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Patent No. 6637829

Decorative Jeweled Wheel Cover

An improved wheel is provided wherein decorative items such as gem stones are embedded in either the wheel surface, a special mounting section attached to the wheel surface, or to a spoke strap that wraps around each spoke and positions embedded gem stones on the outside surface of the spoke.

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Class 424/422 - Implant or insert


Subclass of Class 424 - Drug, bio-affecting and body treating compositions
Definition: Subject matter in which the composition is in a special
No. of patents: 2056
Last issue date: 05/29/2012


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NumberTitleIssue Date
7101566Polymer coated microparticles for sustained release
The present invention is directed to sustained release microparticle formulation for parenteral administration of biologically active substances, especially drugs. More specifically it relates to coated drug containing microparticles, wherein the coating is a synthe...
09/05/2006
7101862Hemostatic compositions and methods for controlling bleeding
The invention provides hemostatic compositions useful to promote hemostasis at active bleeding wound sites. The hemostatic compositions typically include an article containing cellulose, e.g., cotton gauze, and a polysaccharide covalently linked to the cellulose, or...
09/05/2006
7100613Braided implant for snoring treatment
A method and apparatus for treating snoring of a patient includes providing an implant for altering a dynamic response of a soft palate of the patient to airflow past the soft palate. The implant is embedded in the soft palate to alter the dynamic response. The impl...
09/05/2006
7097771In-tank time release ion exchange resin containing a fuel additive
The invention provides a device containing an ion-exchange resin to which is chemically bound a fuel additive material which will gradually be released from the resin into a fuel in which the device is placed. ...
08/29/2006
7097849Injectable aqueous dispersions of propofol
Irritation upon injection of a formulation containing propofol is reduced or substantially eliminated by administering a stable, sterile, and antimicrobial aqueous dispersion comprising a water-insoluble microdroplet matrix of mean diameter from about 50 nm to about...
08/29/2006
7097855Transdermal thermal polymerization
An invention for polymerizing or crosslinking a prepolymer using a water soluble, thermal polymerization initiator is disclosed. The prepolymer mixed with the initiator is injected or placed into an animal's body, and heat is applied over the site of the injection t...
08/29/2006
7094550Method to determine TGF-beta
A method for treating or preventing cardiovascular pathologies by administering a compound of the formula (I): wherein Z is C═O or a covalent bond; Y is H or O(C1–C4)alkyl, R1
08/22/2006
7094256Coatings for implantable medical device containing polycationic peptides
Coatings for implantable medical devices and methods for fabricating the same are disclosed. The coatings include carboxylated acrylates and polycationic peptides, for example R7. ...
08/22/2006
7091015Fibrinogen-based tissue adhesive
The present invention provides a fibrinogen-based tissue adhesive which contains an elastase inhibitor. ...
08/15/2006
7091175Angiogenesis drugs
A novel angiogenesis drug which can be clinically used for therapies of human or the like is disclosed. The angiogenesis drug according to the present invention comprises a peptide as an effective component, which has a prescribed amino acid sequence and has an angi...
08/15/2006
7090861Sustained release delivery systems for solutes
The present invention relates to devices that allow for linear, sustained-release of solutes with adjustable initial-release kinetics. In particular, the present invention relates to devices for delivering substances to the body of an animal. The present invention a...
08/15/2006
7087237Ocular solutions
Containing at least one macrolide antibiotic and/or mycophenolic acid provide anti-inflammatory, anti-cell proliferation, anti-cell migration, anti-angiogenesis, antimicrobial, and antifungal effects. In one embodiment, the solution is administered intraocularly aft...
08/08/2006
7087087Implants formed of coupled bone
The present invention relates to an implant comprising two or more bone fragments that are combined to form a single unit. Cancellous bone or cortical bone is removed from a source and fashioned into bone components with desirable shapes and sizes. The bone componen...
