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| Number | Title | Issue Date |
| 7799330 | Piroplasmid vaccine The invention relates to a Piroplasmid protein or an immunogenic fragment of the protein, and to a nucleic acid encoding the Piroplasmid protein or immunogenic fragment. Furthermore, the invention relates to cDNA fragments, recombinant DNA molecules and live recombi... | 09/21/2010 |
| 7479284 | vaccine The present invention relates to nucleic acid sequences encoding novel Babesia canis associated proteins and to cDNA fragments, recombinant DNA molecules and live recombinant carriers comprising these sequences. Furthermore, the invention relates to host cell... | 01/20/2009 |
| 7465459 | Piroplasmid vaccine The invention relates to a Piroplasmid protein or an immunogenic fragment of the protein, and to a nucleic acid encoding the Piroplasmid protein or the immunogenic fragment. Furthermore, the invention relates to cDNA fragments, recombinant DNA molecules and live rec... | 12/16/2008 |
| 7390626 | Methods and kit for diagnosing tick borne illnesses ELISA, Western Blot, and a peptide-based ELISA were applied to clinical specimens from patients with clinical symptoms of tick borne diseases, including Lyme disease. Peptides from different components of Borrelia during different cycles, including peptides f... | 06/24/2008 |
| 7326543 | Gene encoding protein from merozoite of , recombinant protein obtained with said gene and use thereof The present invention provides a gene encoding a protein from merozoite of Babesia caballi, a recombinant protein of Babesia caballi, and an antibody capable specifically binding to a 48 kDa protein of rhoptry of Babesia caballi merozoite. In ac... | 02/05/2008 |
| 7276232 | Formulation of microorganisms for use in bait gels for rodent control The present invention relates to compositions containing different stages of pathogenic protozoans in a gel and to their use for controlling rodents. ... | 10/02/2007 |
| 7090849 | vaccine The present invention relates to nucleic acid sequences encoding novel Babesia canis associated proteins and to cDNA fragments, recombinant DNA molecules and live recombinant carriers comprising these sequences. Furthermore, the invention relates to host cell... | 08/15/2006 |
| 7063967 | Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors Aminoalkyl glucosaminide phosphate (AGP) compounds that are adjuvants and immunoeffectors are described and claimed. The compounds have a 2-deoxy-2-amino glucose in glycosidic linkage with an aminoalkyl (aglycon) group. Compounds are phosphorylated at the 4 or 6 car... | 06/20/2006 |
| 6855319 | Gene encoding merozoite protein of Babesia caballi, recombinant protein obtained therefrom and utilization thereof The present invention provides a gene encoding a protein from merozoite of Babesia caballi, a recombinant protein of Babesia caballi, and an antibody capable specifically binding to a 48 kDa protein of rhoptry of Babesia caballi merozoite. In ac... | 02/15/2005 |
| 6607725 | Conjugate vaccine for nontypeable Haemophilus influenzae A conjugate vaccine for Nontypeable Haemophilus influenzae comprising lipooligosaccharide from which esterified fatty acids have been removed conjugated to an immunogenic carrier. The vaccine is useful for prevention of otitis media and respiratory infect... | 08/19/2003 |
| 6569433 | Compounds and methods for the diagnosis and treatment of B. microti infection Compounds and methods for the diagnosis and treatment of B. microti infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a B. microti antigen and DNA sequences encoding such polypeptides. Anti... | 05/27/2003 |
| 6451315 | Compounds and methods for the diagnosis and treatment of B. microti infection Compounds and methods for the diagnosis and treatment of B. microti infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a B. microti antigen, DNA sequences encoding such polypeptides, and fus... | 09/17/2002 |
| 6306396 | Compounds and methods for the diagnosis and treatment of B. microti infection Compounds and methods for the diagnosis and treatment of B. microti infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a B. microti antigen and DNA sequences encoding such polypeptides. Anti... | 10/23/2001 |
| 6183976 | Compounds and methods for the diagnosis and treatment of B. microti infection Compounds and methods for the diagnosis and treatment of B. microti infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a B. microti antigen and DNA sequences encoding such polypeptides. Anti... | 02/06/2001 |
| 6162433 | Non antibiotic selectable markers for live vaccines The invention relates to DNA constructs encoding a safe, selectable marker, other than an antibiotic resistance marker, vectors and/or cells including said constructs; and vaccines based on said constructs for use in animals and particularly humans. The s... | 12/19/2000 |
