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| Number | Title | Issue Date |
| 6086915 | Compositions and methods of adjusting steroid hormone metabolism through phytochemicals The present invention relates to spray dried hydrophobic phytochemical chemopreventative compositions, a process for making such compositions and a method of using such compositions to adjust steroid metabolism in mammals. Typically, the hydrophobic dieta... | 07/11/2000 |
| 6086914 | Nonsedating formulations for allergic rhinitis which possess antihistaminic and anticholinergic activity It is perceived that the newer antihistamines, which have been developed so as to be less sedating relative to the "first generation" antihistamines, possess diminished anticholinergic effects on rhinorrhea, compared to first-generation antihistamines. It... | 07/11/2000 |
| 6086910 | Food supplements Disclosed is a flavonol-containing dry composition suitable for human consumption, together with uses thereof.... | 07/11/2000 |
| 6080426 | Process for encapsulation of caplets in a capsule and solid dosage forms obtainable by such process A process for encapsulation of caplets in a capsule comprises the following steps: a. providing empty capsule parts; b. filling at least one of said capsule parts with one or more caplets; c. putting said capsule parts together; and d. treating the combin... | 06/27/2000 |
| 6080418 | Suspensions of microcapsules containing biologically active ingredients and adhesive microspheres A composition comprising two suspensions: A) an aqueous suspension of microcapsules containing biologically active materials and B) an adhesive suspension of adhesive microspheres. The composition is useful for adhering microencapsulated biologically acti... | 06/27/2000 |
| 6077544 | Spheroids, preparation process and pharmaceutical compositions The present invention relates to a novel pharmaceutical form, in the form of spheroids, containing one or more active principles, which the exception of tiagabine. The invention also covers the process for the preparation of such spheroids and multipartic... | 06/20/2000 |
| 6077513 | Drug for treatment of bilharziasis (Schistosomiasis) The method of extracting volatile oils from Commiphora molmol includes the steps of grinding up the Commiphora molmol plant; covering the ground up plant with a layer of water to create a mixture of plant and water; passing steam through the mixture of wa... | 06/20/2000 |
| 6074670 | Fenofibrate pharmaceutical composition having high bioavailability and method for preparing it The invention provides an immediate-release fenofibrate composition comprising (a) an inert hydrosoluble carrier covered with at least one layer containing fenofibrate in a micronized form having a size less than 20 μm, a hydrophilic polymer and, optiona... | 06/13/2000 |
| 6071536 | Gelatin capsule having adjusted water activity A gelatin capsule having adjusted water activity and preserved in a closed system, which contains, packed herein, an additive(s) selected from the group consisting of carboxymethyl cellulose calcium, crosscarmellose sodium, partially gelatinized starch an... | 06/06/2000 |
| 6068834 | Skin lightening compositions This invention relates to compositions, compounds and methods for lightening skin, using active compounds having the structure: ##STR1## wherein: (i) each X is, independently, selected from the group consisting of halo, alkyl, substituted alkyl, aryl... | 05/30/2000 |
| 6068854 | Sol-controlled thermocolloid matrix based on gelatin for oral sustained-release form A peroral depot medicament with controlled active substance release is composed of a gelatine matrix that continuously dissolves in an aqueous medium above 37° C., and a medicament distributed therein. The release of the medicament, that may be easily or... | 05/30/2000 |
| 6066332 | Immediate-effect ibuprofen-containing medicament and its use A medicament for immediately treating painful, inflammatory and/or febrile diseases contains as active substance ibuprofen as a racemate, as a racemic mixture with its enantiomers, as a pseudoracemate (mixtures of equal parts of S- and R-ibuprofen) or as ... | 05/23/2000 |
| 6063762 | Cyclosporin-containing microemulsion preconcentrate composition The present invention relates to a microemulsion preconcentrate composition comprising (1) cyclosporin as an active component; (2) alkyl ester of polycarboxylic acid and/or carboxylic acid ester of polyols as a lipophilic solvent; (3) oil; and (4) surfact... | 05/16/2000 |