08/08/2006
7087241Compositions and methods for minimizing adverse drug experiences associated with oxybutynin therapy
The present invention provides compositions and methods for administering oxybutynin while minimizing the incidence and or severity of adverse drug experiences associated with oxybutynin therapy. In one aspect, these compositions and methods provide a lower plasma c...
08/08/2006
7087082Bone implants with central chambers
A bone fusion implant for repair or replacement of bone includes a hollow body formed from at least two bone fragments which are configured and dimensioned for mutual engagement and which are coupled together. The hollow body may be formed of autograft, allograft, o...
08/08/2006
7087247Polyesters, method for producing same, and depot medicaments produced from these polyesters
The invention relates to novel absorbable polyesters, produced by ring-opening polymerisation of hydroxycarboxylic acids in the presence of a polyol containing an electrolyte, in an extruder. In particular, the invention relates to novel polylactide glycolide polyes...
08/08/2006
7087263Rare limiting barriers for implantable medical devices
A coating for a medical device, particularly for a drug eluting stent, is described. The coating comprises a polymer having a weight-average molecular weight between about 200,000 and about 250,000 Daltons or a polydispersity index between about 2.6 and about 3.0.
08/08/2006
7087577Method of promoting natural bypass
An angiogenic factor comprising a mixture of proteins derived from bone. The angiogenic protein mixture is produced by a series of steps that allow the proteins to be kept in solution. The angiogenic mixture of bone proteins is produced by a multi-step process that ...
08/08/2006
7087709Polymers for delivering nitric oxide in vivo
Disclosed are novel polymers derivatized with at least one —NOx group per 1200 atomic mass unit of the polymer. X is one or two. In one embodiment, the polymer is an S-nitrosylated polymer and is prepared by reacting a polythiolated polymer with a nitro...
08/08/2006
7084121Mixtures of calcitonin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
A mixture of conjugates in which each conjugate in the mixture comprises a calcitonin drug coupled to an oligomer that includes a polyalkylene glycol moiety is disclosed. The mixture may lower serum calcium levels in a subject by 10, 15 or even 20 percent or more. M...
08/01/2006
7084188Surface modification of contact lenses
Provided are surface modified contact lenses formed from one or more fumaric- or itaconic-containing prepolymers having reactive functionality that is complimentary to reactive hydrophilic polymers. ...
08/01/2006
7083802Treatment of ocular disease
A formulation to treat ocular conditions such as dry eye disease, as well as other conditions, is disclosed. Rapamycin and/or ascomycin is administered intraocularly, such as by topical application, injection into the eye, or implantation in or on the eye. For examp...
08/01/2006
7083803Ocular solutions
Ocular solutions containing at least one macrolide antibiotic and/or mycophenolic acid provide anti-inflammatory, anti-cell proliferation, anti-cell migration, anti-angiogenesis, antimicrobial and antifungal effects. In one embodiment, the solution is administered i...
08/01/2006
7084114Mixtures of insulin drug-oligomer comprising polyalkylene glycol
A mixture of conjugates in which each conjugate in the mixture comprises an insulin drug coupled to an oligomer that includes a polyalkylene glycol moiety is disclosed. The mixture may exhibit higher in vivo activity than a polydispersed mixture of similar conjugate...
08/01/2006
7083777Immunomodulating polymers
A pharmaceutical composition consisting of identical repeating units, each unit having a charge motif composed of a positively charged free amino moiety and a negatively charged moiety, wherein the positively charged free amino moiety and the negatively charged moie...
08/01/2006
7083644Implantable prostheses with improved mechanical and chemical properties
Prostheses with improved chemical and mechanical properties manufactured that includes a radiation resistant and hydrolytically stable biocompatible fabric having outer and first and second ends with a textile fabric that includes a naphthalene dicarboxylate derivat...
08/01/2006
7083572Therapeutic delivery systems
Targeted therapeutic delivery systems comprising gas- or gaseous precursor-filled lipid microspheres comprising a therapeutic are described. Methods for employing such microspheres in therapeutic delivery applications are also provided. Targeted therapeutic d...
