Did You Know...
...that the Slinky toy was the result of a failed attempt by engineer Richard James to produce an antivibration device for ship instruments? His goal was to develop a spring that would instantaneously counterbalance the wave motion that rocks a ship at sea. Instead, he developed the Slinky.
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| Number | Title | Issue Date |
| 5093130 | Powder coated hydrogel capsules Methods and materials are provided for coating hydrogel capsules containing botanic tissue with an inert substance that decrease capsule surface adhesiveness and facilitates singulation and flowability of the hydrogel capsules. The coating may be composed... | 03/03/1992 |
| 5077052 | Chitosan derivatives useful in compositions for coating feedstuff additives intended for ruminants Novel organosoluble derivatives of chitosan, useful in coating biologically active feedstuff additives intended for ruminants, to provide coatings which are stable at a pH greater than 5 and which release the biologically active substance at a pH below 3.... | 12/31/1991 |
| 5064656 | Uncoated pharmaceutical reaction tablet An uncoated compressed tablet which is used for the preparation of an orally applicable aqueous suspension or solution of a pharmaceutically active substance contains a mixture of the pharmaceutically active substance, a swelling disintegrant and an effer... | 11/12/1991 |
| 5064650 | Controlled-release salt sensitive capsule for oral use and adhesive system A salt sensitive capsule has been developed which dissolves in the mouth and releases the encapsulated internal ingredient(s). The outer salt sensitive shell maintains its integrity when kept at a preselected aqueous salt concentrations. When introduced i... | 11/12/1991 |
| 5057322 | Method of treating mast cell disease A method of treating a patient suffering from mast cell disease comprising daily administration to such patient of from about 1 to about 150 mg of a pure narcotic antagonist, e.g., nalmefene or naltrexone. The antagonist may be administered in divided dos... | 10/15/1991 |
| 5032405 | Oral pharmaceutical composition for acid sensitive proteinaceous agents An orally administrable formulation of a biologically active, acid sensitive, proteinaceous agent comprises a composition of a lyophilized mixture of the proteinaceous agent and maltose, optionally with a particulate diluent. This composition is then unif... | 07/16/1991 |
| 5030452 | Dispensing devices powered by lyotropic liquid crystals This invention relates to devices useful for the controlled delivery of one or more beneficial agents to an environment of use. More specifically, this invention concerns such devices which are powered by lyotropic liquid crystals. This inventioin also re... | 07/09/1991 |
| 5023083 | Azarbine composition A method for treating azaribine-responsive diseases in patient's who exhibit severe pyridoxal phosphate depletion following the oral administration of azaribine comprises first encapsulating azaribine in a film-forming substance which is selectively solub... | 06/11/1991 |
| 5015479 | Sustained release capsule or tablet formulation comprising a pharmaceutically acceptable dihydropyridine A sustained release capsule or tablet formulation suitable for once-daily administration comprises an adsorbate of a mixture of a pharmaceutically useful dihydropyridine and a polyvinylpyrrolidone having an average-molecular weight greater than 55,000 ads... | 05/14/1991 |
| 5004612 | Pharmaceutical compositions comprising esters or amides as active ingredients The present invention relates to new pharmaceutical compositions characterizing that esters or amides are suspended or dissolved in a middle chain glyceride or a mixture thereof. These pharmaceutical compositions inhibit the degradation of the active ingr... | 04/02/1991 |
| 4981695 | Composition comprising L-dopa The present invention relates to a multiple-unit-dose comprising L-dopa as pharmaceutically active compound, whereby the composition provides a release of L-dopa in accordance with a test in accordance with U.S. Pharmacopeia Standards in an artificial gas... | 01/01/1991 |
| 4965089 | Method and apparatus for the gelatin coating of caplets A caplet dipping machine includes a caplet holding plate including sets of caplet gripping collets on both sides thereof so that caplets can be dipped on one end, pushed through the plate and dipped at the other end. The collets on one side are mounted ba... | 10/23/1990 |
| 4925678 | Endothelial envelopment drug carriers This application describes the preparation and in vivo testing of surface coatings and matrix materials, which when applied to or caused to comprise the carriers for drugs and diagnostic agents, and administered in a fashion that allows efficient vascular... | 05/15/1990 |
| 4910021 | Targeted enternal delivery system A capsule for oral administration of a pharmaceutically active ingredient contains a pharmaceutical composition comprising the active ingredient, for example, a peptide, an absorption promoter and usually, a carrier. The absorption promoter is capable of ... | 03/20/1990 |
