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| Number | Title | Issue Date |
| 8187631 | Direct compression polymer tablet core The present invention provides a tablet core which comprises at least about 95% by weight of an aliphatic amine polymer. The invention also provides a method of producing a tablet core comprising at least about 95% by weight of an aliphatic amine polymer resin The m... | 05/29/2012 |
| 8182837 | Methods and compositions for reducing the risk associated with the administration of opioid analgesics in patients with diagnosed or undiagnosed respiratory illness The present invention relates to methods for reducing the risk associated with the administration of opioid analgesics in patients diagnosed or undiagnosed with respiratory illness by administering an analgesic composition comprising a sub-analgesic dosage of a p-op... | 05/22/2012 |
| 8173161 | Method of administering a pharmaceutical active ingredient A method for reducing the friability of soft substrates by applying an effective amount of a water soluble, polymeric dispersion to at least a portion of a treatment surface of the substrate, such that less than about 90% of the exterior surface has the dispersion a... | 05/08/2012 |
| 8168220 | Dosage forms of active ingredients containing hydroxystilbene for treating menopausal complaints The invention relates to novel dosage forms containing hydroxystilbene, to a method for producing said dosage forms and to their use for treating female menopausal complaints, juvenile oligomenorrhoea and dysmenorrhoea, primary and secondary amenorrhoea or endometri... | 05/01/2012 |
| 8168218 | Delayed release tablet with defined core geometry A press-coated tablet comprising a core containing an drug substance, and a coating, the core being disposed within the coating such that the coating has a first thickness about an axis A-B and a thickness about an orthogonal axis X-Y, such that the coating about th... | 05/01/2012 |
| 8168221 | Composition 064 A pharmaceutical composition which comprises N-(3-methoxy-5-methylpyrazin-2-yl)-2-(4-[1,3,4-oxadiazol-2-yl]phenyl)pyridine-3-sulphonamide with mannitol and/or 5 microcrystalline cellulose is described. ... | 05/01/2012 |
| 8168219 | Synergistic binder composition, method for making same, and tablets of an active and said binder having advantageous hardness and friability Tablets of a pharmaceutical, nutritional or vitamin active compound or composition, e.g. a poorly compressible drug are made by direct compression using a synergistic binder composition of co-processed (a) copolymer of vinylpyrrolidone (VP) and vinyl acetate (VA) an... | 05/01/2012 |
| 8158147 | Modified release formulations of at least one form of tramadol The present invention relates to a modified release composition of at least one form of tramadol which is a delayed and extended release composition for oral administration suitable for once daily dosing. That composition comprises a core comprising at least one for... | 04/17/2012 |
| 8158146 | Stable combinations of amlodipine besylate and benazepril hydrochloride The present invention provides a pharmaceutical composition comprising benazepril and amlodipine wherein the benazepril and the amlodipine are in physical contact with one another, and methods for making the same. ... | 04/17/2012 |
| 8147871 | Pharmaceutical formulations The present invention is directed to novel pharmaceutically acceptable polymeric compositions suitable for melt extrusion and injection molding of single or multi-component pharmaceutical dosage forms comprising a plurality of drug substance containing sub-units, be... | 04/03/2012 |
| 8128957 | Modified release compositions of at least one form of tramadol The present invention relates to a modified release composition of at least one form of tramadol which is a delayed and extended release composition for oral administration suitable for once daily dosing. That composition comprises a core comprising at least one for... | 03/06/2012 |
| 8124124 | Compressed tablet formulation comprising non-steroidal anti-inflammatory drugs and methods A compressed tablet composition comprising: a granular component comprising a plurality of solidified melt granules of a non-steroidal anti-inflammatory drug (NSAID) having a melting point in the range 30-300° C. and incorporating a disintegrant uniformly dispersed... | 02/28/2012 |
| 8124125 | Solid dosage form comprising a fibrate The invention provides stable, solid dosage forms and pharmaceutical compositions in particulate form comprising a fibrate, for example fenofibrate, dissolved in an non-aqueous vehicle in order to ensure improved bioavailability of the active ingredient upon oral ad... | 02/28/2012 |
