Did You Know...
...that Charles Goodyear performed some of his experiments on rubber while in debtor's prison? He was there so often he referred to it as his "hotel". Chronically in debt because of poor business sense and ill health, Goodyear depended on the generosity of friends and family. Even after he unlocked the secret to vulcanizing rubber, he was unable to improve his financial situation. When he died, his estate was $200,000 in debt.
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| Number | Title | Issue Date |
| 7993667 | Methods of manufacturing a medicated tampon assembly A method is provided for manufacturing a medicated tampon assembly having a tampon body, the method including applying a formulation including a therapeutic agent to a substrate to produce a plurality of dosage forms; separating one of the dosage forms from the subs... | 08/09/2011 |
| 7442179 | Pre-fill applicator A pre-fill vaginal applicator comprising a tubular barrel having an open end and a dispensing end provided with at least one dispensing opening formed therein. A selectively removable closure, such as a snap cap or threaded cap, closes the dispensing end of the barr... | 10/28/2008 |
| 7348023 | Absorbent articles containing additives Absorbent articles containing an additive are disclosed. The absorbent articles include an effective amount of an inhibitory compound, such as thiolactomycin or thiomalonate, to substantially inhibit the production of TSST-1 by Gram positive bacteria. ... | 03/25/2008 |
| 7344732 | Medicated tampon A tampon adapted to deliver a therapeutic agent, the tampon including a tampon body that is manufactured at a first manufacturing facility; and a dosage form coupled to the body, wherein the dosage form includes a formulation including a therapeutic agent, and where... | 03/18/2008 |
| 7341737 | Medicated tampon A tampon adapted to deliver a therapeutic agent, the tampon including a tampon body having a distal end; and a dosage form affixed to the distal end of the tampon body, wherein the dosage form includes a formulation including a therapeutic agent, and wherein the dos... | 03/11/2008 |
| 7338956 | Acylamino-substituted heteroaromatic compounds and their use as pharmaceuticals The present invention relates to acylamino-substituted heteroaromatic compounds of formula I, wherein R1, R2, R3, R4 and R5 and X are as defined herein, to pharmaceutic... | 03/04/2008 |
| 7323186 | Non-absorbent articles containing additives Non-absorbent articles, such as tampon applicators, containing an additive are disclosed. The non-absorbent articles include an effective amount of an inhibitory compound, such as thiolactomycin or thiomalonate, for example, to substantially inhibit the production o... | 01/29/2008 |
| 7320801 | Patch for treating symptoms of a skin abscess A patch, or bandage for treating skin infections has a backing with pressure-sensitive adhesive for securing on a user's skin in the area of the boil. A liquid absorbent member is positioned in the center of the patch, while a carrier with a medicinal formulation, c... | 01/22/2008 |
| 7312067 | Lactic acid producing bacteria for use as probiotic organisms in the human vagina The present invention discloses novel isolated strains of lactic acid producing bacteria of the genera Lactobacillus and Pediococcus, and a method for isolation of such bacterial strains, having the ability to colonise and become established in a human... | 12/25/2007 |
| 7258867 | Aromatic compositions as inhibitors of exoprotein production in non-absorbent articles Non-absorbent articles are disclosed. The non-absorbent articles include an effective amount of an aromatic inhibitory compound to substantially inhibit the production of exotoxins by Gram positive bacteria. The aromatic inhibitory compounds of the present invention... | 08/21/2007 |
| 7235263 | Processes for controlling microbial organic compound production Processes for preparing products comprising an oxygen-generating additive for reducing the amount of skin irritation and inflamation and odor are disclosed. Specifically, products such as training pants and diapers are disclosed which contain a carbohydrate-hydrogen... | 06/26/2007 |
| 7138559 | pH reducing formulation and delivery system for a tampon A formulation effective in reducing the pH in a menstruating vagina or in a tampon inserted therein to below pH 5.5, comprising (a) 3–80% by weight of a solid organic acid polymer; (b) 92–15% by weight of a solid organic acid; and (c) 5–30% of a wetting agent.... | 11/21/2006 |
| 7118759 | Absorbent articles containing additives Effective amounts of the inhibitory compounds described herein capable of significantly reducing the production of TSST-1 are as follows: (1) compounds of Structure (I): from about 0.0001 micromoles/gram absorbent product to about 0.08 micromoles/gram absorbent prod... | 10/10/2006 |
