Class 424/450 - Liposomes

Subclass of Class 424 - Drug, bio-affecting and body treating compositions
Definition: Subject matter in which the special physical form is a pharmaceutical
No. of patents: 3090
Last issue date: 02/07/2012

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Number	Title	Issue Date
8110218	Compositions and methods for less immunogenic protein-lipid complexes The present invention provides compositions and methods for reducing the immunogenicity and increasing the circulating half-life of therapeutic proteins such as Factor VIII. The compositions comprise lipidic structures such as liposomes, micelles and cochleates comp...	02/07/2012
8110217	Sphingomyelin liposomes for the treatment of hyperactive bladder disorders The present invention provides pharmaceutical compositions and methods for the instillation of lipid vehicles comprised of liposomes containing sphingomyelin or sphingomyelin metabolites to prevent, manage, ameliorate and/or treat disorders involving neuropathic pai...	02/07/2012
8097276	Method for coating particle with lipid film A method for coating an object, i.e. a particle, with two sheets of lipid film having a space formed there between. In the method for coating a particle having a positive electrostatic-charging property with two sheets of lipid film, the particle having a positive e...	01/17/2012
8097277	Charge-dynamic polymers and delivery of anionic compounds The present invention provides dynamic charge state cationic polymers that are useful for delivery of anionic molecules. The dynamic charge state cationic polymers are designed to have cationic charge densities that decrease by removal of removable functional groups...	01/17/2012
8092828	Fixed drug ratios for treatment of hematopoietic cancers and proliferative disorders Provided herein are methods for treating cancer by administering a pharmaceutical composition comprising a fixed, non-antagonistic molar ratio of cytarabine and an anthracycline. Such methods are particularly useful in the treatment of patients with advanced hematol...	01/10/2012
8084057	Compositions and methods for wound healing The present invention is related to the field of wound healing or tissue regeneration due to disease (i.e., for example, cardiovascular diseases, osteoarthritic diseases, or diabetes). In particular, the present invention provides compositions and methods comprising...	12/27/2011
8084056	Preparation of a lipid blend and a phospholipid suspension containing the lipid blend The present invention describes processes for the preparation of a lipid blend and a uniform filterable phospholipid suspension containing the lipid blend, such suspension being useful as an ultrasound contrast agent. ...	12/27/2011
8080262	Encapsulated peptide amphiphile nanostructures The present invention provides compositions and methods for creating encapsulated peptide amphiphilic nanostructures useful in treating diseases. In particular, the present invention provides compositions and methods for preparing peptide amphiphile nanostructures t...	12/20/2011
8075913	Method of producing a cationic liposomal preparation comprising a lipophilic compound A method for producing a cationic liposomal preparation comprising a lipophilic active compound with physical and chemical stability during manufacturing, storing and reconstituting, and further a cationic liposomal preparation obtainable by this method as well as s...	12/13/2011
8071127	Dual action, inhaled formulations providing both an immediate and sustained release profile Methods for formulating immediate and sustained release anti-infectives and delivery of such for treatment of respiratory tract infections and other medical conditions, and devices and formulations used in connection with such are described. ...	12/06/2011
8062663	Methods and compostions for enhancing transdermal drug delivery Methods and compositions for enhancing transdermal delivery of a bioactive agent. The method contains the step of applying to a skin tissue an effective amount of a composition comprising: (a) a drug vehicle; (b) a bioactive agent encapsulated within the drug vehicl...	11/22/2011
8062662	Liposomes containing an entrapped compound in supersaturated solution A liposome composition having a compound entrapped in a supersaturated solution and method for preparing such a composition are described. ...	11/22/2011
8058254	DNA vaccines encoding heat shock proteins The present invention is related to a method of treating a T cell-mediated inflammatory autoimmune disease by administering to an individual in need thereof an immunogenic composition comprising a recombinant construct of a nucleic acid sequence encoding heat shock ...	11/15/2011