| 8119158 | Effervescent oral fentanyl dosage form and methods of administering fentanyl Fentanyl-containing dosage forms and methods using same are described. These dosage forms include substantially less fentanyl by weight than known oral formulation and have advantages in terms of reduced cost and reduced side effects. These dosage forms are intended... | 02/21/2012 |
| 8092831 | Antihistamine and decongestant system The present invention relates to an oral pharmaceutical formulation that employs: (1) a compressed core containing a decongestant or pharmaceutically acceptable salt thereof; (2) a delayed release coating on the compressed core and (3) immediate release therapeutic ... | 01/10/2012 |
| 8092832 | Generally linear effervescent oral fentanyl dosage form and methods of administering Fentanyl containing dosage forms and methods using same are described. These dosage forms include substantially less fentanyl by weight than know oral formulation and have advantages in terms of cost and side effects. These dosage forms are intended for oral adminis... | 01/10/2012 |
| 8071128 | Intrabuccally rapidly disintegrating tablet and a production method of the tablets An intrabuccally rapidly disintegrating tablet which is manufactured by a simple method, has an enough practical hardness and is rapidly disintegrated in the buccal cavity and its production method. The intrabuccally rapidly disintegrating tablet is produced by grow... | 12/06/2011 |
| 8062664 | Process for preparing formulations of lipid-regulating drugs A process for preparing a formulation of a lipid-regulating drug is disclosed, the process comprising dissolving lipid-regulating drug in a solvent free of surfactant to form a solution, premixing an excipient to form an admixture, wet granulating the solution and a... | 11/22/2011 |
| 8057820 | Enteric coated aspirin granules comingled with binder The invention relates to a tablet capable of being chewed or disintegrated in the oral cavity, which comprises an enteric coated granule comprising an intimate mixture of an aspirin active ingredient and at least one binder capable of preferentially absorbing ambien... | 11/15/2011 |
| 8039019 | Pharmaceutical formulation containing a biguanide and an angiotensin antagonist A pharmaceutical dosage form comprising a controlled release component comprising an antihyperglycemic drug in combination with a second component comprising a angiotensin antagonist is herein disclosed and described. ... | 10/18/2011 |
| 8034380 | Immediate release pharmaceutical tablets with height greater than width An immediate release compressed pharmaceutical tablet that has two or more segments and a top and a bottom and has a height that exceeds the width of the tablet. The height is measured vertically from the top to the bottom of the tablet while it is in the tablet die... | 10/11/2011 |
| 8034379 | Ion-strength independent sustained release pharmaceutical formulation The present invention is related to an optionally coated pharmaceutical hydrophilic gel forming matrix formulation comprising one or more active substances and having a prolonged release of said one or more active substances upon exposure to gastrointestinal fluids,... | 10/11/2011 |
| 8029823 | Controlled release and taste masking oral pharmaceutical composition Controlled release and taste masking compositions containing one or more active principles inglobated in a three-component matrix structure, i.e. a structure formed by successive amphiphilic, lipophilic or inert matrices and finally inglobated or dispersed in hydrop... | 10/04/2011 |
| 8026211 | Methods and formulations for increasing intestinal function A method for increasing intestinal function is provided. The method comprising orally and/or enterally administering to a subject in need thereof a therapeutically effective amount of insulin, thereby increasing intestinal function. ... | 09/27/2011 |
| 8007824 | Galenic formulations of organic compounds The present invention relates to a solid oral dosage form comprising a therapeutically effective amount of aliskiren, or a pharmaceutically acceptable salt thereof, and wherein the active ingredient is present in an amount of more than 46% by weight based on the tot... | 08/30/2011 |
| 8007825 | Oral compositions containing a salivation inducing agent Oral dosage forms, and particles used therein, containing salivation inducing agents are disclosed. The salivation agents may be in the core of the dosage form and/or in coatings applied thereto, or alternatively may be within particles and/or the matrix of such dos... | 08/30/2011 |