| 6063401 | Plantago major and hypericum perforatum compound for use in treating a tobacco or nicotine habit A composition containing the herbs Plantago major and Hypericum perforatum is presented. Use of the composition, of the present invention, in a form adapted to be orally ingested produces a diminished desire for tobacco (i.e., nicotine) without the use of... | 05/16/2000 |
| 6060084 | Method for preparing a core material containment system and the core material containment system prepared thereby A method for preparing a core material containment system which prevents or controls leaching of the core material from the containment system, said method comprising the steps of: (1) providing a shell material having a softening temperature above about ... | 05/09/2000 |
| 6056971 | Method for enhancing dissolution properties of relatively insoluble dietary supplements and product incorporating same A method for enhancing the dissolution properties of relatively insoluble dietary supplements is provided in accordance with the invention. The method includes the steps of providing at least one relatively water insoluble dietary supplement, solubilizing... | 05/02/2000 |
| 6045825 | Plantago major and Piper methysticum compound for use in treating a tobacco or nicotine habit A composition containing the herbs Plantago major and Piper methysticum is presented. Use of the composition, of the present invention, in a form adapted to be orally ingested produces a diminished desire for tobacco (i.e., nicotine) without the use of ni... | 04/04/2000 |
| 6039958 | Stabilized live vaccine A stabilized live vaccine containing a varicella virus and a stabilizer, wherein the vaccine is substantially free of Ca2+ ions and Mg2+ ions is described. This stabilized live vaccine is excellent in storage stability and heat res... | 03/21/2000 |
| 6039979 | Multiparticulate pharmaceutical form with programmed and pulsed release and process for its preparation The invention relates to a multiparticulate pharmaceutical form with delayed and pulsed release, enabling to obtain the onset of the availability of the active ingredient within 4 to 8 hours after the ingestion of the pharmaceutical form, and then a progr... | 03/21/2000 |
| 6030641 | Sustained release capsule and method for preparing the same A sustained release capsule in which an outer surface of a hard capsule mainly composed of gelatin and containing a physiologically active substance is uniformly covered with a film material comprising a natural polysaccharide/polyhydric alcohol compositi... | 02/29/2000 |
| 6030642 | Extended release clonidine formulation (capsule) A method of providing a patient needing clonidine with an extended dosage of clonidine over a prolonged period of time. Such method involves administering to the patient an oral dosage unit comprising a homogenous mixture of a therapeutically effective am... | 02/29/2000 |
| 6027748 | Pharmaceutical tablet, completely coated, for controlled release of active principles that present problems of bio-availability linked to gastro-intestinal absorption Described herein is a particular type of pharmaceutical tablet, for oral use, which is formed by one or more layers, and is specifically designed for controlled release of active principles that present problems of bio-availability linked to absorption in... | 02/22/2000 |
| 6027746 | Chewable soft gelatin-encapsulated pharmaceutical adsorbates The present invention relates to novel liquid oral suspensions incorporated within a soft gelatin capsule comprised of a bitter or bad-tasting pharmaceutical active (such as antihistamines, decongestants and the like) which is dispersed within an adsorbat... | 02/22/2000 |
| 6024980 | Multiphase soft gelatin dosage form The present invention relates to a dosage form containing a common enclosure of polymeric material. The enclosure contains multiple phases of semi-solid fill materials containing active ingredients.... | 02/15/2000 |
| 6022562 | Medicinal and/or nutritional microcapsules for oral administration The present invention relates to microcapsules for the oral administration of medicinal and/or nutritional active principles (AP), which are smaller than or equal to 1000 μm in size. These microcapsules consist of particles which are coated with a coatin... | 02/08/2000 |
| 6018033 | Hydrophilic, hydrophobic, and thermoreversible saccharide gels and forms, and methods for producing same Polymerizable saccharide monomers are made by the reaction of a saccharose and a (meth)acrylate. Hydrophilic, hydrophobic and thermoreversible gels and foams are formed upon polymerization of the saccharide monomers. Hydrophilic sucrose monomers are synth... | 01/25/2000 |
