Felix Hoffmann, a German chemist, was searching for something to relieve his father's arthritis. In doing so, he "rediscovered" acetylsalicylic acid and in 1900, patented a stable process for developing it. Hence, we have aspirin.
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| Number | Title | Issue Date |
| 3995631 | Osmotic dispenser with means for dispensing active agent responsive to osmotic gradient An osmotic active agent dispenser is comprised of a chamber having controlled permeability to an external fluid, i.e., water, and containing an osmotically effective solute which, in solution, exhibits an osmotic pressure gradient against said external fl... | 12/07/1976 |
| 3991759 | Method and therapeutic system for treating aqueous deficient dry eye Method for treating aqueous deficient dry eye by instilling a biologically compatible solute, such as sodium chloride, into the tear film continuously at a controlled rate that is sufficient to osmotically induce a continuous flow of water from the inters... | 11/16/1976 |
| 3978201 | Base for ophthalmological medicinal preparation on opthalmological medicinal film A base for ophthalmological medicinal preparations consists of a homopolymer of an amide of acrylic acid having a molecular weight from 30,000 to 1,000,000, and/or a copolymer of an amide of acrylic acid with unsaturated compounds, the molecular weight of... | 08/31/1976 |
| 3977404 | Osmotic device having microporous reservoir An osmotic device for delivering an active agent is disclosed. The device is comprised of a wall surrounding in at least a part, a reservoir containing agent. The wall is formed of a material permeable to an external fluid and impermeable to agent. The re... | 08/31/1976 |
| 3976072 | Blink-operated extracorporeal tear duct A blink-activated duct for supplying a solution to the eye of the user has a particular utility in introducing an artificial tear solution to the eye of those persons who are incapable of producing such a solution themselves. The duct consists of a reserv... | 08/24/1976 |
| 3961628 | Ocular drug dispensing system An ocular drug dispensin device for administering a drug at a controlled and continuous dosage unit rate to the eye to produce a local or systemic physiological or pharmacological effect is comprised of a shaped body insoluble in tear fluid and comprised ... | 06/08/1976 |
| 3949750 | Punctum plug and method for treating keratoconjunctivitis sicca (dry eye) and other ophthalmic aliments using same A plug of suitable dimension and material is removably inserted into the upper and/or lower punctal apertures of the eye to block the opening and the attendant canaliculus so as to thereby prevent the drainage of lacrimal fluid therethrough. The plug is c... | 04/13/1976 |
| 3946106 | Microsealed pharmaceutical delivery device The present invention is concerned with a pharmaceutical delivery device comprising a biologically acceptable silicone polymer matrix having microsealed compartments of 10-200 microns throughout, wherein the microsealed compartments contain a pharmaceutic... | 03/23/1976 |
| 3935303 | Base for ophthalmological medicinal preparations and on ophthalmological medicinal film A base for ophthalmological medicinal preparations consists of a homopolymer of an amide of acrylic acid having a molecular weight from 30,000 to 1,000,000, and/or a copolymer of an amide of acrylic acid with unsaturated compounds, the molecular weight of... | 01/27/1976 |