| 8003126 | Stable tablet formulation The present invention is directed to a stable solid formulations of tetrahydrobiopterin, processes for producing them, and treatment methods using such formulations. ... | 08/23/2011 |
| 7993673 | Swallow tablet comprising paracetamol A dosage form such as a swallow tablet or a capsule formulation is described comprising paracetamol, low levels of sodium bicarbonate or potassium bicarbonate or mixtures thereof, and at least one pharmaceutically acceptable excipient. ... | 08/09/2011 |
| 7988996 | Pharmaceutical tablets with height greater than width Described is a compressed multiple layer pharmaceutical tablet that has a height that exceeds the width of the tablet. The height is measured vertically from the top to the bottom of the tablet while it is in the tablet die in which it is fully compressed, after com... | 08/02/2011 |
| 7985418 | Aliphatic amine polymer salts for tableting The tablets, compositions and methods of the present invention, comprising a carbonate salt of an aliphatic amine polymer and s monovalent anion can prevent or ameliorate acidosis, in particular acidosis in patients with renal disease. The tablets and compositions o... | 07/26/2011 |
| 7985419 | Divisible tablet and associated methods A divisible pharmaceutical tablet comprises an upper portion and a lower portion, the upper portion including at least one upper convex surface bordering at least one dividing notch. A ridgeline is formed between the at least one dividing notch and the at least one ... | 07/26/2011 |
| 7981443 | Method of treating sleep disordered breathing using topiramate A method for treating snoring, sleep apnoea and other forms of sleep disordered breathing involves administration to a patient of a therapeutically effective amount of topiramate over an appropriate period of time, such as a period substantially coinciding with the ... | 07/19/2011 |
| 7972621 | Process for formulating fast dispersing dosage forms comprising at least one fish gelatin selected on the basis of molecular weight The invention disclosed herein relates to a pharmaceutical composition comprising a carrier and an active ingredient, wherein the carrier is at least one fish gelatin predetermined on the basis of the molecular weight profile of the gelatin. In some embodiments, par... | 07/05/2011 |
| 7968119 | Tamper-proof narcotic delivery system A composition for oral, transdermal or subdermal administration to a subject is described. The composition contains: (a) an agonist component; (b) an antagonist component containing at least one antagonist and having a delayed time of release; and (c) an immediate r... | 06/28/2011 |
| 7955620 | Stable oral composition The present invention provides a stable oral composition comprising a therapeutically effective amount of desloratadine and a stabilizer selected from the group comprising an antioxidant, a pharmaceutically acceptable organic compound that provides an alkaline pH, a... | 06/07/2011 |
| 7951398 | Pharmaceutical preparation comprising an active dispersed on a matrix The present invention relates to the field of pharmaceutical technology and describes a novel advantageous preparation for an active ingredient. The novel preparation is suitable for producing a large number of pharmaceutical dosage forms. In the new preparation, an... | 05/31/2011 |
| 7951397 | Oral dosage form containing a PDE 4 inhibitor as an active ingredient and polyvinylpyrrolidon as excipient Dosage forms for oral administration of a PDE 4 inhibitor whose solubility is slight are described. They contain PVP as binder. ... | 05/31/2011 |
| 7943171 | Use of branched malto-dextrins as granulation binders A method for preparing granules of active substances containing food fibers which consists in granulating the active substances mixed with branched malto-dextrins having between 15 and 35% of 1-6 glucoside bonds, a reducing sugar content less than 20%, a polymolecul... | 05/17/2011 |
| 7943169 | Absorbable solid compositions for topical treatment of oral mucosal disorders The invention provides a solid, self-bioadhesive composition for topical application that adheres to the oral mucosal tissue comprising a therapeutically effective amount of at least one herbal or homeopathic active agent; and a pharmaceutically acceptable solid bio... | 05/17/2011 |
| 7943170 | Sustained release paracetamol containing compositions A pharmaceutical composition comprising an immediate release phase and a sustained release phase of paracetamol is described which has a unique in vitro dissolution profile resulting in advantageous pharmacokinetic properties. ... | 05/17/2011 |
