Did You Know...
...that the inventor of the electric motor was a blacksmith named Thomas Davenport? Described as "a brilliantly unsuccessful inventor", Davenport invented the first rotary electric motor. In 1836 he headed out -- on foot -- from his Vermont home to file a patent application at the Patent Office in Washington, D.C. By the time he got there, he had squandered away his money and couldn't afford the $30 filing fee so he turned around and went home. When he later mailed in his application with money he'd raised, the Patent office was destroyed in a fire. He did finally get credit for his invention on Feb. 5, 1837.
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| Number | Title | Issue Date |
| 6146653 | Pharmaceutical preparation and a method for the treatment of diabetes A method of treatment of humans suffering from diabetes which involves transplantation into the human of viable porcine islets capable of producing insulin within its host. The invention also includes the particular preparation for such transplantation an... | 11/14/2000 |
| 6143330 | Compositions for inhibiting dental caries and/or middle ear infections and uses thereof Compositions for treating or preventing dental caries and/or middle ear infections. These compositions comprise antibodies to dental caries and/or antibodies to bacteria causing middles ear infections and/or an agent preventing the adhesion, accumulation ... | 11/07/2000 |
| 6139861 | Intraoral topical anti-inflammatory treatment for relief of migraine, tension-type headache, post-traumatic headache facial pain, and cervical-muscle spasm An anti-inflammatory, either a NSAID or glucocorticoid steroid in the form of an ointment, cream, lotion, gel, powder, paste, film, tape or adhesive bandage, provided with appropriate vehicle to allow specific adherence to a specific gingival area is appl... | 10/31/2000 |
| 6132757 | Treatment of sexual dysfunction in certain patient groups Methods for treating specific patient groups for sexual dysfunction are provided. The methods of the present invention comprise the utilization of flosequinan and pharmaceutical compositions comprising flosequinan in patients who are free of cardiac disea... | 10/17/2000 |
| 6123965 | Methods and compositions for enhancing the bioadhesive properties of polymers Methods and compositions are provided for enhancing the bioadhesive properties of polymers used in drug delivery devices. The bioadhesive properties of a polymer are enhanced by incorporating a metal compound into the polymer to enhance the ability of the... | 09/26/2000 |
| 6123957 | Delivery of agents and method for regeneration of periodontal tissues The invention relates to a method of treating periodontal disease and related disorders to regenerate lost tissues, which includes the steps of: combining at least one tissue regenerative agent with at least one cellular recognition agent to form a therap... | 09/26/2000 |
| 6117446 | Drug dosage unit for buccal administration of steroidal active agents A buccal dosage unit is provided for administering a combination of steroidal active agents to a female individual. The novel buccal drug delivery systems may be used in female hormone replacement therapy, in female contraception, to treat female sexual d... | 09/12/2000 |
| 6117445 | Methods for the prevention and treatment of fibrosis and sclerosis Methods of treating or preventing fibrosis and sclerosis by the administration of compositions containing A1 adenosine receptor antagonists and/or P2X purinoceptor antagonists, or combinations thereof.... | 09/12/2000 |
| 6113920 | Pharmaceutical compositions A pharmaceutical composition and a method of inhibiting human immunodeficiency virus (HIV) is disclosed which comprises administering to an HIV infected patient a homogenous combination of lamivudine, zidovudine and a pharmaceutical glidant in an amount w... | 09/05/2000 |
| 6110486 | Buccal polar spray or capsule A buccal aerosol spray or capsule using a polar solvent has now been developed which provides biologically active compounds for rapid absorption through the oral mucosa, resulting in fast onset of effect. The buccal aerosol spray of the invention comprise... | 08/29/2000 |
| 6106286 | Method and device for administering medicine to the periodontium A dental loop for delivering Coenzyme Q10 to the periodontium by direct physical contact therewith, and a method using such loop. The loop is a loop of plain gut defining a series of pockets for carrying a medicament. Coenzyme Q10 is placed within the poc... | 08/22/2000 |
| 6103260 | Simethicone/anhydrous calcium phosphate compositions The invention relates to antifoam oral solid dosage form preparations formed from a free flowing granular composition comprising an admixture of simethicone and either one or both of granular anhydrous tribasic calcium phosphate or dibasic calcium phospha... | 08/15/2000 |