8048448	Nanoshells for drug delivery Nano-constructs comprising nanoshells and methods of using the nano-constructs for treating or ameliorating a medical condition are provided. ...	11/01/2011
8034375	Combinations and modes of administration of therapeutic agents and combination therapy The present invention provides combination therapy methods of treating proliferative diseases (such as cancer) comprising a first therapy comprising administering to an individual an effective amount of a taxane in a nanoparticle composition, and a second therapy wh...	10/11/2011
8034376	Lipid containing formulations Compositions and methods useful in administering nucleic acid based therapies, for example association complexes such as liposomes and lipoplexes are described. ...	10/11/2011
8021686	Lipid-encapsulated polyanionic nucleic acid Methods for the preparation of a lipid-nucleic acid composition are provided. According to the methods, a mixture of lipids containing a protonatable or deprotonatable lipid, for example an amino lipid and a lipid such as a PEG- or Polyamide oligomer-modified lipid ...	09/20/2011
8017147	Nutritional supplement for the prevention of cardiovascular disease, alzheimer's disease, diabetes, and regulation and reduction of blood sugar and insulin resistance A synergistic mixture (which may be utilized as a food or a drink or a supplement or a drug or a cosmetic or a hygienic product) that is formulated and is capable of improving a person's well being, lowering the risks of cardiovascular and/or Alzheimer's diseases an...	09/13/2011
7993672	Stable lipid-comprising drug delivery complexes and methods for their production Novel stable, concentrated, biologically active and ready-to-use lipid-comprising drug delivery complexes and methods for their production are described. The biological activity of the complexes produced are comparable to the formulations prepared according to the p...	08/09/2011
7985417	Method of lipid structure preparation A method of inserting a lipid-linked moiety into a lipid assembly, such as a planar lipid monolayer or bilayer, a spherical lipid vesicle, a micelle, or an emulsion envelope monolayer is described. In the method, the lipid assembly and the lipid-linked moiety are co...	07/26/2011
7981442	Ultrasound enhancement of drug release across non-ionic surfactant membranes A method of targeted drug delivery and imaging using nonionic surfactant vesicles (niosomes) in combination with ultrasound. Niosomes have potential applications in targeted drug delivery and imaging because of their ability to encapsulate therapeutic agents and the...	07/19/2011
7976868	Liposomes comprising duramycin and anti-viral agents Disclosed are surprising discoveries concerning the role of anionic phospholipids and aminophospholipids in tumor vasculature and in viral entry and spread, and compositions and methods for utilizing these findings in the treatment of cancer and viral infections. Al...	07/12/2011
7968115	Liposomal curcumin for treatment of cancer The present invention provides a compositions and methods for the treatment of cancer, including pancreatic cancer, breast cancer and melanoma, in a human patient. The methods and compositions of the present invention employ curcumin or a curcumin analogue encapsula...	06/28/2011
7968116	Antitumor agent A sugar-cholestanol compound which can be readily synthesized and which exhibits a satisfactory antitumor activity. An anticancer agent containing, as an active ingredient, a cholestanol compound represented by the following formula (1):	06/28/2011
7968117	Externally triggered microcapsules Disclosed are microcapsules comprising a polymer shell enclosing one or more immiscible liquid phases in which a drug or drug precursor are contained in a liquid phase. The microparticles also contain magnetic particles that can be heated by application of an extern...	06/28/2011
7964214	Method and composition for hyperthermally treating cells in the eye with simultaneous imaging A method and composition for hyperthermally treating cells in the eye with simultaneous imaging. The heat (temperature) production inside the eye (target) tissue is imaged. The desired temperature is achieved using a laser and photoacoustic imaging technique. Hypert...	06/21/2011
7955618	Composition for treatment of inflammatory disorders A pharmaceutical composition for parenteral administration, comprising liposomes composed of non-charged vesicle-forming lipids, including up to 20 mole percent of an amphipathic vesicle-forming lipid derivatized with polyethyleneglycol, and optionally including not...	06/07/2011
