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Class 424/45 - Organic pressurized fluid


Subclass of Class 424 - Drug, bio-affecting and body treating compositions
Definition: Compositions in which the pressurized fluid is an organic
No. of patents: 1641
Last issue date: 05/29/2012


1                      
NumberTitleIssue Date
8187574Intermittent injection aerosol product for skin
The present invention is directed to an intermittent aerosol dispensing device, for application of a product to skin of a human being, where the aerosol dispensing device includes an intermittent injection mechanism located downstream of an aerosol valve of an aeros...
05/29/2012
8182791Formulations for use in inhaler devices
A formulation for an inhaler device comprises carrier particles having a diameter of at least 50 μm and a mass median diameter of at least 175 μm; active particles; and additive material to which is able to promote release of the active particles from the carrier ...
05/22/2012
8178078Compositions containing a solvated active agent suitable for dispensing as a compressed gas aerosol
A composition for solvating one or more active agents in an aqueous solution which is suitable for dispensing as a compressed gas aerosol composition is disclosed. The composition includes at least one surfactant, at least one active agent (such as a fragrance or an...
05/15/2012
8173107Delivery of antipsychotics through an inhalation route
The present invention relates to the delivery of antipsychotics through an inhalation route. Specifically, it relates to aerosols containing antipsychotics that are used in inhalation therapy. In a method aspect of the present invention, an antipsychotic is delivere...
05/08/2012
8158109Foamable suspension gel
The present subject matter provides foamable suspension gels that foam after release from a container. The foamable suspension gels contain at least one pharmaceutically active agent that is sparingly soluble to insoluble in water, a second pharmaceutically active a...
04/17/2012
8142763Pressurized metered dose inhalers (MDI) containing a solution comprising ipratropium bromide, HFA propellant, and co-solvent and comprising a container with a specific internal surface composition and/or lining
The invention relates to pressurized metered dose inhalers (MDIs) in which all or part of the internal surface is stainless steel, anodized aluminum, or lined with an inert organic coating and which contain a formulation which comprises ipratropium bromide. ...
03/27/2012
8124057Propellant-based nanoparticulate dry powder aerosols and method of making
There invention discloses aqueous dispersions of nanoparticulate aerosol formulations, dry powder nanoparticulate aerosol formulation, propellant-based aerosol formulations, methods of using the formulations in aerosol delivery devices, and methods of making such fo...
02/28/2012
8119105Aerosol container and a method for storage and administration of a pre-determined amount of a pharmaceutically active aerosol
The invention relates to an aerosol container for pharmaceutically active aerosols that are to be administered in predetermined amounts and that are supplied in the container in the form of a suspension, the suspension also comprising, in addition to a pharmaceutica...
02/21/2012
8119106Foamable iodine compositions
The present invention is related to a foamable composition of matter comprising iodine, water, a foam adjuvant, a surface-active agent and a gelling agent. This foamable composition, which may be provided in a propellant free foaming device, or alternatively may fur...
02/21/2012
8114385Oleaginous pharmaceutical and cosmetic foam
The invention relates to stable oleaginous cosmetic or therapeutic foam compositions containing certain active agents, having unique therapeutic properties and methods of treatment using such compositions. The foamable composition includes a polyethylene glycol (PEG...
02/14/2012
8088362Salmeterol superfine formulation
The present invention relates to a pharmaceutical formulation for use in the administration of a long-acting β2-agonist by inhalation. In particular this invention relates to a chemically stable, highly efficient salmeterol HFA solution formulation to be...
01/03/2012
8071073Compositions comprising azelastine and methods of use thereof
The present invention provides pharmaceutical compositions comprising azelastine, or a pharmaceutically acceptable salt or ester thereof including azelastine hydrochloride, and optionally one or more additional active agents. Preferred such compositions further comp...
12/06/2011
8062626Stable pharmaceutical budesonide preparation for producing propellant-free aerosols
The invention relates to ethanol-containing pharmaceutical preparations for the production of propellant-free aerosols. ...
11/22/2011
8062627Methods and compositions for treating pulmonary disorders using optically pure (R,R)-formoterol
A method and composition are disclosed utilizing the pure (R,R) isomer of formoterol, which is a potent bronchodilator with reduced adverse effects, a low incidence of the development of tolerance and an increased duration of action, as compared to racemic formotero...
11/22/2011
8029768Treatment of respiratory diseases
A pharmaceutical composition for pulmonary delivery comprises glycopyrrolate in a controlled release formulation, wherein, on administration, the glycopyrrolate exerts its pharmacological effect over a period greater than 12 hours. ...
10/04/2011
8021649Continuous spray scalp therapy and dispensing systems for same
A spray delivery system in combination with a scalp medication is provided which includes a portable container having a gas imperious container wall, a pressure source disposed within the container, and a selectively operable valve assembly affixed to the container....
09/20/2011
8003080Delivery of drug amines through an inhalation route
The present invention relates to the delivery of drug amines through an inhalation route. Specifically, it relates to aerosols containing drug amines that are used in inhalation therapy. In one aspect of the present invention, a method of delivering an amine drug in...
08/23/2011
8003081Method for improvement of tolerance for therapeutically effective agents delivered by inhalation
A method for improvement of tolerance for therapeutically effective agents delivered by inhalation comprising a pretreatment of a patient with a nebulized lidocaine or a lidocaine-like compound administered immediately or up to about thirty minutes before administra...
08/23/2011
7998463Targeted delivery of lidocaine and other local anesthetics and a method for treatment of cough, asthma and tussive attacks
An anti-tussive nebulized solution for targeted delivery of lidocaine into conducting and central airways. A method for treatment of cough and tussive attacks or episodes using said lidocaine solution. A nebulized lidocaine solution administered in daily dose from a...
