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Class 424/270.1 - Babesia


Subclass of Class 424 - Drug, bio-affecting and body treating compositions
Definition: Subject matter wherein the parasitic protozoan is of the
No. of patents: 29
Last issue date: 09/21/2010


NumberTitleIssue Date
7799330Piroplasmid vaccine
The invention relates to a Piroplasmid protein or an immunogenic fragment of the protein, and to a nucleic acid encoding the Piroplasmid protein or immunogenic fragment. Furthermore, the invention relates to cDNA fragments, recombinant DNA molecules and live recombi...
09/21/2010
7479284vaccine
The present invention relates to nucleic acid sequences encoding novel Babesia canis associated proteins and to cDNA fragments, recombinant DNA molecules and live recombinant carriers comprising these sequences. Furthermore, the invention relates to host cell...
01/20/2009
7465459Piroplasmid vaccine
The invention relates to a Piroplasmid protein or an immunogenic fragment of the protein, and to a nucleic acid encoding the Piroplasmid protein or the immunogenic fragment. Furthermore, the invention relates to cDNA fragments, recombinant DNA molecules and live rec...
12/16/2008
7390626Methods and kit for diagnosing tick borne illnesses
ELISA, Western Blot, and a peptide-based ELISA were applied to clinical specimens from patients with clinical symptoms of tick borne diseases, including Lyme disease. Peptides from different components of Borrelia during different cycles, including peptides f...
06/24/2008
7326543Gene encoding protein from merozoite of , recombinant protein obtained with said gene and use thereof
The present invention provides a gene encoding a protein from merozoite of Babesia caballi, a recombinant protein of Babesia caballi, and an antibody capable specifically binding to a 48 kDa protein of rhoptry of Babesia caballi merozoite. In ac...
02/05/2008
7276232Formulation of microorganisms for use in bait gels for rodent control
The present invention relates to compositions containing different stages of pathogenic protozoans in a gel and to their use for controlling rodents. ...
10/02/2007
7090849vaccine
The present invention relates to nucleic acid sequences encoding novel Babesia canis associated proteins and to cDNA fragments, recombinant DNA molecules and live recombinant carriers comprising these sequences. Furthermore, the invention relates to host cell...
08/15/2006
7063967Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors
Aminoalkyl glucosaminide phosphate (AGP) compounds that are adjuvants and immunoeffectors are described and claimed. The compounds have a 2-deoxy-2-amino glucose in glycosidic linkage with an aminoalkyl (aglycon) group. Compounds are phosphorylated at the 4 or 6 car...
06/20/2006
6855319Gene encoding merozoite protein of Babesia caballi, recombinant protein obtained therefrom and utilization thereof
The present invention provides a gene encoding a protein from merozoite of Babesia caballi, a recombinant protein of Babesia caballi, and an antibody capable specifically binding to a 48 kDa protein of rhoptry of Babesia caballi merozoite. In ac...
02/15/2005
6607725Conjugate vaccine for nontypeable Haemophilus influenzae
A conjugate vaccine for Nontypeable Haemophilus influenzae comprising lipooligosaccharide from which esterified fatty acids have been removed conjugated to an immunogenic carrier. The vaccine is useful for prevention of otitis media and respiratory infect...
08/19/2003
6569433Compounds and methods for the diagnosis and treatment of B. microti infection
Compounds and methods for the diagnosis and treatment of B. microti infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a B. microti antigen and DNA sequences encoding such polypeptides. Anti...
05/27/2003
6451315Compounds and methods for the diagnosis and treatment of B. microti infection
Compounds and methods for the diagnosis and treatment of B. microti infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a B. microti antigen, DNA sequences encoding such polypeptides, and fus...
09/17/2002
6306396Compounds and methods for the diagnosis and treatment of B. microti infection
Compounds and methods for the diagnosis and treatment of B. microti infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a B. microti antigen and DNA sequences encoding such polypeptides. Anti...
10/23/2001
6183976Compounds and methods for the diagnosis and treatment of B. microti infection
Compounds and methods for the diagnosis and treatment of B. microti infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a B. microti antigen and DNA sequences encoding such polypeptides. Anti...
02/06/2001
6162433Non antibiotic selectable markers for live vaccines
The invention relates to DNA constructs encoding a safe, selectable marker, other than an antibiotic resistance marker, vectors and/or cells including said constructs; and vaccines based on said constructs for use in animals and particularly humans. The s...
12/19/2000
6045806Babesia vaccine
