Comic actor Danny Kaye received patent D166,807 for the co-design of "Blowout Toy or the Like". It's similar to one of those toys that unravels when you blow into at a birthday party except Kaye's has three blowouts going in different directions, not just one.
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| Number | Title | Issue Date |
| 8158133 | Pharmaceutical composition useful for vaccines A pharmaceutical composition including at least a mixture of at least one oil, at least one surfactant and an aqueous phase, itself including at least one active substance, the pharmaceutical composition not being in the form of an emulsion, but in the form of an oi... | 04/17/2012 |
| 8063020 | Resuscitation fluid A method for treating conditions related to lack of blood supply with a lipid based resuscitation fluid is disclosed. The resuscitation fluid contains a lipid component and an aqueous carrier. The lipid component forms an emulsion with the aqueous carrier. The resus... | 11/22/2011 |
| 7943154 | Method for producing multiple emulsions that are stable in storage A process is described for the preparation of storage-stable, multiple emulsions of the water/oil/water (W/O/W) type which comprise one or more active ingredients. The process comprises the steps a) stirring the active ingre... | 05/17/2011 |
| 7838019 | Composition comprising iscom particles and live micro-organisms Iscom particles can be used as an adjuvant for preparing of an antigenic composition which comprises live micro-organisms and/or killed micro-organisms and/or antigenic molecules. A composition may comprise at least one iscom particle and one or more live micro-orga... | 11/23/2010 |
| 7641911 | Immunological adjuvant compositions The present invention is directed to novel adjuvant compositions, which target the cellular and/or humoral arms of immunity. According to an embodiment of the invention, an oil-in-water adjuvant composition is provided that comprises: (a) water; (b) a metabolizable ... | 01/05/2010 |
| 7608279 | Vaccine formulations The present invention provides for a novel oil-in-water (O/W) emulsion, with increased stability in the presence of bacterial or viral suspensions, especially those concentrated and non-purified or weakly purified. The emulsion of the present invention can act as ve... | 10/27/2009 |
| 7425336 | Canine influenza vaccines The present invention encompasses influenza vaccines, in particular canine influenza vaccines. The vaccine may be a recombinant poxvirus vaccine or an inactivated vaccine. The invention also encompasses recombinant poxvirus vectors encoding and expressing influenza ... | 09/16/2008 |
| 7381422 | Method for producing sterile polynucleotide based medicaments The present invention relates to a novel method for producing formulations comprising a polynucleotide, block copolymer and cationic surfactant. The formulations produced by the current method are suitable for use in polynucleotide based medicaments. A suitable meth... | 06/03/2008 |
| 7374751 | QS-21 and IL-12 as an adjuvant combination Adjuvant compositions comprising an effective amount IL-12 and QS-21 are disclosed. Immunogenic, vaccine and pharmaceutical compositions comprising a mixture of antigen and an adjuvant composition comprising an effective amount of IL-12 and QS-21 are also disclosed.... | 05/20/2008 |
| 7371395 | Vaccine formulations The present invention provides for a novel oil-in-water (O/W) emulsion, with increased stability in the presence of bacterial or viral suspensions, especially those concentrated and non-purified or weakly purified. The emulsion of the present invention can act as ve... | 05/13/2008 |
| 7365107 | Marking liquid The invention relates to a marking liquid which contains a polymer dispersion with particles which are colored with marking agent, optionally further dyes and marking agents, one or more salts of a polyvalent, in particular bi- or trivalent cation, water and optiona... | 04/29/2008 |
| 7361352 | Influenza immunogen and vaccine A chimeric, carboxy-terminal truncated hepatitis B virus nucleocapsid (HBc) protein is disclosed that contains an immunogen for inducing the production of antibodies to the influenza M2 protein. An immunogenic influenza sequence in two to four copies is preferably e... | 04/22/2008 |
| 7357936 | Adjuvant systems and vaccines The present invention provides vaccine and adjuvant formulation comprising an immunostimulant and a metal salt. The immunostimulant is adsorbed onto a particle of metal salt and the resulting particle is essentially devoid of antigen. ... | 04/15/2008 |
