Did You Know...
...that Robert Adler has the dubious distinction of being the Father of the Couch Potato? Back in 1955 Adler was employed by what was then Zenith Radio Corp., where he was charged to invent something that would allow viewers to turn down the TV volume without leaving their chairs. After a series of flops (such as a wired contraption that people tripped over), Adler hit on the idea of using sound waves. Thus the Remote Control was born...
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| Number | Title | Issue Date |
| 8114432 | Treatment solution and method for preventing posterior capsular opacification by selectively inducing detachment and/or death of lens epithelial cells A treatment solution used to prevent posterior capsular opacification is applied or introduced into the lens capsular bag before, during, or after cataract surgery. The treatment solution comprises an ion transport mechanism interference agent, which either alone or... | 02/14/2012 |
| 8071119 | Controlled release implantable dispensing device and method A dispensing device having a polymer which is combined with a therapeutic agent in the form of a microparticle or nanoparticle which is “hyper-compressed” to form a controlled release dispensing device and methods of locally administering a therapeutic agent usi... | 12/06/2011 |
| 8003124 | Sustained release implants and methods for subretinal delivery of bioactive agents to treat or prevent retinal disease The invention relates to sustained release implants and to methods for treating eyes, particularly the eyes of mammals having eye disorders or diseases. By using the implants and methods described herein, the delivery of the one or more bioactive agents can be local... | 08/23/2011 |
| 7988988 | Contact lenses with mucin affinity A biomedical device, such as a contact lens, has a surface linked to a polymer comprising boronic acid moieties. The boronic acid monomeric units may be derived from an ethylenically unsaturated monomer containing a boronic acid moiety, such as a vinylphenyl boronic... | 08/02/2011 |
| 7943162 | Drug delivery device Drug delivery devices, and methods of delivering pharmaceutically active agents to a target tissue within a body using such devices, are disclosed. One drug delivery device includes a body having an internal surface for disposing on a target tissue and a well having... | 05/17/2011 |
| 7939501 | Ophthalmic and contact lens solutions containing peptides as preservative A contact lens solution comprising 0.001 to 10 weight percent or a preservative enhancer chosen from the group consisting of: D4E1, D2A21, and P-113; and at least 0.0001 weight percent of a preservative, and where the concentration of chloride in said solution is le... | 05/10/2011 |
| 7939097 | Intraocular lens containing releasable medication An intraocular implant adapted to come in contact with the aqueous humor comprises a hydrophilic polymer having a predetermined water content for implantation in an eye, an effective quantity of a medicated product for treatment of the eye being dispersed in the mas... | 05/10/2011 |
| 7883717 | Reservoir device for intraocular drug delivery A delivery device that allows for the sustained release of an agent, particularly useful for the sustained release of a therapeutic agent to limited access regions, such as the posterior chamber of the eye and inner ear. The delivery device is minimally invasive, re... | 02/08/2011 |
| 7846467 | Ocular scaffold for stem cell cultivation and methods of use The present invention relates to a device and methods for culturing stem cells, and in particular, for culturing ocular stem cells and the use of stem cells cultured using the devices and methods of the invention for the treatment of diseases. ... | 12/07/2010 |
| 7820195 | Micronized device for the delivery of biologically active molecules and methods of use thereof The invention provides micronized encapsulated cell therapy devices that are capable of delivering a biologically active molecule to the eye. Also provided are methods of using the same to deliver biologically active molecules to the eye and to treat ophthalmic diso... | 10/26/2010 |
| 7820194 | Combinations of viscoelastics for use during surgery An improved viscoelastic composition useful in the performance of ophthalmic surgical procedures and especially cataract procedures is disclosed. The embodiments of the composition comprise combinations of sodium hyaluronate and chondroitin sulfate and exhibit an im... | 10/26/2010 |
| 7780976 | Apparatus and method for delivering controlled quantities of one or more agents to the eye A flat strip of supporting material, such as filter paper, having marked reference locations on each of one or more legs, for delivering controlled quantities of one or more agents to the adnexa of the eye simultaneously upon dispensing a liquid to the strip at the ... | 08/24/2010 |