| 7084171 | Compounds and therapies for the prevention of vascular and non-vascular pathologies The invention provides a method of treating a mammal having, or at risk of, an indication associated with a TGF-beta deficiency comprising administering one or more agents that is effective to elevate the level of TGF-beta. The invention also provides novel compound... | 08/01/2006 |
| 7060223 | Polymeric medium for the retention of reagent species for use in a hand-held device for the relatively rapid detection of the presence of an analyte of interest in a sample Disclosed herein is a polymeric sampling swab for obtaining samples of an analyte of interest from solid surfaces or from liquid substances. The polymeric material of which the swab is composed is characterized by a high resistance to chemical and mechanical degrada... | 06/13/2006 |
| 6982091 | Vaginal delivery of chemotherapeutic agents and inhibitors of membrane efflux systems for cancer therapy Devices, methods, and compositions for cancer therapy by administration of chemotherapeutic agents and/or inhibitors of membrane efflux systems to the vagina for topical and systemic tumor targets. ... | 01/03/2006 |
| 6916545 | Resin composition, thermoplastic resin laminate, and production methods thereof A resin composition to be used as a material for a various part of an automotive vehicle. The resin composition comprises a copolymer (A) formed by copolymerization of a first unsaturated monomer (a) and a second mononer (b). The first unsaturated monomer has a func... | 07/12/2005 |
| 6905701 | Formulations for transmucosal vaginal delivery of bisphosphonates Devices, methods, and improved formulation for transmucosal vaginal delivery of bisphosphonates. A targeted site delivery of bisphosphonates to the systemic circulation using a vaginal device comprising an improved bisphosphonate formulation for transmucosal deliver... | 06/14/2005 |
| 6905692 | Topical compositions containing probiotic bacillus bacteria, spores, and extracellular products and uses thereof The present invention discloses compositions derived from an isolated Bacillus species, spores, or an extracellular product of Bacillus coagulans comprising a supernatant or filtrate of a culture of said Bacillus coagulans strain, suitable for t... | 06/14/2005 |
| 6899890 | Bioadhesive drug delivery system The present invention relates to a novel essentially pH neutral vaginal drug delivery system suitable for modified delivery of a therapeutically active material in the vaginal cavity. The vaginal drug delivery system comprises an essentially pH neutral emulsion havi... | 05/31/2005 |
| 6887496 | Products for controlling microbial organic compound production Products comprising an oxygen-generating additive for reducing the amount of skin irritation and inflamation and odor are disclosed. Specifically, products such as training pants and diapers are disclosed which contain a carbohydrate-hydrogen peroxide crystalline po... | 05/03/2005 |
| 6761885 | Strain of Lactobacillus plantarum and uses thereof A novel strain of Lactobacillus plantarum, referred to as LB931, has now been isolated. The strain has been deposited at Deutsche Sammlung von Mikroorganismen, Braunschweig, DE. It has been assigned accession number DSM11918. Accordingly LB931 can be used for... | 07/13/2004 |
| 6702797 | Fibrous articles having odor adsorption ability and method of making same There is provided a fibrous absorbent article for absorbing body fluids. The article includes a fibrous material suitable for absorbing the body fluids, and a molecular sieve disposed within the fibrous material to reduce odors from the body fluids. The m... | 03/09/2004 |
| 6676957 | Non-absorbent substrates for the inhibition of exoprotein production from gram positive bacteria Non-absorbent substrates for use in inhibiting the production of exoproteins from Gram positive bacteria, such as harmful proteins produced by Staphylococcus species, are provided. The substrates are particularly useful for inhibiting the production of TS... | 01/13/2004 |
| 6656913 | Inhibition of exoprotein production from gram positive bacteria A method of inhibiting the production of exoproteins from Gram positive bacteria, such as harmful proteins produced by Staphylococcus species, is described. The method is particularly useful for inhibiting the production of TSST-1, alpha-toxin and/or ente... | 12/02/2003 |
| 6645506 | Topical compositions containing extracellular products of Pseudomonas lindbergii and Emu oil The present invention discloses compositions derived from an isolated Bacillus species, spores, or an extracellular product of Bacillus coagulans comprising a supernatant or filtrate of a culture of said Bacillus coagulans strain, suitable for topical app... | 11/11/2003 |
