The ice cream cone was invented at the St. Louis Worlds Fair by Ernest Hamwi in 1904. His waffle booth was next to an ice cream vendor who ran short of dishes. Hamwi rolled a waffle to hold ice cream and the cone was born.
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| Number | Title | Issue Date |
| 8128943 | Use of oxazole derivatives for controlling fish parasites The present invention relates to the use of compounds of formula (I), wherein R1, X, Y, Z and m are as defined in the description, in the free form or in salt form either alone or in combination with a vaccine component, for controlling fish parasites, in... | 03/06/2012 |
| 8110202 | Synthetic vaccine for tick control This invention is related to the field of immunology of protein biotechnology and particularly to the construction of synthetic immunogens which result, where inoculated, in the production by cattle of an immune response capable of lesion to the ticks feeding on the... | 02/07/2012 |
| 8097261 | Roundworm coproantigen detection A composition, device, kit and method for detecting the presence or absence of roundworm in a fecal sample. The composition, device, kit and method of the present invention may be used to confirm the presence or absence of roundworm in a fecal sample from a mammal t... | 01/17/2012 |
| 8057809 | Bioactive copepod-compositions, processes for the production thereof, and use thereof to prevent or treat hosts infested by phylogenetically similar ectoparasites The present invention relates to novel compositions comprising copepods, such as marine Calanus species, process for the production thereof and use of said compositions in the prevention and/or treatment of ectoparasite infestations in animals. Further the in... | 11/15/2011 |
| 7887817 | Process for preventing protozoal diseases A process for preventing a protozoal disease by the administration of an alkyl phosphocholine to a human being. ... | 02/15/2011 |
| 7887818 | vaccine Neospora caninum is the causal agent of bovine neosporosis which results in high levels of abortion. The protective efficacy of two Neospora antigens: Neospora cyclophilin (NcCyP) and NcSRS2 was evaluated. Mice vaccinated with recombinant (r) Nc... | 02/15/2011 |
| 7879342 | Vaccine adjuvant and making and using the same The present invention relates to a novel adjuvant and/or immunomodulator isolated from peanut skin extract, which may be useful in the preparation of immunogenic compositions and vaccines. The present invention also provides for a method of stimulating acquisition o... | 02/01/2011 |
| 7846458 | Method and vaccine for treatment of in humans and lower animals A method and vaccine for treatment of pythiosis in humans and animals is described. In particular a vaccine comprising a mixture of extracellular and intracellular proteins is described. The vaccine enables cures of chronic pythiosis in some patients. ... | 12/07/2010 |
| 7833537 | Use of parasitic biological agents for prevention and control of autoimmune diseases The invention relates to a method of treating an excessive immune response including an aberrant/enhanced Th1 response by administering a helminthic parasite preparation in an amount sufficient to reduce the excessive immune response in an individual. This invention... | 11/16/2010 |
| 7744907 | Ex vivo animal or challenge model as method to measure protective immunity directed against parasites and vaccines shown to be protective in the method The invention relates to an ex vivo animal or challenge model as a method to identify protective (recombinant) proteins and rapidly measure protective immunity in intestinal segments directed against parasites and vaccines directed against parasitic infections. The ... | 06/29/2010 |
| 7736660 | Roundworm coproantigen detection A composition, device, kit and method for detecting the presence or absence of roundworm in a fecal sample. The composition, device, kit and method of the present invention may be used to confirm the presence or absence of roundworm in a fecal sample from a mammal t... | 06/15/2010 |
| 7700120 | Adjuvancy and immune potentiating properties of natural products of The present invention relates to a method for potentiating a specific immune response to an antigen in a mammal in need thereof. The method comprises administering to the mammal an effective amount of Ov-ASP, or at least one subunit of Ov-ASP, and an antigenic moiet... | 04/20/2010 |
| 7595059 | Methods and compositions for detecting larval with a cloned diagnostic antigen Compositions and methods for the detection of Taenia solium and the diagnosis of T. solium infection are described. The nucleotide and amino acid sequences of the antigenic T. solium polypeptides gp50a, gp50b and gp50c are p... | 09/29/2009 |