| 6090402 | Oral cleansing: methods and compositions The invention relates to edible oral cleansing and sanitizing compositions and the use of these compositions for reducing plaque and calculus deposition in the mouth and improving oral cleanliness and tooth smoothness. The active ingredients include surfa... | 07/18/2000 |
| 6083525 | Compositions for freshening nostrils and sinus cavities A composition for freshening sinus cavities including a carrier for a masking agent that conceals and eliminates odors emanating from the sinus cavities, and further including an anti-septic or anti-infective constituent. The composition may further inclu... | 07/04/2000 |
| 6083531 | Fast disintegrating oral dosage form The present invention relates to a solid pharmaceutical dosage form for oral administration, consisting essentially of (a) at least one active substance, (b) at least one filler, (c) at least one binding agent, and (d) optionally usual auxiliaries, which dosage for... | 07/04/2000 |
| 6071528 | Adhesive antimicrobial and/or reparative dentin stimulating dental compositions and methods for forming and using such compositions Adhesive antimicrobial dental compositions and methods for forming and using compositions are disclosed. The compositions are primarily useful as pulp caps and dentin liners. The composition includes an alkyl methacrylate having an oxyphosphorus group, a ... | 06/06/2000 |
| 6068851 | Formulation for use in the prevention of pathogen induced diseases including HIV and HSV This invention relates to formulations comprising film-forming components capable of forming per se a physical barrier to pathogens. Thermoreversible gels such as poloxamers are particularly preferred for that use. The film-forming formulations may furthe... | 05/30/2000 |
| 6069188 | Denture stabilizing compositions This invention relates to a denture adhesive composition comprising a lower alkyl vinyl ether-maleic acid, anhydride, or salt polymer or mixtures thereof, one or more metallic salts, nonionically associated with the lower alkyl vinyl ether-maleic acid, an... | 05/30/2000 |
| 6063404 | Bioadhesive tablet This invention relates to a bioadhesive tablet containing at least one bioadhesive adjuvant and at least one lubricant, with at least one surface of the tablet comprising concentric or parallel, straight and/or curved depressions, and to a method for prod... | 05/16/2000 |
| 6060077 | Unit galenical formulation for local hormonotherapy of vaginal dryness A galenical formulation is intended for local, essentially non systemic, treatment of vaginal dryness, in particular in the menopausal woman. It comprises a free natural estrogen, in particular a micronized or vectorized estrogen, selected from 17ଲ-... | 05/09/2000 |
| 6054119 | Preparation used in dental care A preparation used in dental care to protect the teeth, which preparation is anhydrous, with the possible exception of crystal water, and by structure, for example a powder, solid tablet or other anhydrous compositions. The preparation contains a reminera... | 04/25/2000 |
| 6051558 | Compositions suitable for controlled release of the hormone GnRH and its analogs A liquid composition for the controlled release of gonodotropin releasing hormone (GnRH) or its analogs is provided that includes: (i) a non-polymeric, non-water soluble liquid carrier material (HVLCM) of viscosity of at least 5,000 cP at 37° C. that doe... | 04/18/2000 |
| 6045811 | Delivery system for an oral care substance using a permanently deformable strip of material A delivery system for an oral care substance includes a strip of material having a yield point and thickness such that the strip of material substantially conforms to a shape of a tooth and its adjoining soft tissue via permanent deformation under a press... | 04/04/2000 |
| 6039969 | Immune response modifier compounds for treatment of TH2 mediated and related diseases Immune response modifier compounds--imidazoquinoline amines, imidazopyridine amines, 6,7-fused cycloalkylimidazopyridine amines, and 1,2-bridged imidazoquinoline amines--are useful for the treatment of TH2 mediated diseases by administering a therapeutica... | 03/21/2000 |
| 6024981 | Rapidly dissolving robust dosage form The invention is directed to a hard tablet that can be stored, packaged and processed in bulk. Yet the tablet dissolves rapidly in the mouth of the patient with a minimum of grit. The tablet is created from an active ingredient mixed into a matrix of a no... | 02/15/2000 |
| 6019994 | Use of levobupivacaine in treating migraine Levobupivacaine or ropavicaine is used to treat migraine.... | 02/01/2000 |