| 7351413 | Stabilized HBc chimer particles as immunogens for chronic hepatitis A method of treating chronic hepatitis B is disclosed that comprises administering a T cell-stimulating amount of a vaccine to a patient. The vaccine comprises an immunogenic amount of chimeric, carboxy-terminal truncated hepatitis B virus nucleocapsid (core) protei... | 04/01/2008 |
| 7347163 | Microbial feedstock for filter feeding aquatic organisms The present invention provides a method of cultivating filter feeders such as Artemia by substituting special microorganisms for naturally occurring microscopic algae, and providing conditions optimal for the growth of these organisms. These subsituted special micro... | 03/25/2008 |
| 7329410 | Compositions and method for WT1 specific immunotherapy A method for enhancing or inducing an immune response to WT1 is disclosed. In particular, the method comprises administering to a patient an immunogenic composition comprising an isolated polypeptide consisting of amino acids 1-249 of WT1 and a non-specific immune r... | 02/12/2008 |
| 7323182 | Oil in water emulsions containing saponins The present invention relates to an oil in water emulsion vaccine composition. In particular, the present invention relates to a vaccine adjuvant formulation based on oil in water emulsion comprising a metabolisable oil and a saponin, wherein the oil and a saponin a... | 01/29/2008 |
| 7311924 | Compositions and methods for treating cancer This invention provides compositions and methods for treating neoplasias in a mammal. In particular, the invention provides liposome-encapsulated vinca alkaloids, e.g., vinorelbine, and methods of treating a mammal using such compositions. ... | 12/25/2007 |
| 7309493 | Inactivated bovine scours vaccines, process and method of preventing bovine scours Inactivated scours vaccines for immunization and protection of bovine animals from disease caused by infection with bovine rotavirus and bovine coronavirus, which comprise and effective amount of at least one inactivated viral strain are described. Polyvalent inacti... | 12/18/2007 |
| 7276579 | Immunogenic proteoliposomes, and uses thereof An immunogenic proteoliposome containing a transmembrane protein or oligomeric complexes containing such proteins, including viral envelope glycoproteins, in a lipid membrane around an elliptoid or spherical shape. The shape preferably also contains an attractant su... | 10/02/2007 |
| 7273620 | Triggered release of liposomal drugs following mixing of cationic and anionic liposomes Methods and compositions for triggering the delivery of an encapsulated therapeutic agent from a liposome are provided. Liposomes of opposite charge and incorporating lipids which favor non-lamellar structures are contacted in vivo. At least one of the liposome enca... | 09/25/2007 |
| 7259012 | Use of oxidized lipoproteins for differentiation of precursor cells into mature dendritic cells The invention concerns a method for differentiating precursor cells into mature dendritic cells, comprising placing the precursor cells in a medium suitable for their differentiation and adding to the medium, in a predetermined amount, at least one fraction of oxidi... | 08/21/2007 |
| 7255867 | Vaccine Effective stimulation of immune responses is achieved through the use of a group A streptococcal antigen combined with proteosome adjuvant. The compositions are provided in particular for intranasal administration. The vaccine compositions are provided for use in in... | 08/14/2007 |
| 7250403 | Biodegradable immunomodulatory formulations and methods for use thereof The invention provides new compositions and methods for immunomodulation of individuals. Immunomodulation is accomplished by administration of immunomodulatory polynucleotide/microcarrier (IMP/MC) complexes. The IMP/MC complexes may be covalently or non-covalently b... | 07/31/2007 |
| 7247316 | Compositions and methods for treating lymphoma This invention provides methods for treating neoplasias in a mammal. In particular, the invention provides methods for treating various types of lymphomas, including relapsed forms of non-Hodgkin's Lymphoma. These methods involve the administration of liposome-encap... | 07/24/2007 |
| 7244450 | Compositions and methods for treating lymphoma This invention provides methods for treating neoplasias in a mammal. In particular, the invention provides methods for treating various types of lymphomas, including relapsed forms of non-Hodgkin's Lymphoma. These methods involve the administration of liposome-encap... | 07/17/2007 |
| 7223739 | Adjuvanted genetic vaccines Reagents useful in nucleic acid immunization techniques are described. More particularly, adjuvanted genetic vaccine compositions are described, as are methods of using those compositions for inducing an enhanced immune response against a selected antigen. ... | 05/29/2007 |