The invention is directed to a vaccine comprising Babesia canis antigens from a strain of Babesia canis rossi and another Babesia canis subspecies. Such a vaccine gives both homologous protection, and heterologous protection to infection with strains other tha...
04/04/2000
5824537Processes for the in vitro culture, attenuation of the virulence and cloning of parasites of the genus babesia and their applications
The present invention provides a process for the in vitro culture of parasites of the genus Babesia, processes for the in vitro attenuation of the virulence of these parasites, processes for the in vitro cloning of these parasites, attenuated parasites, c...
10/20/1998
5549898Immunogenic anaplasma marginale surface antigens, compositions, and methods of use
A purified antigenic surface protein of Anaplasma marginale has been identified, and is capable of inducing immune responses in ruminants which neutralizes virulent Anaplasma marginale. The antigenic surface protein has a molecular weight of about 105,000...
08/27/1996
5290688Method for intensive, in vitro culture of Babesia divergens strains
Method for the culture of Babesia divergens, characterized in that the Babesia strain is maintained under culture in a culture medium free from serous protein but containing lipoproteins and red blood corpuscles, and a method for preparing exoantigens and...
03/01/1994
5273884Polypetides, antigens or vaccines protective against babesiosis
An antigen which produces immunity against homologous or heterologous challenge with babesia of cattle. The antigen is immunoreactive with a monoclonal antibody or polyclonal antisera recognising a protein located on the surface of babesia-infected erythr...
12/28/1993
5209929Immunization against Babesiosis using purified merozoite surface antigens of Basesia bigemina
Antigenic surface proteins from the intraerythrocytic merozoite stage of Babesia bigemina have been isolated using cell fusions and monoclonal antibodies produced thereby. Immunization of mammals, such as bovines, with purified isolates induces an immunol...
05/11/1993
4777036Process for the culture of Babesia canis, application to the preparation of antigenes and vaccines and antigenes and vaccines against pyroplasmosis
In a process for the culture of Babesia canis, erythrocytes infected by the Babesia canis parasite are incubated in a culture medium suitable for the survival of the erythrocytes and for breeding of the parasites, in the presence of a homologous serum, in...
10/11/1988
4762711Live vaccine for bovine babesiosis
A live vaccine for bovine babesiosis comprises viable bovine erythrocytes parasitized with a cloned population of Babesia bovis, the clone strain being fast-growing, avirulent, and producing a mild but immunizing infection when administered. The vaccine i...
08/09/1988
4661348Babesiosis antigen and method for preparation
A method of preparation of babesiosis antigen including the steps of: (i) forming a crude babesiosis antigenic fraction which is derived from a lysate of Babesia infected erythrocytes or soluble fraction thereof; (ii) forming monoclonal antibody to said b...
04/28/1987
4621054Biologically active substance, process for preparing the substance and immunoactive composition
This invention relates to a biologically active substance which is a glycoprotein having a molecular weight of 3,000 to 5,000 and has activity to inhibit toxoplasma multiplication in homologous cells and heterologous cells. This invention also relates to ...
11/04/1986
4596707Babesia parasite antigen useful in vaccine and diagnostic reagent
Soluble antigen, specific for Babesia parasites, is isolated from growth media of Babesia-infected erythrocytes in cell culture and characterized, inter alia, by its ability to inhibit the capacity of specific Babesia serum antibodies to neutralize infect...
06/24/1986
4590072Live vaccine for bovine babesiosis and method of preparation
A live vaccine for bovine babesiosis comprises viable bovine erythrocytes parasitized with a cloned population of Babesia bovis, the clone strain being fast-growing, avirulent, and producing a mild but immunizing infection when administered. The vaccine i...
05/20/1986
4493825Purified and antigenically selective vaccines for domestic animals
Purified antigenically selective vaccines for domestic animals are prepared from microorganism cultures containing the immunizing agent by first complexing the immunizing agent with micro-particles having bound IgG antibodies specific for the immunizing a...
01/15/1985
4457915Babesiosis vaccine prepared from soluble parasitic antigen factors isolated from disintegration of Babesia infected erythrocites
This invention relates to a method of preparation of a babesiosis vaccine which involves treating a suspension of Babesia infected erythrocytes. The erythrocytes are disintegrated, separated into soluble and insoluble fractions and subsequently fibrinogen...
07/03/1984
 
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