Celebrity Inventors
Comic actor Danny Kaye received patent D166,807 for the co-design of "Blowout Toy or the Like". It's similar to one of those toys that unravels when you blow into at a birthday party except Kaye's has three blowouts going in different directions, not just one.
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| Number | Title | Issue Date |
| 8188038 | Osteogenic compositions containing a coloring agent An osteogenic composition is provided for implantation at or near a target tissue site beneath the skin, the osteogenic composition comprising a growth factor and a coloring agent, wherein the coloring agent imparts color to the growth factor to allow the user to se... | 05/29/2012 |
| 8187620 | Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents The invention relates generally to a medical device, such as an intravascular stent, for delivering a therapeutic agent to the body tissue of a patient, and a method for making such a medical device. More particularly, the invention pertains to a medical device havi... | 05/29/2012 |
| 8187621 | Methods and compositions for treating post-myocardial infarction damage Methods and compositions for treating post-myocardial infarction damage are herein disclosed. In some embodiments, a carrier with a treatment agent may be fabricated. The carrier can be formulated from a bioerodable, sustained-release substance. The resultant loaded... | 05/29/2012 |
| 8187622 | Use of nonionic esters in a coating for surfaces coming in contact with blood The present invention relates to methods for coating at least one surface of a medical device for improving the hemocompatibility of said surface. Further, the invention relates to medical devices comprising surfaces, coated with a coating composition containing a n... | 05/29/2012 |
| 8187623 | Medical copolymers Medical copolymers are provided which comprise (a) a polymer backbone comprising (i) a plurality of —C═C— groups within the polymer backbone, (ii) a plurality of —R9— groups within the polymer backbone, wherein R9 comprises a radical-... | 05/29/2012 |
| 8182830 | Hydrogen sulfide generating polymers Described herein are hydrogen sulfide (H2S) generating polymers and polymer systems suitable for coating or forming medical devices and methods for making and using the same. More specifically, described are H2S generating polymers comprising a... | 05/22/2012 |
| 8182829 | Drug eluting implantable medical device with hemocompatible and/or prohealing topcoat The present invention relates to implantable medical devices coated with polymer having hemocompatible and/or prohealing moieties appended thereto and to their use in the treatment of vascular diseases. ... | 05/22/2012 |
| 8178123 | Method for augmentation of intraepithelial and systemic exposure of therapeutic agents having substrate activity for cytochrome P450 enzymes and membrane efflux systems following vaginal and oral cavity administration A vaginal or buccal delivery of therapeutic agents having a substrate affinity for metabolic cytochrome P-450 enzymes and membrane efflux transporter systems. A method for augmentation of systemic exposure to the therapeutic agents having a substrate affinity for cy... | 05/15/2012 |
| 8173149 | Method for producing porous β-tricalcium phosphate granules A porous β-tricalcium phosphate material for bone implantation is provided. The multiple pores in the porous TCP body are separate discrete voids and are not interconnected. The pore size diameter is in the range of 20-500 μm, preferably 50-125 μm. The porous β-... | 05/08/2012 |
| 8173150 | Stable non-aqueous single phase viscous vehicles and formulations utlizing such vehicles This invention relates to stable non-aqueous single phase viscous vehicles and to formulations utilizing such vehicles. The formulations comprise at least one beneficial agent uniformly suspended in the vehicle. The formulation is capable of being stored at temperat... | 05/08/2012 |
| 8173151 | Antimicrobial material and method for making the same This invention provides a modified catheter biomaterial that provides both immediate, and long-term microbiocidal effects on otherwise antibiotic-resistant strains of microorganisms. The material, which exhibits good mechanical performance characteristics for medica... | 05/08/2012 |
| 8168213 | Medical devices having coating with improved adhesion According to an aspect of the present invention, a medical device is provided which comprises a metallic substrate and polymeric region disposed over and in contact with the metallic substrate. The polymeric region comprises (a) a block copolymer that comprises (i) ... | 05/01/2012 |
