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Patent No. 5970981

Mouthguard made at least partially from an edible candy

A mouthguard includes a U-shaped upper bite plate which removably fits over upper teeth of a person, with the entire upper bite plate being made from a soft, deformable and edible gummi candy.

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Class 424/427 - Ocular


Subclass of Class 424 - Drug, bio-affecting and body treating compositions
Definition: Subject matter in which special physical form is intended
No. of patents: 689
Last issue date: 04/03/2012


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NumberTitleIssue Date
6312706Prepolymers useful in biomedical devices
A novel polyurethane based prepolymer useful in biomedical devices which provides high oxygen permeability and superior physical properties....
11/06/2001
6299895Device and method for treating ophthalmic diseases
A method and device for delivering a biologically active molecule to the eye, either intraocularly or periocularly, and method and device for treating ophthalmic disorders in a patient suffering therefrom....
10/09/2001
6274160Methods of use of histamine H2 agonists in treating dry eye
A topical ophthalmic composition for the treatment of dry eye in humans, comprising one or more histamine H2 agonists, is disclosed....
08/14/2001
6264941Compositions for the delivery of biologically active molecules using genetically altered cells contained in biocompatible immunoisolatory capsules
This invention provides improved devices and methods for long-term, stable expression of a biologically active molecule using a biocompatible capsule containing genetically engineered cells for the effective delivery of biologically active molecules to ef...
07/24/2001
6264935Ophthalmic composition containing a carbonic anhydrase inhibitor and xanthan gum
The present invention relates to ophthalmic compositions for the treatment of ocular hypertension and glaucoma, comprising a hypotonic solution of 0.1 to 0.2% (w/w) of xanthan gum and 0.5 to 5% (w/w) of a topical carbonic anhydrase inhibitor or an ophthal...
07/24/2001
6264971Ocular insert
A flexible ocular insert device adapted for the controlled sustained release of a drug upon insertion into the upper or lower fornix of the eye. The device comprises an elongate body of a polymeric material including two end portions, wherein the body con...
07/24/2001
6261546Methods and compositions for stabilizing acetylcholine compositions
A pharmaceutical product which includes two-chambers, one having a buffered diluent and the other having acetylcholine. Upon mixing the chamber contents, a buffered efficacious acetylcholine product is prepared for post-surgical ophthlamic injection. Anot...
07/17/2001
6258856Method for preventing or controlling cataract
A method for preventing or treating pathological changes which occur in association with cataract formation in the mammalian eye by protecting lens cells against the cataractogenic effects of transforming growth factor-ଲ (TGFଲ). Estrogen or an...
07/10/2001
6248363Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
The present invention provides solid pharmaceutical compositions for improved delivery of a wide variety of pharmaceutical active ingredients contained therein or separately administered. In one embodiment, the solid pharmaceutical composition includes a ...
06/19/2001
6242198Methods of treatment of eye trauma and disorders
Methods are provided for treatment of eye disorders and injury, including methods for treatment of reduced flow of blood or other nutrients to retinal tissue and/or optic nerve, methods for treatment of retinal ischemia and trauma and methods for treatmen...
06/05/2001
6231889Unit dosage forms for the treatment of herpes simplex
The components of this invention are chosen because of their complementarity for the prevention or treatment of diseases caused by the herpes simplex virus. L-Lysine favorably increases the physiologic immunomodulation necessary for defense against this v...
05/15/2001
6221401Bilayer structure which encapsulates multiple containment units and uses thereof
The present invention provides a bilayer structure for encapsulating multiple containment units. These containment units can attach or contain therapeutic or diagnostic agents that can be released through the bilayer structure. A suitable example of such ...
04/24/2001
6217895Method for treating and/or preventing retinal diseases with sustained release corticosteroids
The present invention relates to a method for administering a corticosteroid to a posterior segment of an eye. In the method, a sustained release device is implanted to deliver the corticosteroid to the eye. The aqueous corticosteroid concentration remain...
