Did You Know...
...that when IBM conducted a market study of Chester Carlson's invention in 1959, the company concluded that it would take only 5000 units of his new product to saturate the market? IBM therefore declined to be part of the new product introduction. Too bad for IBM. Carlson's invention was the xerography process, and his new product was the beginning of the Xerox Corporation. It is estimated that every day, worldwide, 3,000,000,000 copies are made!!
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| Number | Title | Issue Date |
| 5532002 | Gelatin pharmaceutical formulations Hard gelatin capsules contain: (a) a fat-soluble nutrient, such as a fat-soluble vitamin (A, D, E or K) or an unsaturated fatty acid glyceride; (b) a nonionic surfactant, such as a polyoxyethylated (optionally hydrogenated) castor oil, and/or a polyethyle... | 07/02/1996 |
| 5527543 | Pharmaceutical granulate Disclosed is a process of preparing granules involving first preparing a carrier comprising diluent, binder, and optionally a disintegrating agent. In a container separate from said carrier, a steroid, lubricant and, optionally, an antioxidant are dissolv... | 06/18/1996 |
| 5525354 | Pharmaceutical preparation and process for its manufacture In a pharmaceutical preparation for oral use containing a pharmacologically acceptable salt of a bisphosphonic acid, the improvement comprising: a drug delivery form of the preparation which is enteric coated with a film which dissolves at a pH-value of f... | 06/11/1996 |
| 5525634 | Colonic drug delivery system A colonic delivery system for delivering a drug to the colon is provided. The system comprises a drug in combination with a matrix, wherein the matrix comprises a saccharide-containing polymer. According to the invention, the matrix is resistant to chemic... | 06/11/1996 |
| 5516531 | Spherical granules having core and their production The spherical granules having a core coated with spraying powder containing a drug and low substituted hydroxypropylcellulose, because of their excellent hardness, can be coated further evenly, (e.g. sustained release coating, gastric coating, enteric coa... | 05/14/1996 |
| 5512302 | Pharmaceutical process using starch A process for the preparation of a pharmaceutical composition in the form of agglomerates comprising 70-97% by weight of 2-(4-isobutylphenyl)propionic acid or a pharmaceutically acceptable salt thereof and 3-30% by weight of a starch component, said proce... | 04/30/1996 |
| 5510114 | Slow release pharmaceutical composition containing a bile acid as an active ingredient A slow-release pharmaceutical composition containing a bile acid as active ingredient and comprising at least one bioadhesive substance and at least one high specific gravity substance, an aliquot thereof being enteric coated and the remainder being non-e... | 04/23/1996 |
| 5508276 | Duloxetine enteric pellets A superior enteric formulation of the antidepressant drug, duloxetine, is in the form of enteric pellets of which the enteric layer comprises hydroxypropylmethylcellulose acetate succinate.... | 04/16/1996 |
| 5498422 | Sustained release capsule A sustained release capsule excellent in adhesion characteristics in the gastrointestinal tract, stability and so on is provided. The capsule is characterized in that a polymer excellent in initial adhesion and a polymer excellent in shape-retaining abili... | 03/12/1996 |
| 5489439 | Granular pharmaceutical formulations A process for the preparation of a granule comprising a pharmaceutical which process comprises contacting a particulate, spray-dried substrate and a particulate pharmaceutical to obtain a particle comprising a substrate core carrying an adsorbed pharmaceu... | 02/06/1996 |
| 5474786 | Multilayered controlled release pharmaceutical dosage form This invention is directed to a multilayered controlled release pharmaceutical dosage form. More particularly the dosage form is adapted for water soluble drugs and comprises a plurality of coated particles wherein each has multiple layers about a core co... | 12/12/1995 |
| 5472708 | Pulsatile particles drug delivery system Unit dosage form for delivering drugs into the body in a series of sequential, pulsatile releasing events employs conventional pharmaceutical equipment and processes for optimum economy, reliability, and bioavailability. The system can be used with drugs ... | 12/05/1995 |
| 5464632 | Rapidly disintegratable multiparticular tablet Rapidly disintegratable multiparticulate tablet the excipient mixture of which is suitable for imparting a disintegration rate such that the tablet disintegrates in the mouth in an extremely short time, notably in less than sixty seconds, characterized by... | 11/07/1995 |
