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| Number | Title | Issue Date |
| 8080256 | Endophytic fungi from sp. plant, compounds and methods of use The present disclosure relates to endophytic fungi from higher plants such as a Pteromischum sp. plant, and to extracts and compounds from such fungi that have desirable biological activities, such as antifungal and immunosuppressive activities. The present d... | 12/20/2011 |
| 8003114 | AbfB-2 gene from The invention relates to the abfB-2 gene of Penicillium funiculosum that codes for a type B α-L-arabinofuranosidase and has a cellulose binding domain. This enzyme α-L-arabinofuranosidase can be incorporated in nutritional additives or in foods for animals ... | 08/23/2011 |
| 7972611 | Fungus-induced inflammation and eosinophil degranulation This document relates to methods and materials involved in fungus-induced inflammation and eosinophil degranulation. For example, isolated nucleic acids encoding fungal polypeptides, fungal polypeptides, methods for assessing fungus-induced inflammation, methods for... | 07/05/2011 |
| 7968106 | ABFB-1 gene of The invention relates to the abfB-1 gene of Penicillium funiculosum that codes for a type B α-L-arabinofuranosidase. This enzyme α-L-arabinofuranosidase can be incorporated in nutritional additives or in foods for animals for which it improves the digestibi... | 06/28/2011 |
| 7914799 | Anti-fungal composition A multivalent fungal vaccine comprising one or more heat-inactivated fungal antigens, wherein at least one fungal antigen is effective in producing an immune response in a host when said vaccine is administered orally at a dose that is sufficient for preventing or t... | 03/29/2011 |
| 7887820 | Fungus-induced inflammation and eosinophil degranulation This document relates to methods and materials involved in fungus-induced inflammation and eosinophil degranulation. For example, isolated nucleic acids encoding fungal polypeptides, fungal polypeptides, methods for assessing fungus-induced inflammation, methods for... | 02/15/2011 |
| 7815918 | Polypeptides and immunogenic conjugates capable of inducing antibodies against pathogens, and uses thereof A number of immunologically active agents are described, including an isolated protein or polypeptide that includes the amino acid sequence of SEQ ID NO: 1, immunogenic conjugates containing either the protein or polypeptide, a full-length Pneumocystis kexin,... | 10/19/2010 |
| 7815919 | Fungus-induced inflammation and eosinophil degranulation This document relates to methods and materials involved in fungus-induced inflammation and eosinophil degranulation. For example, isolated nucleic acids encoding fungal polypeptides, fungal polypeptides, methods for assessing fungus-induced inflammation, methods for... | 10/19/2010 |
| 7790188 | Antifungal protein and usage thereof The present invention relates to an antifungal protein gene and cDNA sequence thereof, which is obtained by mining the whole genome sequences of Monascus pilosus BCRC 38072 and the unigene database. The gene can encode an antifungal protein MAFP1. A purified ... | 09/07/2010 |
| 7722890 | Synthetic anti-oligosaccharide based vaccines The present invention provides methods of making and using immunogenic oligosaccharide compositions comprising native O-linked and S-linked oligosaccharides coupled to a protein carrier, wherein the resultant conjugate elicits a protectively immunogenic response. Th... | 05/25/2010 |
| 7666440 | Dermatomycosis vaccine The present invention relates to the preparation of universal inactivated vaccines and their use in preparing compositions for the prophylaxis and therapy of dermatomycosis. Vaccines according to the present invention have the advantage of conferring immunity agains... | 02/23/2010 |
| 7662400 | Fungus-induced inflammation and eosinophil degranulation This document relates to methods and materials involved in fungus-induced inflammation and eosinophil degranulation. For example, isolated nucleic acids encoding fungal polypeptides, fungal polypeptides, methods for assessing fungus-induced inflammation, methods for... | 02/16/2010 |
| 7655248 | Compositions and methods for treatment of candidiasis The present invention relates to novel oral compositions and vaccines, and in particular to oral vaccines for the prevention or therapy of candidiasis. ... | 02/02/2010 |
