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Class 424/450 - Liposomes


Subclass of Class 424 - Drug, bio-affecting and body treating compositions
Definition: Subject matter in which the special physical form is a pharmaceutical
No. of patents: 3103
Last issue date: 05/29/2012


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NumberTitleIssue Date
7300662Drug/drug delivery systems for the prevention and treatment of vascular disease
A drug and drug delivery system may be utilized in the treatment of vascular disease. A local delivery system is coated with rapamycin or other suitable drug, agent or compound and delivered intraluminally for the treatment and prevention of neointimal hyperplasia f...
11/27/2007
7300676Herbal composition for treatment of digestive and urinary disorders
The present invention includes compositions and methods of treating and preventing prostate and urinary problems in human males. Additionally, methods of digestive system improvement, blood circulation system improvement, liver and kidney system improvement and urin...
11/27/2007
7300667Preparations for the application of anti-inflammatory, especially antiseptic agents and/or agents promoting the healing of wounds, to the lower respiratory tract
Disclosed are compositions comprising antiseptic and wound healing agents for the treatment of diseases of the lower respiratory tract and methods. ...
11/27/2007
7300954Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof
The present invention provides an antiproliferative compound having a structural formula where X and Y independently are oxygen, nitrogen or sulfur; R1 is alkyl, alkenyl, alkynyl, aryl, heteroaryl, carbo...
11/27/2007
7297759Peptides for increasing transfection efficiency
The present application discloses a transfection effective carrier polypeptide comprising derivatives of HIV Tat peptide. ...
11/20/2007
7297325Hydrophilic light absorbing compositions for determination of physiological function
Highly hydrophilic indole and benzoindole derivatives that absorb and fluoresce in the visible region of light are disclosed. These compounds are useful for physiological and organ function monitoring. Particularly, the molecules of the invention are useful for opti...
11/20/2007
7297344Preparations for the promotion of wound healing in the upper respiratory tract and/or ear
Use of anti-inflammatory agents such as povidone iodine for the preparation of a pharmaceutical composition for the treatment of diseases of the upper respiratory tract and/or the ear which are susceptible to the administration of such agents. ...
11/20/2007
7294620Lipid analogs for inhibiting HIV-1 activity
The invention relates to methods of treating viral infections, and in particular hepatitis B virus. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative to inhibit the ...
11/13/2007
7294619Lipid analogs for inhibiting the activity of hepatitis B antigen
The invention relates to methods of treating viral infections, and in particular hepatitis B virus. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative to inhibit the ...
11/13/2007
7294621Lipid analogs for combating tumors
The invention relates to methods of treating viral infections, and in particular hepatitis B virus. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative to inhibit the ...
11/13/2007
7294511Methods for delivering nucleic acid molecules into cells and assessment thereof
Methods for delivering nucleic acid molecules into cells and methods for measuring nucleic acid delivery into cells and the expression of the nucleic acids are provided. The methods are designed for introduction of large nucleic acid molecules, including artificial ...
11/13/2007
7294278Method for oxygenating wastewater
A method and apparatus creates gas-enriched fluid that is used to treat wastewater. In one embodiment, the wastewater is withdrawn from a supply of wastewater to be treated, and the wastewater is delivered in an atomized manner to a vessel pressurized with gas to fo...
11/13/2007
7288243Aerosol drug inhibition of lung metastases
The present invention provides a method of inhibiting growth of lung metastases in an individual comprising the steps of administering a dose of a lipid-drug enhancer liposomal complex and, in sequence, administering a dose of a lipid-anticancer drug liposomal compl...
10/30/2007
7288266Liposome complexes for increased systemic delivery
Highly efficient cationic liposomes have been developed as an improved delivery system for biologically-active reagents. A novel structure, the sandwich liposome, is formed and comprises one or more biologically active agents internalized between two bilomellar lipo...
10/30/2007
7285544Use of nitroxides in treating skin disease
Methods of treating inflammatory skin diseases such as rosacea, atopic dermatitis, contact dermatitis, drug eruptions, psoriasis, seborrheic dermatitis, connective tissue diseases, autoimmune disorders, urticaria or hives, and inflammation associated with skin infec...
10/23/2007
7285288Inhibition of Bcl-2 protein expression by liposomal antisense oligodeoxynucleotides
The present invention provides novel compositions and methods for use in the treatment of Bcl-2-associated diseases like cancer, specifically, in the treatment of follicular lymphoma (FL). The compositions contain antisense oligonucleotides that hybridize to Bcl-2 n...
10/23/2007
7285631Human cDNAs and proteins and uses thereof
The invention concerns GENSET polynucleotides and polypeptides. Such GENSET products may be used as reagents in forensic analyses, as chromosome markers, as tissue/cell/organelle-specific markers, in the production of expression vectors. In addition, they may be use...
10/23/2007
7285422Systems and methods for preparing and analyzing low volume analyte array elements
The invention provides methods for dispensing tools that can be employed to generate multi-element arrays of sample material on a substrate surface. The substrates surfaces can be flat or geometrically altered to include wells of receiving material. The tool can dis...
10/23/2007
7285540Medicament comprising HGF gene
The present invention relates to a medicament comprising a HGF gene. The medicament of the present invention may be topically applied to the target organs so that the effects can be selectively exhibited, resulting in minimizing the side effects of HGF. ...
10/23/2007
7285157Air filter
An air-filter for a circulating and/or recirculating air system using a filter medium containing a microbiologically effective amount of a polymeric biguanide or salt thereof. Also claimed is a method for reducing odors and/or air-borne micro-organisms in a circulat...
