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Patent No. 6099319

Neuroimaging as a Marketing Tool

Neuroimaging as a means for validating whether a stimulus such as advertisement, communication, or product evokes a certain mental response such as emotion, preference, or memory, or to predict the consequences of the stimulus on later behavior such as consumption or purchasing.

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Class 424/450 - Liposomes


Subclass of Class 424 - Drug, bio-affecting and body treating compositions
Definition: Subject matter in which the special physical form is a pharmaceutical
No. of patents: 3103
Last issue date: 05/29/2012


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NumberTitleIssue Date
7238368Releasable linkage and compositions containing same
A conjugate comprised of a hydrophilic polymer covalently yet reversibly linked to a amine-, hydroxy- or carboxyl-containing ligand is described. The resulting conjugate is capable of releasing the parent amine, hydroxy, or carboxyl-containing compound via thiol-med...
07/03/2007
7238367Liposome loading with metal ions
This invention relates to encapsulation of drugs and other agents into liposomes. ...
07/03/2007
7238366Submicron liposome suspensions obtained from preliposome lyophilizates
This invention provides an aqueous/t-butanol solvent-system, facile reconstitute, submicron-reconsitiute preliposome-lyophilaye and method of its preparation and use. In one embodiment this entails a modified method for the preparation of a submicron and stab...
07/03/2007
7238369Cationic liposome delivery of taxanes to angiogenic blood vessels
Angiogenic endothelial cells are selectively targeted with lipid/DNA complexes or cationic liposomes containing a substance which affects the targeted cells by inhibiting or promoting their growth. A site of angiogenesis can be precisely located by administering cat...
07/03/2007
7238372Methods for inhibiting tumor cell proliferation
The subject invention concerns methods for inhibition of STAT biological functions using platinum complexes. ...
07/03/2007
7238361Smart drug delivery system
The present invention provides prodrug and multi-prodrug complexes comprising drugs specifically bound to synthetic receptors in such a manner that active drug becomes available only in the presence of a targeted pathophysiologic receptor. Methods for preparation an...
07/03/2007
7238665Peptide marker targeting to nasopharyngeal carcinoma cell and application thereof
The present invention provides a peptide marker targeting to nasopharyngeal carcinoma (NPC) cells and application thereof. The peptide binds specifically to the cell surface of NPC cells. After conjugated with liposome containing chemotherapeutic drugs, such peptide...
07/03/2007
7235259Pharmaceutical compositions of cholesteryl ester transfer protein inhibitors
A pharmaceutical composition comprises a solid amorphous dispersion of a cholesteryl ester transfer protein inhibitor and a concentration-enhancing polymer. ...
06/26/2007
7235583Fatty acid-anticancer conjugates and uses thereof
The invention provides conjugates of fatty acids and anticancer agents useful in treating cancer, and compositions and formulations thereof. Methods for using the conjugates also are provided. ...
06/26/2007
7235248Pharmaceutical compositions comprising cyclosporins
Pharmaceutical compositions comprising a cyclosporin, e.g. Ciclosporin or [Nva]2-Ciclosporin, in “microemulsion pre-concentrate” and microemulsion form. The compositions typically comprise (1.1) a C1-5alkyl or tetrahydrofurfuryl di- or part...
06/26/2007
7235255Biological bioadhesive compositions and methods of preparation and use
The present invention relates generally to the preparation and use of biological tissue adhesives which rely on combining fibrinogen and thrombin. More particularly, the present invention relates to a method of preparing a fibrin sealant whereby said sealant is form...
06/26/2007
7235043System for implanting an implant and method thereof
A system for implanting an implant and method thereof is disclosed. In general overview, the system includes an implant, an envelope enclosing the implant, a delivery assembly and an attachment piece for attaching the envelope or implant to the delivery assembly. Th...
06/26/2007
7235227Paramagnetic particles that provide improved relaxivity