08/16/2011
7988952Delivery of drug esters through an inhalation route
The present invention relates to the delivery of drug esters through an inhalation route. Specifically, it relates to aerosols containing drug esters that are used in inhalation therapy. In a method aspect of the present invention, a drug ester is delivered to a pat...
08/02/2011
7947257Method of intranasal administration of granisetron
Compositions are provided for the intranasal administration of granisetron or a pharmaceutically acceptable salt thereof. Preferred compositions are in the form of an aqueous solution. Optionally, the compositions comprise chitosan, a salt or derivative thereof or a...
05/24/2011
7914770Formulation for a metered dose inhaler using hydro-fluoro-alkanes as propellants
An improved suspension formulation for use in a metered-dose inhaler having a hydro-fluoro-alkane propellant is described, the improvement being the controlled addition of a small quantity of water. ...
03/29/2011
7842283Generation of therapeutic microfoam
A method for producing a microfoam suitable for use in scleropathy of blood vessels comprises introducing a physiologically acceptable blood-dispersible gas into a container (1) holding an aqueous sclerosant liquid and releasing the mixture of blood-dispersib...
11/30/2010
7842282Generation of therapeutic microfoam
A method for producing a microfoam suitable for use in scleropathy of blood vessels comprises introducing a physiologically acceptable blood-dispersible gas into a container (1) holding an aqueous sclerosant liquid and releasing the mixture of blood-dispersib...
11/30/2010
7820145Oleaginous pharmaceutical and cosmetic foam
The invention relates to stable oleaginous cosmetic or therapeutic foam compositions containing certain active agents, having unique therapeutic properties and methods of treatment using such compositions. The foamable composition includes at least one solvent selec...
10/26/2010
7749488Pharmaceutical foam
The present invention provides various pharmaceutically active topical delivery compositions. In particular, compositions of the present invention are present in a pressurized container comprising a quick-breaking alcoholic foaming agent, such that when the composit...
07/06/2010
7744855Method of making particles for use in a pharmaceutical composition
A method for making composite excipient particles for use in a pharmaceutical composition comprises a milling step in which particles of an excipient material are milled in the presence of an additive material. The product particles are of small size and the milling...
06/29/2010
7736626HFA supension formulations containing an anticholinergic
The invention relates to propellant gas formulations containing suspensions of the crystalline monohydrate of (1α,2β,4β,5α,7β)-7-[(hydroxydi-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane-bromide. ...
06/15/2010
7736627HFA suspension formulations containing an anticholinergic
The invention relates to propellant gas formulations containing suspensions of the crystalline monohydrate of (1α,2β,4β,5α,7β)-7-[(hydroxydi-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane-bromide. ...
06/15/2010
7718162Medicinal aerosol compositions with a functionalized polyethyleneglycol excipient
The invention comprises a medicinal aerosol composition comprising a propellant, an excipient comprising a functionalized polyethyleneglycol, and a drug. The invention also comprises particulate medicinal compositions comprising particles with a mean mass aerodynami...
05/18/2010
7708980Nonflammable propellant blend
Propellants comprising a combination of: (a) a liquid component that is soluble in the organic chemical-based material; (b) a soluble gas component that has a solubility of at least about 3% by weight in the organic chemical-based material; and, (c) a substantially ...
05/04/2010
7687054Biocompatible compounds for sustained release pharmaceutical drug delivery systems
Methods, compounds, and medicinal formulations utilizing biocompatible polymers for delivery of a drug, particularly for solubilizing, stabilizing and/or providing sustained release of drug from topical, implantable, and inhalation systems. Many of the methods, comp...
03/30/2010
7645442Rapid-heating drug delivery article and method of use
A device, method, and system for producing a condensation aerosol are disclosed. The device includes a chamber having an upstream opening and a downstream opening which allow gas to flow through the chamber, and a heat-conductive substrate located at a position betw...
01/12/2010
7638115Methods and compositions for the introduction of molecules into cells
The present invention is directed to the introduction of molecules, including nucleic acids, carbohydrates, plant growth regulators and peptides into cells and tissues. The present invention is also directed to media and methods for enhancing embryogenic callus prod...
12/29/2009
7638114Method for disinfecting the air
The invention relates to a method for disinfecting the air, comprising the distribution or atomization of a special antimicrobial composition. The invention also relates to antimicrobial compositions and the use thereof in order to disinfect the air. ...
12/29/2009
7611694Aerosol formulation for inhalation comprising an anticholinergic
The present invention relates to a propellant-free, aqueous aerosol formulation for anticholinergics of formula 1 wherein X− denotes an anion. ...
11/03/2009
7601337Delivery of antipsychotics through an inhalation route
The present invention relates to the delivery of antipsychotics through an inhalation route. Specifically, it relates to aerosols containing antipsychotics that are used in inhalation therapy. In a method aspect of the present invention, an antipsychotic is delivere...
10/13/2009
7585493Thin-film drug delivery article and method of use
An article for use in an aerosol device, for producing an aerosol of a drug composition is disclosed. The article includes a heat-conductive substrate having a surface with a selected surface area, and a drug composition film on the substrate surface having a select...
09/08/2009
7566445Medicinal aerosols and methods of delivery thereof
This invention provides a medicinal aerosol formulation comprising a particulate medicament, a fluorocarbon propellant and 6% to 25% w/w of the total formulation of a polar co-solvent, wherein the aerosol formulation is free of surfactant. This invention also provid...
07/28/2009
7556798Highly efficient delivery of a large therapeutic mass aerosol
A method for delivering an agent to the pulmonary system, in a single, breath-activated step or a single breath, comprises administering from a receptacle enclosing a mass of particles, to a subject's respiratory tract, particles which have a tap density of less tha...
07/07/2009
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