Class 424/276.1 - Characterized by molecular weight

Subclass of Class 424 - Drug, bio-affecting and body treating compositions
Definition: Subject matter wherein the allergen or component is characterized
No. of patents: 48
Last issue date: 02/15/2011

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Number	Title	Issue Date
7887821	Process for producing an allergen extract The present invention relates to a process for producing an allergen extract from a biological allergen source material comprising the steps of a) contacting the source material with a liquid extraction agent to produce a allergen extract mixture contai...	02/15/2011
7279295	Allergen The present invention relates to a novel allergen from timothy grass (Phleum pretense) pollen, Phl p11 as disclosed in SEQ ID NO:2, and use thereof as a reagent and in a diagnositic kit as well as for immunotherapy. ...	10/09/2007
7256263	Dermatophagoides proteins and uses thereof The present invention relates to high molecular weight Dermatophagoides proteins, nucleic acid molecules encoding such proteins, and therapeutic and diagnostic reagents derived from such proteins. ...	08/14/2007
7112333	T cell epitopes of ryegrass pollen allergen The present invention provides isolated peptides of Lol p V, a major protein allergen of the species Lolium perenne. Therapeutic peptides within the scope of the invention comprise at least one T cell epitope, or preferably at least two T cell epitopes of a p...	09/26/2006
6977076	Methods for obtaining from Chlorella extract polysaccharides having immunomodulating properties Chlorella extracts containing high molecular weight Chlorella polysaccharide and polysaccharide complexes show immune modulatory, specifically immune stimulatory, activity. The polysaccharide and polysaccharide complexes contain glucose and any combina...	12/20/2005
6974576	Chlorella composition having high molecular weight polysaccharides and polysaccharide complexes Chlorella extracts containing high molecular weight Chlorella polysaccharide and polysaccharide complexes show immune modulatory, specifically immune stimulatory, activity. The polysaccharide and polysaccharide complexes contain glucose and any combina...	12/13/2005
6911208	Antigenic protein originating in malassezia A substantially pure, isolated, antigenic protein from fungi of the genus Malassezia, characterized in that said antigenic protein has a binding ability to IgE antibodies from patients with allergies; an antigenic fragment derived from the antigenic protein; ...	06/28/2005
6432407	Antigenic protein originating in malassezia A substantially pure, isolated, antigenic protein from fungi of the genus Malassezia, characterized in that said antigenic protein has a binding ability to IgE antibodies from patients with allergoses; an antigenic fragment derived from the antigenic prot...	08/13/2002
6335019	Methods for treating sensitivity to protein allergen using peptides which include a T cell epitope recognized by a T cell receptor specific for the protein allergen Antigen E or Amb a I of ragweed pollen has been shown to be a family or families of proteins. cDNAs encoding Amb a I, the major human allergen of ragweed and Amb a II, peptides derived from Amb a I or Amb a II, antibodies against the peptides; and methods...	01/01/2002
6277383	Ryegrass pollen allergen The present invention provides nucleic acid sequences coding for two ryegrass pollen allergen Lol p Ib family members, purified Lol p Ib.1 and Lol p Ib.2 proteins and fragments thereof, methods of producing recombinant Lol p Ib.1 or Lol p Ib.2 or at least...	08/21/2001
6193971	Dictyocaulus viviparus antigen for diagnosing lungworm infestation and for vaccination An immunogenic protein (DV 18) isolated from lungworm Dictyocaulus viviparus including variants and fragments thereof, are described. DNA encoding such protein, methods of isolating and preparing such protein, antibodies against such protein, immunoassays...	02/27/2001
6063902	Ectoparasite histamine releasing factor, genes and uses thereof The present invention relates to ectoparasite histamine releasing factor (HRF) proteins; to ectoparasite HRF nucleic acid molecules, including those that encode such HRF proteins; to antibodies raised against such HRF proteins; and to compounds that inhib...	05/16/2000
6054125	Purified mite allergen The present invention is directed to novel purified and isolated mite allergens possessing mite allergen activity with a molecular weight of about 94,000, about 40,000, about 16,000 or about 14,000 as determined by SDS-PAGE, which can be isolated from ext...	04/25/2000
