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Class 424/422 - Implant or insert


Subclass of Class 424 - Drug, bio-affecting and body treating compositions
Definition: Subject matter in which the composition is in a special
No. of patents: 2056
Last issue date: 05/29/2012


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NumberTitleIssue Date
7332160Medical device and method for tissue removal and repair
The present invention relates to medical devices that are to be implanted or inserted into the body of a patient for the purpose of removing undesired body tissues. In one embodiment of the invention the medical device comprises a body tissue removal agent for remov...
02/19/2008
7332183Multilayer dosage forms containing NSAIDs and triptans
The present invention is directed to multilayer pharmaceutical tablets in which an NSAID and a triptan are present in separate and distinct layers. The layers are in a side-by-side configuration, which allows the dissolution of triptan and NSAID to occur independent...
02/19/2008
7332525Method of treatment of prostate cancer and composition for treatment thereof
A method and composition for the treatment of prostate cancer comprises an effective amount of a nonsteroidal antiandrogen and an effective amount of a selective estrogen receptor modulator. The composition has fewer side effects such as breast tenderness and gyneco...
02/19/2008
7329413Coatings for drug delivery devices having gradient of hydration and methods for fabricating thereof
Coatings for implantable medical devices, and methods for fabricating thereof, are provided. The coatings include a first polymer layer and a second polymer layer, where the second polymer has a higher degree of hydration than the first polymer. ...
02/12/2008
7328707Implant system and method for bulking tissue
A system for placing an implant in the body includes an elongated member having at least one inner lumen extending from a proximal end portion of the member to an opening in a distal end portion of the member. At least one compressible implant is in the inner lumen ...
02/12/2008
7329402Methods of imaging and treatment
Novel ultrasound methods comprising administering to a patient a targeted vesicle composition which comprises vesicles comprising a lipid, protein or polymer, encapsulating a gas, in combination with a targeting ligand, and scanning the patient using ultrasound. The...
02/12/2008
7326422Dissolvable oxides for biological applications
Controllably dissolvable silica-xerogels prepared via sol-gel process and their use. A delivery device including controllably dissolvable silica-xerogel into which structure a biologically active agent is incorporated. Pharmaceutical preparations including this devi...
02/05/2008
7326571Decellularized bone marrow extracellular matrix
The invention is directed to compositions comprising decellularized bone marrow extracellular matrix and uses thereof. Methods for repairing or regenerating defective, diseased, damaged or ischemic tissues or organs in a subject, preferably a human, using the decell...
02/05/2008
7322965Infection-resistant medical devices
A method for preventing medical device-associated microorganism infection includes the steps of providing a medical device and incorporating an effective amount of an oxazolidinone compound, such as linezolid, into the medical device. ...
01/29/2008
7323160Method of treating a patient's teeth using fluoride releasing glass composition
A method of treating sensitive teeth includes (1) attaching a fluoride releasing glass composition to a person's tooth, and (2) allowing fluoride to be slowly released over time in order to reduce chronic and/or acute tooth sensitivity. A preferred glass composition...
01/29/2008
7323189Liquid and low melting coatings for stents
A method for forming liquid coatings for medical devices such as stents and angioplasty balloons is provided. The liquid coatings can be made from biodegradable materials in liquid, low melting solid, or wax forms, which preferably degrade in the body without produc...
01/29/2008
7323445Methods and compositions for healing and repair of articular cartilage
Methods and compositions are provided for the treatment of articular cartilage defects and disease involving the combination of tissue, such as osteochondral grafts, with active growth factor. The active growth factor is preferably a composition containing at least ...
01/29/2008
7320798Coatings, coated articles and methods of manufacture thereof
A multi-layer coating is particularly useful for the coating of implants such as orthopedic and dental implants, particularly metallic implants. The first layer comprises a dense material insoluble and inert in body fluids. The second layer comprises apatite and a b...
01/22/2008
7320799Coatings, coated articles and methods of manufacture thereof
A multi-layer coating is particularly useful for the coating of implants such as orthopedic and dental implants, particularly metallic implants. The multi-layer coating has both high bond strength to implants and excellent bioactivity with the surrounding body tissu...
01/22/2008
7318931Sustained release formulation
A composition comprises a protein, a polyol, and a metal. The protein is stabilized by the polyol and the metal, and is protected from denaturing when in contact with an organic solvent. The polyol may be a hydrocarbon containing two or more hydroxyl groups (—OH) ...
01/15/2008
7319032Non-sugar sweeteners for use in test devices
The present invention provides methods, compositions, and kits for rapid detection of analytes in a sample. Surprisingly, it has been found that bulking materials having non-sugar sweeteners effectively enhance chromatographic detection methods by providing componen...
01/15/2008
7319035Biological scaffolding material
The invention provides methods of generating a natural, living biological matrix that can serve as, or form a part of, a natural biological scaffold. The matrix is generated by incubating together biological cells and cellular debris. Any naturally occurring cell ca...
01/15/2008
7318932Coatings for drug delivery devices comprising hydrolitically stable adducts of poly(ethylene-co-vinyl alcohol) and methods for fabricating the same
A polymer coating for medical devices based on a derivatized poly(ethylene-co-vinyl alcohol) is disclosed. A variety of polymers are described to make coatings for medical devices, particularly, for drug delivery stents. The polymers include poly(ethylene-co-vinyl a...
01/15/2008
7316811Multi-arm polypeptide-poly (ethylene glycol) block copolymers as drug delivery vehicles
The invention provides a multi-arm block copolymer for use in delivering a variety of bioactive agents. The copolymer of the invention contains a central core from which extend multiple (3 or more) copolymer arms. Each copolymer arm possesses an inner polypeptide se...