| 8163302 | Methods of making and using surfactant polymers Comblike, surfactant polymers for changing the surface properties of biomaterials are provided. Such surfactant polymers comprise a polymeric backbone of repeating monomeric units having functional groups for coupling with side chains, a plurality of hydrophobic sid... | 04/24/2012 |
| 8158141 | Cell transplant device for treatment of corneal wound A device for transplanting a graft such as a layer or layers of cultivated, autologous, allogenic or xenogenic cells to cover an accidental or surgical wound. The graft is cultivated and carried on a bed of collagen or other dissolvable or releasable material mounte... | 04/17/2012 |
| 8158142 | 3-deazaadenosine prevents atherosclerosis and graft vasculopathy A stent is coated with 3-deazaadenosine or an analog of 3-deazaadenosine for the prevention and/or treatment of vascular disease or graft rejection. ... | 04/17/2012 |
| 8147862 | Highly mineralized osteogenic sponge compositions and uses thereof Osteogenic sponge compositions having enhanced osteoinductive properties for use in bone repair are described. The compositions include a quickly resorbable porous carrier, a more slowly resorbed mineral scaffold and an osteogenic factor, preferably a bone morphogen... | 04/03/2012 |
| 8147863 | Polyarylates for drug delivery and tissue engineering Biocompatible polyarylates of diphenol compounds and poly(alkylene oxide) dicarboxylic acids, articles formed therefrom and therapeutic uses are disclosed. ... | 04/03/2012 |
| 8147859 | Implantable material having patterned surface of raised elements and photochemically altered elements and method of making same Implantable materials having defined patterns of affinity regions for binding endothelial cells and providing for directed endothelial cell migration across the surface of the material. The affinity regions include photochemically altered regions of a material surfa... | 04/03/2012 |
| 8147860 | Porous calcium phosphate bone material Porous calcium phosphate implant compositions that approximate the chemical composition of natural bone mineral are provided. In addition to calcium phosphate, the compositions include an effervescent agent to promote the formation of interconnected pores and a cohe... | 04/03/2012 |
| 8147861 | Antimicrobial implant A method of building an orthopedic implant including the steps of mixing a powder having antimicrobial properties with a biocompatible powder to form a mixture. Next, the mixture is deposited on top of a substrate. The substrate may be part of the finished product o... | 04/03/2012 |
| 8142807 | Bone void fillers and methods of making the same The invention relates to a material for use as bone void filler comprising soluble keratin protein. The material may be in the form of a putty, gel or emulsion. Additional components may be added to the material to improve handling characteristics and bone enhanceme... | 03/27/2012 |
| 8142808 | Method of treating joints with hydrogel implants Implantable biomaterials, particularly hydrogel substrates with porous surfaces, and methods for enhancing the compatibility of biomaterials with living tissue, and for causing physical attachment between biomaterials and living tissues are provided. Also provided a... | 03/27/2012 |
| 8137688 | Hydroxyphenyl cross-linked macromolecular network and applications thereof A synthetic nucleus pulposus is provided that is useful in treatment of degenerative disc disease, augmentation of a degenerate disc, and alleviation of back pain. In an embodiment the synthetic nucleus pulposus comprises hyaluronan macromolecules that have been cro... | 03/20/2012 |
| 8137687 | 4-aza-caprolactone-based polymeric compositions useful for the manufacture of biodegradable medical devices and as medical device coatings N-substituted 4-aza-caprolactone biodegradable polymers, including derivatives thereof, useful for making implantable medical devices and coatings therefore are provided. The medical devices and coatings of the present invention can also be used for in situ controll... | 03/20/2012 |
| 8137686 | Nonwoven tissue scaffold A biocompatible meniscal repair device is disclosed. The tissue repair device includes a scaffold adapted to be placed in contact with a defect in a meniscus, the scaffold comprising a high-density, dry laid nonwoven polymeric material and a biocompatible foam. The ... | 03/20/2012 |
| 8128952 | Ligand-mediated controlled drug delivery Disclosed are systems and methods that can be utilized to define and control the delivery rate of a biological agent from a carrier matrix such as a biocompatible hydrogel. The carrier matrices of the present invention can include ligands incorporated within the mat... | 03/06/2012 |