| 4889723 | Pharmaceutical compositions comprising esters or amides as active ingredients The present invention relates to new pharmaceutical compositions characterizing that esters or amides are suspended or dissolved in a middle chain glyceride or a mixure thereof. These pharmaceutical compositions inhibit the degradation of the active ingre... | 12/26/1989 |
| 4849227 | Pharmaceutical compositions A composition adapted to administer a pharmocologically effective amount of a pharmaceutical agent when ingested orally comprising (a) a pharmaceutical agent; (b) a lipid coating materials; and (c) an enteric coating materials optionally comprising water ... | 07/18/1989 |
| 4834983 | Pharmaceutical compositions Pharmaceutical compositions containing an iron complex of 3-hydroxy-4-pyrone or of a 3-hydroxy-4-pyrone in which one or more of the hydrogen atoms attached to ring carbon atoms are replaced by an aliphatic hydrocarbon group of 1 to 6 carbon atoms, are of ... | 05/30/1989 |
| 4834981 | Dietary vaccine for inhibiting metabolism of methanol Apparatus and a method for inhibiting the metabolism of methanol in a human. The apparatus comprises carrier means for a source of ethanol. The carrier means, when combined with a source of ethanol and introduced in the digestive tract of a human being, p... | 05/30/1989 |
| 4832686 | Method for administering interleukin-2 A biocompatible, biodegradable, bioerodible composite polymer matrix comprising interleukin-2 in an appropriate polymer. The polymer may be a polymer or copolymer of lactic acid, lactide, glycolide, glutamic acid, or it may be collagen or albumin. The mat... | 05/23/1989 |
| 4820524 | Gelatin coated caplets and process for making same A novel capsule-like medicament, method for producing such medicaments and apparatus are disclosed. The method provides a procedure for coating solid cores, such as caplets, with gelatinous coatings to produce a shiny, capsule-like medicament. Such medica... | 04/11/1989 |
| 4816259 | Process for coating gelatin capsules This invention provides a new gelatin capsule formulation and subcoating for producing soft gelatine capsules having better mechanical strength and an improved capacity for adhering to known coating compositions, particularly enteric coating compositions.... | 03/28/1989 |
| 4816260 | Personal protection device A personal protection device having a flexible support, and a breakable capsule at a front surface of the support, which capsule contains skunk essence. Upon attack, the user bends the support to break the capsule in the direction of an assailant in order... | 03/28/1989 |
| 4800056 | Process for making dispenser with cooperating elements A method of forming a dispenser for delivering a beneficial agent to a biological environment. A beneficial agent and an expandable composition are placed in a capsule made of fluid dissolvable material. The capsule is closed and surrounded by a semiperme... | 01/24/1989 |
| 4794000 | Coacervate-based oral delivery system for medically useful compositions The present invention provides for an oral drug delivery system based on a two phase liquid coacervate system prepared from water and one or more surfactants selected from anionic, cationic, amphoteric, and non-toxic surfactants, polysaccharides, syntheti... | 12/27/1988 |
| 4670287 | Method of film-coating hard capsules A method of film-coating hard capsules is provided which comprises subjecting, drug-filled hard capsules to a vacuum to remove air entrapped therein and then coating the evacuated capsules while under a vacuum with a film-forming substance which is select... | 06/02/1987 |
| 4456628 | Process for film-coating a particulate solid, and emulsions for conducting the process A process of coating a particulate medicinal agent; comprising the application to said medicinal agent of a liquid composition containing a water-insoluble film-forming agent, a lipophilic solvent, a hydrophilic solvent and water, said liquid composition ... | 06/26/1984 |
| 4452862 | Pharmaceutical coating materials soluble or swellable in gastric juice and pharmaceutical dosage forms coated therewith Coating materials for pharmaceutical dosage forms contain, besides the conventional liquid or solid additives for pharmaceutical coatings, a binder comprising a synthetic polymer, prepared by emulsion polymerization, having 5 to 100% by weight of units de... | 06/05/1984 |
| 4339463 | Enterosoluble hard-capsulated medicaments The invention provides a novel means for overcoming the problem of undue and irregular delay in the exhibition of the effect of medicine when a patient is administrated with an enterosoluble hard-capsulated medicament. The unexpected discovery that the ke... | 07/13/1982 |
| 4017647 | Method for providing enteric coatings on solid dosage forms Enteric coatings are provided on solid pharmaceutical dosage forms by a method comprising covering the dosage froms with an aqueous solution of a polymeric substance having carboxyl groups in the watersoluble salt form and contacting the thus coated dosag... | 04/12/1977 |
| 3959540 | Gastric juice resistant gelatin capsules and a process for the production thereof Gastric juice resistant gelatin capsules characterized by a gastric juice resistant outer coating of an anionic polymerizate of methacrylic acid and acrylic acid esters and an intermediate layer between the outer layer and the gelatin shell of a cationic ... | 05/25/1976 |
