent during a dispensing perio... | 04/02/1991 |
| 4966776 | Compositions and methods of treating calcium renal stones Methods and compositions useful for the treatment and prophylaxis of calcium renal stones in persons with hypocitraturia or undergoing allopurinol therapy are disclosed. The methods involve administering potassium citrate compositions to persons afflicted... | 10/30/1990 |
| 4965072 | Granulating composition and method The invention involves a granulating composition composed of an aqueous solution of magnesium sulfate heptahydrate and sodium hexametaphosphate. This composition can be used to prepare granules of ingredients for inclusion in any formulation for which rap... | 10/23/1990 |
| 4942039 | Effervescent analgesic antacid composition having reduced sodium content An effervescent analgesic antacid composition having reduced sodium content is produced from a mixture of an analgesic, such as acetylsalicylic acid, acetaminophen, ketoprofen or a mixture thereof, citric acid, sodium bicarbonate, calcium carbonate, potas... | 07/17/1990 |
| 4931278 | Storage-stable preparations of wheat vinasse A storage-stable preparation, containing the ingredients of freshly recovered wheat vinasse, is prepared after optional removal of husks by grinding to colloidal size and drying under mild conditions, whereafter to the product thus obtained optionally are... | 06/05/1990 |
| 4929605 | Pharmaceutical composition for piperidinoalkanol derivatives A pharamaceutical composition in solid unit dosage form comprising (a) a therapeutically effective amount of a piperidinoalkanol compound, or a pharmaceutically acceptable salt thereof, (b) pharmaceutically acceptable nonionic or cationic surfactant in an... | 05/29/1990 |
| 4911930 | Process and means for the heat treatment of powdery or granulate material Solid, loose particulate materials are treated with vaporizable agent in a process chamber. The materials are combined with a mixture of hot gas and vapor in order to condense finely subdivided amounts of the treatment agent on the material. After a suita... | 03/27/1990 |
| 4906474 | Bioerodible polyanhydrides for controlled drug delivery A composition of matter suitable for implantation in the body to effect zero order drug release comprising a drug and a polymer of the formula: ##STR1## wherein R and R' can be the same or different and are hydrophobic organic linkages and n and m ar... | 03/06/1990 |
| 4888177 | Pharamaceutical preparations in the form of instant granules or tablets and process for their manufacture The invention relates to a pharmaceutical preparation that contains at least one pharmaceutically active substance at least one granular carrier material and a layer enveloping the carrier material that contains other components.... | 12/19/1989 |
| 4879105 | Weakly acidic bath agents A weakly acidic bath agent comprising carbon dioxide or a carbon dioxide-generating substance and nicotinic acid or a derivative of nicotinic acid represented by the general formula ##STR1## wherein R represents a group - OR1, in which R | 11/07/1989 |
| 4871549 | Time-controlled explosion systems and processes for preparing the same The invention relates to a Time-Controlled Explosion System in which drug release is caused by explosion of a membrane after a definite time period, said System comprising a preparation in the form of a bead or granule, said preparation comprising a core,... | 10/03/1989 |
| 4867942 | Process for the preparation of an effervescent granular material, effervescent granular material prepared by this process, as well as the use thereof Process for the preparation of an effervescent granular material containing at least one solid, crystalline, edible organic acid, particularly citric acid and at least one alkali metal or alkaline earth metal carbonate splitting off CO2 on reac... | 09/19/1989 |
| 4867977 | Calcium salts A solid stable sugar free and sodium free calcium pharmaceutical composition is disclosed comprising a calcium organic salt, calcium carbonate and an organic polycarboxylic acid.... | 09/19/1989 |
| 4865849 | Tablet for pharmaceutical use able to release active substances at successive times A tablet for pharmaceutical use able to release active substances at successive times, comprising at least; a first layer containing a portion of the active substance with suitable excipients, a barrier layer of polymer material gellable and/or soluble in... | 09/12/1989 |
| 4865842 | Pesticidal composition for water treatment A pesticidal formulation for treatment of water to control water borne pests such as mosquitoes and blackfly or water hyacynth comprises tablets, granules or the like containing in their interior one or more pesticidal ingredients together with one or mor... | 09/12/1989 |
| 4853230 | Pharmaceutical formulations of acid labile substances for oral use Pharmaceutical preparation containing an acid labile compound together with an alkaline reacting compound or an alkaline salt of an acid labile compound optionally together with an alkaline compound as the core material, one or more subcoating layers comp... | 08/01/1989 |
| 4844905 | Granule remaining in stomach A granule of drug to remain in the stomach comprises a core comprising a pharmaceutically effective ingredient, a foaming layer coated on said core and an expansive film coated on said layer.... | 07/04/1989 |