| 6004580 | Pharmaceutical compositions derived from microemulsion-based gels A pharmaceutical composition containing a microemulsion made up of a hydrophilic component, a lipophilic component, a surfactant and a drug, where the hydrophilic component, the lipophilic component and the surfactant form, when examined on a macroscopic ... | 12/21/1999 |
| 6004558 | Methods for treating cancer with legume plant extracts The present invention relates to the preparation of therapeutic compositions comprising extracts of leguminous plants from which the isoflavones genistein, daidzein, formononetin and biochanin and/or their glycosides have been removed. The invention also ... | 12/21/1999 |
| 6001384 | Method for fighting against myiasis affecting cattle and sheep populations and compositions for implementing same Process for controlling myiasis in cattle and sheep livestock and compositions for carrying out this process. Composition for topical or parenteral use for controlling myiasis in cattle and sheep, with an effective larvicidal amount of a compound of formula I,... | 12/14/1999 |
| 5993853 | Dietary supplement A dietary supplement comprising a reaction product of sodium bicarbonate and apple cider vinegar which is lyophilized.... | 11/30/1999 |
| 5989578 | Associations of active principles containing clopidogrel and an antithrombotic agent The invention relates to a pharmaceutical composition containing an association of active principles, wherein the active principles are clopidogrel and aspirin, each constituent being present in a free form or in the form of a pharmaceutically acceptable ... | 11/23/1999 |
| 5989583 | Solid lipid compositions of lipophilic compounds for enhanced oral bioavailability Lipophilic substances of poor oral bioavailability are mixed with at least one solid fat and phospholipid to obtain a dried solid composition suitable as an oral dosage form. The solid lipid compositions are exemplified for food additives or dietary suppl... | 11/23/1999 |
| 5989557 | Process for extracting polyphenol fractions of tea and compositions produced therewith The present invention relates to the preparation of novel polyphenol fractions of Camellia sinensis (tea), the use thereof and formulations containing them. The invention relates specifically to the preparation of extracts deprived of caffeine but contain... | 11/23/1999 |
| 5985321 | Soft gelatin capsule manufacture Soft gelatin capsules having a capsule shell comprising gelatin, plasticizers and, if desired or required, further auxiliary agents, and a capsule filling containing a solvent including a migrateable solvent such as 1,2-propyleneglycol as a solvent in the... | 11/16/1999 |
| 5976577 | Process for preparing fast dispersing solid oral dosage form Process is provided for preparing an oral solid rapidly disintegrating freeze-dried dosage form of a pharmaceutically active substance having an unacceptable taste, wherein prior to freeze drying, a suspension of uncoated or coated coarse particles of a p... | 11/02/1999 |
| 5968551 | Orally administrable opioid formulations having extended duration of effect Sustained release oral solid dosage forms of opioid analgesics are provided as multiparticulate systems which are bioavailable and which provide effective blood levels of the opioid analgesic for at least about 24 hours. A unit dose of the opioid analgesi... | 10/19/1999 |
| 5968552 | Diltiazem hydrochloride formulation The invention relates to a pharmaceutical formulation comprising diltiazem hydrochloride. The formulation is in the form of a mixture of beads blended so as to provide a dissolution profile that renders the formulation suitable for oral administration onc... | 10/19/1999 |
| 5968550 | Liquisolid systems and methods of preparing same Liquisolid systems are acceptably flowing and compressible powdered forms of liquid medications. According to the concept of liquisolid systems, liquid lipophilic drugs, or water-insoluble solid drugs dissolved in suitable non-volatile solvents, may be co... | 10/19/1999 |
| 5965161 | Extruded multi-particulates A unit dose sustained-release oral dosage form containing a plurality of melt-extruded particles, each consisting essentially of a therapeutically active agent, one or more retardants, and an optional water-insoluble binder is disclosed. The particles hav... | 10/12/1999 |
| 5958429 | Potentiation of serotonin response The availability of serotonin, norepinephrine and dopamine in the brain is increased by administering a serotonin reuptake inhibitor with a serotonin 1A antagonist and L-tryptophan or 5-hydroxy-L-tryptophan.... | 09/28/1999 |
