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| Number | Title | Issue Date |
| 5069906 | Intra-vaginal device and method The invention disclosed provides an intra-vaginal device prepared using ingredients which slowly release in the vagina over a significant period of time. The present intra-vaginal device also usefully serves as a drug release means for controllably releas... | 12/03/1991 |
| 5061738 | Blood compatible, lubricious article and composition and method therefor A leach resistant composition includes a quaternary ammonium complex of heparin and a silicone. A method for applying a coating of the composition to a surface of a medical article is within the purview of the present invention. Medical articles having su... | 10/29/1991 |
| 5061487 | Antimicrobial superabsorbent compositions and methods An antimicrobial superabsorbent composition of a cross-linked hydrophilic sodium salt form of a partially neutralized acrylic acid-based polymer gel having covalently bonded thereto a silane. The composition can be in the form of flakes, strips, powders, ... | 10/29/1991 |
| 5035884 | Methylene pyrrolidone copolymers for contact lens and pharmaceutical preparations A new series of copolymers which are useful as coatings for solid dosage forms, for transdermal devices, for wound dressing materials, and for contact lenses. Also disclosed are methods for preparing monomers and polymers as well as pharmaceutical composi... | 07/30/1991 |
| 5015666 | Triarylcyclopropanes as antiestrogens and antitumor agents Triarylcyclopropane derivatives in which one or more of the aryl groups includes a hydroxy as a substituted or unsubstituted or alkoxy or side chain substituent. The compounds are useful as antiestrogens and anti-tumor agents.... | 05/14/1991 |
| 5015474 | Composition for imparting moisture to a substrate Methods and compositions are provided for alleviating the dryness of a dermal or mucosal membrane substrate. The compositions are formulated from eriodictyon fluid which is a Yerba Santa extract and viscous excipients, and may be in the form of an aqueous... | 05/14/1991 |
| 5004694 | Complement-dependent cytolytic anti-Trichomonas vaginalis monoclonal antibodies Novel monoclonal antibodies specific to Trichomonas vaginalis, having complement--fixing ability and lysing Trichomonas vaginalis in the presence of complement are disclosed and may be used in therapy and diagnosis of trichomoniasis. Hybridomas producing ... | 04/02/1991 |
| 4997653 | Method for treating endometriosis with topical preparations containing danazol A topical preparation of danazol comprising a matrix base, danazol retained therein, and optionally a release-promoting agent is provided. The topical preparation is more effective than oral administration of danazol in the shrinkage of endometriosis tissue, t... | 03/05/1991 |
| 4983393 | Intra-vaginal device and method for sustained drug release The invention disclosed provides an intra-vaginal device prepared using ingredients which slowly release in the vagina over a significant period of time. The present intra-vaginal device also usefully serves as a drug release means for controllably releas... | 01/08/1991 |
| 4981686 | Personal lubricant A personal lubricant which is not contraceptive, does not impede sperm motility and may contain healing ingredients.... | 01/01/1991 |
| 4961931 | Method for the management of hyperplasia The invention is for a vaginal dispenser comprising a wall surrounding an internal lumen and having a pair of ends with one end placed inside the other end to form a closed dispenser. A vaginally administrable beneficial agent is housed in the lumen for r... | 10/09/1990 |
| 4959216 | Contraceptive methods and delivery systems thereof A contraceptive method for living animals (including human beings) can utilize a polyurethane or polyvinylacetate (PVA) disc as an inert carrier for contraceptive preparations, the disc being implanted before intercourse to engage the external os of the c... | 09/25/1990 |
| 4879315 | Cyclopropyl analogs as anti-estrogenic, anti-tumor and female fertility agents Anti-estrogenic cyclopropyl analogs such as 1,1-dichlorocis-2,3-diphenylcyclopropane, when administered to a subject function as anti-tumor agents to prevent the development of estrogen-dependent tumors in the subject and substantially arrest the gro... | 11/07/1989 |
| 4874612 | Multi-component long-acting medicament formulation for implantation Multi-component implants which contain at least two shaped pieces containing active compound, wherein these shaped pieces contain biologically degradable copolymers of lactic acid and glycolic acid with a ratio by weight of lactide to glycolide of 90:10 t... | 10/17/1989 |
| 4873087 | Suppository preparation having excellent absorption property A preparation containing an absorption promoter selected from N-acyl amino acid derivatives or N-acyl peptide derivatives represented by the formula: R-CO-A (R is an aliphatic hydrocarbon group, an aromatic hydrocarbon group or an aryl-substituted lower h... | 10/10/1989 |
| 4871543 | Intravaginal devices The invention concerns an intravaginal device comprising a combination of 17 ଲ-estradiol and a supporting matrix for treating hypoestrogenic women. The device releases continuously 17 ଲ-estradiol at a rate of about 0.5 to about 25 μg/24 h. Th... | 10/03/1989 |
| 4837111 | Dosage form for dispensing drug for human therapy An osmotic dosage system is disclosed for delivering the therapeutically beneficial drug doxazosin to an environment of use over time.... | 06/06/1989 |
| 4822616 | Vaginal ring A vaginal ring comprises a supporting ring 1 free of active agent. A layer 2, which contains an active agent such as a steroid, is applied on its outer rim, optionally in a continuous groove provided in the supporting ring. This layer, in turn, is coated ... | 04/18/1989 |
| 4816257 | Method for producing an in vivo environment suitable for human embryo transfer A method for producing, in a functionally agonadal human female body, an environment suitable for the implantation, nutrition, and development of an embryo, comprising the placement of at least one carrier containing at least one releasable steroid hormon... | 03/28/1989 |
| 4801444 | Medicinal preparation for individual prevention of venereal diseases and treatment of urogenital trichomoniasis A medicinal preparation for individual prevention of venereal diseases and treatment of urogenital trichomoniasis comprises an efficient quantity of an active principle which is essentially a synergistic mixture of para-nitro-alpha-chlorocinnamic aldehyde... | 01/31/1989 |