| 7758883 | Three layer artificial tear formulation An artificial tear film over the surface of an eye having a first layer in direct contact with the ocular surface, an aqueous layer over the first layer, and a layer of a phospholipid over the aqueous layer. The first layer has polyvinyl alcohol, polyvinyl acetate, ... | 07/20/2010 |
| 7749530 | Kinase inhibitors The present invention relates to drug delivery systems comprising ocular implant, which include organic molecules, capable of modulating tyrosine kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation, in combination wit... | 07/06/2010 |
| 7727544 | Treatment of myopia The present invention relates to altering the physical and/or chemical properties of at least part of at least one tissue in the eye. In a specific embodiment, it relates to the treatment and/or prevention of myopia. An activating energy source is utilized to photop... | 06/01/2010 |
| 7556822 | Biomedical compositions A method of preparing intraocular lenses in situ is disclosed. The method involves the injection of an unsaturated macromonomer of Formula I: The macromonomer is then polymerized to give a polymer suitable for use in an intra... | 07/07/2009 |
| 7553496 | VEGF-A as an inhibitor of angiogenesis and methods of using same The invention relates to methods and compositions for the treatment or prevention of ocular angiogenesis and neovascularization associated with neovascular disease. Administration of vascular endothelial growth factor (VEGF)-A into the eye when macrophage infiltrati... | 06/30/2009 |
| 7544368 | Structure for modulating intraocular pressure Embodiments of the present invention are directed to three-dimensional porous structures for modulating intraocular pressure. The structures can include a mixture of copolymers, for example, collagen and glycosaminoglycan. ... | 06/09/2009 |
| 7455855 | Delivering substance and drug delivery system using the same An object of the present invention is to prepare substances which are excellent in delivery and enable drugs to be retained in a body effectively over a long period and to construct a drug delivery system using the substances. When the delivering substance which is ... | 11/25/2008 |
| 7384648 | Implant device with a retinoid for improved biocompatibility An implant device is provided which incorporates a retinoid for improving the biocompatibility of the device in tissue. The device may be bioerodible for the purpose of systemically or locally releasing a therapeutic agent in tissue or it may be a permanent implant ... | 06/10/2008 |
| 7368127 | Biomedical devices with peptide containing coatings Biomedical devices with stable peptide coatings are provided. The coatings are formed by incorporating at least one latent reactive component into the reactive mixture, forming a medical device from said reactive mixture and reacting said medical device with a coati... | 05/06/2008 |
| 7364748 | Controlled morphologies in polymer drug for release of drugs from polymer films The present invention includes a drug release system. The drug release system comprises a bulk polymer phase and a polymeric drug-enriched phase within the bulk polymer phase. At least one drug is incorporated into the drug-enriched phase. ... | 04/29/2008 |
| 7363091 | Method of molding silicone elastomer drug carrier in an endocardial lead A drug-eluting endocardial lead and method of manufacture. The silicone elastomer of the present invention is ideally suited to a manufacturing environment due to its extended pot life and decreased curing time. A preferred silicone elastomer is comprised of a multi... | 04/22/2008 |
| 7363074 | Coatings comprising self-assembled molecular structures and a method of delivering a drug using the same A coating for an implantable medical device is disclosed, the coating including a self-assembled molecular structure. The coating can be used for altering the release rate of a therapeutic substance from the implantable device. ... | 04/22/2008 |
| 7351430 | Shape-retentive hydrogel particle aggregates and their uses The present invention is related to hydrogel particles and aggregates formed therefrom having characteristics including, without limitation, shape-retentiveness, elasticity, controllable pore sizes and controllable degradation rates that render them useful for a wid... | 04/01/2008 |
| 7351407 | Agents which regulate, inhibit, or modulate the activity and/or expression of connective tissue growth factor (CTGF) as a unique means to both lower intraocular pressure and treat glaucomatous retinopathies/optic neuropathies The present invention provides a method for lowering intraocular pressure and providing neuroprotection to a patient in need thereof by administering a therapeutically effective amount of at least one non-nucleotide or non-protein agent that inhibits expression and/... | 04/01/2008 |