| 6010719 | Freeze-dried disintegrating tablets Freeze-dried disintegrating tablets, said tablets containing at least a therapeutic agent, a matrix forming agent and a binding agent, in which the tablets contain more than 20% by weight of a matrix forming agent selected from the group consisting of mal... | 01/04/2000 |
| 6004575 | Use of (meth) acrylic acid/maleic acid copolymers for improving mucosal permeability (Meth)acrylic acid/maleic acid copolymers for improving mucosal permeability and pharmaceutical compositions containing them are described.... | 12/21/1999 |
| 6004538 | Oral compositions An oral composition in the form of a toothpaste, powder, liquid dentifrice, mouthwash, denture cleaner, chewing gum, or candy comprising one or more oral composition components selected from abrasives, binders, humectants, surfactants, fluoride ion source... | 12/21/1999 |
| 6004573 | Biodegradable low molecular weight triblock poly(lactide-co-glycolide) polyethylene glycol copolymers having reverse thermal gelation properties A water soluble biodegradable ABA-type block copolymer made up of a major amount of hydrophobic poly(lactide-co-glycolide) copolymer A-blocks and a minor amount of a hydrophilic polyethylene glycol polymer B-block, having an overall average molecular weig... | 12/21/1999 |
| 5998431 | Sustained-release matrices for dental application A sustained-release matrix for dental application includes either an anti-microbial agent or a colorant that is released from the matrix when the matrix contacts water. The preferred matrices include a water-soluble polymer and a water-insoluble support r... | 12/07/1999 |
| 5993836 | Topical anesthetic formulation A topical, transdermal anesthetic comprising a eutectic mixture of, preferably, lidocaine and prilocaine in a ratio of about 3:1 by weight, incorporated within a lipophilic base. In addition to the property of rapid-onset, the formulation of the present i... | 11/30/1999 |
| 5993846 | Bioadhesive emulsion preparations for enhanced drug delivery The invention relates to novel methods for making oil-in-water emulsions having mucoadhesive properties which are primarily intended for administration of biologically active compounds to mucosal surfaces. The emulsion has an aqueous continuous phase and ... | 11/30/1999 |
| 5993413 | Intraoral administration device and system An intraoral administration device having an elongated, substantially plate-like arcuate oral screen designed to conform to the teeth and intended to be accommodated in the space between the teeth and the lips. The oral screen includes containers for the ... | 11/30/1999 |
| 5989569 | Delivery system for a tooth whitener using a permanently deformable strip of material A delivery system for an oral care substance includes a strip of material having a yield point and thickness such that the strip of material substantially conforms to a shape of a tooth via permanent deformation under a pressure less than about 250,000 Pa... | 11/23/1999 |
| 5989582 | Administration of ketamine for detoxification and to treat substance addiction, and compositions therefor A method to facilitate detoxification and treat substance addiction by administration of ketamine and a benzodiazepine. A preferred dosage range of ketamine is about 0.01 mg/kg of body weight to about 1 mg/kg. Pharmaceutical compositions comprising this d... | 11/23/1999 |
| 5989535 | Polymeric bioadhesive emulsions and suspensions and methods of treatment Bioadhesive/mucoadhesive composition in a suspension or emulsion form that delivers drugs to the target tissue in a sustained manner is formulated. A composition, method of manufacture and its application in treatment of mammalian tissue are disclosed. Th... | 11/23/1999 |
| 5985313 | Method for decreasing the frequency of transmission of viral infections using cellulose acetate phthalate or hydroxypropyl methylcellulose phthalate excipients A method for decreasing the frequency of transmission of human immunodeficiency virus or herpesviruses by administering to a human an anti-human immunodeficiency virus amount or an anti-herpesvirus amount of cellulose acetate phthalate (CAP) or hydroxypro... | 11/16/1999 |
| 5985320 | Materials and methods for enhancing cellular internalization Compositions and methods for delivering agents across cell membranes are disclosed. The compositions include an agent to be delivered, a viscous material, such as a hydrogel, lipogel or viscous sol, and, optionally, a carrier that includes a ligand that b... | 11/16/1999 |
| 5972374 | Chewing gum with teeth whitener A new chewing gum with teeth whitener for helping whiten and brighten teeth while helping freshen the breath. The inventive device includes an elongate gum member having a central bore extending along its longitudinal axis. Extending through the central b... | 10/26/1999 |