10/23/2007
7285289Nanoparticle vaccines
The present invention relates to nanoparticle vaccines comprised of a carrier, particularly polymerized lipids, having multiple copies of an antigen or combinations of different antigens displayed on the carrier. Such antigen-displaying nanoparticles may also displa...
10/23/2007
7285622Releasable linkage and compositions containing same
A compound comprised of a hydrophilic polymer covalently yet reversibly linked to a amine-containing ligand through a dithiobenzyl linkage is described. ...
10/23/2007
7282215Supports for photosensitizer formulations
The invention is generally related to the field of formulating medicaments in association with a solid support. Such formulations comprising photosensitizers, and their use in photodynamic therapy, are also provided. Methods for the production of the medicament form...
10/16/2007
7282221Antiviral product, use and formulation thereof
An antiviral product is comprised of at least three dosages forms, each of which has a different release profile, with the Cmax for the antiviral product being reached in less than about twelve hours. In one embodiment, there is an immediate release dosag...
10/16/2007
7279597Phenyl amine carboxylic acid compounds and compositions for delivering active agents
Phenyl amine carboxylic acid compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. ...
10/09/2007
7279150Chelating agents with lipophilic carriers
Compounds useful for associating with nanoparticle or microparticle emulsions to obtain magnetic resonance images permit control of the relaxivity of the signal and readily associate with the particulate components. ...
10/09/2007
7279154Use of comb copolymers based on acryloyldimethyltaurine acid in cosmetic, pharmaceutical and dermatological products
The invention relates to uses of comb polymers of acryloyldimethyltaurine and/or acryloyldimethyltaurates in cosmetic, pharmaceutical and dermatological applications as thickeners, dispersing agents, suspending agents, emulsifiers, stabilizers, solubilizers, conditi...
10/09/2007
7279163Water-in-oil emulsion vaccines
Oil-in-Water emulsion vaccines induce higher biliary IgA responses which decrease mucosal/internal organ invasion and fecal shedding, increase specific activity of serum IgG subpopulations, and increase the relative avidity index of serum IgG subpopulations, resulti...
10/09/2007
7279494Antimicrobial [3.1.0] bicyclohexylphenyl-oxazolidinone derivatives and analogues
The present invention provides certain [3.1.0] bicyclic oxazolidinone derivatives of formula I or pharmaceutically acceptable salts or prodrugs thereof that are antibacterial agents, pharmaceutical compositions c...
10/09/2007
7279179Liposome-entrapped topoisomerase inhibitors
A composition for administration of a therapeutically effective dose of a topoisomerase inhibitor I or topoisomerase I/II inhibitor is described. The composition includes liposomes having an outer surface and an inner surface defining an aqueous liposome compartment...
10/09/2007
7276248Conjugate having a cleavable linkage for use in a liposome
Conjugates of a hydrophobic moiety, such as a lipid, linked through a cleavable dithiobenzyl linkage to a therapeutic agent are described. The dithiobenzyl linkage is susceptible to cleavage by mild thiolysis, resulting in release of the therapeutic agent in its ori...
10/02/2007
7276254Emulsion/aggregation polymeric microspheres for biomedical applications and methods of making same
A method of forming polymeric microspheres for biomedical applications includes forming polymeric microspheres by an emulsion/aggregation process from a precursor monomer species, and treating the polymeric microspheres to attach a biomedical functional material to ...
10/02/2007
7276579Immunogenic proteoliposomes, and uses thereof
An immunogenic proteoliposome containing a transmembrane protein or oligomeric complexes containing such proteins, including viral envelope glycoproteins, in a lipid membrane around an elliptoid or spherical shape. The shape preferably also contains an attractant su...
10/02/2007
7273722Neurotoxins with enhanced target specificity
Modified neurotoxins that contain protease cleavage sites susceptible uniquely to proteases present in certain tissues are described. The toxins can be selectively activated by proteases in muscle or selectively inactivated by proteases in blood. ...
09/25/2007
7273932Antisense oligonucleotides for fertility and menstrual cycle regulation and for chemopreventive and chemotherapeutic use
The invention relates to antisense oligonucleotides, in particular to antisense oligonucleotides to receptor genes, and the use of such oligonucleotides to regulate reproductive function and as chemopreventive or as a chemotherapeutic for various cancers, especially...
09/25/2007
7273620Triggered release of liposomal drugs following mixing of cationic and anionic liposomes
Methods and compositions for triggering the delivery of an encapsulated therapeutic agent from a liposome are provided. Liposomes of opposite charge and incorporating lipids which favor non-lamellar structures are contacted in vivo. At least one of the liposome enca...
09/25/2007
7273618Method for administering agents to the central nervous system
The present invention is directed to a method for delivering agents to the central nervous system by way of a tissue innervated by the trigeminal nerve that is outside the nasal cavity. Such a method of delivery can be useful in the treatment of central nervous syst...
09/25/2007
7273604Anti-asthmatic combinations comprising surface active phospholipids
Disclosed is a combination product for use in treating asthma and other respiratory conditions comprising a medicament comprising a surface active phospholipid composition in the form of a fine powder and an antiasthma drug. The product is arranged to be administere...
09/25/2007
7271154Antibiotic conjugates
This invention features a compound of the following formula: wherein T is a transportophore, L is a bond or linker, and C is an antibiotic therapeutic agent, the transportophore is covalently bonded to the antibi...
09/18/2007
7271156Immunostimulatory nucleic acids
The invention relates to immunostimulatory nucleic acid compositions and methods of using the compositions. The T-rich nucleic acids contain poly T sequences and/or have greater than 25% T nucleotide residues. The TG nucleic acids have TG dinucleotides. The C-rich n...
09/18/2007
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