| 6596297 | Biodegradable microbicidal vaginal barrier device An intravaginal bio-erodible microbicidal barrier device. The device comprises (a) at least one micronized compound selected from the group consisting of cellulose acetate phthalate and hydroxypropylmethylcellulose phthalate, and (b) at least one pectin, ... | 07/22/2003 |
| 6572874 | Vaginal delivery of bisphosphonates Devices, methods, and compositions for vaginal delivery of bisphosphonates. A targeted site delivery of bisphosphonates to the vagina using a medicated intravaginal device comprising a bisphosphonate composition formulated for transvaginal delivery. A met... | 06/03/2003 |
| 6572875 | Biodegradable microbicidal vaginal barrier device An intravaginal bio-erodible microbicidal barrier device. The device comprises (a) at least one micronized compound selected from the group consisting of cellulose acetate phthalate and hydroxypropylmethylcellulose phthalate, and (b) at least one water so... | 06/03/2003 |
| 6548552 | Absorbent article, particularly a tampon having additives that reduce toxic shock syndrome toxin production An absorbent article, particularly a tampon having additives that reduce toxic shock syndrome toxin (TST-1) production is disclosed. The tampon has a combination of an effective amount of at least one oxygen inhibiting agent and an effective amount of at ... | 04/15/2003 |
| 6537566 | Compositions and methods for the non-invasive treatment of uterine fibroid cells The proliferation of uterine fibroid leiomyoma cells is inhibited by certain Fibroid Cell Growth Inhibitor (FGI) agents. The pharmacological doses of these FGI agents in the milieu of uterine fibroid cells can be made high enough to not only inhibit proli... | 03/25/2003 |
| 6420336 | Methods of using cyanovirins topically to inhibit viral infection The present invention provides antiviral proteins, peptides and conjugates, as well as methods of obtaining these agents. The antiviral proteins, peptides and conjugates of the present invention can be used alone or in combination with other antiviral age... | 07/16/2002 |
| 6416779 | Device and method for intravaginal or transvaginal treatment of fungal, bacterial, viral or parasitic infections Devices, methods, and compositions for treating vaginal fungal, bacterial, viral and parasitic infections by intravaginal or transvaginal administration of therapeutic and/or palliative antifungal, antibacterial, antiviral or parasiticidal drugs to the va... | 07/09/2002 |
| 6403113 | Anti-microbic agent Anti-microbic copolymers and derivatives thereof are used in methods for controlling odor in hygienic articles. The copolymers comprise at least two different ethylenically unsaturated monomers.... | 06/11/2002 |
| 6316019 | Process for adding pharmaceutically active compounds to substrates The present invention relates to a low temperature process for adding pharmaceutically active compounds to substrates. The substrates are preferably those used in the manufacture of disposable absorbent articles, or are the articles themselves. The pharma... | 11/13/2001 |
| 6294188 | Methods involving changing the constitutive and stimulated secretions of the local reproductive system of women The first aspect of the invention relates to a method of inducing changes in the cervical mucus of a person to achieve a contraceptive effect, and wherein the method involves administering to the person an effective amount of ebrotidine sufficient to achi... | 09/25/2001 |
| 6284261 | Disposable absorbent article containing an essential oil The invention relates to disposable absorbent articles containing an additive to control odors associated with bodily fluids. The invention is particularly useful in articles used to manage urine and menstrual fluids. The single additive provides both a p... | 09/04/2001 |
| 6264973 | Apparatus and method for anesthetizing the cervical region of a female A novel and useful apparatus for delivering an anesthetic locally to the cervical region of a female is provided, wherein the apparatus comprises a ring having a surface and at least one depression on the surface. An anesthetic composition comprising an a... | 07/24/2001 |
| 6264972 | Tampon A tampon constructed of a foamed plastic polyvinyl acetal material with an outer skin and a less dense inner central portion having a greater large pore and common pore density. The polyvinyl acetal material is impregnated with glycerine in a range of 2% ... | 07/24/2001 |
| 6258374 | Foam-forming pharmaceutical composition The invention provides a pharmaceutical composition for rectal or vaginal administration which comprises at least two parts wherein the composition comprises (i) two or more physiologically acceptable substances each in separate parts of the composition w... | 07/10/2001 |