An improved contrast agent for magnetic resonance imaging comprises particles to each of which is coupled a multiplicity of chelating agents containing paramagnetic ions. In the improved agent, the position of the ion is offset from the surface of the particle so as...
06/26/2007
7232688Systems and methods for preparing and analyzing low volume analyte array elements
Methods for dispensing tools that can be employed to generate multi-element arrays of sample material on a substrate surface. The resulting substrates are also provided. The substrates surfaces can be flat or geometrically altered to include wells of receiving mater...
06/19/2007
7229611Clear personal care compositions containing visible capsules
Disclosed are clear antiperspirant or deodorant compositions that include visible capsules. ...
06/12/2007
7229633Biological bioadhesive compositions and methods of preparation and use
The present invention relates generally to the preparation and use of biological tissue adhesives which rely on combining fibrinogen and thrombin. More particularly, the present invention relates to a method of preparing a fibrin sealant whereby said sealant is form...
06/12/2007
7229604Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging
The invention provides, in a general sense, a new labeling strategy employing 99mTc chelated with ethylenedicysteine (EC). EC is conjugated with a variety of ligands and chelated to 99mTc for use as an imaging agent for tissue-specific diseases...
06/12/2007
7229638Biopolymer marker indicative of disease state having a molecular weight of 1525 Daltons
The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopoly...
06/12/2007
7229473Local delivery of rapamycin for treatment of proliferative sequelae associated with PTCA procedures, including delivery using a modified stent
Methods of preparing intravascular stents with a polymeric coating containing macrocyclic lactone (such as rapamycin or its analogs), stents and stent graphs with such coatings, and methods of treating a coronary artery with such devices. The macrocyclic lactone-bas...
06/12/2007
7229959Supplemented fibrin matrix delivery systems
This invention provides supplemented and unsupplemented tissue sealants as well as methods for their production and use thereof. Disclosed are tissue sealants supplemented with at least one antibody. The composition may be further supplemented with, for example, one...
06/12/2007
7229973pH-sensitive polymeric micelles for drug delivery
Mixed micelles containing poly(L-histidine)-poly(ethylene glycol) block copolymer and poly(L-lactic acid)-poly(ethylene glycol) block copolymer are a pH-sensitive drug carrier that release the drug in an acidic microenvironment, but not in the blood. Since the micro...
06/12/2007
7230088Compounds for dual photodiagnosis and therapy
The invention discloses compounds and compositions for dual phototherapy and combined therapy and diagnosis of tumors and other lesions. The compounds have a Dye that, when photoactivated, operates via Type I and/or Type II mechanisms. Other Dye or azide components ...
06/12/2007
7230131Carnitine-magnesium hydroxycitrate
A method for preparing, from at least one hygroscopic substance, mixtures that can be granulated and that have little hygroscopicity. The corresponding mixtures, especially carnitine-magnesium citrate and carnitine-magnesium hydroxycitrate, are produced. ...
06/12/2007
7226581Bodywashes containing additives
The invention encompasses bodywashes containing an additive. The additive may contain a sunscreen. The additive may contain 2, 3, or more than three sunscreens. Optionally, one or more of the sunscreens may be encapsulated. The invention further encompasses methods ...
06/05/2007
7226582Sunscreen compositions and methods of use
The invention encompasses additives for addition to a bodywash, where the additives contain one or more sunscreens, and where a bodywash which contains the additive imparts to the skin an SPF of at least about 2, in some cases at least about 5, or 10, or 15. Also de...
06/05/2007
7226615Expandable foam-like biomaterials and methods
Liquid, injectable, aqueous solutions are transformed in situ to an expandable foam-like, space filling, and adherent biomaterial. Preferably, the foam-like biomaterial is the reaction product of a two-part liquid system to achieve the in situ formation thereof. The...
06/05/2007
7226758Nucleic acids encoding glial cell line-derived neurotrophic factor (GDNF)
A novel neurotrophic factor referred to as glial cell line-derived neurotrophic factor (GDNF) has been identified and isolated from serum free growth conditioned medium of B49 glioblastoma cells. Rat and human genes encoding GDNF have been cloned and sequenced. A ge...