08/01/2006
7082336Implantable intravascular device for defibrillation and/or pacing
The present application describes an intravascular implantable pacing and/or defibrillation system. The described system includes a pulse generator that is implantable within a blood vessel and proportioned to blood flow through the blood vessel, and at least one le...
07/25/2006
7081161Biocompatible cement containing reactive calcium phosphate nanoparticles and methods for making and using cement
A cement powder is disclosed that contains reactive tricalcium phosphate nanoparticles and other ingredients required to form a cementous material. Methods of making the reactive tricalcium phosphate nanoparticles, the cement powder, the cement paste, and cured ceme...
07/25/2006
7077821Implant system and method for bulking tissue
A system for placing an implant in the body includes an elongated member having at least one inner lumen extending from a proximal end portion of the member to an opening in a distal end portion of the member. At least one compressible implant is in the inner lumen ...
07/18/2006
RE39196Nanocrystalline apatites and composites, prostheses incorporating them, and method for their production
Methods for synthesis of nanocyrstalline apatites are presented, as well as a series of specific reaction parameters that can be adjusted to tailor, in specific ways, properties in the recovered product. Particulate apatite compositions having aveage crystal size of...
07/18/2006
7078221Nucleic acid molecules encoding osteogenic proteins
Disclosed are 1) osteogenic devices comprising a matrix containing osteogenic protein and methods of inducing endochondral bone growth in mammals using the devices; 2) amino acid sequence data, amino acid composition, solubility properties, structural features, homo...
07/18/2006
7078015Ultrasound imaging and treatment
Methods of and apparatus for preparing temperature activated gaseous precursor-filled liposomes are described. Gaseous precursor-filled liposomes prepared by these methods are particularly usefull for example, in ultrasonic imaging applications and in therapeutic dr...
07/18/2006
7074803Opioid formulations
The present invention provides high-concentration formulations of opioids such as fentanyl or fentanyl congeners. The formulation of the invention comprises fentanyl or a fentanyl congener in concentrations significantly in excess of conventional formulations, e.g.,...
07/11/2006
7074425Hemostatic compositions and methods
The present invention provides methods and compositions involving resorbable hemostatic agents that have the essential absence of microfibrillar collagen. Resorbable hemostatic agents of the present invention comprise polyethylene glycol, which controls bleeding in ...
07/11/2006
7074432Method of modifying the release profile of sustained release compositions
The present invention relates to a method for the sustained release in vivo of a biologically active agent comprising administering to a subject in need of treatment an effective amount of a sustained release composition comprising a biocompatible polymer having the...
07/11/2006
7074221Anterior cervical plate system
Anatomically contoured anterior cervical plates with bone ingrowth surfaces, providing for intersegmental compressive preloading, and a rigid and locked interface to all of the bone screws, with those engaging the vertebrae deployed in highly convergent pairs. The b...
07/11/2006
7070798Coatings for implantable medical devices incorporating chemically-bound polymers and oligomers of L-arginine
A coating for an implantable medical device is disclosed. The coating comprises a polymer and an amino acid chemically bonded, attached or conjugated to the polymer. In one embodiment, the coating can include a therapeutic substance. In lieu of bonding the amino aci...
07/04/2006
7070809Hydrogel biomedical articles
Hydrogel biomedical articles formed from macromers having a polymeric backbone comprising 1,2-diol and/or 1,3-diol units, such as polyvinyl alcohol, and pendant chains bearing crosslinkable groups and, optionally, other modifiers. ...
07/04/2006
7070557Tissue graft material and method of making
The present invention relates to a method of making a tissue graft material. The method includes placing body tissue and a blood component in a chamber and extruding the body tissue and blood component from an opening in the chamber to form the tissue graft material...
07/04/2006
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