01/08/2008
7311970Medical device having surface modification with superoxide dismutase mimic
A medical device comprising a substrate having a plasma polymerized functionality bonded to at least a portion of the substrate. A superoxide dismutase mimic agent having a complimentary functional group to the plasma polymerized functionality is bonded to the porti...
12/25/2007
7311980Polyactive/polylactic acid coatings for an implantable device
A polymeric coating for a medical device that comprises poly(lactic acid) and a block copolymer including blocks of poly(ethylene glycol) and poly(butylene terephthalate) is provided. ...
12/25/2007
7309497Injectable pharmaceutical composition for systematic administration of pharmacologically active ingredients
The invention relates to novel pharmaceutical compositions for the systemic administration of pharmacologically active ingredients. The invention relates in particular to an injectable pharmaceutical composition comprising (a) a pharmacologically active ingredient i...
12/18/2007
7304035Stimulation of bone growth with thrombin peptide derivatives
Disclosed is a method of stimulating bone growth at a site in a subject in need of osteoinduction. The method comprises the step of administering a therapeutically effective amount of an agonist of the non-proteolytically activated thrombin receptor to the site....
12/04/2007
7303575Embolism protection devices
Embolism protection devices can be formed with a biocompatible expandable polymer that can expand upon release within a patient's vessel. Upon release, the structure can be configured to filter flow through the vessel. The material of the embolism protection devices...
12/04/2007
7303756Multiphase system
The invention relates to a preparation comprising a carrier phase and at least one further phase which cannot be mixed with the carrier phase or only partially mixed therewith, wherein the change in ambient conditions alters the viscosity of the carrier phase. The i...
12/04/2007
7303757Biocompatible phase invertable proteinaceous compositions and methods for making and using the same
Biocompatible phase invertable proteinaceous compositions and methods for making and using the same are provided. The subject phase invertable compositions are prepared by combining a proteinaceous substrate and a cross-linker. The proteinaceous substrate includes o...
12/04/2007
7303912Cultures of GFAP nestin cells that differentiate to neurons
Cultures of cells immunoreactive for glial fibrillary acidic protein (GFAP), as well as for the intermediate filament marker nestin were grown in a medium including epidermal growth factor (EGF) and serum. The cultured cells had the morphology of astroglial cells. T...
12/04/2007
7304277Resonator with adjustable capacitor for medical device
An apparatus, system and method of a resonator device with an adjustable capacitor for allowing the resonance frequency (F) of the resonator device to continue to be matched to the Larmor frequency of the MRI system. The resonator device includes an inductor coil, a...
12/04/2007
7300662Drug/drug delivery systems for the prevention and treatment of vascular disease
A drug and drug delivery system may be utilized in the treatment of vascular disease. A local delivery system is coated with rapamycin or other suitable drug, agent or compound and delivered intraluminally for the treatment and prevention of neointimal hyperplasia f...
11/27/2007
7300772BMP products
Purified BMP-2 and BMP-4 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair. ...
11/27/2007
7300661Adding microscopic porosity to the surface of a microcoil to be used for medical implantation
A vasoocclusive microcoil for therapeutic treatment of a patient's vasculature includes a surface with a plurality of voids or pores therein, and a therapeutic or bioactive material disposed within the plurality of voids or pores. The therapeutic or bioactive materi...
11/27/2007
7300465Intervertebral allograft spacer
An allogenic intervertebral implant for fusing vertebrae is disclosed. The implant is a piece of allogenic bone conforming in size and shape with a portion of an end plate of a vertebra. The implant has a wedge-shaped profile to restore disc height and the natural c...
11/27/2007
7297758Method for extending shelf-life of constructs of semi-crystallizable polymers
This invention relates to a method of extending the shelf-life of constructs, in particular bioabsorbable stents, comprising semi-crystalline polymers by increasing the crystallinity of the polymers. ...
11/20/2007
7294329Poly(vinyl acetal) coatings for implantable medical devices
A coating for a medical device, particularly for a drug eluting stent, is described. The coating includes a polyacetal-based polymer. ...
11/13/2007
7294278Method for oxygenating wastewater
A method and apparatus creates gas-enriched fluid that is used to treat wastewater. In one embodiment, the wastewater is withdrawn from a supply of wastewater to be treated, and the wastewater is delivered in an atomized manner to a vessel pressurized with gas to fo...
11/13/2007
7294345Otorhinological delivery device
The invention relates to an otorhinological delivery device comprising at least one pharmaceutically active agent. According to the invention the device comprises a core comprising said at least one pharmaceutically active agent wherein said core is made of an elast...
11/13/2007
7294350Healing powder and method of use thereof
A wound healing powder, comprising a sugar selected from the group consisting of one or more pharmaceutically acceptable monosaccharides and disaccharides, in an amount of at least 25% by weight of the powder mixture; and an absorbent agent which forms a bioabsorbab...
11/13/2007
7291345Formable and settable polymer bone composite and method of production thereof
A composite osteoimplant. The osteoimplant includes a polymer and bone-derived particles. The composite is adapted and constructed to be formable during or immediately prior to implantation and to be set after final surgical placement. ...
11/06/2007
7291673Conjugate addition reactions for the controlled delivery of pharmaceutically active compounds
The invention features polymeric biomaterials formed by nucleophilic addition reactions to conjugated unsaturated groups. These biomaterials may be used for medical treatments. ...
11/06/2007
7291497Medical device for analyte monitoring and drug delivery
The invention relates to an ingestible, implantable or wearable medical device comprising a microarray which comprises a bioactive agent capable of interacting with a disease marker biological analyte; a reservoir which comprises at least one therapeutic agent and i...
11/06/2007
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