| 5458888 | Controlled release tablet formulation The present invention provides a controlled release dosage form which may be made using a blend having an internal drug containing phase and an external phase which comprises a polyethylene glycol polymer which has a weight average molecular weight of fro... | 10/17/1995 |
| 5453280 | Production of pellets composed of an ephedrine derivative A process for producing pellets which are markedly spherical and have a particle size in the range from 0.1 to 4 mm and an apparent density above 0.5 g/cm3, and which are composed of 90-100% by weight of an ephedrine derivative and 0-10% by wei... | 09/26/1995 |
| 5453282 | Dietary lipid digestion-absorption inhibitory agents and ingesta Disclosed herein are dietary lipid digestion-absorption inhibitory agents and ingesta, comprising as an active ingredient a mixture of chitosan and ascorbic acid or a salt thereof. Also disclosed is a therapeutic method for obesity, which comprises admini... | 09/26/1995 |
| 5445829 | Extended release pharmaceutical formulations An extended release pharmaceutical formulation adapted to approach zero order release of drug over a 12 to at least 24 hour period, comprised of a mixture of 0 to about 50% of an immediate release particle containing a drug, inert substrate and binder, co... | 08/29/1995 |
| 5445828 | Programmed release oral solid pharmaceutical dosage form A programmed release pharmaceutical dosage form comprising a core, containing the active ingredient, coated by a hydrophobic layer is described. Such dosage forms release the active ingredient after a pre-established no-release interval which does not dep... | 08/29/1995 |
| 5437873 | Superior tasting pharmaceutical composition having porous particles and the process of preparing such pharmaceutical composition The present invention is directed towards a process for producing a superior tasting pharmaceutical composition having porous granules produced through in situ gas generation using effervescence-producing ingredients. The method disclosed herein is especi... | 08/01/1995 |
| 5430021 | Hydrophobic drug delivery systems A pharmaceutical preparation including a drug incorporated into hydrophobic particles comprised of long chain carboxylic acid or ester thereof or long chain alcohol, wherein the particles are incorporated into a unit dosage form and are individually coate... | 07/04/1995 |
| 5417985 | Solid and porous single dosage form comprising particles in the form of beads and its preparation This invention relates to new solid and porous single dosage form comprising beads and its preparation. This new solid single dosage form applies to the administration of therapeutically active substances, nutrition agents, diagnostic agents or cosmetic a... | 05/23/1995 |
| 5413777 | Pulsatile once-a-day delivery systems for minocycline Pharmaceutical delivery systems containing 7-dimethyl-6-deoxy-6-demethyltetracycline or a non-toxic acid addition salt thereof comprising mixtures or separate administration units of pH sensitive polymer coated spherical granules adapted to release the ... | 05/09/1995 |
| 5409711 | Pharmaceutical formulations The taste of orally administered drugs is masked by coating the drug with a polymeric membrane which is soluble only at a pH of 5 or more. An acid substance is included in the formulation containing the coated drug to reduce or prevent the dissolution of ... | 04/25/1995 |
| 5405621 | Compositions of gastric acid-resistant microspheres containing buffered bile acids Disclosed are gastric acid-resistant polymer-coated buffered-bile acid compositions, process for their preparations and methods of treating digestive disorders, impaired liver function, autoimmune diseases of the liver and biliary tract, preventing colon ... | 04/11/1995 |
| 5401512 | Delayed release oral dosage forms for treatment of intestinal disorders An orally administrable pharmaceutical dosage form for selectively administering a drug to the intestine comprises a plurality of enteric coated granules of the drug contained in an enterically coated capsule which releases the granules in the small intes... | 03/28/1995 |
| 5399357 | Sustained release preparations There is provided a matrix preparation produced by dispersing a pharmaceutically active ingredient into a matrix which is solid at ambient temperature and comprised of a fatty acid ester of a polyglycerol. The preparation has stable release controlling ab... | 03/21/1995 |