| 7510720 | Vaccine to control equine protozoal myeloencephalitis in horses The present invention provides vaccines and methods for making the vaccines that actively or passively protect an equid or other animal against Sarcocystis neurona. In particular, the present invention provides vaccines that provide active immunity which comprise a ... | 03/31/2009 |
| 7438917 | Peptide sequences specific for the hepatic stages of bearing epitopes capable of stimulating the T lymphocytes The present invention relates to an in vitro diagnostic method for malaria in an individual comprising placing a tissue or a biological fluid taken from an individual in contact with a molecule or polypeptide composition, wherein said molecule or polypeptide composi... | 10/21/2008 |
| 7438916 | Therapeutic target for protozoal diseases A novel Fasciclin Related Adhesive Protein (FRAP) from Plasmodium and related parasites is provided as a target for therapeutic intervention in diseases caused by the parasites. FRAP has been shown to play a critical role in adhesion to, or invasion into, hos... | 10/21/2008 |
| 7431936 | Proteins involved in cytoadhesion of plasmodium falciparum ring-stage-infected erythrocytes, antibodies which bind to the proteins, and methods for detecting infection, stage of infection and vaccines for protecting against infection The present invention provides the RSP-1 and RSP-2 proteins which are involved in the cytoadhesion of P. falciparum during ring-stage infection of erythrocytes, antibodies which bind to the proteins, methods of screening for a P. falciparum infection, ... | 10/07/2008 |
| 7423137 | Nucleic acids encoding recombinant 56 and 82 kDa antigens from gametocytes of and their uses The present invention provides the recombinant cloning and sequencing of two of the major Eimeria maxima gametocyte antigens having molecular weights of 56 and 82 kDa and the expression of these recombinant antigens in an E. coli expression system usin... | 09/09/2008 |
| 7410771 | Reagent and method for detecting a sporozoite antigen A reagent and method for the specific and highly sensitive detection of C. parvum in which the reagent is an antibody for a soluble C. parvum sporozoite antigen and the method is an immunoassay in which the antibody is used to detect or quantify C. ... | 08/12/2008 |
| 7407944 | Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5′ ends The invention relates to the therapeutic use of oligonucleotides as immunostimulatory agents in immunotherapy applications. More particularly, the invention provides immunomers for use in methods for generating an immune response or for treating a patient in need of... | 08/05/2008 |
| 7396536 | Parasitic helminth cuticlin proteins and uses thereof The present invention relates to: parasitic helminth cuticlin proteins; parasitic helminth cuticlin nucleic acid molecules, including those that encode such cuticlin proteins; antibodies raised against such cuticlin proteins; and compounds that inhibit parasitic hel... | 07/08/2008 |
| 7390492 | Vaccine to control equine protozoal myeloencephalitis in horses The present invention provides vaccines and methods for making the vaccines that actively or passively protect an equid or other animal against Sarcocystis neurona. In particular, the present invention provides vaccines that provide active immunity which comp... | 06/24/2008 |
| 7387271 | Immunostimulatory combinations The present invention provides immunostimulatory combinations. Generally, the immunostimulatory combinations include a TLR agonist and a TNF/R agonist. Certain immunostimulatory combinations also may include an antigen. ... | 06/17/2008 |
| 7374773 | Application of entomopathogenic nematode-infected cadavars from hard-bodied arthropods for insect suppression Pesticidal and/or antimicrobial biological agent-infected hard-bodied arthropod cadavers, such as from the family Tenebrionidae are used to control pest and/or microbial infestations in agriculture, commercial and urban environments. ... | 05/20/2008 |
| 7361359 | isolate The present invention relates to a novel Neospora caninum isolate from Nowra and extracts thereof. The strain is useful in the development of diagnostic assays for the detection of parasites in animals. The present invention also relates to pharmaceutical com... | 04/22/2008 |