| 4788060 | Multiple electrolyte douche and wipe composition A disposable feminine hygiene kit and system that includes a douche composition for internal cleansing of the vagina, and a wipe solution for external cleansing of the vulva. The douche formulation may be a ready-to-use liquid solution, or a concentrate. ... | 11/29/1988 |
| 4786500 | Programmable agent delivery system This invention pertains to a programmable delivery system.... | 11/22/1988 |
| 4762717 | Continuous delivery of luteinizing hormone releasing hormone compositions in combination with sex steroid delivery for use as a contraceptive This invention is directed to a delivery system and a method useful for preventing pregnancy in female mammals by administering an LHRH composition. The method comprises administering during the entire follicular phase of the menstrual cycle, beginning at... | 08/09/1988 |
| 4722936 | Deodorization vaginal products and catamenials A method of prophylactics with respect to deodorization by ascorbic acid, salts and esters, topically applied by means of carriers which are otherwise regularly employed in the vaginal area, such as a pharmacological appliance including gauze pads, an abs... | 02/02/1988 |
| 4722937 | Antitoxin vaginal products and catamenials A method of prophylactics with respect to detoxification of Staphylococcus aureus and other toxins by ascorbic acid, salts and esters, topically applied by means of carriers which are otherwise regularly employed in the area where Staphylococcus aureus or... | 02/02/1988 |
| 4693705 | Vaginal contraceptive system The invention features an innovative vaginal sponge contraceptive device that has active spermicide. The active spermicide allows the device to be used instantly upon removal from its sealed packet. The sponge is of a sufficient size such that swelling ag... | 09/15/1987 |
| 4692143 | Unit package containing ready-to-use vaginal contraceptive A premoistened ready-for-use vaginal contraceptive device and method of use thereof are described wherein a porous polyurethane sponge is provided which is impregnated with a bacteria-free sterile spermicide, pectin and pH control and swelling agent aqueo... | 09/08/1987 |
| 4678463 | Devices for insertion into a body cavity of an animal and/or applicators therefor A device for insertion into a body cavity of an animal and for producing a controlled rate of release of chemicals into the body of the animal, has a spine with a body and legs hinged to the body, the spine being coated with a coating incorporating therei... | 07/07/1987 |
| 4649042 | Rumen delivery device An improved device for delivery of a medicament to the digestive tract of a ruminant animal comprises a polymeric medicated core retained in a dense tube by a relatively thick layer of an elastic sealant.... | 03/10/1987 |
| 4553972 | Disposable intravaginal contraceptive devices releasing 1-substituted imidazoles Devices, of suitable form and size for insertion into the vagina of a female mammal, composed of a polymeric material which has, incorporated in it, a 1-substituted imidazole spermicide and a pharmaceutically acceptable chelating agent, and which release ... | 11/19/1985 |
| 4551148 | Vaginal delivery systems and their methods of preparation and use Systems and their methods of preparation and use that release an active agent in a controlled manner for an extended period in a vaginal cavity environment. The systems are capable of delivering the active agent for periods greater than three hours at a p... | 11/05/1985 |
| 4526578 | Vaginal diaphragm A vaginal diaphragm is disclosed comprising an annular reservoir housing a beneficial agent, and in a preferred embodiment the diaphragm film embraces a means for containing and releasing a beneficial agent.... | 07/02/1985 |
| 4493699 | Contraceptive methods Long chain alkyl and alkenyl sulfonates, sulfates and sulfoalkyl alkanoate salts, administered intravaginally for contraception.... | 01/15/1985 |
| 4475916 | Osmotic drug delivery system An osmotic drug (or other beneficial substance) delivery system comprises a compartment with one or more chambers in series formed by an external shell and chamber-dividing walls of a microporous material and successive overlayers of semipermeable membran... | 10/09/1984 |
| 4462989 | Method and agents for arresting infection A method and associated agents for the arrest of infections resulting from organism growth in contact with an iron-containing body fluid, comprising administering an agent capable of immobilizing the body fluid so that the iron it contains is nutritionall... | 07/31/1984 |
| 4452775 | Cholesterol matrix delivery system for sustained release of macromolecules Delivery systems for releasing macromolecular active agents to a body site at a controlled rate for a prolonged period of time, comprising a cholesteric matrix permeable to passage of the macromolecular active agent by diffusion, are disclosed. The choles... | 06/05/1984 |
| 4449980 | Methods of making intra-vaginal devices and/or intra-vaginal devices An intra-vaginal device for supplying minerals, hormones or medicoments to an animal is formed as an injection moulded polymeric body having a skin in which adjacent at least part of the surface thereof at least one active ingredient is incorporated. The ... | 05/22/1984 |
| 4449983 | Simultaneous delivery of two drugs from unit delivery device An osmotic device is disclosed for delivering two beneficial drugs to an environment of use. The device comprises a wall surrounding a lumen divided into a first compartment containing a drug that is separated by a hydrogel partition from a second compart... | 05/22/1984 |
| 4402693 | Medicated device holder A medicated device comprises a substantially cylindrical, hollow body member having radially outwardly extending annular ridges at each end, a lengthwise slot, and inwardly extending flanges along the edges of the slot which have concave facing surfaces. ... | 09/06/1983 |
| 4391797 | Systems for the controlled release of macromolecules Delivery systems manufactured in the form of polymeric compositions for the controlled delivery of macromolecules to environments of use are disclosed. The systems are characterized as two-phase compositions comprising a phase formed of an insoluble polym... | 07/05/1983 |