7951396	Preparation of nanoliposome-encapsulating proteins and protein-encapsulated nanoliposome Preparing a nanoliposome for encapsulating a protein includes preparing a dispersion by dispersing a phospholipid in an aqueous solution containing the protein, applying a shearing force to the dispersion; adding an additional amount of the phospholipid to the resul...	05/31/2011
7927622	Methods of transnasal transport/immunization with highly adaptable carriers The invention deals with the transport of preferably large molecules across nasal mucosa by means of specially designed, highly adaptable carriers loaded with said molecules. One of the purposes of making such formulations is to achieve non-invasive systemic deliver...	04/19/2011
7919113	Dispersible concentrate lipospheres for delivery of active agents A formulation containing one or more lipophilic agents, methods of making and using the formulation are described herein. The formulation is formed by adding a pre-suspension concentrate composition to an aqueous medium. Upon contact with the aqueous medium, a solid...	04/05/2011
7914814	Topical delivery of arginine of cause beneficial effects A preparation is disclosed for producing enhanced blood flow in tissue thus causing beneficial effects such as promoting hair growth on scalp tissue lacking sufficient hair, restoring normal sexual function in males with erectile dysfunction. Specifically, this is a...	03/29/2011
7914815	Method for delivery of pharmaceuticals for treating or preventing presbyopia Embodiments of the present invention relate to a method for delivering pharmaceuticals to the lens of the eye to treat or prevent presbyopia. According to the embodiments, pharmaceuticals may be applied by providing the pharmaceuticals to the eye and promoting deliv...	03/29/2011
7906139	Compositions and methods of using lamellar bodies for therapeutic purposes Compositions comprising lamellar bodies for removal of extra and intra-vascular fibrin for therapeutic purposes are disclosed. These lamellar compositions are also useful in surgical procedures wherein formation of post-surgical adhesions are likely. Methods of prev...	03/15/2011
7906140	Compositions for mucosal delivery of agents Compositions and methods for mucosal delivery of agents are provided. The compositions are intended for administration to mucosal surface, such as oral and nasal mucosa. The compositions provided contain one or more mucoadhesive proteins and an agent to be delivered...	03/15/2011
7901708	Liposomal apparatus and manufacturing methods The present invention provides apparatus and processes for producing liposomes. By providing a buffer solution in a first reservoir, and a lipid solution in a second reservoir, continuously diluting the lipid solution with the buffer solution in a mixing chamber pro...	03/08/2011
7901709	Temperature-sensitive liposomal formulation A liposome contains an active agent and has a gel-phase lipid bilayer membrane comprising phospholipid and a surface active agent. The phospholipids are the primary lipid source for the lipid bilayer membrane and the surface active agent is contained in the bilayer ...	03/08/2011
7887836	Compositions and methods for treating lymphoma This invention provides methods for treating neoplasias in a mammal. In particular, the invention provides methods for treating various types of lymphomas, including relapsed forms of non-Hodgkin's Lymphoma. These methods involve the administration of liposome-encap...	02/15/2011
7887833	Amphiphilic compounds and vesicles liposomes for organ-specified drug targeting An amphiphilic compound is provided capable of forming vesicles or liposomes, said amphiphilic compound having at least one headgroup containing a selectively cleavable group or moiety such as a residue of a choline or phenylalanine derivative, and at least one hydr...	02/15/2011
7887834	Aqueous dispersions of silicone polyether block copolymers Aqueous dispersions of (AB)n silicone polyether block copolymers, methods for preparing the dispersion compositions, and personal, household, and healthcare formulations containing the compositions are disclosed. The aqueous dispersions can be either vesi...	02/15/2011
7887835	Compound comprising a fluorine-substituted alkyl group and a liposome contrast medium comprising the compound A steroid ester compound of a terminally-fluorinated alkyl fatty acid, a steroid compound having bis(trifluoromethyl)phenyl group, a phosphatidylserine compound having a terminally-fluorinated alkyl group, a glyceride compound having bis(trifluoromethyl phenyl group...	02/15/2011

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Class 424/450 - Liposomes