| 7354593 | Coccidial vaccine and methods of making and using same The present invention relates to a vaccine for coccidiosis in chickens prepared from three attenuated Eimeria species: E. acervulina, E. maxima and E. tenella. The vaccine was similar to or superior to other anticoccidial drugs in stimulating pr... | 04/08/2008 |
| 7335736 | Compositions and methods for detecting Methods for the specific and highly sensitive detection of Treponema pallidum infection comprising the use of specific antigenic proteins and peptides unique to Treponema pallidum are provided. In particular, detection assays based on recognition of ac... | 02/26/2008 |
| 7326543 | Gene encoding protein from merozoite of , recombinant protein obtained with said gene and use thereof The present invention provides a gene encoding a protein from merozoite of Babesia caballi, a recombinant protein of Babesia caballi, and an antibody capable specifically binding to a 48 kDa protein of rhoptry of Babesia caballi merozoite. In ac... | 02/05/2008 |
| 7312350 | Process for preparing arylalkynes The invention relates to a process for preparing arylvinyl halides and sulphonates and arylalkynes by reacting haloaromatics or aryl sulphonates with vinyl halides or sulphonates in the presence of a palladium catalyst and a base and, if appropriate, subsequent elim... | 12/25/2007 |
| 7306806 | Recombinant merozoite protein-142 vaccine In this application is the expression and purification of a recombinant Plasmodium falciparum (3D7) MSP-142. The method of the present invention produces a highly purified protein which retains folding and disulfide bridging of the native molecule.... | 12/11/2007 |
| 7285274 | Baculovirus produced vaccine Compositions and methods are provided for the induction of a protective immunize response in primates against a lethal challenge of Plasmodium. ... | 10/23/2007 |
| 7282210 | Process for the in vitro culture of different stages of tissular parasites The present invention provides a method for carrying out in vitro the complete developmental sequence culture of tissular parasites, which includes culturing the parasites in a totally defined culture medium which is an axenic . . . monophasic liquid culture medium,... | 10/16/2007 |
| 7276232 | Formulation of microorganisms for use in bait gels for rodent control The present invention relates to compositions containing different stages of pathogenic protozoans in a gel and to their use for controlling rodents. ... | 10/02/2007 |
| 7273709 | Detection of sarcocystis neurona A gene encoding a 29 kilodalton protein found on the surface of merozoite stage S. neurona has been cloned and sequenced. The protein encoded by this gene, termed SnSAG-1, is an immunodominant antigen recognized on protein blots. Methods for using nucleic aci... | 09/25/2007 |
| 7264812 | vaccine The present invention relates to nucleic acid sequences encoding Ostertagia ostertagi proteins and to parts of such nucleic acid sequences that encode an immunogenic fragment of such proteins, and to DNA fragments, recombinant DNA molecules, live recombinant ... | 09/04/2007 |
| 7256281 | Recombinant merozoite protein-1vaccine In this application is described the expression and purification of a recombinant Plasmodium falciparum (FVO) MSP-142. The method of the present invention produces a highly purified protein that retains folding and disulfide bridging of the native ... | 08/14/2007 |
| 7250173 | Use of parasitic biological agents for prevention and control of autoimmune diseases The invention relates to a method of treating an excessive immune response including an aberrant/enhanced Th1 response by administering a helminthic parasite preparation in an amount sufficient to reduce the excessive immune response in an individual. This invention... | 07/31/2007 |
| 7235246 | Dermatomycosis vaccine The present invention relates to the preparation of universal inactivated vaccines and their use in preparing compositions for the prophylaxis and therapy of dermatomycosis. Vaccines according to the present invention have the advantage of conferring immunity agains... | 06/26/2007 |
| 7230075 | Coccidiosis poultry vaccine This invention relates to novel Eimeria proteins with immunogenic properties as well as to DNA sequences encoding these proteins. These proteins can be administered to poultry thereby protecting the birds against coccidiosis. In addition the DNA encoding thes... | 06/12/2007 |
| 7214784 | Protective antigens for the control of species infestations Protective antigens against infestations with Ixodes spp. ticks, gene sequences and encoded proteins for such antigens, related vaccines and methods useful to induce an immune response, which are protective to interfere with infestations by Ixodes spp.... | 05/08/2007 |