04/17/2001
6218373Formulations containing hyaluronic acid
A method of treating a disease of condition administering topically to the skin or exposed tissue of a human, a dosage amount of a pharmaceutical composition, said dosage comprising a therapeutically effective amount of a drug to treat said disease or con...
04/17/2001
6217896Conjunctival inserts for topical delivery of medication or lubrication
The present invention provides an improved conjunctival insert for topical delivery of medication or lubrication into the conjunctival spaces and upon the ocular surface of human eye. Specifically, three physical designs are provided, differing by size, n...
04/17/2001
6210706S (+) Desmethylselegiline and its use in therapeutic methods and pharmaceutical compositions
The present invention provides novel compositions and methods for using the S(+) enantiomer of desmethylselegiline (N-methyl-N-(prop-2-ynyl)-2-aminophenylpropane), for the treatment of selegiline-responsive diseases and conditions. Diseases and conditions...
04/03/2001
6207172Composition for the delivery of a pharmaceutical agent to a patient
The present invention relates to a composition for the delivery of a pharmaceutical agent to a patient that comprises polyethylene glycol, an aqueous solution containing polyvinylpyrrolidone, and a pharmaceutical agent. The invention also relates to metho...
03/27/2001
6193957Pharmaceutical compositions for treating late phase allergic reactions and inflammatory diseases
A method of treating a mammalian patient suffering from or prone to a condition characterized by late phase allergic reactions, airway hyperresponsiveness or inflammatory reactions, e.g., asthma, allergic rhinitis, allergic dermatitis, allergic conjunctiv...
02/27/2001
6180687In vivo polymerizable ophthalmic compositions and methods of using
In vivo polymerizable intraocular lens compositions which comprise substituted fluoroalkyl or perfluoroalkyl monomers having anionic, cationic, and/or nonionic surface active functionality in the unsaturated fluorophobic ends. The compositions are prefera...
01/30/2001
6165490Biological material, method of preparing such materials, uses thereof and products made therefrom
A biological material is prepared for use in ophthalmology by steps of providing animal pericardium, subjecting the animal pericardium to multiple steps of freezing and thawing in a salt solution and incubating the animal pericardium in a solution of ammo...
12/26/2000
6153217Nanocochleate formulations, process of preparation and method of delivery of pharmaceutical agents
A process for producing a small-sized, lipid-based cochleate is described. Cochleates are derived from liposomes which are suspended in an aqueous two-phase polymer solution, enabling the differential partitioning of polar molecule based-structure by phas...
11/28/2000
6149931Methods and pharmaceutical compositions for the closure of retinal breaks
Described are compositions, methods, and articles of manufacture for the closure of retinal breaks with a non-toxic polymer. Transformation to a gel-like coat is achieved by photochemical reactivity, chemical reactivity, and by physicochemical response....
11/21/2000
6143315Biochemical contact lens for treating injured corneal tissue
Methods for treating injured corneal tissue are described. The methods include contacting injured corneal tissue with a contact lens which includes an amniotic composition such that scarring of the injured corneal tissue is reduced. Methods for conditioni...
11/07/2000
6136334Medical uses of in situ formed gels
Balanced pH, hyperosmotic, hypoosmotic, or isoosmotic gels are ideal vehicles for drug delivery. They are especially suited for topical body cavity or injection application of drugs or diagnostic agents; for drug or diagnostic agent delivery to the eye of...
10/24/2000
6136793Formulations containing hyaluronic acid
A method of treating a disease or condition comprising administering topically to the skin or exposed tissue of a human, a dosage amount of a pharmaceutical composition, said dosage comprising a therapeutically effective amount of a drug to treat said dis...
10/24/2000
6132751O/W emulsion composition for eye drops
An O/W emulsion composition for eye drops comprises a drug selected from the group consisting of fluorometholone, clobetasone butyrate and clobetasol propionate; a phospholipid; liquid paraffine; and water. The O/W emulsion composition is excellent in sol...
10/17/2000
6132755Transcorneal drug-release system