| 7348022 | Biomedical composition A method of preparing intraocular lenses in situ is disclosed. The method involves the injection of an unsaturated macromonomer of the formula The macromonomer is then polymerized to give a polymer having an E modulus in th... | 03/25/2008 |
| 7338665 | Methods compositions and devices utilizing stinging cells/capsules for delivering a therapeutic or a cosmetic agent into a tissue A delivery device including at least one stinging capsule and methods of use are described. ... | 03/04/2008 |
| 7335391 | Method for coating implantable devices A method of forming a coating for an implantable medical device, such as a stent, is provided which includes applying a composition to the device in an environment having a selected pressure. ... | 02/26/2008 |
| 7335367 | Treatment of chronic chalazion and hordeolum with botulinum toxin Chalazia and hordeola are the most common lesions occurring in the human eyelid, and often recurrences are managed by surgical intervention to remove fatty inclusions within the lid with associated inflammatory reaction. The present invention provides non-surgical m... | 02/26/2008 |
| 7331944 | Ophthalmic dispenser and associated method An ophthalmic dispenser has a rigid housing defining a fluid-receiving chamber, a flexible bladder receivable within the fluid-receiving chamber, a pump coupled in fluid communication with the fluid-receiving chamber, and a nozzle having a valve defining an annular,... | 02/19/2008 |
| 7332177 | Method and formulation for treating resistance to antihypertensives and related conditions A method for the prevention or treatment of symptoms of hypertension in a patient who is resistant to antihypertensive effects of an antihypertensive compound administered in the absence of melatonin comprises administering to said patient melatonin in an amount eff... | 02/19/2008 |
| 7329402 | Methods of imaging and treatment Novel ultrasound methods comprising administering to a patient a targeted vesicle composition which comprises vesicles comprising a lipid, protein or polymer, encapsulating a gas, in combination with a targeting ligand, and scanning the patient using ultrasound. The... | 02/12/2008 |
| 7329413 | Coatings for drug delivery devices having gradient of hydration and methods for fabricating thereof Coatings for implantable medical devices, and methods for fabricating thereof, are provided. The coatings include a first polymer layer and a second polymer layer, where the second polymer has a higher degree of hydration than the first polymer. ... | 02/12/2008 |
| 7326716 | Treatment of inflammatory bowel disease The present invention provides a method of treating inflammatory bowel disease which comprises administering to an animal having ocular hypertension or glaucoma therapeutically effective amount of a piperidinyl prostaglandin E analog. ... | 02/05/2008 |
| 7326423 | Copolymerizable azo compounds and articles containing them Polymerizable light absorbing azo dyes are disclosed useful as monomers in the formation of devices such as, but not limited to ocular lenses. Specifically, intraocular lenses (IOL) are disclosed wherein one or more of the light absorbing dye is covalently bonded to... | 02/05/2008 |
| 7323209 | Apparatus and method for coating stents An apparatus and method is provided for forming coatings on stents. The apparatus includes a temperature adjusting element that can increase or decrease the temperature of the stent. The apparatus can support a stent during the application of a coating composition t... | 01/29/2008 |
| 7321000 | Ophthalmic composition containing N-acetyl-cysteine for the treatment of dry-eye syndrome An ophthalmic pharmaceutical composition containing acetylcysteine as the active ingredient having a mucolitic action, suitable for administration in eyedrops, where N-acetyl-cysteine is neutralised with base DEAE-dextrane in order to reach pH levels preferably betw... | 01/22/2008 |
| 7318932 | Coatings for drug delivery devices comprising hydrolitically stable adducts of poly(ethylene-co-vinyl alcohol) and methods for fabricating the same A polymer coating for medical devices based on a derivatized poly(ethylene-co-vinyl alcohol) is disclosed. A variety of polymers are described to make coatings for medical devices, particularly, for drug delivery stents. The polymers include poly(ethylene-co-vinyl a... | 01/15/2008 |
| 7316332 | Wearable skin treatment device Persons often encounter the need to apply some form of skin treatment when on the go. Such treatments include disinfectant, sunscreens, medications, and moisturizing lotions. The present invention comprises convenient portable skin treatment dispensers in the form o... | 01/08/2008 |