| 6045806 | Babesia vaccine The invention is directed to a vaccine comprising Babesia canis antigens from a strain of Babesia canis rossi and another Babesia canis subspecies. Such a vaccine gives both homologous protection, and heterologous protection to infection with strains other tha... | 04/04/2000 |
| 5824537 | Processes for the in vitro culture, attenuation of the virulence and cloning of parasites of the genus babesia and their applications The present invention provides a process for the in vitro culture of parasites of the genus Babesia, processes for the in vitro attenuation of the virulence of these parasites, processes for the in vitro cloning of these parasites, attenuated parasites, c... | 10/20/1998 |
| 5549898 | Immunogenic anaplasma marginale surface antigens, compositions, and methods of use A purified antigenic surface protein of Anaplasma marginale has been identified, and is capable of inducing immune responses in ruminants which neutralizes virulent Anaplasma marginale. The antigenic surface protein has a molecular weight of about 105,000... | 08/27/1996 |
| 5290688 | Method for intensive, in vitro culture of Babesia divergens strains Method for the culture of Babesia divergens, characterized in that the Babesia strain is maintained under culture in a culture medium free from serous protein but containing lipoproteins and red blood corpuscles, and a method for preparing exoantigens and... | 03/01/1994 |
| 5273884 | Polypetides, antigens or vaccines protective against babesiosis An antigen which produces immunity against homologous or heterologous challenge with babesia of cattle. The antigen is immunoreactive with a monoclonal antibody or polyclonal antisera recognising a protein located on the surface of babesia-infected erythr... | 12/28/1993 |
| 5209929 | Immunization against Babesiosis using purified merozoite surface antigens of Basesia bigemina Antigenic surface proteins from the intraerythrocytic merozoite stage of Babesia bigemina have been isolated using cell fusions and monoclonal antibodies produced thereby. Immunization of mammals, such as bovines, with purified isolates induces an immunol... | 05/11/1993 |
| 4777036 | Process for the culture of Babesia canis, application to the preparation of antigenes and vaccines and antigenes and vaccines against pyroplasmosis In a process for the culture of Babesia canis, erythrocytes infected by the Babesia canis parasite are incubated in a culture medium suitable for the survival of the erythrocytes and for breeding of the parasites, in the presence of a homologous serum, in... | 10/11/1988 |
| 4762711 | Live vaccine for bovine babesiosis A live vaccine for bovine babesiosis comprises viable bovine erythrocytes parasitized with a cloned population of Babesia bovis, the clone strain being fast-growing, avirulent, and producing a mild but immunizing infection when administered. The vaccine i... | 08/09/1988 |
| 4661348 | Babesiosis antigen and method for preparation A method of preparation of babesiosis antigen including the steps of: (i) forming a crude babesiosis antigenic fraction which is derived from a lysate of Babesia infected erythrocytes or soluble fraction thereof; (ii) forming monoclonal antibody to said b... | 04/28/1987 |
| 4621054 | Biologically active substance, process for preparing the substance and immunoactive composition This invention relates to a biologically active substance which is a glycoprotein having a molecular weight of 3,000 to 5,000 and has activity to inhibit toxoplasma multiplication in homologous cells and heterologous cells. This invention also relates to ... | 11/04/1986 |
| 4596707 | Babesia parasite antigen useful in vaccine and diagnostic reagent Soluble antigen, specific for Babesia parasites, is isolated from growth media of Babesia-infected erythrocytes in cell culture and characterized, inter alia, by its ability to inhibit the capacity of specific Babesia serum antibodies to neutralize infect... | 06/24/1986 |
| 4590072 | Live vaccine for bovine babesiosis and method of preparation A live vaccine for bovine babesiosis comprises viable bovine erythrocytes parasitized with a cloned population of Babesia bovis, the clone strain being fast-growing, avirulent, and producing a mild but immunizing infection when administered. The vaccine i... | 05/20/1986 |
| 4493825 | Purified and antigenically selective vaccines for domestic animals Purified antigenically selective vaccines for domestic animals are prepared from microorganism cultures containing the immunizing agent by first complexing the immunizing agent with micro-particles having bound IgG antibodies specific for the immunizing a... | 01/15/1985 |
| 4457915 | Babesiosis vaccine prepared from soluble parasitic antigen factors isolated from disintegration of Babesia infected erythrocites This invention relates to a method of preparation of a babesiosis vaccine which involves treating a suspension of Babesia infected erythrocytes. The erythrocytes are disintegrated, separated into soluble and insoluble fractions and subsequently fibrinogen... | 07/03/1984 |