| 7435417 | Pharmaceutical composition containing disrupted cell suspension of and euglobulin and method of treating animals infected with canine distemper virus or animals having neurological disorders by using the same Disclosed is a pharmaceutical composition which comprises a disrupted cell suspension of Monilia albicans and euglobulin as effective ingredients, wherein the disrupted cell suspension of the Monilia albicans is prepared by culturing the Monilia alb... | 10/14/2008 |
| 7407944 | Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5′ ends The invention relates to the therapeutic use of oligonucleotides as immunostimulatory agents in immunotherapy applications. More particularly, the invention provides immunomers for use in methods for generating an immune response or for treating a patient in need of... | 08/05/2008 |
| 7368256 | Antibodies against and methods for their use Antibodies to various fungal antigens are disclosed, including monoclonal antibody 9B4 that selectively binds an antigen of Stachybotrys chartarum spores not found in Stachybotrys chartarum mycelium. The antibodies may be used in a variety of methods, ... | 05/06/2008 |
| 7332324 | Attenuated vaccine useful for immunizations against spp. infections A Coccidioides spp. fungus that is attenuated by the loss of endosporulation potential of the fungus wherein said fungus does not replicate when transformed into the parasitic phase. ... | 02/19/2008 |
| 7332167 | Nucleic acid and amino acid sequences of hemoglobin-response genes in and the use of reagents derived from these sequences in the diagnosis of disseminated infection Three hemoglobin-response genes in the pathogenic yeast Candida albicans are disclosed. The expression of these genes is specifically induced when the organism is exposed to hemoglobin during disseminated infections. The invention relates to the nucleic acid ... | 02/19/2008 |
| 7264819 | Lyase treatment for Infection by P. carinii can be treated by administering methioninase optionally in combination with additional therapeutic agents, such as antibiotics. ... | 09/04/2007 |
| 7258866 | -containing ringworm vaccine A ringworm vaccine is disclosed comprising antigen isolated from at least one dermatophyte and a suitable carrier. The “antigen” can include a single antigen from a dermatophyte or a plurality of antigens as long as at least one antigen is included which will pr... | 08/21/2007 |
| 7241613 | Identification of cell surface proteins and their uses The invention provides for novel polypeptides of Candida species found on the cell wall of the Candida organism. The invention further provides for methods of using these polypeptides, the genes encoding the polypeptides and fragments thereof for prepa... | 07/10/2007 |
| 7235246 | Dermatomycosis vaccine The present invention relates to the preparation of universal inactivated vaccines and their use in preparing compositions for the prophylaxis and therapy of dermatomycosis. Vaccines according to the present invention have the advantage of conferring immunity agains... | 06/26/2007 |
| 7217538 | : a gene, methods for making and using, and targeting it or its expression products for antifungal applications Disclosed and claimed is the CaESS1 gene, portions thereof such as primers or probes, expression products therefrom, and methods for using the gene, and expression products; for instance, for diagnostic, therapeutic or preventive compositions. ... | 05/15/2007 |
| 7138502 | Antibodies to the propeptide of and methods of use Antibodies and agents which can bind to the propeptide of the Int1p protein of yeast microorganisms such as Candida albicans are provided which can be useful in methods for treating or preventing infections arising from such microorganisms. Microorganisms exp... | 11/21/2006 |
| 7122176 | Mycoattractants and mycopesticides The present invention utilizes the pre-sporulation (preconidial) mycelial stage of entomopathogenic fungi as insect attractants and/or pathogens. The fungus can be cultivated on grain, wood, agricultural wastes or other cellulosic material, attracting the insect and... | 10/17/2006 |
| 7090857 | Antigenic preparations The present invention relates to antigenic preparations comprising polysaccharides and/or glycopeptides preparable from keratinophilic fungi as well as yeasts, process for the preparation of these antigenic preparations, their use as pharmaceutical substances as wel... | 08/15/2006 |
| 7083787 | Yeast-dendritic cell vaccines and uses thereof Disclosed is a vaccine that includes a dendritic cell loaded with a yeast vehicle and antigen. Also disclosed are methods of making the vaccine and using the vaccine to elicit cellular and humoral immune responses in a mammal. Additionally, a method to elicit an imm... | 08/01/2006 |