| 5397574 | Controlled release potassium dosage form A pharmaceutical composition for oral administration of potassium salt in a form not irritating to the gastrointestinal mucosa comprises tablets or capsules of micropellets of a potassium salt, such as potassium chloride. The micropellets are coated with ... | 03/14/1995 |
| 5395626 | Multilayered controlled release pharmaceutical dosage form This invention is directed to a multilayered controlled release pharmaceutical dosage form. More particularly the dosage form is adapted for water soluble drugs and comprises a plurality of coated particles wherein each has multiple layers about a core co... | 03/07/1995 |
| 5393533 | Pharmaceuticals microencapsulated by vapor deposited polymers and method A microencapsulated pharmaceutical is formed by vapor depositing a polymeric film about an active pharmaceutical agent. The film thickness of the vapor deposited film is controlled to provide effective controlled release of said pharmaceutical agent subse... | 02/28/1995 |
| 5380533 | Gastroresistant pharmaceutical formulations for oral administration containing bile acids Pharmaceutical formulations for oral administration coated by an enterosoluble gastroresistant film, preferably selected from gastroresistant granulates, gastroresistant tablets, gastroresistant hard gelatine capsules containing powders or granulates or t... | 01/10/1995 |
| 5380532 | Process for the preparation of medication in the form of pearls Process for the preparation of pearls based on a pharmaceutical active substance exhibiting an indefinite crystallization point. The said active substance is mixed in molten form with a pharmaceutical excipient promoting the solidification of the active substa... | 01/10/1995 |
| 5376385 | Releasably bound active materials A process for binding water-sensitive active materials in essentially non-aqueous systems.... | 12/27/1994 |
| 5374430 | Pharmaceutical formulation The residence time in the human stomach of a pharmaceutical, gastric controlled release unit can be increased significantly if the units has a density that is much higher than normal. A preferred oral dosage form according to the invention comprises table... | 12/20/1994 |
| 5370879 | Formulations and their use in the treatment of neurological diseases Pharmaceutical formulations comprise a mono- or di-aminopyridine active agent for administration on a once- or twice-daily basis for use in the treatment of neurological diseases, in particular multiple sclerosis and Alzheimer's disease. The formulations,... | 12/06/1994 |
| 5368861 | Gastric preparation with sustained release A gastric preparation developed in order to solve the technical problems of conventional preparations, which is prepared by the bilayer packing technique and comprises 5 to 60%, desirably 10 to 40% of a rapid release portion which can establish the therap... | 11/29/1994 |
| 5364620 | Controlled absorption diltiazem formulation for once daily administration A diltiazem pellet formulation for oral administration comprises a core of diltiazem or a pharmaceutically acceptable salt thereof in association with an organic acid, and a multi-layer membrane surrounding the core and containing a major proportion of a ... | 11/15/1994 |
| 5356625 | Microgranular preparation useful in the delivery of biologically active materials to the intestinal regions of animals A microgranular preparation having a core of biologically active material that is encapsulated by a water soluble film that is covered by an enteric coating of either an alkali soluble, acid insoluble polymer or a high molecular weight polymer whose struc... | 10/18/1994 |
| 5348748 | Pulsatile once-a-day delivery systems for minocycline Pharmaceutical delivery systems containing 7-dimethyl-6-deoxy-6-demethyltetracycline or a non-toxic acid addition salt thereof comprising mixtures of a minor proportion of slow-release blended polymer coated spherical granules adapted to release part of t... | 09/20/1994 |
| 5344657 | Microbeads of diltiazem, a process for their manufacture and a substained-release pharmaceutical composition containing them The microbeads are composed of a core containing the active ingredient and a microporous membrane, insoluble in aqueous medium, consisting of a film-forming polymer, a plasticizer and a filling material. The membrane has a thickness such that diltiazem is rele... | 09/06/1994 |
| 5336504 | Diltiazem formulations and methods of treatment A diltiazem pellet formulation for oral administration comprises a core of diltiazem or a pharmaceutically acceptable salt thereof in association with an organic acid, and a multi-layer membrane surrounding the core and containing a major proportion of a ... | 08/09/1994 |