5973121	Immunoassay for peanut allergen Peanuts are a common cause of food hypersensitivity reactions. The sera of 10 patients who had atopic dermatitis and a positive double-blind placebo-controlled food challenge to peanut were used to investigate the major allergens of peanut. Crude Florunne...	10/26/1999
5932225	Vaccine comprising eimeria spp. gametocyte antigen Substantially purified Eimeria maxima gametocytes have been prepared and methods for their preparations are disclosed. A proteinaceous extract derived from the gametocytes comprises at least nine proteins of varying molecular weights. Vaccines for conferr...	08/03/1999
5876722	DNA encoding Derf II, the major mite allergen, host cells containing such DNA and methods for producing Derf II The invention provides a DNA encoding at least one part of genetic information of protein which has biochemical and immunological properties of a major allergen of Dermatophagoides farinae (Derf II)....	03/02/1999
5874401	Cedar pollen protein and use thereof in treating, preventing, and diagnosing pollenosis A protein having a molecular weight of 44,000-54,000 daltons, isoelectric point of 8.5-9.2 and specific sugar chain is prepared from a cedar pollen. The protein induces pollenosis and can be suitably used as desensitization agent because it induces immuno...	02/23/1999
5869263	Lymphocyte chemoattractant factor and uses thereof Disclosed is a substantially pure antibody which specifically binds a LCF polypeptide and methods of using such antibodies....	02/09/1999
5840316	Ryegrass pollen allergen The present invention provides nucleic acid sequences coding for two ryegrass pollen allergen Lol p Ib family members, purified Lol p Ib.1 and Lol p Ib.2 proteins and fragments thereof, methods of producing recombinant Lol p Ib.1 or Lol p Ib.2 or at least...	11/24/1998
5798099	DNA encoding Derf II, the major mite allergen, host cells containing such DNA and method for producing Derf II The invention provides a DNA encoding at least one part of genetic information of protein which has biochemical and immunological properties of a major allergen of Dermatophagoides farinae (Derf II)....	08/25/1998
5773010	Low molecular weight allergen obtained from Dermatophagoides farinae New purified mite allergens useful as pharmaceutical and diagnostic compositions for the treatment and diagnosis of mite allergic diseases are provided. Both allergens are contained in fecal extracts of mites in culture. The high molecular weight allergen...	06/30/1998
5747047	Purified mite allergen The present invention is directed to novel purified and isolated mite allergens possessing mite allergen activity with a molecular weight of about 94,000, about 40,000, about 16,000 or about 14,000 as determined by SDS-PAGE, which can be isolated from ext...	05/05/1998
5736362	Ryegrass pollen allergen The present invention provides nucleic acid sequences coding for two ryegrass pollen allergen Lol p Ib family members, purified Lol p Ib.1 and Lol p Ib.2 proteins and fragments thereof, methods of producing recombinant Lol p Ib.1 or Lol p Ib.2 or at least...	04/07/1998
5705159	Immunoreactive peptide sequence from a 43 KD human cancer antigen A tumor associated protein has been discovered to exhibit immunoreactivity to human monoclonal antibody L92. A ten amino acid peptide segment of the protein and a fourteen amino acid peptide which contains the ten amino acid peptide has also been isolated...	01/06/1998
5693495	Allergens of alder pollen and applications thereof This invention provides recombinant DNA molecules which code for polypeptides that exhibit the antigenicity of an Aln g I allergen of alder, Alnus sp., of a Cor a I allergen of hazel or of a Bet v I allergen of birch and other plants of the order Fageles,...	12/02/1997
5650151	Citrus proteins for use in field detection of citrus blight using immunological techniques The present invention relates to purified and isolated citrus blight, antigens and antibodies thereto leaf proteins which are specific indicators of the presence of citrus blight. The isolated and purified citrus blight leaf proteins are extracted from ci...	07/22/1997
5631221	Pollenosis-inducing polypeptide, process for preparing the same, and uses thereof A polypeptide having a molecular weight of 40,000&#b1;5,000 daltons and an isoelectric point of 9.5&#b1;0.5 is prepared from a cedar pollen. The polypeptide which induces pollenosis can be suitably used as desensitization agent because it induces immunogl...	05/20/1997