| 4832956 | Disintegrating tablet and process for its preparation A desintegration tablet contains the filler material in a form and/or size which when coming in contact with water at ambient temperature dissolves so slowly that the water absorption and the action of the desintegration agent are not affected. The grains... | 05/23/1989 |
| 4812315 | Diet pills A diet pill in the form of a sealed container of cellulose material containing a gas producing powder, such as sodium bicarbonate which expands the pill in volume as the result of reaction with gastric juice and liquid in the user's stomach. Such expansio... | 03/14/1989 |
| 4806358 | Therapeutic compositions Novel pharmaceutical powder and tablet compositions comprise ibuprofen or a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable effervescent couple that produces carbon dioxide in the presence of water, a pharmaceutically acceptable su... | 02/21/1989 |
| 4783331 | Method for solubilization of aspartame in effervescent aqueous systems; and composition A method and composition for providing aspartame as a sweetener in effervescent calcium ion-generating systems is provided. The method includes a step for providing a selected surfactant in association with the aspartame sweetener, to provide for aqueous ... | 11/08/1988 |
| 4716046 | Pulverulent water-soluble nonhygroscopic composition for preparing beverages with a lasting effervescence and method for preparing the same A nonhygroscopic pulverulent composition for preparing beverages with a lasting effervescence comprises a first component or group of components mixed with a second component or group of components capable of reacting mutually in the presence of water to ... | 12/29/1987 |
| 4704269 | Effervescent antacid and analgesic compositions Disclosed are water soluble effervescent antacid, analgesic powder and tablet formulations which in a preferred embodiment are sodium, sucrose and aspirin free. The formulation is administered through the ingestion of an aqueous solution of the powder or ... | 11/03/1987 |
| 4678661 | Effervescent composition and method of making same Effervescent granulates, particularly for the manufacture of effervescent tablets, comprising at least one solid, crystalline edible organic acid and at least one carbonate which releases carbon dioxide upon reaction with the organic acid, the acid crysta... | 07/07/1987 |
| 4675174 | Veterinary dispenser delivering beneficial agent by gas power generated in situ A dispensing system is disclosed for delivering a beneficial agent. The dispensing system comprises (1) a housing defining an internal space, (2) a gas-generating composition in the space, (3) a dense member in the space, (4) a composition comprising a be... | 06/23/1987 |
| 4650669 | Method to make effervescent calcium tablets and calcium tablets produced thereby Described is a directly compressible formulation comprising calcium carbonate, citric acid, and a compression vehicle. In the preferred embodiment, the compression vehicle comprises a maltodextrin and lactose. The formulation can be compressed into an eff... | 03/17/1987 |
| 4592855 | Effervescent compositions Effervescent compositions are provided having an effervescent and cleansing action. The effervescent compositions are formed from an essentially anhydrous base medium and an inorganic oxide material containing an adsorbed gas. Upon contact of the composit... | 06/03/1986 |
| 4414198 | Rapidly disintegrable tablet composition and method Rapidly water-disintegrable tablet is provided comprising an active ingredient such as a foodstuff or medicament, and distributed therewithin a small but effective amount of a tablet disintegrable system comprising an unreacted, intimate mixture of algini... | 11/08/1983 |
| 4344929 | Method of delivering drug with aid of effervescent activity generated in environment of use A method is disclosed for delivering a drug substantially-free of rapid precipitation from an osmotic device. The osmotic device comprises a semipermeable wall surrounding a compartment housing (1) a drug that exhibits limited solubility under neutral and... | 08/17/1982 |
| 4317743 | Process for making microcapsules and resulting product Oil-containing microcapsules are produced by emulsifying an oily solution of isocyanatoamidine products into an aqueous solution of emulsifier to form oil-in-water emulsion. The reactive isocyanatoamidine products are subsequently hydrolyzed into an imper... | 03/02/1982 |
| 4309213 | Process of encapsulation by interfacial polycondensation The process for the encapsulation of a liquid hydrophobic substance involves, in a first stage, dispersing an organic phase containing the liquid hydrophobic substance to be encapsulated and at least one polyfunctional hydrophobic monomer having functiona... | 01/05/1982 |
| 4303548 | Process for coating dispersed minute droplets with membrane Microcapsules containing water-insoluble liquid, of which wall membrane is urea-formaldehyde resin is produced by the addition of a water soluble organic acid, urea and formaldehyde to an emulsion of the liquid, which is made by a nonionic emulsifier and ... | 12/01/1981 |