06/05/2007
7226932Self-emulsifying drug delivery system
Oral pharmaceutical formulation which improves the bioavailability of pharmaceuticals which are substantially water and oil insoluble is disclosed. In addition to the pharmaceutical, the formulation includes an emulsifier, an oil and an solubilizer. Alternatively, t...
06/05/2007
7223770Tocopherol-modified therapeutic drug compounds
Tocopherol-modified therapeutic drug compounds; emulsion, microemulsion, and micelle formulations that include the compounds; methods for making the compounds and formulations; methods for administering the compounds and formulations; and methods for treating condit...
05/29/2007
7223826Amide-functional polymers, compositions, and methods
Amide-functional polymers, and compositions including such polymers, are disclosed. The compositions, which optionally may be hardenable, are useful for treating a surface. ...
05/29/2007
7223571Targeted glycosaminoglycan polymers by polymer grafting and methods of making and using same
The present invention relates to methodology for polymer grafting by a polysaccharide synthase and, more particularly, polymer grafting using the hyaluronate or chondroitin or heparin/heparosan synthases from Pasteurella, in order to create a variety of glyco...
05/29/2007
7225082Colloidal rod particles as nanobar codes
Freestanding particles comprising a plurality of segments, wherein the particle length is from 20 nm to 50 μm and the particle width is form 5 nm to 50 μm. ...
05/29/2007
7223381Pressurised metered dose inhalers (MDI)
The invention relates to the use of pressurized metered dose inhalers (MDIs) having part or all of their internal surfaces consisting of stainless steel, anodized aluminum or lined with an inert organic coating; and to compositions to be delivered with said MDIs.
05/29/2007
7223406Methods and compositions for preventing and treating male erectile dysfunction and female sexual arousal disorder
The invention provides a method for preventing or treating male erectile dysfunction or female sexual arousal disorder by administering an effective amount of one or more factors from a group of factors including vascular endothelial growth factor, brain-derived neu...
05/29/2007
7223887Multivalent cationic lipids and methods of using same in the production of lipid particles
A multivalent cationic lipid having a positively-charged head group including two quaternary amine groups and a hydrophobic portion including four hydrocarbon chains, which may be the same or different and which are optionally substituted alkyl and alkenyl groups, t...
05/29/2007
7223380Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging
The invention provides, in a general sense, a new labeling strategy employing 99mTc chelated with ethylenedicysteine (EC). EC is conjugated with a variety of ligands and chelated to 99mTc for use as an imaging agent for tissue-specific diseases...
05/29/2007
7220853Inhibition of chronic myelogenous leukemic cell growth by liposomal-antisense oligodeoxy-nucleotides targeting to Grb2 or Crk1
The present invention provides novel compositions and methods for use in the treatment of cancer, specifically, in the treatment of chronic myelogenous leukemia (CML). The compositions contain antisense oligonucleotides that hybridize to Grb2 and Crkl nucleic acids,...
05/22/2007
7220726Antifungal pimaricin compositions and therapeutic methods employing same
An antifungal composition suitable for parenteral administration to a mammal includes an amount of pimaricin or an antifungal derivative thereof that is effective to inhibit the growth of a fungal infection in a mammal; a pharmaceutically acceptable dipolar aprotic ...
05/22/2007
7220778Methods and devices for epithelial protection during photodynamic therapy
Methods for preventing damage to epithelial tissue during PDT induced using a photosensitizing agent or pre-photosensitizing agent are provided. The methods of the present invention utilize spatial confinement to control photoactivation of the photoactive species to...
05/22/2007
7220824Integrin-mediated drug targeting
The present invention relates to cytostatics which have a tumour-specific action as a result of linkage to αvβ3 integrin antagonists via preferred linking units. The preferred linking units guarantee serum stability of the conjugate of cytost...
05/22/2007
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