5558869	Major peanut allergen ara h II Peanut allergen Ara h II was identified using the sera of patients who had atopic dermatitis and a positive food challenge to peanut. The Ara h II allergen, having a molecular weight of 17 kD and a pI of 5.2, was isolated by anion exchange chromatography....	09/24/1996
5496550	Method of reducing the output of Eimeria oocysts from a newborn chick This invention provides a method of reducing the output of Eimeria oocysts from a newborn chick which comprises administering to a laying hen at a suitable time prior to the hen laying a fertilized egg an amount of native or recombinant antigenic protein ...	03/05/1996
5496554	Purified mite allergen New purified mite allergens useful as pharmaceutical and diagnostic compositions for the treatment and diagnosis of mite allergic diseases are provided. Both allergens are contained in fecal extracts of mites in culture. The high molecular weight allergen...	03/05/1996
5328991	Preparation of alkali-modified cat dander allergen (Fel d I) for immunotherapeutic purposes Proteins, referred to as modified human T cell reactive feline proteins, which have reduced ability to bind immunoglobulin E from cat allergic individuals and substantially unaltered ability to stimulate T cells from cat allergic individuals (relative to ...	07/12/1994
5314991	Recombinant 40 KDa Dermatophagoides farinae allergen The present invention is directed to a recombinant mite allergen obtainable by expression of a mite-body-derived gene, a gene which codes for said allergen, a mite allergen fragment, a polypeptide having an epitope contained in said allergen, an expressio...	05/24/1994
5073628	Hyposensitization agent A novel hyposensitization agent was prepared by covalently attaching a saccharide to a cedar pollen allergen having a partial amino acid sequence of Ala-Ile-Asn-Ile-Phe-Asn- beginning at its N-terminal. The hyposensitization agent, when compared with an i...	12/17/1991
4963356	Stable antigenic extracts methods A storage-stable, high potency allergenic extract is prepared by ultrafiltration, retaining fractions having molecular weights of from 1000 to 100,000, and drying the retained fraction to a moisture content of less than one weight percent. The extract can...	10/16/1990
4939239	Hyposensitization agent of cedar pollen antigen A novel hyposensitization agent was prepared by covalently attaching a saccharide, e.g. homo- and heteroglycans, for example, starch, amylose, dextran, polysucrose, pullulan, elsinan, curdlan, gum arabic, gum tragacanth, guar gum, xanthan gum carrageenan,...	07/03/1990
4716120	Stable allergenic extracts and methods A storage-stable, high potency allergenic extract is prepared by ultrafiltration, retaining fractions having molecular weights of from 1000 to 100,000, and treating the solution with gel polymer and/or carbon absorbents. The extract is dried to a moisture...	12/29/1987
4559230	Protein product, process for making it and pharmaceutical composition containing said protein New product consisting of glycoprotein having a molecular weight of about 14,000 and an isoelectric point of about 4.6, its absorption spectrum having an absorption of &3xb5;=0.12 units of optical density (O.D.) at 280 nm for an aqueous solution of 1 mg (...	12/17/1985
4554101	Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity An immunoglobulin is provided which consists essentially of a mono-specific, hetero-molecular antibody which is mono-specific to a single antigenic or allergenic determinant. The antibody is specific to the H-epitope of a protein antigen or allergen. The ...	11/19/1985
4552756	Allergenic compositions Improvement in the preparation of allergens, for the obtention of more stable and more effective preparations from extracts of various materials such as pollens, house dust, kapok, wool, molds, etc. extracts containing only allergenic substances having mo...	11/12/1985
4469677	Polypeptide active immunosuppressant fraction Immunosuppressive polypeptide fractions prepared by enzymatic digestion of specific allergens are non-reactive in animals and humans and effective by parenteral administration, the immunosuppression being antigen specific, affecting production of immunogl...	09/04/1984

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Class 424/276.1 - Characterized by molecular weight