| 7189418 | Method for extracting lipid mixture containing phospholipids comprising polyunsaturated fatty acids from viscera of fish, method for preserving viscera prior to extraction, and lipid mixture extracted thereby The present invention provides a method for extracting a lipid mixture having a high percentage of phospholipids comprising polyunsaturated fatty acids. The method comprises the steps of (a) heating the viscera of fish with hot water or steam; and (b) extracting fro... | 03/13/2007 |
| 7147862 | Vaccine composition containing adjuvants The present invention provides vaccine compositions comprising 3 De-O-acylated monophosphoryl lipid A and QS21. The vaccines compositions are potent inducers of CTL and γ IFN responses. ... | 12/12/2006 |
| 7122191 | Microfluidized oil-in-water emulsions and vaccine compositions This invention provides submicron oil-in-water emulsions useful as a vaccine adjuvant for enhancing the immunogenicity of antigens. The present invention also provides vaccine compositions containing an antigen combined with such emulsions intrinsically or extrinsic... | 10/17/2006 |
| 7090840 | subsp. strain antibacterial against and 0157:h7 The present invention relates to novel lactic microorganism, method for preparation and uses thereof. Particularly, the present invention relates to novel Lactobacillus paracasei strain (Lactobacillus paracasei subsp. paracasei CSK 01) which is ... | 08/15/2006 |
| 7087236 | Method for inducing a cell-mediated immune response and improved parenteral vaccine formulations thereof A method of inducing either a TH1 polarized immune response, a TH2 polarized immune response or a combined TH1 and TH2 response to an antigen and associated vaccine formulations are disclosed. A method is provided for indu... | 08/08/2006 |
| 7078388 | DNA vaccines for farm animals, in particular bovines and porcines DNA vaccine against a pathogen affecting farm animals, in particular bovines or porcines, comprising a plasmid containing a nucleotide sequence encoding an immunogen of a pathogen of the animal species considered, under conditions allowing the in vivo expression of ... | 07/18/2006 |
| 7063855 | Composition for feeding prey organisms in aquaculture A composition is for feeding aquacultural prey organisms such as Artemia and rotifiers, comprising a lipid component comprising at least 25 wt % of phospholipids and providing a DHA content of at least 30 wt %. The lipid component is preferably derived from m... | 06/20/2006 |
| 7052704 | Methods and compositions for lipidization of hydrophilic molecules Fatty acid derivatives of sulfhydryl-containing compounds (for example, sulfhydryl-containing peptides or proteins) comprising fatty acid-conjugated products with a disulfide linkage are employed for delivery of the compounds to mammalian cells. This modification ma... | 05/30/2006 |
| 7033584 | Feeding Thraustochytriales to poultry for increasing omega-3 highly unsaturated fatty acids in eggs A process is provided for growing microflora of the order Thraustochytriales such as Thraustochytrium, Schizochytrium, and mixtures thereof, in fermentation medium containing non-chloride containing sodium salts, in particular sodium sulfate. In a preferred embodime... | 04/25/2006 |
| 7033612 | Composition and method for treating age-related disorders There is provided a composition for the prevention and treatment of age-related physical and mental disorders that includes phospholipids that have been extracted from chick embryos aged between about 6 days old and about 14 days old. Also provided is a method for e... | 04/25/2006 |
| 7022512 | Schizochytrium and thraustochytrium strains for producing high concentrations of omega-3 highly unsaturated fatty acids Disclosed is a process for growing the microflora Thraustochytrium, Schizochytrium, and mixtures thereof, which includes the growing of the microflora in fermentation medium containing non-chloride containing sodium salts, in particular sodium sulfate. In a p... | 04/04/2006 |
| 7011962 | Method of producing lipids by growing microorganisms of the order thraustochyriales Disclosed is a process for growing the microflora Thraustochytrium, Schizochytrium, and mixtures thereof, which includes the growing of the microflora in fermentation medium containing non-chloride containing sodium salts, in particular sodium sulfate. In a p... | 03/14/2006 |
| 7005280 | Method of producing lipids by growing microorganisms of the order thraustochytriales Disclosed is a process for growing the microflora Thraustochytrium, Schizochytrium, and mixtures thereof, which includes the growing of the microflora in fermentation medium containing non-chloride containing sodium salts, in particular sodium sulfate. In a p... | 02/28/2006 |