| 8128953 | Conductive therapeutic coating for medical device An implantable medical device includes a housing and a coating disposed on the housing. The coating includes a conductive carrier and a therapeutic agent, e.g. an anti-infective agent such as silver particles. The conductive carrier can be any suitable conductive ma... | 03/06/2012 |
| 8124118 | Composition comprising biodegradable hydrating ceramics for controlled drug delivery The present invention relates to a drug carrier composition comprising i) one or more biodegradable hydrating ceramics ii) one or more expandable agents, and iii) sorbed aqueous medium which in solid form has a ruptured structure. The function of the expandable agen... | 02/28/2012 |
| 8119151 | Spread coating a medical device The present invention is directed to methods, systems, devices, and kits for coating portions of a medical device or other work piece as well as to medical devices that have themselves been coated in accord with the invention. Under methods of the invention, portion... | 02/21/2012 |
| 8114431 | Biomolecular coating for implants Methods and compositions are provided for improving tissue growth and device integration in vivo. Substrates and devices coated with an α2β1 or α5β1 integrin-specific ligand are provided. The substrates and devices coa... | 02/14/2012 |
| 8110209 | Intracutaneous injection The delivery of biopharmaceutical and other therapeutic agents parenterally to an animal via a minimally invasive, low pain administration is provided. The agents are delivered to the patient via, e.g., the epidermal, dermal, or subcutaneous layer of the skin in a c... | 02/07/2012 |
| 8110211 | Medicated coatings for implantable medical devices including polyacrylates A polymer for a medical device, particularly for a drug eluting stent, is described. The polymer can be derived from n-butyl methacrylate and can have a degree of an elongation at failure from about 20% to about 500%. ... | 02/07/2012 |
| 8110210 | Nonwoven tissue scaffold A biocompatible meniscal repair device is disclosed. The tissue repair device includes a scaffold adapted to be placed in contact with a defect in a meniscus, the scaffold comprising a high-density, dry laid nonwoven polymeric material and a biocompatible foam. The ... | 02/07/2012 |
| 8110212 | Bioactive thermogelling polymer systems and methods of their use Hydrogels comprising poly(N-alkylacrylamide), poly(alkyleneglyco)di-acrylate or methacrylate, cross-linking agent, a source of calcium ions, and water are described, as well as methods of their preparation and use. ... | 02/07/2012 |
| 8106014 | Methods and apparatus for enhanced growth of peripheral nerves and nervous tissue A medical device comprises a tubular body having a lumen and a long axis; and a plurality of silk elements laid substantially parallel along the long axis of the lumen of the tubular body. A method of manufacturing the medical device comprises forming the tubular bo... | 01/31/2012 |
| 8101199 | Des-methyl-tocopherol therapy for restenosis prevention A stent is provided in combination with delivery of a tocopherol agent, and in particular a des-methyl tocopherol agent, and further beneficially a gamma-tocopherol agent, so as to reduce restenosis along the vessel or other lumenal wall where the stent is implanted... | 01/24/2012 |
| 8092823 | Osteogenic implants with combined implant materials and methods for same Described are osteogenic implants that include a first implant material covered at least in part by a second implant material carrying an osteogenic protein such as a bone morphogenic protein. The first implant material can comprise a mineral and provide an inner sc... | 01/10/2012 |
| 8092822 | Coatings including dexamethasone derivatives and analogs and olimus drugs The present invention encompasses a coating on the surface of a substrate and the coated substrates. The coating includes a polymer, an olimus drug (sirolimus, everolimus, zotarolimus, etc.), and a dexamethasone derivative. The polymer may be a hydrophobic polymer, ... | 01/10/2012 |
| 8092821 | Medical devices having polymeric regions with improved adhesion According to an aspect of the present invention, implantable or insertable medical devices are provided, which contain at least one polymeric region in contact with a metallic region. The polymeric region contains at least one block copolymer that contains at least ... | 01/10/2012 |
| 8088402 | Bone growth compositions and methods The present invention provides an improved technique for spinal fusion involving the administration of an HMG-CoA reductase inhibitor to a fusion. The HMG-CoA reductase inhibitor is preferably delivered to the site by a carrier. More preferably, the HMG-CoA reductas... | 01/03/2012 |