The invention refers to a transcorneal system for the actively controlled transcorneal delivery of a medicament into a subject comprising an active substance reservoir and a device provided with a plurality of micro-pins or micro-blades adapted in use to ...
10/17/2000
6126957Method of treating disorders of the eye
The present invention relates, in general, to methods of treating disorders of the eye, and, in particular, to methods of preventing or treating elevated eye pressure and glaucoma. The invention further relates to compounds and compositions suitable for u...
10/03/2000
6120484Otological implant for delivery of medicament and method of using same
The present invention is directed to an otological implant for delivery of medicament and a method of using the implant. The implant includes a wick inserted through an aperture in a membrane. One end of the wick is in contact with the treatment site and ...
09/19/2000
6121329Topical administration of 2-amino-2-(2-(4-octylphenyl)ethyl)propane-1,3-diol
An external preparation for topical administration which aims at inhibiting rejection reactions at organ or bone marrow transplantation or treating autoimmune diseases or allergic diseases and contains as the active ingredient 2-amino-2-(2-(4-octylphenyl)...
09/19/2000
6117445Methods for the prevention and treatment of fibrosis and sclerosis
Methods of treating or preventing fibrosis and sclerosis by the administration of compositions containing A1 adenosine receptor antagonists and/or P2X purinoceptor antagonists, or combinations thereof....
09/12/2000
6110485Sterile bioerodible implant device with a retinoid for improved biocompatability
An implantable device is provided which incorporates a retinoid for improving the biocompatability of the device in tissue. The device may be bioerodible for the purpose of systemically or locally releasing a therapeutic agent in tissue or it may be a per...
08/29/2000
6074661Sterile bioerodible occular implant device with a retinoid for improved biocompatability
An implantable device is provided which incorporates a retinoid for improving the biocompatability of the device in eye tissue. The device may be bioerodible for the purpose of systemically or locally releasing a therapeutic agent in tissue or it may be a...
06/13/2000
6068851Formulation for use in the prevention of pathogen induced diseases including HIV and HSV
This invention relates to formulations comprising film-forming components capable of forming per se a physical barrier to pathogens. Thermoreversible gels such as poloxamers are particularly preferred for that use. The film-forming formulations may furthe...
05/30/2000
6063396Methods and compositions for the modulation of cell proliferation and wound healing
Implants which are capable of sustained release of a cell proliferation modulating agent, together with methods for their preparation and use, are provided. The proliferation modulating agent is associated either covalently or non-covalently with the mate...
05/16/2000
6054485Eye treatments using synthetic thyroid hormone compositions
The present invention involves the discovery that synthetic thyroid hormones can be used as compositions to reduce intraocular pressure in vivo. Methods of screening synthetic thyroid hormones for effect on intraocular pressure, aqueous pressure, hydrauli...
04/25/2000
6027745Process for producing controlled drug-release contact lens, and controlled drug-release contact lens thereby produced
A process for producing a controlled drug-release contact lens, containing a first member which forms a front fact of the lens and a second member which forms a rear face of the lens, the first and second members defining a space in the contact lens, whic...
02/22/2000
6022561Bilayers preparations
A galactolipid material from wheat, produced by extraction of crushed wheat grains and subsequent chromatography of the extracted material, and having a content of DGDG of 51.5%, was mixed with the polar solvents, water and glycerol in order to test the s...
02/08/2000
6017900Topical composition containing hyaluronic acid and nsaids
A pharmaceutical composition comprising a plurality of effective non-toxic dosage amounts of a composition for topical administration to the site of pathology or trauma of skin or exposed tissue of a human patient in need of treatment suffering from a dis...
01/25/2000
6017554Composition for treating abnormal conditions of the epithelium of bodily orifices
A stable solution cream, salve, or spray composition containing activated stabilized chlorine dioxide and phosphates, such as disodium hydrogen phosphate, sodium dihydrogen phosphate, trisodium phosphate, and sodium monofluorophosphate, is disclosed for t...
01/25/2000
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