| 7078037 | Peptides and DNA encoding the peptides useful for immunizations against spp. infections The present invention provides compositions of peptides and polynucleotides encoding the peptides, which peptides are useful for generating an immunological response in an individual and in therapeutic and diagnostic applications of infections due to pathogenic C... | 07/18/2006 |
| 7070793 | Antigen protein and nucleic acid coding for said protein To provide a novel antigenic protein and a nucleic acid encoding the antigenic protein, which are useful for prophylaxis, treatment and diagnosis of diseases caused by fungi including Candida albicans. An antigenic protein characterized in that the antigenic ... | 07/04/2006 |
| 7067138 | Pharmaceutical compositions and methods to vaccinate against disseminated candidiasis A Candida albicans bloodstream infections cause significant morbidity and mortality in hospitalized patients. Filament formation and adherence to host cells are critical virulence factors of C. albicans. Multiple filamentation regulatory pathways have ... | 06/27/2006 |
| 7001757 | Protein This invention relates to polynucleotides, polypeptides encoded by these polynucleotides, to the production of such polynucleotides and polypeptides, and to the uses of such polynucleotides and polypeptides. More specifically, the invention relates to the phosphomev... | 02/21/2006 |
| 6977076 | Methods for obtaining from Chlorella extract polysaccharides having immunomodulating properties Chlorella extracts containing high molecular weight Chlorella polysaccharide and polysaccharide complexes show immune modulatory, specifically immune stimulatory, activity. The polysaccharide and polysaccharide complexes contain glucose and any combina... | 12/20/2005 |
| 6974576 | Chlorella composition having high molecular weight polysaccharides and polysaccharide complexes Chlorella extracts containing high molecular weight Chlorella polysaccharide and polysaccharide complexes show immune modulatory, specifically immune stimulatory, activity. The polysaccharide and polysaccharide complexes contain glucose and any combina... | 12/13/2005 |
| 6942867 | Antigen protein and nucleic acid coding for said protein To provide a novel antigenic protein and a nucleic acid encoding the antigenic protein, which are useful for prophylaxis, treatment and diagnosis of diseases caused by fungi including Candida albicans. An antigenic protein characterized in that the antigenic ... | 09/13/2005 |
| 6923973 | Peptide and DNA immunization against Coccidioides immitis infections Disclosed are peptide and DNA compositions surprisingly found to be effective in generating immune responses against the pathogenic fungi Coccidioides spp., the causative agents of coccidioidomycosis and Valley Fever. The invention thus provides peptides and ... | 08/02/2005 |
| 6872399 | Dermatomycosis vaccine The present invention relates to the preparation of universal inactivated vaccines and their use in preparing compositions for the prophylaxis and therapy of dermatomycosis. Vaccines according to the present invention have the advantage of conferring immunity agains... | 03/29/2005 |
| 6833136 | Vaccine for preventing pythiosis in humans and animals The present invention provides antigen vaccines and methods of use thereof for the treatment of Pythium insidiosum infections, as well as prophylaxis against these infections, in humans and mammals. Further, the present invention provides a method for prepari... | 12/21/2004 |
| 6800745 | Indolicidin analogs and methods of using same The present invention relates to analogs of indolicidin, which is a naturally occurring peptide having the amino acid sequence Ile-Leu-Pro-Trp-Lys-Trp-Pro-Trp-Trp-Pro-Trp-Arg-Arg-NH2 (“Indol 1-13;” SEQ ID NO: 1). The indolicidin analogs of the inventi... | 10/05/2004 |
| 6797276 | Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response A transcutaneous immunization system where the topical application of an adjuvant and an antigen or nucleic acid encoding for an antigen, to intact skin induces a ystemic or mucosol antibody response. The immune response so elicited can be enhanced by physical or ch... | 09/28/2004 |
| 6784203 | Cytokine production inhibitors A 5,6-dihydro-α-pyrone of formula (I) wherein R is CO2H or CH3 and, when R is CO2H, a pharmaceutically or veterinarily acceptable salt thereof. Processes for producing compounds of formu... | 08/31/2004 |
